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Research Output

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Review article
2019

Cellular Senescence: Defining a Path Forward

Gorgoulis, V., Adams, P. D., Alimonti, A., Bennett, D. C., Bischof, O., Bishop, C., Campisi, J., Collado, M., Evangelou, K., Ferbeyre, G., Gil, J., Hara, E., Krizhanovsky, V., Jurk, D., Maier, A. B., Narita, M., Niedernhofer, L., Passos, J. F., Robbins, P. D., Schmitt, C. A. & 6 others, Sedivy, J., Vougas, K., von Zglinicki, T., Zhou, D., Serrano, M. & Demaria, M., Oct 31 2019, In : Cell. 179, 4, p. 813-827 15 p.

Research output: Contribution to journalReview article

41 Scopus citations
2018

Development of clinical trials to extend healthy lifespan

Justice, J. N., Niedernhofer, L. J., Robbins, P. D., Aroda, V. R., Espeland, M. A., Kritchevsky, S. B., Kuchel, G. A. & Barzilai, N., Dec 1 2018, In : Cardiovascular Endocrinology and Metabolism. 7, 4, p. 80-83 4 p.

Research output: Contribution to journalReview article

11 Scopus citations

Hsp90 inhibitors as senolytic drugs to extend healthy aging

Fuhrmann-Stroissnigg, H., Niedernhofer, L. J. & Robbins, P. D., May 3 2018, In : Cell Cycle. 17, 9, p. 1048-1055 8 p.

Research output: Contribution to journalReview article

Open Access
8 Scopus citations

Nuclear Genomic Instability and Aging

Niedernhofer, L. J., Gurkar, A. U., Wang, Y., Vijg, J., Hoeijmakers, J. H. J. & Robbins, P. D., Jun 20 2018, In : Annual Review of Biochemistry. 87, p. 295-322 28 p.

Research output: Contribution to journalReview article

17 Scopus citations
2017

Molecular pathology endpoints useful for aging studies

Niedernhofer, L. J., Kirkland, J. L. & Ladiges, W., May 1 2017, In : Ageing Research Reviews. 35, p. 241-249 9 p.

Research output: Contribution to journalReview article

Open Access
26 Scopus citations
2016

Occurrence, Biological Consequences, and Human Health Relevance of Oxidative Stress-Induced DNA Damage

Yu, Y., Cui, Y., Niedernhofer, L. J. & Wang, Y., Dec 19 2016, In : Chemical research in toxicology. 29, 12, p. 2008-2039 32 p.

Research output: Contribution to journalReview article

45 Scopus citations

The Geropathology research network: An interdisciplinary approach for integrating pathology into research on aging

Ladiges, W., Ikeno, Y., Niedernhofer, L., Mcindoe, R. A., Ciol, M. A., Ritchey, J. & Liggitt, D., Apr 1 2016, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 71, 4, p. 431-434 4 p.

Research output: Contribution to journalReview article

Open Access
4 Scopus citations
2015

Comparison of mice with accelerated aging caused by distinct mechanisms

Gurkar, A. U. & Niedernhofer, L. J., Aug 1 2015, In : Experimental Gerontology. 68, p. 43-50 8 p.

Research output: Contribution to journalReview article

18 Scopus citations
2013

An overview of underlying causes and animal models for the study of age-related degenerative disorders of the spine and synovial joints

Vo, N., Niedernhofer, L. J., Nasto, L. A., Jacobs, L., Robbins, P. D., Kang, J. & Evans, C. H., Jun 1 2013, In : Journal of Orthopaedic Research. 31, 6, p. 831-837 7 p.

Research output: Contribution to journalReview article

53 Scopus citations
2011

Dedifferentiation rescues senescence of progeria cells but only while pluripotent

Niedernhofer, L. J., Glorioso, J. C. & Robbins, P. D., Sep 9 2011, In : Stem Cell Research and Therapy. 2, 3, 28.

Research output: Contribution to journalReview article

10 Scopus citations

ERCC1 and XRCC1 as biomarkers for lung and head and neck cancer

Vaezi, A., Feldman, C. H. & Niedernhofer, L. J., Dec 22 2011, In : Pharmacogenomics and Personalized Medicine. 4, 1, p. 47-63 17 p.

Research output: Contribution to journalReview article

26 Scopus citations

NF-κB in aging and disease

Tilstra, J. S., Clauson, C. L., Niedernhofer, L. J. & Robbins, P. D., Jan 1 2011, In : Aging and Disease. 2, 6, p. 449-465 17 p.

Research output: Contribution to journalReview article

151 Scopus citations

Physiological consequences of defects in ERCC1-XPF DNA repair endonuclease

Gregg, S. Q., Robinson, A. R. & Niedernhofer, L. J., Jul 15 2011, In : DNA Repair. 10, 7, p. 781-791 11 p.

Research output: Contribution to journalReview article

87 Scopus citations
2009

Mouse models of Fanconi anemia

Parmar, K., D'Andrea, A. & Niedernhofer, L. J., Jul 31 2009, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 668, 1-2, p. 133-140 8 p.

Research output: Contribution to journalReview article

88 Scopus citations
2008

Nucleotide excision repair deficient mouse models and neurological disease

Niedernhofer, L. J., Jul 1 2008, In : DNA Repair. 7, 7, p. 1180-1189 10 p.

Research output: Contribution to journalReview article

33 Scopus citations
2005

Fanconi anemia (cross)linked to DNA repair

Niedernhofer, L. J., Lalai, A. S. & Hoeijmakers, J. H. J., Dec 29 2005, In : Cell. 123, 7, p. 1191-1198 8 p.

Research output: Contribution to journalReview article

230 Scopus citations
2003

Divide and conquer: Nucleotide excision repair battles cancer and ageing

Mitchell, J. R., Hoeijmakers, J. H. J. & Niedernhofer, L. J., Apr 2003, In : Current Opinion in Cell Biology. 15, 2, p. 232-240 9 p.

Research output: Contribution to journalReview article

113 Scopus citations