Karunya K Kandimalla

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Alzheimer Disease Medicine & Life Sciences
Amyloid Plaques Medicine & Life Sciences
Amyloid Chemical Compounds
Blood-Brain Barrier Medicine & Life Sciences
Brain Medicine & Life Sciences
Cerebral Amyloid Angiopathy Medicine & Life Sciences
Amyloidogenic Proteins Medicine & Life Sciences
Melatonin Medicine & Life Sciences

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Projects 2013 2023

Cerebral Amyloid Angiopathy
Alzheimer Disease
Drug Delivery Systems
Drug Delivery Systems

Research Output 1998 2019

2 Citations (Scopus)

Amyloid-beta impairs insulin signaling by accelerating autophagy-lysosomal degradation of LRP-1 and IR-β in blood-brain barrier endothelial cells in vitro and in 3XTg-AD mice

Gali, C. C., Fanaee-Danesh, E., Zandl-Lang, M., Albrecher, N. M., Tam-Amersdorfer, C., Stracke, A., Sachdev, V., Reichmann, F., Sun, Y., Avdili, A., Reiter, M., Kratky, D., Holzer, P., Lass, A., Kandimalla, K. K. & Panzenboeck, U., Sep 2019, In : Molecular and Cellular Neuroscience. 99, 103390.

Research output: Contribution to journalArticle

Open Access
Lipoprotein Receptors
Insulin Receptor
Blood-Brain Barrier
2 Citations (Scopus)

Apolipoprotein A-I crosses the blood-brain barrier through clathrin-independent and cholesterol-mediated endocytosis

Zhou, A. L., Swaminathan, S. K., Curran, G. L., Poduslo, J. F., Lowe, V. J., Li, L. & Kandimalla, K. K., Jan 1 2019, In : Journal of Pharmacology and Experimental Therapeutics. 369, 3, p. 481-488 8 p.

Research output: Contribution to journalArticle

Apolipoprotein A-I
Blood-Brain Barrier
4 Citations (Scopus)

Cationic carrier peptide enhances cerebrovascular targeting of nanoparticles in Alzheimer's disease brain

Ahlschwede, K. M., Curran, G. L., Rosenberg, J. T., Grant, S. C., Sarkar, G., Jenkins, R. B., Ramakrishnan, S., Poduslo, J. F. & Kandimalla, K. K., Feb 1 2019, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 16, p. 258-266 9 p.

Research output: Contribution to journalArticle

Alzheimer Disease
1 Citation (Scopus)

Design, Development, and Characterization of Imiquimod-Loaded Chitosan Films for Topical Delivery

Layek, B., Rahman Nirzhor, S. S., Rathi, S., Kandimalla, K. K., Wiedmann, T. S. & Prabha, S., Feb 1 2019, In : AAPS PharmSciTech. 20, 2, 58.

Research output: Contribution to journalArticle

patient compliance
1 Citation (Scopus)

Development and validation of a sensitive LC-MS/MS method for the estimation of scopolamine in human serum

Swaminathan, S. K., Fisher, J., Brogden, N. K. & Kandimalla, K. K., Feb 5 2019, In : Journal of Pharmaceutical and Biomedical Analysis. 164, p. 41-46 6 p.

Research output: Contribution to journalArticle

Scopolamine Hydrobromide
formic acid
Motion Sickness