Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research Interest Keywords
- Right ventricular dysfunction
- Microtubules
- Metabolism
- Junctophilin-2
- T-tubules
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Collaborations and top research areas from the last five years
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Junctophilin-2 Interacts with Mitofusin-2 To Regulate RV Mitochondrial
Prins, K. W. (PI)
BAYER HEALTHCARE PHARMACEUTICALS
1/30/23 → 1/29/25
Project: Research project
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Year 2 RPPR Multi-scale Investigation of Sex Differences in Right Ventricular Function via Estrogen-Microtubule Interactions
Prins, K. W. (PI) & Gardner, M. K. (CoI)
NATIONAL INSTITUTES OF HEALTH (NIH)
5/1/22 → 4/30/27
Project: Research project
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GP130 Antagonism in Porcine RV Pressure Overload
Prins, K. W. (PI), Kazmirczak, F. (CoI), Martin, C. M. (CoI) & Yannopoulos, D. (CoI)
NIH NAT'L HEART, LUNG, AND BLOOD INSTITU
5/1/22 → 4/30/26
Project: Research project
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Multi-scale Investigation of Sex Differences in Right Ventricular Function via Estrogen-Microtubule Interactions
Prins, K. W. (PI)
NIH NAT'L HEART, LUNG, AND BLOOD INSTITU
5/1/22 → 4/30/27
Project: Research project
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WNK Kinase Promotes RV Glucotoxicity in PAH
Prins, K. W. (PI)
7/1/21 → 6/30/23
Project: Research project
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Clinical determinants and prognostic implications of right ventricular dysfunction in pulmonary hypertension caused by chronic lung disease
Prins, K. W., Rose, L., Archer, S. L., Pritzker, M. R., Weir, E. K., Olson, M. D. & Thenappan, T., Jan 1 2019, In: Journal of the American Heart Association. 8, 2, e011464.Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
Disproportionate right ventricular dysfunction and poor survival in group 3 pulmonary hypertension
Prins, K. W., Rose, L., Archer, S. L., Pritzker, M. R., Weir, E. K., Kazmirczak, F., Misialek, J. R. & Thenappan, T., Jun 1 2018, In: American journal of respiratory and critical care medicine. 197, 11, p. 1496-1499 4 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
Colchicine depolymerizes microtubules, increases junctophilin-2, and improves right ventricular function in experimental pulmonary arterial hypertension
Prins, K. W., Tian, L., Wu, D., Thenappan, T., Metzger, J. M. & Archer, S. L., Jun 1 2017, In: Journal of the American Heart Association. 6, 6, e006195.Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
Interleukin-6 is independently associated with right ventricular function in pulmonary arterial hypertension
Prins, K. W., Archer, S. L., Pritzker, M., Rose, L., Weir, E. K., Sharma, A. & Thenappan, T., Mar 2018, In: Journal of Heart and Lung Transplantation. 37, 3, p. 376-384 9 p.Research output: Contribution to journal › Article › peer-review
Open Access72 Scopus citations -
Microtubule-Mediated Misregulation of Junctophilin-2 Underlies T-Tubule Disruptions and Calcium Mishandling in mdx Mice
Prins, K. W., Asp, M. L., Zhang, H., Wang, W. & Metzger, J. M., Apr 1 2016, In: JACC: Basic to Translational Science. 1, 3, p. 122-130 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access31 Scopus citations