Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Somatic mosaicism across mouse tissues during different life stages
Zhang, L. (PI), Kennedy, J. M. (Graduate Student), Jung, H. (Other Role) & Zheng, C. (Other Role)
NIH NIGMS NATL INST OF GENERAL
8/13/25 → 5/31/30
Project: Research project
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Project 1_Genetic variant-based drug discovery targeting conserved pathways of aging
Dong, X. (PI) & Zhang, L. (CoI)
ALBERT EINSTEIN COLLEGE OF MEDICINE, NIH NATIONAL INSTITUTE ON AGING
9/1/23 → 8/31/26
Project: Research project
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Single-cell epigenomic analysis of premature aging syndromes
Zhang, L. (PI)
AMERICAN FEDERATION FOR AGING RESEARCH
7/1/22 → 6/30/24
Project: Research project
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SomaMutDB 2.0: A comprehensive database for exploring somatic mutations and their functional impact in normal human tissues
Shea, A., Sun, S., Kennedy, J., Zhang, L., Vijg, J. & Dong, X., Jan 6 2026, In: Nucleic acids research. 54, 1, p. D1291-D1300Research output: Contribution to journal › Article › peer-review
Open Access -
Divergent accumulation patterns of SNVs and INDELs reveal negative selection in noncancerous cells
Zhang, L., Lee, M., Hao, X., Ma, X., Xia, C., Zhao, Y., Ehlert, J., Chi, Z., Jin, B., Cutler, R., Maslov, A. Y., Barabási, A. L., Hoeijmakers, J. H. J., Edelmann, W., Vijg, J. & Dong, X., Oct 6 2025, In: Innovation. 6, 10, 101008.Research output: Contribution to journal › Article › peer-review
Open Access -
Human Cell Aging Transcriptome Atlas (HCATA): a single-cell atlas of age-associated transcriptomic alterations across human tissues
Bartz, J., Ma, X., Zhang, L. & Dong, X., Dec 2025, In: Communications biology. 8, 1, 1450.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations -
The Fifth Annual Symposium of the Midwest Aging Consortium
Reader, B. F., Rosas, L., Knopf, B. A., Liu, Y., Alzate-Correa, D., Bhat, A., Carey, A., Cuervo, A. M., Dayal, S., Demarco, R. S., Elliehausen, C. J., Englund, D. A., Hamilton, H. L., Johnston, M., Kang, P., Konopka, A. R., Lepola, N., Presley, C. J., Schafer, M. J. & Serrano, J. & 14 others, , Feb 1 2025, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 80, 2, glae296.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Analyzing somatic mutations by single-cell whole-genome sequencing
Zhang, L., Lee, M., Maslov, A. Y., Montagna, C., Vijg, J. & Dong, X., Feb 2024, In: Nature Protocols. 19, 2, p. 487-516 30 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Link opens in a new tab Scopus citations