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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Targeting caspase-2 to repair synaptic function in tauopathies
Ashe, K. H. (PI)
ALZHEIMER'S DRUG DISCOVERY FOUNDATION
10/1/24 → 10/1/26
Project: Research project
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Structure and toxicity of a specific tau oligomer related to dementia
Liu, P. (PI), Ashe, K. H. (CoI) & Liao, D. (CoI)
9/1/24 → 7/31/27
Project: Research project
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Prodrugs of potent and selective protease inhibitors as tauopathy therapeutics
Ashe, K. H. (PI), Walters, M. A. (CoI) & Wong, H. L. (CoI)
MYRIEL, INC., NATIONAL INSTITUTES OF HEALTH (NIH)
9/20/23 → 8/31/25
Project: Research project
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Repairing synapses in neurodegenerative disorders by inhibiting caspase-2
Ashe, K. H. (PI)
MYRIEL, INC., THE LUCAS BROTHERS FOUNDATION
10/1/22 → 12/31/25
Project: Research project
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Repairing neurotransmission in Alzheimer's disease and related disorders by targeting caspase-2
Ashe, K. H. (PI) & Liao, D. (CoI)
ALZHEIMER'S DRUG DISCOVERY FOUNDATION
3/1/22 → 3/5/23
Project: Research project
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Aβ∗56 is a stable oligomer that impairs memory function in mice
Liu, P., Lapcinski, I. P., Hlynialuk, C. J. W., Steuer, E. L., Loude, T. J., Shapiro, S. L., Kemper, L. J. & Ashe, K. H., Mar 15 2024, In: iScience. 27, 3, 109239.Research output: Contribution to journal › Article › peer-review
Open Access -
Retraction Note: A specific amyloid-β protein assembly in the brain impairs memory (Nature, (2006), 440, 7082, (352-357), 10.1038/nature04533)
Lesné, S., Koh, M. T., Kotilinek, L., Kayed, R., Glabe, C. G., Yang, A., Gallagher, M. & Ashe, K. H., Jul 4 2024, In: Nature. 631, 8019, p. 240 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access1 Scopus citations -
Accumulation of pTau231 at the Postsynaptic Density in Early Alzheimer's Disease
Lilek, J., Ajroud, K., Feldman, A. Z., Krishnamachari, S., Ghourchian, S., Gefen, T., Spencer, C. L., Kawles, A., Mao, Q., Tranovich, J. F., Jack, C. R., Mesulam, M. M., Reichard, R. R., Zhang, H., Murray, M. E., Knopman, D., Dickson, D. W., Petersen, R. C., Smith, B. & Ashe, K. H. & 3 others, , 2023, In: Journal of Alzheimer's Disease. 92, 1, p. 241-260 20 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
An electrophilic fragment screening for the development of small molecules targeting caspase-2
Cuellar, M. E., Yang, M., Karavadhi, S., Zhang, Y. Q., Zhu, H., Sun, H., Shen, M., Hall, M. D., Patnaik, S., Ashe, K. H., Walters, M. A. & Pockes, S., Nov 5 2023, In: European Journal of Medicinal Chemistry. 259, 115632.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Targeting caspase-2 interactions with tau in Alzheimer's disease and related dementias
Pockes, S., Walters, M. A. & Ashe, K. H., Apr 2023, In: Translational Research. 254, p. 34-40 7 p.Research output: Contribution to journal › Review article › peer-review
Open Access4 Scopus citations