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Kyle B Williams

20102020

Research output per year

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Projects

Exploiting Synthetic Lethality to Reveal Novel Vulnerabi

Williams, K. B.

CHILDRENS TUMOR FDN

7/3/17 → 7/3/19

Project: Research project

    • Research Output

    PLX3397 treatment inhibits constitutive CSF1R-induced oncogenic ERK signaling, reduces tumor growth, and metastatic burden in osteosarcoma

    Smeester, B. A., Slipek, N. J., Pomeroy, E. J., Laoharawee, K., Osum, S. H., Larsson, A. T., Williams, K. B., Stratton, N., Yamamoto, K., Peterson, J. J., Rathe, S. K., Mills, L. J., Hudson, W. A., Crosby, M. R., Wang, M., Rahrmann, E. P., Moriarity, B. S. & Largaespada, D. A., Jul 2020, In : Bone. 136, 115353.

    Research output: Contribution to journal › Article

    • The Anti-sigma Factor RsiV Is a Bacterial Receptor for Lysozyme: Co-crystal Structure Determination and Demonstration That Binding of Lysozyme to RsiV Is Required for σV Activation

    Hastie, J. L., Williams, K. B., Bohr, L. L., Houtman, J. C., Gakhar, L. & Ellermeier, C. D., Sep 2016, In : PLoS Genetics. 12, 9, e1006287.

    Research output: Contribution to journal › Article

    Open Access
    • 14 Scopus citations

    Clostridium difficile extracytoplasmic function σ factor σV regulates lysozyme resistance and is necessary for pathogenesis in the hamster model of infection

    Ho, T. D., Williams, K. B., Chen, Y., Helm, R. F., Popham, D. L. & Ellermeier, C. D., 2014, In : Infection and immunity. 82, 6, p. 2345-2355 11 p.

    Research output: Contribution to journal › Article

    • 24 Scopus citations

    Evidence of a Bacterial Receptor for Lysozyme: Binding of Lysozyme to the Anti-σ Factor RsiV Controls Activation of the ECF σ Factor σV

    Hastie, J. L., Williams, K. B., Sepúlveda, C., Houtman, J. C., Forest, K. T. & Ellermeier, C. D., Oct 1 2014, In : PLoS genetics. 10, 10

    Research output: Contribution to journal › Article

    • 23 Scopus citations

    Identification and characterization of a gene cluster required for proper rod shape, cell division, and pathogenesis in Clostridium difficile

    Ransom, E. M., Williams, K. B., Weiss, D. S. & Ellermeier, C. D., 2014, In : Journal of bacteriology. 196, 12, p. 2290-2300 11 p.

    Research output: Contribution to journal › Article

    • 24 Scopus citations