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Research Output 2008 2019

2019
Right Ventricular Dysfunction
Pulmonary Hypertension
Lung Diseases
Heart Ventricles
Chronic Disease

Repurposing medications for treatment of pulmonary arterial hypertension: What’s old is new again

Prins, K. W., Thenappan, T., Weir, E. K., Kalra, R., Pritzker, M. R. & Archer, S. L., Jan 1 2019, In : Journal of the American Heart Association. 8, 1, e011343.

Research output: Contribution to journalReview article

Right Ventricular Function
Pulmonary Hypertension
Pulmonary Artery
Lung Volume Measurements
Carbon Monoxide
Pulmonary Hypertension
Lung Diseases
Chronic Disease
2018
3 Citations (Scopus)

Disproportionate right ventricular dysfunction and poor survival in group 3 pulmonary hypertension

Prins, K. W., Rose, L., Archer, S. L., Pritzker, M. R., Weir, E. K., Kazmirczak, F., Misialek, J. R. & Thenappan, T., Jun 1 2018, In : American journal of respiratory and critical care medicine. 197, 11, p. 1496-1499 4 p.

Research output: Contribution to journalLetter

Right Ventricular Dysfunction
Pulmonary Hypertension
Cardiomyopathies
Knockout Mice
Dystrophin
Duchenne Muscular Dystrophy
Muscle Cells
10 Citations (Scopus)

Interleukin-6 is independently associated with right ventricular function in pulmonary arterial hypertension

Prins, K. W., Archer, S. L., Pritzker, M., Rose, L., Weir, E. K., Sharma, A. & Thenappan, T., Mar 1 2018, In : Journal of Heart and Lung Transplantation. 37, 3, p. 376-384 9 p.

Research output: Contribution to journalArticle

Right Ventricular Function
Pulmonary Hypertension
Interleukin-6
Right Ventricular Dysfunction
Lung Compliance
2017
9 Citations (Scopus)
Pulmonary Hypertension
Meta-Analysis
Therapeutics
Chronic Obstructive Pulmonary Disease
Randomized Controlled Trials
9 Citations (Scopus)
Right Ventricular Function
Colchicine
Pulmonary Hypertension
Microtubules
Monocrotaline
2016
9 Citations (Scopus)

Microtubule-Mediated Misregulation of Junctophilin-2 Underlies T-Tubule Disruptions and Calcium Mishandling in mdx Mice

Prins, K. W., Asp, M. L., Zhang, H., Wang, W. & Metzger, J. M., Apr 1 2016, In : JACC: Basic to Translational Science. 1, 3, p. 122-130 9 p.

Research output: Contribution to journalReview article

Inbred mdx Mouse
Microtubules
Cardiac Myocytes
Calcium
Calcium Signaling
5 Citations (Scopus)

Pulmonary pulse wave transit time is associated with right ventricular–pulmonary artery coupling in pulmonary arterial hypertension

Prins, K. W., Weir, E. K., Archer, S. L., Markowitz, J., Rose, L., Pritzker, M., Madlon-Kay, R. & Thenappan, T., Dec 1 2016, In : Pulmonary Circulation. 6, 4, p. 576-585 10 p.

Research output: Contribution to journalArticle

Pulse Wave Analysis
Pulmonary Hypertension
Arteries
Lung
Arterial Pressure
33 Citations (Scopus)

The critical role of pulmonary arterial compliance in pulmonary hypertension

Thenappan, T., Prins, K. W., Pritzker, M. R., Scandurra, J., Volmers, K. & Weir, E. K., Feb 1 2016, In : Annals of the American Thoracic Society. 13, 2, p. 276-284 9 p.

Research output: Contribution to journalReview article

Lung Compliance
Pulmonary Hypertension
Vascular Resistance
Pulmonary Artery
Pressure
15 Citations (Scopus)

World Health Organization Group I Pulmonary Hypertension: Epidemiology and Pathophysiology

Prins, K. W. & Thenappan, T., Aug 1 2016, In : Cardiology Clinics. 34, 3, p. 363-374 12 p.

