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Karen H Ashe

1984 …2023

Research output per year

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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

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Projects

Caspase-2 Probe Compounds

Ashe, K. H., Finzel, B. C. & Nelson, K.

NIH NAT'L INSTITUTE ON AGING (NIA)

2/15/19 → 11/30/23

Project: Research project

    • Targeting caspase-2 to repair synaptic transmission in tauopathy

    Ashe, K. H.

    VARIOUS SPONSORS - NON-FEDERAL

    10/1/18 → 9/30/20

    Project: Research project

    • Molecular endophenotypes of H1 and H2 MAPT haplotypes

    Ashe, K. H.

    National Institutes of Health

    8/15/18 → 4/30/20

    Project: Research project

    • Role of Tau Cleavage and Phosphorylation in Tauopathy

    Ashe, K. H.

    NIH NAT'L INSTITUTE ON AGING (NIA)

    8/15/18 → 3/31/23

    Project: Research project

    • Curing Alzheimer's Disease: A Proposal for the Lucas Brothers Foundation

    Ashe, K. H.

    THE LUCAS BROTHERS FOUNDATION

    6/1/17 → 5/31/20

    Project: Research project

    • Research Output

    A Cautionary Tale: Endogenous Biotinylated Proteins and Exogenously-Introduced Protein A Cause Antibody-Independent Artefacts in Western Blot Studies of Brain-Derived Proteins

    Grant, M. K. O., Shapiro, S. L., Ashe, K. H., Liu, P. & Zahs, K. R., Apr 18 2019, In : Biological Procedures Online. 21, 1, 6.

    Research output: Contribution to journal › Article

    Open Access

    • A soluble tau fragment generated by caspase-2 is associated with dementia in Lewy body disease

    Smith, B. R., Nelson, K. M., Kemper, L. J., Leinonen-Wright, K., Petersen, A., Keene, C. D. & Ashe, K. H., Jul 30 2019, In : Acta Neuropathologica Communications. 7, 1, 1 p.

    Research output: Contribution to journal › Article

    Open Access
    • 1 Scopus citations

    A soluble truncated tau species related to cognitive dysfunction and caspase-2 is elevated in the brain of Huntington's disease patients

    Liu, P., Smith, B. R., Huang, E. S., Mahesh, A., Vonsattel, J. P. G., Petersen, A. J., Gomez-Pastor, R. & Ashe, K. H., Jul 30 2019, In : Acta Neuropathologica Communications. 7, 1, 1 p.

    Research output: Contribution to journal › Article

    Open Access
    • 2 Scopus citations

    Factors other than hTau overexpression that contribute to tauopathy-like phenotype in rTg4510 mice

    Gamache, J., Benzow, K., Forster, C., Kemper, L., Hlynialuk, C., Furrow, E., Ashe, K. H. & Koob, M. D., Dec 1 2019, In : Nature communications. 10, 1, 2479.

    Research output: Contribution to journal › Article

    Open Access
    • 5 Scopus citations

    Human cerebrospinal fluid 6E10- immunoreactive protein species contain amyloid precursor protein fragments

    Grant, M. K. O., Handoko, M., Rozga, M., Brinkmalm, G., Portelius, E., Blennow, K., Ashe, K. H., Zahs, K. R. & Liu, P., Feb 2019, In : PloS one. 14, 2, e0212815.

    Research output: Contribution to journal › Article

    Open Access