Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 9 Industry, Innovation, and Infrastructure
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Collaborations and top research areas from the last five years
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Off-the-Shelf Immune Effector Cells for Hematological Malignancies
Blazar, B. R. (PI), Felices, M. (PI), Luo, X. (PI), Miller, J. S. (PI), Osborn, M. J. (PI), Rao, J. S. (PI), Wagner, J. E. (PI), Bachanova, V. (CoI), Betts, B. (CoI), Brunstein, C. G. (CoI), Cichocki, F. M. (CoI), De For, T. E. (CoI), Eaton, A. (CoI), Hippen, K. L. (CoI), Maakaron, J. (CoI), McKenna, D. H. (CoI), Shanley, R. M. (CoI), Tolar, J. (CoI), Zaiken, M. C. (CoI), Dougherty, P. R. (Graduate Student), Peng, Y. (Graduate Student), Le, C. T. (Prior Principal Investigator), Braun, J. A. (Other Role), Cao, Q. (Other Role), Dasgupta, T. (Other Role), Hinderlie, P. (Other Role), Jin, D. D. (Other Role), Kennedy, P. (Other Role), Kile, Q. (Other Role), Kopp, B. (Other Role), Lenvik, T. R. (Other Role), Meyer, C. M. (Other Role), Phung, G. (Other Role), Ramesh, V. (Other Role), Sleeth, M. L. (Other Role), Soignier, Y. M. (Other Role) & Xia, L. H. (Other Role)
5/5/23 → 4/30/28
Project: Research project
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Project 2: Novel Approaches to Inducing Lung Allograft Tolerance in NHPs
Blazar, B. R. (PI) & Hippen, K. L. (CoI)
MASSACHUSETTS GENERAL HOSPITAL, NIH NATIONAL INST OF ALLERGY & INFECT DI
3/23/23 → 2/29/28
Project: Research project
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Minnesota Partnership for Biotechnology and Medical Genomics
Bartolomucci, A. (PI), Bischof, J. C. (PI), Blazar, B. R. (PI), Conelea, C. A. (PI), Crawford, P. (PI), Kang, P. B. (PI), Kumar, V. (PI), Lim, K. O. (PI), Marquard, J. L. (PI), McGovern, R. A. (PI), Melton-Meaux, G. B. (PI), Nahas, Z. (PI), Netoff, T. I. (PI), Opitz, A. (PI), Simon, G. J. (PI), Williams, J. W. (PI), van Berlo, J. (PI), Betts, B. (Co-Principal Investigator) & Hippen, K. L. (Co-Principal Investigator)
7/1/22 → 3/31/28
Project: Research project
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Enhancing Treg Therapeutic Efficacy in GVHD
Blazar, B. R. (PI), Griffin, T. J. (PI), Hippen, K. L. (PI) & Osborn, M. J. (CoI)
NIH NATL HEART, LUNG AND BLOOD INSTITU
5/15/22 → 3/31/27
Project: Research project
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Novel Biologic Therapies for BMT: Mechanistic Evaluation in Rhesus Macaques
Blazar, B. R. (PI) & Hippen, K. L. (CoI)
BOSTON CHILDREN'S HOSPITAL, NIH NATL HEART, LUNG AND BLOOD INSTITU
9/9/18 → 6/30/26
Project: Research project
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Acetyl-CoA carboxylase 1 inhibition increases Treg metabolism and graft-versus-host disease treatment efficacy via mitochondrial fusion
McDonald-Hyman, C., Aguilar, E. G., Compeer, E. B., Zaiken, M. C., Rhee, S. Y., Mohamed, F. A., Larson, J. H., Loschi, M. L., Lees, C., Thangavelu, G., Sleeth, M. L., Smith, K. D., Whangbo, J. S., Ritz, J., Sparwasser, T. D., O’Connor, R. S., Crawford, P. A., Rathmell, J. C., Kean, L. S. & Zeiser, R. & 3 others, , 2026, In: Journal of Clinical Investigation. 136, 1, p. 1-21 21 p., e182480.Research output: Contribution to journal › Article › peer-review
Open Access -
Acetyl-CoA carboxylase 1 inhibition increases Treg metabolism and graft-versus-host disease treatment efficacy via mitochondrial fusion
McDonald-Hyman, C., Aguilar, E. G., Compeer, E. B., Zaiken, M. C., Rhee, S. Y., Mohamed, F. A., Larson, J. H., Loschi, M. L., Lees, C., Thangavelu, G., Sleeth, M. L., Smith, K. D., Whangbo, J. S., Ritz, J., Sparwasser, T. D., O’Connor, R. S., Crawford, P. A., Rathmell, J. C., Kean, L. S. & Zeiser, R. & 3 others, , Dec 2025, In: Journal of Clinical Investigation. 135, 23, e182480.Research output: Contribution to journal › Article › peer-review
Open Access4 Link opens in a new tab Scopus citations -
A simple and efficient method for the robust expansion of human ILC2s to prevent acute GVHD
Bruce, D. W., Laurie, S. J., Xing, Y., Stefanski, H. E., Hippen, K. L., Wilkinson, A. D., Woodcock, M. G., Coghill, J. M., McKinnon, K. P., Blazar, B. R. & Serody, J. S., Oct 14 2025, In: Blood Advances. 9, 19, p. 4951-4962 12 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Deficiency of T follicular helper cell Tet3 DNA demethylation inhibits pathogenic IgG2c class switching and chronic GVHD
Zaiken, M. C., Jin, S., McDonald-Hyman, C. S., Hartigan, C. R., Sage, P. T., Hippen, K. L., Koehn, B. H., Panoskaltsis-Mortari, A., Riddle, M. J., Eide, C. R., Tolar, J., Hill, G. R., Luznik, L., Cutler, C. S., Ritz, J. R., Kean, L. S., Tsagaratou, A., Rao, A. & Blazar, B. R., Jun 12 2025, In: Blood. 145, 24, p. 2813-2827 15 p.Research output: Contribution to journal › Article › peer-review
4 Link opens in a new tab Scopus citations -
Inflammasome-resistant IPSC-derived myeloid-derived suppressor cells ameliorate xenogeneic graft-versus-host disease
Ma, L., Koehn, B., Zaiken, M., Hippen, K. L., Smith, K., Allred, J., Williams, R., Yao, K., Fink, J., Saha, A., Koop, B., Payne, N., Widelak, R., Panoskaltsis-Mortari, A., Riddle, M. J., Tolar, J., Eide, C., Xia, L., Witty, A. D. & Mehta, A. K. & 9 others, , Oct 23 2025, In: Blood. 146, 17, p. 2047-2062 16 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Scopus citations