Karunya K Kandimalla

19982023
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Alzheimer Disease Medicine & Life Sciences
Amyloid Plaques Medicine & Life Sciences
Amyloid Chemical Compounds
Blood-Brain Barrier Medicine & Life Sciences
Brain Medicine & Life Sciences
Cerebral Amyloid Angiopathy Medicine & Life Sciences
Amyloidogenic Proteins Medicine & Life Sciences
Melatonin Medicine & Life Sciences

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Projects 2013 2023

Cerebral Amyloid Angiopathy
Alzheimer Disease
Peptides
Drug Delivery Systems
oxybutynin
Fentanyl
Drug Delivery Systems

Research Output 1998 2019

Amyloid-beta impairs insulin signaling by accelerating autophagy-lysosomal degradation of LRP-1 and IR-β in blood-brain barrier endothelial cells in vitro and in 3XTg-AD mice

Gali, C. C., Fanaee-Danesh, E., Zandl-Lang, M., Albrecher, N. M., Tam-Amersdorfer, C., Stracke, A., Sachdev, V., Reichmann, F., Sun, Y., Avdili, A., Reiter, M., Kratky, D., Holzer, P., Lass, A., Kandimalla, K. K. & Panzenboeck, U., Sep 1 2019, In : Molecular and Cellular Neuroscience. 99, 103390.

Research output: Contribution to journalArticle

Open Access
Lipoprotein Receptors
Insulin Receptor
Autophagy
Blood-Brain Barrier
Amyloid
2 Citations (Scopus)

Apolipoprotein A-I crosses the blood-brain barrier through clathrin-independent and cholesterol-mediated endocytosis

Zhou, A. L., Swaminathan, S. K., Curran, G. L., Poduslo, J. F., Lowe, V. J., Li, L. & Kandimalla, K. K., Jan 1 2019, In : Journal of Pharmacology and Experimental Therapeutics. 369, 3, p. 481-488 8 p.

Research output: Contribution to journalArticle

Clathrin
Apolipoprotein A-I
Endocytosis
Blood-Brain Barrier
Cholesterol
2 Citations (Scopus)

Cationic carrier peptide enhances cerebrovascular targeting of nanoparticles in Alzheimer's disease brain

Ahlschwede, K. M., Curran, G. L., Rosenberg, J. T., Grant, S. C., Sarkar, G., Jenkins, R. B., Ramakrishnan, S., Poduslo, J. F. & Kandimalla, K. K., Feb 1 2019, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 16, p. 258-266 9 p.

Research output: Contribution to journalArticle

Amyloid
Nanoparticles
Peptides
Brain
Alzheimer Disease
1 Citation (Scopus)

Design, Development, and Characterization of Imiquimod-Loaded Chitosan Films for Topical Delivery

Layek, B., Rahman Nirzhor, S. S., Rathi, S., Kandimalla, K. K., Wiedmann, T. S. & Prabha, S., Feb 1 2019, In : AAPS PharmSciTech. 20, 2, 58.

Research output: Contribution to journalArticle

imiquimod
Chitosan
cream
chitosan
patient compliance
1 Citation (Scopus)

Development and validation of a sensitive LC-MS/MS method for the estimation of scopolamine in human serum

Swaminathan, S. K., Fisher, J., Brogden, N. K. & Kandimalla, K. K., Feb 5 2019, In : Journal of Pharmaceutical and Biomedical Analysis. 164, p. 41-46 6 p.

Research output: Contribution to journalArticle

Scopolamine Hydrobromide
Assays
Serum
formic acid
Motion Sickness