Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Elucidating the biophysics of pre-fibrillar, toxic tau oligomers: from amino acid motifs to neuronal dysfunction
Sachs, J. N., Ashe, K. H., Nelson, K. & Yuan, S.
NIH NAT'L INSTITUTE ON AGING (NIA)
9/30/21 → 5/31/23
Project: Research project
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Caspase-2 Probe Compounds
Ashe, K. H., Finzel, B. C. & Nelson, K.
NIH NAT'L INSTITUTE ON AGING (NIA)
2/15/19 → 11/30/23
Project: Research project
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Role of Tau Cleavage and Phosphorylation in Tauopathy
NIH NAT'L INSTITUTE ON AGING (NIA)
8/15/18 → 3/31/23
Project: Research project
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Curing Alzheimer's Disease: A Proposal for the Lucas Brothers Foundation
6/1/17 → 5/31/22
Project: Research project
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Targeting caspase-2 to repair synaptic transmission in tauopathy
VARIOUS SPONSORS - NON-FEDERAL
10/1/18 → 5/31/21
Project: Research project
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Structure-Based Design and Biological Evaluation of Novel Caspase-2 Inhibitors Based on the Peptide AcVDVAD-CHO and the Caspase-2-Mediated Tau Cleavage Sequence YKPVD314
Bresinsky, M., Strasser, J. M., Vallaster, B., Liu, P., McCue, B., Fuller, J., Hubmann, A., Singh, G., Nelson, K., Cuellar, M. E., Wilmot, C. M., Finzel, B. C., Ashe, K. H., Walters, M. A. & Pockes, S., Jan 14 2022, In: ACS Pharmacology and Translational Science. 5, 1, p. 20-40 21 p.Research output: Contribution to journal › Article › peer-review
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Lifelong chronic psychosocial stress induces a proteomic signature of Alzheimer's disease in wildtype mice
Lyons, C. E., Zhou, X., Razzoli, M., Chen, M., Xia, W., Ashe, K., Zhang, B. & Bartolomucci, A., Jun 22 2021, In: European Journal of Neuroscience.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
The molecular implications of a caspase-2-mediated site-specific tau cleavage in tauopathies
Liu, P. & Ashe, K. H., Sep 2021, In: Neural Regeneration Research. 16, 9, p. 1774-1775 2 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A soluble truncated tau species related to cognitive dysfunction is elevated in the brain of cognitively impaired human individuals
Liu, P., Smith, B. R., Montonye, M. L., Kemper, L. J., Leinonen-Wright, K., Nelson, K. M., Higgins, L. A., Guerrero, C. R., Markowski, T. W., Zhao, X., Petersen, A. J., Knopman, D. S., Petersen, R. C. & Ashe, K. H., Mar 2 2020, In: Scientific reports. 10, 1, 3869.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Author Correction: A soluble truncated tau species related to cognitive dysfunction is elevated in the brain of cognitively impaired human individuals
Liu, P., Smith, B. R., Montonye, M. L., Kemper, L. J., Leinonen-Wright, K., Nelson, K. M., Higgins, L. A., Guerrero, C. R., Markowski, T. W., Zhao, X., Petersen, A. J., Knopman, D. S., Petersen, R. C. & Ashe, K. H., May 12 2020, In: Scientific reports. 10, 1, 8077.Research output: Contribution to journal › Comment/debate › peer-review
Open Access