Research output: Contribution to journalReview article

Pulmonary Hypertension
Epidemiology
Registries
Right Ventricular Dysfunction
National Institutes of Health (U.S.)
2015
11 Citations (Scopus)

Assessing continuous renal replacement therapy as a rescue strategy in cardiorenal syndrome 1

Prins, K. W., Wille, K. M., Tallaj, J. A. & Tolwani, A. J., Dec 18 2015, In : Clinical Kidney Journal. 8, 1, p. 87-92 6 p.

Research output: Contribution to journalArticle

Cardio-Renal Syndrome
Renal Replacement Therapy
Hospital Mortality
Heart Failure
Survivors
6 Citations (Scopus)
Cardio-Renal Syndrome
Heart Failure
Kidney
Acute Kidney Injury
Therapeutics
37 Citations (Scopus)

Effects of Beta-Blocker Withdrawal in Acute Decompensated Heart Failure. A Systematic Review and Meta-Analysis.

Prins, K. W., Neill, J. M., Tyler, J. O., Eckman, P. M. & Duval, S., Aug 1 2015, In : JACC: Heart Failure. 3, 8, p. 647-653 7 p.

Research output: Contribution to journalArticle

Meta-Analysis
Heart Failure
Hospital Mortality
Mortality
Confidence Intervals
10 Citations (Scopus)
Pulmonary Hypertension
Heart Failure
Right Ventricular Dysfunction
Therapeutics
Epidemiology
10 Citations (Scopus)

Pulmonary hypertension secondary to heart failure with preserved ejection fraction

Thenappan, T., Prins, K. W., Cogswell, R. & Shah, S. J., Apr 1 2015, In : Canadian Journal of Cardiology. 31, 4, p. 430-439 10 p.

Research output: Contribution to journalArticle

Pulmonary Hypertension
Heart Failure
Right Ventricular Dysfunction
Therapeutics
Epidemiology
2013
1 Citation (Scopus)

Characterization of 25+year survivors of cardiac transplantation

Prins, K. W., Masri, C., Colvin-Adams, M. & Eckman, P. M., May 1 2013, In : Journal of Heart and Lung Transplantation. 32, 5, p. 560-562 3 p.

Research output: Contribution to journalLetter

Right Ventricular Dysfunction
Heart Transplantation
Vascular Diseases
Longitudinal Studies
Young Adult
2011
17 Citations (Scopus)

Quadriceps myopathy caused by skeletal muscle-specific ablation of βcyto-actin

Prins, K. W., Call, J. A., Lowe, D. A. & Ervasti, J. M., Mar 15 2011, In : Journal of Cell Science. 124, 6, p. 951-957 7 p.

Research output: Contribution to journalArticle

Muscular Diseases
Dystrophin
Actins
Skeletal Muscle
Spectrin
2009
25 Citations (Scopus)

Context-dependent functional substitution of α-skeletal actin by γ-cytoplasmic actin

Jaeger, M. A., Sonnemann, K. J., Fitzsimons, D. P., Prins, K. W. & Ervasti, J. M., Jul 1 2009, In : FASEB Journal. 23, 7, p. 2205-2214 10 p.

Research output: Contribution to journalArticle

Actins
Substitution reactions
Muscle
Muscles
Transgenic Mice
99 Citations (Scopus)

Dystrophin is a microtubule-associated protein

Prins, K. W., Humston, J. L., Mehta, A., Tate, V., Ralston, E. & Ervasti, J. M., Aug 10 2009, In : Journal of Cell Biology. 186, 3, p. 363-369 7 p.

Research output: Contribution to journalArticle

Dystrophin
Microtubule-Associated Proteins
Microtubules
Tubulin
Costameres
2008
13 Citations (Scopus)

Destabilization of the dystrophin-glycoprotein complex without functional deficits in α-dystrobrevin null muscle

Bunnell, T. M., Jaeger, M. A., Fitzsimons, D. P., Prins, K. W. & Ervasti, J. M., Jul 2 2008, In : PLoS One. 3, 7, e2604.

Research output: Contribution to journalArticle

dystrophin
Dystrophin
Muscle
glycoproteins
Glycoproteins
18 Citations (Scopus)

Skeletal muscle-specific ablation of γcyto-actin does not exacerbate the mdx phenotype

Prins, K. W., Lowe, D. A. & Ervasti, J. M., Jun 11 2008, In : PloS one. 3, 6, e2419.

Research output: Contribution to journalArticle

dystrophin
Dystrophin
Ablation
actin
Muscle