1987 …2017
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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

  • 3 Similar Profiles
NAD Medicine & Life Sciences
Nucleosides Medicine & Life Sciences
Thymidylate Synthase Chemical Compounds
Enzymes Medicine & Life Sciences
Inosine Monophosphate Medicine & Life Sciences
Conformations Chemical Compounds
Oxidoreductases Medicine & Life Sciences
Deoxyuridine Chemical Compounds

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Research Output 1987 2017

2 Citations

Inhibition of calcineurin or IMP dehydrogenase exerts moderate to potent antiviral activity against norovirus replication

Dang, W., Yin, Y., Wang, Y., Wang, W., Su, J., Sprengers, D., Van Der Laan, L. J. W., Felczak, K., Pankiewicz, K. W., Chang, K. O., Koopmans, M. P. G., Metselaar, H. J., Peppelenbosch, M. P. & Pana, Q., Nov 1 2017, In : Antimicrobial agents and chemotherapy. 61, 11, e01095-17.

Research output: Contribution to journalArticle

IMP Dehydrogenase
Norovirus
Calcineurin
Antiviral Agents
Mycophenolic Acid
9 Citations

Cross talk between nucleotide synthesis pathways with cellular immunity in constraining hepatitis e virus replication

Wang, Y., Wang, W., Xu, L., Zhou, X., Shokrollahi, E., Felczak, K. Z., Van Der Laan, L. J. W., Pankiewicz, K. W., Sprengers, D., Raat, N. J. H., Metselaar, H. J., Peppelenbosch, M. P. & Pan, Q., May 1 2016, In : Antimicrobial agents and chemotherapy. 60, 5, p. 2834-2848 15 p.

Research output: Contribution to journalArticle

Hepatitis E virus
Hepatitis Viruses
Virus Replication
Cellular Immunity
Nucleotides
9 Citations

Mycophenolic acid potently inhibits rotavirus infection with a high barrier to resistance development

Yin, Y., Wang, Y., Dang, W., Xu, L., Su, J., Zhou, X., Wang, W., Felczak, K., van der Laan, L. J. W., Pankiewicz, K. W., van der Eijk, A. A., Bijvelds, M., Sprengers, D., de Jonge, H., Koopmans, M. P. G., Metselaar, H. J., Peppelenbosch, M. P. & Pan, Q., Sep 1 2016, In : Antiviral Research. 133, p. 41-49 9 p.

Research output: Contribution to journalArticle

Mycophenolic Acid
Rotavirus Infections
Immunosuppressive Agents
Rotavirus
Organoids
5 Citations

From ribavirin to NAD analogues and back to ribavirin in search for anticancer agents

Pankiewicz, K. W. & Felczak, K., Oct 1 2015, In : Heterocyclic Communications. 21, 5, p. 249-257 9 p.

Research output: Contribution to journalReview article

tiazofurin
Ribavirin
Inosine Monophosphate
Antineoplastic Agents
NAD
13 Citations

Nicotinamide Adenine Dinucleotide based therapeutics, update

Pankiewicz, K. W., Petrelli, R., Singh, R. & Felczak, K., Jan 1 2015, In : Current Medicinal Chemistry. 22, 34, p. 3991-4028 38 p.

Research output: Contribution to journalArticle

NAD
IMP Dehydrogenase
Enzymes
Therapeutics
Mycophenolic Acid