Projects per year
Personal profile
Research interests
The Lang Lab is focused on understanding how core biological processes, such as DNA replication, transcription, and translation, are affected during host-pathogen interactions. We use a multi-disciplinary approach including genetics, biochemistry, cell biology, proteomics, and genomics.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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Collaborations and top research areas from the last five years
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Projects
- 1 Finished
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Reducing resistance: determining underlying mechanisms d
Lang, K. S. (PI) & Johnson, T. (CoI)
USDA Nat'l Inst. of Food & Agriculture
9/1/13 → 8/31/15
Project: Research project
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Direct visualization of transcription-replication conflicts reveals post-replicative DNA:RNA hybrids
Stoy, H., Zwicky, K., Kuster, D., Lang, K. S., Krietsch, J., Crossley, M. P., Schmid, J. A., Cimprich, K. A., Merrikh, H. & Lopes, M., Mar 2023, In: Nature Structural and Molecular Biology. 30, 3, p. 348-359 12 p.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
Development of Fluoroquinolone Resistance through Antibiotic Tolerance in Campylobacter jejuni
Park, M., Kim, J., Feinstein, J., Lang, K. S., Ryu, S. & Jeon, B., Sep 2022, In: Microbiology Spectrum. 10, 5Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Topological stress is responsible for the detrimental outcomes of head-on replication-transcription conflicts
Lang, K. S. & Merrikh, H., Mar 2 2021, In: Cell reports. 34, 9, 108797.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
Crystal structure of a membrane-bound O-acyltransferase
Ma, D., Wang, Z., Merrikh, C. N., Lang, K. S., Lu, P., Li, X., Merrikh, H., Rao, Z. & Xu, W., Oct 11 2018, In: Nature. 562, 7726, p. 286-290 5 p.Research output: Contribution to journal › Article › peer-review
Open Access79 Scopus citations -
The Clash of Macromolecular Titans: Replication-Transcription Conflicts in Bacteria
Lang, K. S. & Merrikh, H., Sep 8 2018, In: Annual Review of Microbiology. 72, p. 71-88 18 p.Research output: Contribution to journal › Review article › peer-review
57 Scopus citations