Karen H Ashe

1984 …2020

Research output per year

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Research Output

1994

The Genetics and Transgenetics of Human Prion Disease

HSIAO, KAREN. K., May 1994, In : Annals of the New York Academy of Sciences. 724, 1, p. 241-245 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein

Telling, G. C., Scott, M., Hsiao, K. K., Foster, D., Yang, S. L., Torchia, M., Sidle, K. C. L., Collinge, J., Dearmond, S. J. & Prusiner, S. B., Oct 11 1994, In : Proceedings of the National Academy of Sciences of the United States of America. 91, 21, p. 9936-9940 5 p.

Research output: Contribution to journalArticle

245 Scopus citations
1992

Linkage of the Indiana kindred of gerstmann-sträussler-scheinker disease to the prion protein gene

Dlouhy, S. R., Hsiao, K., Farlow, M. R., Foroud, T., Conneally, P. M., Johnson, P., Prusiner, S. B., Hodes, M. E. & Ghetti, B., Apr 1992, In : Nature Genetics. 1, 1, p. 64-67 4 p.

Research output: Contribution to journalArticle

176 Scopus citations

Mutant prion proteins in gerstmann-sträussler-scheinker disease with neurofibrillary tangles

Hsiao, K., Dlouhy, S. R., Farlow, M. R., Cass, C., Da Costa, M., Conneally, P. M., Hodes, M. E., Ghetti, B. & Prusiner, S. B., Apr 1992, In : Nature Genetics. 1, 1, p. 68-71 4 p.

Research output: Contribution to journalArticle

204 Scopus citations
1991

A prion protein variant in a family with the telencephalic form of Gerstmann-Sträussler-Scheinker syndrome

Hsiao, K. K., Cass, C., Schellenberg, G. D., Bird, T., Devine-Gage, E., Wisniewski, H. & Prusiner, S. B., May 1991, In : Neurology. 41, 5, p. 681-684 4 p.

Research output: Contribution to journalArticle

134 Scopus citations

Genetics of prion infections

Carlson, G. A., Hsiao, K., Oesch, B., Westaway, D. & Prusiner, S. B., Feb 1991, In : Trends in Genetics. 7, 2, p. 61-65 5 p.

Research output: Contribution to journalReview article

17 Scopus citations

Molecular genetics and transgenic model of Gertsmann-Straussler-Scheinker disease

Hsiao, K. & Prusiner, S. B., Jan 1 1991, In : Alzheimer disease and associated disorders. 5, 3, p. 155-162 8 p.

Research output: Contribution to journalReview article

11 Scopus citations

Mutation of the prion protein in libyan jews with creutzfeldt–jakob disease

Hsiao, K., Meiner, Z., Kahana, E., Cass, C., Kahana, I., Avrahami, D., Scarlato, G., Abramsky, O., Prusiner, S. B. & Gabizon, R., Apr 18 1991, In : New England Journal of Medicine. 324, 16, p. 1091-1097 7 p.

Research output: Contribution to journalArticle

211 Scopus citations

Regulation and genetic control of brain amyloid

Gajdusek, D. C., Beyreuther, K., Brown, P., Cork, L. C., Cunningham, D. D., Frangione, B., Gibbs, C. J., Goldfarb, L. G., Goldgaber, D., Hsiao, K. K., Koo, E. H., Martin, L. J., Masters, C. L., Odenwald, W. F., Price, D. L., Prusiner, S. B., Ruddle, F. H., Safar, J., Scangos, G., Schmechel, D. E. & 9 others, Shashikant, C. S., Shlichta, P. J., Sisodia, S. S., Trapp, B. D., Unterbeck, A., Van Nostrand, W. E., Violette, S. M., Walker, L. C. & Wirak, D., 1991, In : Brain Research Reviews. 16, 1, p. 83-114 32 p.

Research output: Contribution to journalArticle

13 Scopus citations

Spontaneous neurodegeneration in transgenic mice with prion protein codon 101 proline→leucine substitution

Hsiao, K., Scott, M., Foster, D., DeArmond, S. J., Groth, D., Serban, H. & Prusiner, S. B., Jan 1 1991, In : Annals of the New York Academy of Sciences. 640, p. 166-170 5 p.

Research output: Contribution to journalArticle

16 Scopus citations
1990

Inherited human prion diseases

Hsiao, K. & Prusiner, S. B., Dec 1990, In : Neurology. 40, 12, p. 1820-1827 8 p.

Research output: Contribution to journalArticle

140 Scopus citations

Spontaneous neurodegeneration in transgenic mice with mutant prion protein

Hsiao, K. K., Scott, M., Foster, D., Groth, D. F., Dearmond, S. J. & Prusiner, S. B., Dec 14 1990, In : Science. 250, 4987, p. 1587-1590 4 p.

Research output: Contribution to journalArticle

440 Scopus citations
1989

INSERTION IN PRION PROTEIN GENE IN FAMILIAL CREUTZFELDT-IAKOB DISEASE

Owen, F., Lofthouse, R., Crow, T. J., Baker, H. F., Poulter, M., Collinge, J., Risby, D., Ridley, R. M., Hsiao, K. & Prusiner, S. B., Jan 7 1989, In : The Lancet. 333, 8628, p. 51-52 2 p.

Research output: Contribution to journalLetter

239 Scopus citations

Linkage of a prion protein missense variant to Gerstmann-Sträussler syndrome

Hsiao, K., Baker, H. F., Crow, T. J., Poulter, M., Owen, F., Terwilliger, J. D., Westaway, D., Ott, J. & Prusiner, S. B., Jan 1 1989, In : Nature. 338, 6213, p. 342-345 4 p.

Research output: Contribution to journalArticle

651 Scopus citations
1988

Prion protein gene expression in cultured cells

Scott, M. R. D., Butler, D. A., Bredesen, D. E., Wälchli, M., Hsiao, K. K. & Prusiner, S. B., Apr 1 1988, In : Protein Engineering, Design and Selection. 2, 1, p. 69-76 8 p.

Research output: Contribution to journalArticle

41 Scopus citations

Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins

Butler, D. A., Scott, M. R. D., Bockman, J. M., Borchelt, D. R., Taraboulos, A., Hsiao, K. K., Kingsbury, D. T. & Prusiner, S. B., 1988, In : Journal of virology. 62, 5, p. 1558-1564 7 p.

Research output: Contribution to journalArticle

Open Access
284 Scopus citations
1987

Scrapie prion protein contains a phosphatidylinositol glycolipid

Stahl, N., Borchelt, D. R., Hsiao, K. & Prusiner, S. B., Oct 23 1987, In : Cell. 51, 2, p. 229-240 12 p.

Research output: Contribution to journalArticle

843 Scopus citations
1984

A minute fraction of Syrian golden hamster retinal ganglion cells project bilaterally

Hsiao, K., Sachs, G. M. & Schneider, G. E., 1984, In : Journal of Neuroscience. 4, 2, p. 259-367 109 p.

Research output: Contribution to journalArticle

Open Access
25 Scopus citations
Open Access
35 Scopus citations