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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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Collaborations and top research areas from the last five years
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Identifying and preventing antigen specific T cells in diabetes
Fife, B. T. (PI), Farrar, M. A. (CoI) & Spanier, J. A. (CoI)
NIH NATIONAL INST OF ALLERGY & INFECT DI
6/22/21 → 5/31/26
Project: Research project
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Engineering CAR Tregs for type 1 diabetes
Fife, B. T. (PI) & Spanier, J. A. (CoI)
NIH NATIONAL INST OF ALLERGY & INFECT DI
9/24/21 → 8/31/23
Project: Research project
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A Novel Method of Detecting Diabetes Specific CD4+TCells
Spanier, J. A. (PI)
7/1/14 → 6/30/17
Project: Research project
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CAR Treg cells mediate linked suppression and infectious tolerance in islet transplantation in mice
Wardell, C. M., Fung, V. C. W., Chen, E., Haque, M., Tan, D. F. H., Leca, M., Gillies, J., Spanier, J. A., Mojibian, M., Fife, B. T. & Levings, M. K., Aug 20 2025, In: Science Translational Medicine. 17, 812, eadp6519.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
CD4+ T cells reactive to a hybrid peptide from insulin-chromogranin A adopt a distinct effector fate and are pathogenic in autoimmune diabetes
Mitchell, J. S., Spanier, J. A., Dwyer, A. J., Knutson, T. P., Alkhatib, M. H., Qian, G., Weno, M. E., Chen, Y., Shaheen, Z. R., Tucker, C. G., Kangas, T. O., Morales, M. S., Silva, N., Kaisho, T., Farrar, M. A. & Fife, B. T., Oct 8 2024, In: Immunity. 57, 10, p. 2399-2415.e8Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Tregs with an MHC class II peptide-specific chimeric antigen receptor prevent autoimmune diabetes in mice
Spanier, J. A., Fung, V., Wardell, C. M., Alkhatib, M. H., Chen, Y., Swanson, L. A., Dwyer, A. J., Weno, M. E., Silva, N., Mitchell, J. S., Orban, P. C., Mojibian, M., Verchere, C. B., Fife, B. T. & Levings, M. K., Sep 15 2023, In: The Journal of clinical investigation. 133, 18Research output: Contribution to journal › Article › peer-review
Open Access50 Scopus citations -
Development of canine PD-1/PD-L1 specific monoclonal antibodies and amplification of canine T cell function
Choi, J. W., Withers, S. S., Chang, H., Spanier, J. A., De La Trinidad, V. L., Panesar, H., Fife, B. T., Sciammas, R., Sparger, E. E., Moore, P. F., Kent, M. S., Rebhun, R. B. & McSorley, S. J., Jul 2020, In: PloS one. 15, 7, e0235518.Research output: Contribution to journal › Article › peer-review
Open Access39 Scopus citations -
Vitamin D3-mediated resistance to a multiple sclerosis model disease depends on myeloid cell 1,25-dihydroxyvitamin D3 synthesis and correlates with increased CD4+ T cell CTLA-4 expression
Spanier, J. A., Nashold, F. E., Nelson, C. D., Praska, C. E. & Hayes, C. E., Jan 15 2020, In: Journal of Neuroimmunology. 338, 577105.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations