Kirsten Nielsen

1993 …2023
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Cryptococcus neoformans Medicine & Life Sciences
Virulence Medicine & Life Sciences
Cryptococcal Meningitis Medicine & Life Sciences
Cryptococcus Medicine & Life Sciences
Saturn Medicine & Life Sciences
Fungal Drug Resistance Medicine & Life Sciences
Cryptococcosis Medicine & Life Sciences
HIV Medicine & Life Sciences

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Projects 2008 2023

Pharmaceutical Preparations
T-2307
Cryptococcus
Cryptococcosis
Capacity Building
Cryptococcosis
Research
Saturn
Cryptococcus

Research Output 1993 2019

4 Citations (Scopus)

Adjunctive sertraline for HIV-associated cryptococcal meningitis: a randomised, placebo-controlled, double-blind phase 3 trial

ASTRO-CM Team, Aug 2019, In : The Lancet Infectious Diseases. 19, 8, p. 843-851 9 p.

Research output: Contribution to journalArticle

Cryptococcal Meningitis
Sertraline
Placebos
HIV
Amphotericin B

A titanic drug resistance threat in Cryptococcus neoformans

Zafar, H., Altamirano, S., Ballou, E. R. & Nielsen, K., Dec 2019, In : Current Opinion in Microbiology. 52, p. 158-164 7 p.

Research output: Contribution to journalReview article

Cryptococcus neoformans
Drug Resistance
Cryptococcal Meningitis
Cryptococcus
Ploidies
6 Citations (Scopus)

HIV-Associated cryptococcal meningitis occurring at relatively higher CD4 counts

Tugume, L., Rhein, J., Hullsiek, K. H., Mpoza, E., Kiggundu, R., Ssebambulidde, K., Schutz, C., Taseera, K., Williams, D. A., Abassi, M., Muzoora, C., Musubire, A. K., Meintjes, G., Meya, D. B., Boulware, D. R., Nabeta, H. W., Ndyetukira, J. F., Ahimbisibwe, C., Kugonza, F., Namuju, C. & 28 others, Sadiq, A., Namudde, A., Mwesigye, J., Kandole, T. K., Kwizera, R., Kirumira, P., Okirwoth, M., Akampurira, A., Luggya, T., Kaboggoza, J., Laker, E., Atwine, L., Muganzi, D., Evans, E. E., Bridge, S. C., Velamakanni, S. S., Rajasingham, R., Pastick, K., Stadelman, A., Flynn, A., Fujita, A. W., Mukaremera, L., Lofgren, S. M., Morawski, B. M., Bangdiwala, A., Nielsen, K., Bohjanen, P. R. & Kambugu, A., Feb 23 2019, In : Journal of Infectious Diseases. 219, 6, p. 877-883 7 p.

Research output: Contribution to journalArticle

Cryptococcal Meningitis
CD4 Lymphocyte Count
HIV
Cerebrospinal Fluid
Interleukin-13
1 Citation (Scopus)

Identification of pathogen genomic differences that impact human immune response and disease during cryptococcus neoformans infection

Gerstein, A. C., Jackson, K. M., McDonald, T. R., Wang, Y., Lueck, B. D., Bohjanen, S., Smith, K. D., Akampurira, A., Meya, D. B., Xue, C., Boulware, D. R. & Nielsen, K., Jan 1 2019, In : mBio. 10, 4, e01440-19.

Research output: Contribution to journalArticle

Open Access
Cryptococcus neoformans
Immune System Diseases
Cryptococcus
Infection
Gene Deletion
3 Citations (Scopus)

The mouse inhalation model of Cryptococcus neoformans infection recapitulates strain virulence in humans and shows that closely related strains can possess differential virulence

Mukaremera, L., McDonald, T. R., Nielsen, J. N., Molenaar, C. J., Akampurira, A., Schutz, C., Taseera, K., Muzoora, C., Meintjes, G., Meya, D. B., Boulware, D. R. & Nielsen, K., May 1 2019, In : Infection and immunity. 87, 5, e00046-19.

Research output: Contribution to journalArticle

Cryptococcus neoformans
Inhalation
Virulence
Infection
Mortality