20012020

Research activity per year

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Personal profile

Research interests

Fungal infections affect billions of people every year, often causing lethal disease in immunocompromised individuals. Of particular concern are invasive fungal infections, estimated to kill one and a half million people annually. Cryptococcus neoformans infections cause almost half of all deaths due to fungal infection. Even with access to the best available antifungals, Cn mortality rates of 20-40% remain unacceptably high. Although natural immunity to fungal infection is quite efficient in immune replete humans, disease in immune deficient individuals is often a complex interaction between failure to control fungal replication and an inappropriate immune response. My research program focuses on understanding how Cryptococcus changes its morphology and interacts with the immune system to cause disease, with the goal of developing better treatment strategies that improve patient survival.

Expertise related to UN SDGs

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

PhD, North Carolina, State Univerisity

Award Date: Jun 1 2007

Research Interest Keywords

  • Microbiology
  • Infectious diseases
  • Mycology
  • fungal morphogenesis
  • Cell biology
  • Molecular biology
  • Genetics
  • Genomics
  • pathogenesis of fungal infections
  • host-pathogen interactions

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The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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