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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Projects
- 1 Finished
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Implication of znf217 in accelerating tumor development and therapeutically targeting ZNF217-induced PI3K–AKT signaling for the treatment of metastatic osteosarcoma
Smeester, B. A., Draper, G. M., Slipek, N. J., Larsson, A. T., Stratton, N., Pomeroy, E. J., Becklin, K. L., Yamamoto, K., Williams, K. B., Laoharawee, K., Peterson, J. J., Abrahante, J. E., Rathe, S. K., Mills, L. J., Crosby, M. R., Hudson, W. A., Rahrmann, E. P., Largaespada, D. A. & Moriarity, B. S., Dec 1 2020, In: Molecular Cancer Therapeutics. 19, 12, p. 2528-2541 14 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
New model systems and the development of targeted therapies for the treatment of neurofibromatosis type 1-associated malignant peripheral nerve sheath tumors
Williams, K. B. & Largaespada, D. A., Apr 28 2020, In: Genes. 11, 5, 477.Research output: Contribution to journal › Review article › peer-review
Open Access15 Scopus citations -
PLX3397 treatment inhibits constitutive CSF1R-induced oncogenic ERK signaling, reduces tumor growth, and metastatic burden in osteosarcoma
Smeester, B. A., Slipek, N. J., Pomeroy, E. J., Laoharawee, K., Osum, S. H., Larsson, A. T., Williams, K. B., Stratton, N., Yamamoto, K., Peterson, J. J., Rathe, S. K., Mills, L. J., Hudson, W. A., Crosby, M. R., Wang, M., Rahrmann, E. P., Moriarity, B. S. & Largaespada, D. A., Jul 2020, In: Bone. 136, 115353.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Targeted inhibition of the dual specificity phosphatases DUSP1 and DUSP6 suppress MPNST growth via JNK
Ramkissoon, A., Chaney, K. E., Milewski, D., Williams, K. B., Williams, R. L., Choi, K., Miller, A., Kalin, T. V., Pressey, J. G., Szabo, S., Azam, M., Largaespada, D. A. & Ratner, N., 2019, In: Clinical Cancer Research. 25, 13, p. 4117-4127 11 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
Genetically engineered minipigs model the major clinical features of human neurofibromatosis type 1
Isakson, S. H., Rizzardi, A. E., Coutts, A. W., Carlson, D. F., Kirstein, M. N., Fisher, J., Vitte, J., Williams, K. B., Pluhar, G. E., Dahiya, S., Widemann, B. C., Dombi, E., Rizvi, T., Ratner, N., Messiaen, L., Stemmer-Rachamimov, A. O., Fahrenkrug, S. C., Gutmann, D. H., Giovannini, M., Moertel, C. L. & 2 others, , Dec 1 2018, In: Communications biology. 1, 1, 158.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations