Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Off-the-Shelf Immune Effector Cells for Hematological Malignancies
Wagner, J. E. (PI), Bachanova, V. (CoI), Betts, B. (CoI), Brunstein, C. G. (CoI), Cichocki, F. M. (CoI), De For, T. E. (CoI), Eaton, A. (CoI), Hippen, K. L. (CoI), Luo, X. (CoI), Maakaron, J. (CoI), McKenna, D. H. (CoI) & Tolar, J. (CoI)
NIH NATIONAL CANCER INSTITUTE (NCI)
5/5/23 → 4/30/28
Project: Research project
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Project 2: Novel Approaches to Inducing Lung Allograft Tolerance in NHPs
Blazar, B. R. (PI) & Hippen, K. L. (CoI)
MASSACHUSETTS GENERAL HOSPITAL, NIH Nat'l Inst of Allergy & Infect Dis
3/23/23 → 2/29/28
Project: Research project
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Enhancing Treg Therapeutic Efficacy in GVHD
Blazar, B. R. (PI), Griffin, T. J. (CoI), Hippen, K. L. (CoI) & Osborn, M. J. (CoI)
NIH NAT'L HEART, LUNG, AND BLOOD INSTITU
5/15/22 → 3/31/26
Project: Research project
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Novel Biologic Therapies for BMT: Mechanistic Evaluation in Rhesus Macaques
Blazar, B. R. (PI) & Hippen, K. L. (CoI)
BOSTON CHILDREN'S HOSPITAL, NIH NAT'L HEART, LUNG, AND BLOOD INSTITU
9/9/18 → 6/30/26
Project: Research project
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Orthogonal IL2 Receptor Transduced Regulatory T Cells for Clinical Application
Blazar, B. R. (PI) & Hippen, K. L. (CoI)
STANFORD UNIVERSITY, CALIFORNIA INST. FOR REGENERATIVE MED.
1/1/24 → 12/31/24
Project: Research project
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Deficiency of T follicular helper cell Tet3 DNA demethylation inhibits pathogenic IgG2c class switching and chronic GVHD
Zaiken, M. C., Jin, S., McDonald-Hyman, C. S., Hartigan, C. R., Sage, P. T., Hippen, K. L., Koehn, B. H., Panoskaltsis-Mortari, A., Riddle, M. J., Eide, C. R., Tolar, J., Hill, G. R., Luznik, L., Cutler, C. S., Ritz, J. R., Kean, L. S., Tsagaratou, A., Rao, A. & Blazar, B. R., 2025, (Accepted/In press) In: Blood.Research output: Contribution to journal › Article › peer-review
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Targeting cell-surface VISTA expression on allo-specific naïve T cells promotes tolerance
Koehn, B. H., Nowak, E. C., Skopelja-Gardner, S., Saha, A., Zaiken, M. C., Allred, J., Peng, Y., Davis, W. L., Le Mercier, I., Schwertner, N., Molloy, M. J., Rothstein, J., Carriere, C., Riddle, M. J., Eide, C. R., Tolar, J., Panoskaltsis-Mortari, A., Smith, K. D., Hippen, K. L. & Kim, T. K. & 2 others, , Apr 10 2025, In: Blood. 145, 15, p. 1687-1700 14 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Lactate supports Treg function and immune balance via MGAT1 effects on N-glycosylation in the mitochondria
Zhou, J., Gu, J., Qian, Q., Zhang, Y., Huang, T., Li, X., Liu, Z., Shao, Q., Liang, Y., Qiao, L., Xu, X., Chen, Q., Xu, Z., Li, Y., Gao, J., Pan, Y., Wang, Y., O'Connor, R., Hippen, K. L. & Lu, L. & 1 others, , Oct 15 2024, In: Journal of Clinical Investigation. 134, 20, e175897.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Overexpression of AMPKγ2 increases AMPK signaling to augment human T cell metabolism and function
Braverman, E. L., McQuaid, M. A., Schuler, H., Qin, M., Hani, S., Hippen, K., Monlish, D. A., Dobbs, A. K., Ramsey, M. J., Kemp, F., Wittmann, C., Ramgopal, A., Brown, H., Blazar, B. & Byersdorfer, C. A., Jan 2024, In: Journal of Biological Chemistry. 300, 1, 105488.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Regulatory T cells crosstalk with tumor cells and endothelium through lymphotoxin signaling
Piao, W., Wu, L., Xiong, Y., Zapas, G. C., Paluskievicz, C. M., Oakes, R. S., Pettit, S. M., Sleeth, M. L., Hippen, K. L., Schmitz, J., Ivanyi, P., Shetty, A. C., Song, Y., Kong, D., Lee, Y., Li, L., Shirkey, M. W., Kensiski, A., Alvi, A. & Ho, K. & 6 others, , Dec 2024, In: Nature communications. 15, 1, 10468.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations