Keyphrases
Doxorubicin
100%
Perfluorohexanoic Acid (PFHxA)
54%
Mitochondrial Permeability Transition
41%
Mitochondria
34%
Mitochondrial Dysfunction
30%
Rodents
25%
Cyclosporine
24%
Mitochondrial Function
22%
Mitochondrial DNA
21%
Mitochondrial Respiration
21%
Dose Effect
20%
Adriamycin
20%
Mitochondrial Bioenergetics
20%
Mitochondrial Toxicity
20%
Lung
17%
Toxicity Mechanism
15%
Cardiomyopathy
14%
Redox Cycling
14%
Sprague-Dawley Rats
14%
Angiotensin I
13%
Liver
13%
Doxorubicin Treatments
13%
Nucleoside Reverse Transcriptase Inhibitors
13%
H9c2 Cardiomyocytes
12%
Gene Expression
12%
Mitochondrial Biogenesis
11%
Cardiotoxicity
11%
Quinones
11%
Membrane Potential
11%
Myocytes
10%
Acid Activation
10%
Depolarization
10%
Metabolism
10%
Perfluoroalkyl Acids
10%
Brain Acetylcholinesterase
9%
Structure-activity Relationship
9%
Subchronic
9%
Doxorubicin-induced Cardiotoxicity
9%
Bile Acids
9%
Perfluorooctanoate
9%
N-acetylation
9%
Liver Mitochondria
9%
Cell Injury
9%
Age-related Differences
9%
Peroxisome Proliferation
9%
Cytotoxicity
9%
Mitochondrial Targeting
9%
Cell Killing
9%
Anthracyclines
8%
8-hydroxydeoxyguanosine (8-OHdG)
8%
Pharmacology, Toxicology and Pharmaceutical Science
Doxorubicin
99%
Perfluorooctanesulfonic Acid
30%
Perfluorooctanoic Acid
26%
Ciclosporin
24%
Mitochondrial DNA
21%
Mitochondrial Toxicity
20%
Cardiotoxicity
18%
Toxicology
18%
Peroxisome Proliferator Activated Receptor
18%
Myocardial Disease
16%
Sulfonamide
15%
Sprague Dawley Rat
13%
Cytotoxicity
13%
Acetic Acid Derivative
11%
Perfluorooctane
11%
Quantitative Structure-Activity Relationship
11%
Toxic Injury
10%
RNA Directed DNA Polymerase Inhibitor
9%
Carboxylate
9%
Bile Acid
9%
Antioxidant
9%
Menadione
9%
Cholinesterase Inhibitor
8%
Adenosine Triphosphate
8%
Chenodeoxycholic Acid
8%
Cell Nucleus Receptor
7%
Ethylene Glycol
7%
Glutathione
7%
Ursodeoxycholic Acid
7%
Tissue Injury
7%
Potassium Ion
7%
Naphthoquinone
7%
Toxicokinetics
7%
Nucleoside Analog
7%
Isotopes of Potassium
7%
Acetylcholinesterase
7%
Thyroid Hormone
7%
Thyroxine
6%
Cell Nucleus DNA
6%
Structure Activity Relationship
6%
Thiol
6%
Adenine Nucleotide Translocase
6%
Reactive Oxygen Metabolite
6%
Carvedilol
6%
Fatty Liver
6%
Receptor
6%
Zidovudine
6%
Malignant Neoplasm
6%
1,4 Naphthoquinone
6%
Transcription Factor Nrf2
5%
Biochemistry, Genetics and Molecular Biology
Doxorubicin
72%
Mitochondrion
34%
Mitochondrial Permeability
21%
Mitochondrial Disorder
18%
Angiotensin
18%
Bioenergy
17%
Ciclosporin
13%
Cardiac Muscle Cell
13%
Mitochondrial DNA
10%
Mitochondrial Respiration
10%
Serotonin
10%
Angiotensin-Converting Enzyme
10%
Oxidative Stress
9%
Morphology
9%
Anthracycline
8%
Enzyme Activity
8%
Metabolic Pathway
8%
Cytotoxicity
8%
Mitochondrial Biogenesis
7%
Bioenergetics
7%
Lipid Peroxidation
6%
Calcium Transport
6%
Oxidative Phosphorylation
6%
Cell Damage
6%
Perfluorooctanoic Acid
6%
Myoglobin
6%
Menadione
6%
Bile Acid
6%
Nucleoside
6%
Reverse Transcriptase
6%
Adenosine Triphosphate
6%
Programmed Cell Death
5%
Membrane Potential
5%
Cell Killing
5%
Cell Death
5%
Blood Plasma
5%
Sprague Dawley Rat
5%
Calcium Homeostasis
5%
Monoamine Oxidase A
5%
Monoamine Oxidase
5%