Karen H Ashe

1984 …2023
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Alzheimer Disease Medicine & Life Sciences
Transgenic Mice Medicine & Life Sciences
Amyloid beta-Protein Precursor Medicine & Life Sciences
Amyloid Medicine & Life Sciences
Amyloid Plaques Medicine & Life Sciences
Memory Disorders Medicine & Life Sciences
Brain Medicine & Life Sciences
Transgenes Medicine & Life Sciences

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Projects 1994 2023

Caspase 2
Caspase 2
Tauopathies
Synaptic Transmission
Tauopathies
Phosphorylation

Research Output 1984 2019

Open Access
Staphylococcal Protein A
Artifacts
Brain
Western Blotting
Antibodies

A soluble tau fragment generated by caspase-2 is associated with dementia in Lewy body disease

Smith, B. R., Nelson, K. M., Kemper, L. J., Leinonen-Wright, K., Petersen, A., Keene, C. D. & Ashe, K. H., Jul 30 2019, In : Acta Neuropathologica Communications. 7, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Caspase 2
Lewy Body Disease
Dementia
Lewy Bodies
Parkinson Disease

A soluble truncated tau species related to cognitive dysfunction and caspase-2 is elevated in the brain of Huntington's disease patients

Liu, P., Smith, B. R., Huang, E. S., Mahesh, A., Vonsattel, J. P. G., Petersen, A. J., Gomez-Pastor, R. & Ashe, K. H., Jul 30 2019, In : Acta Neuropathologica Communications. 7, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Caspase 2
Huntington Disease
Brain Diseases
Neurodegenerative Diseases
Trinucleotide Repeat Expansion
1 Citation (Scopus)
Open Access
Tauopathies
phenotype
Trans-Activators
Tetracycline
Transgenes

Human cerebrospinal fluid 6E10- immunoreactive protein species contain amyloid precursor protein fragments

Grant, M. K. O., Handoko, M., Rozga, M., Brinkmalm, G., Portelius, E., Blennow, K., Ashe, K. H., Zahs, K. R. & Liu, P., Feb 1 2019, In : PloS one. 14, 2, e0212815.

Research output: Contribution to journalArticle

Open Access
Cerebrospinal fluid
Amyloid beta-Protein Precursor
cerebrospinal fluid
amyloid
Cerebrospinal Fluid