Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Identifying and preventing antigen specific T cells in diabetes
Fife, B. T. (PI), Farrar, M. A. (CoI) & Spanier, J. A. (CoI)
NIH Nat'l Inst of Allergy & Infect Dis
6/22/21 → 5/31/26
Project: Research project
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Engineering CAR Tregs for type 1 diabetes
Fife, B. T. (PI) & Spanier, J. A. (CoI)
NIH Nat'l Inst of Allergy & Infect Dis
9/24/21 → 8/31/23
Project: Research project
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A Novel Method of Detecting Diabetes Specific CD4+TCells
Spanier, J. A. (PI)
7/1/14 → 6/30/17
Project: Research project
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Tregs with an MHC class II peptide-specific chimeric antigen receptor prevent autoimmune diabetes in mice
Spanier, J. A., Fung, V., Wardell, C. M., Alkhatib, M. H., Chen, Y., Swanson, L. A., Dwyer, A. J., Weno, M. E., Silva, N., Mitchell, J. S., Orban, P. C., Mojibian, M., Verchere, C. B., Fife, B. T. & Levings, M. K., Sep 15 2023, In: The Journal of clinical investigation. 133, 18Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Development of canine PD-1/PD-L1 specific monoclonal antibodies and amplification of canine T cell function
Choi, J. W., Withers, S. S., Chang, H., Spanier, J. A., De La Trinidad, V. L., Panesar, H., Fife, B. T., Sciammas, R., Sparger, E. E., Moore, P. F., Kent, M. S., Rebhun, R. B. & McSorley, S. J., Jul 2020, In: PloS one. 15, 7, e0235518.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
Vitamin D3-mediated resistance to a multiple sclerosis model disease depends on myeloid cell 1,25-dihydroxyvitamin D3 synthesis and correlates with increased CD4+ T cell CTLA-4 expression
Spanier, J. A., Nashold, F. E., Nelson, C. D., Praska, C. E. & Hayes, C. E., Jan 15 2020, In: Journal of Neuroimmunology. 338, 577105.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
Fresh ideas, foundational experiments: Immunology and diabetes
Spanier, J. A., Tse, H. M., Horwitz, M. S. & Fife, B. T., 2019, In: Frontiers in Endocrinology. 10, MAY, 315.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Programmed death-1 restrains the germinal center in type 1 diabetes
Martinov, T., Swanson, L. A., Breed, E. R., Tucker, C. G., Dwyer, A. J., Johnson, J. K., Mitchell, J. S., Sahli, N. L., Wilson, J. C., Singh, L. M., Hogquist, K. A., Spanier, J. A. & Fife, B. T., Aug 15 2019, In: Journal of Immunology. 203, 4, p. 844-852 9 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations