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Justin A Spanier

20062020
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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

  • 24 Similar Profiles
T-Lymphocytes Medicine & Life Sciences
Multiple Sclerosis Medicine & Life Sciences
Cholecalciferol Medicine & Life Sciences
Type 1 Diabetes Mellitus Medicine & Life Sciences
Autoimmune Experimental Encephalomyelitis Medicine & Life Sciences
Autoimmunity Medicine & Life Sciences
Vitamin D Medicine & Life Sciences
Calcitriol Medicine & Life Sciences

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Projects 2014 2017

A Novel Method of Detecting Diabetes Specific CD4+TCells

Spanier, J. A.

Juvenile Diabetes Research Foundation

7/1/14 → 6/30/17

Project: Research project

Research Output 2006 2020

Vitamin D3-mediated resistance to a multiple sclerosis model disease depends on myeloid cell 1,25-dihydroxyvitamin D3 synthesis and correlates with increased CD4+ T cell CTLA-4 expression

Spanier, J. A., Nashold, F. E., Nelson, C. D., Praska, C. E. & Hayes, C. E., Jan 15 2020, In : Journal of Neuroimmunology. 338, 577105.

Research output: Contribution to journal › Article

Calcitriol
Cholecalciferol
Myeloid Cells
Multiple Sclerosis
Central Nervous System

Editorial: Fresh ideas, foundational experiments: Immunology and diabetes

Spanier, J. A., Tse, H. M., Horwitz, M. S. & Fife, B. T., Jan 1 2019, In : Frontiers in Endocrinology. 10, MAY, 315.

Research output: Contribution to journal › Editorial

Open Access
Islets of Langerhans Transplantation
Allergy and Immunology
Autoimmunity
Type 1 Diabetes Mellitus
Type 2 Diabetes Mellitus
1 Citation (Scopus)

Programmed death-1 restrains the germinal center in type 1 diabetes

Martinov, T., Swanson, L. A., Breed, E. R., Tucker, C. G., Dwyer, A. J., Johnson, J. K., Mitchell, J. S., Sahli, N. L., Wilson, J. C., Singh, L. M., Hogquist, K. A., Spanier, J. A. & Fife, B. T., Aug 15 2019, In : Journal of Immunology. 203, 4, p. 844-852 9 p.

Research output: Contribution to journal › Article

Germinal Center
Type 1 Diabetes Mellitus
Autoimmunity
Insulin
B-Lymphocytes
12 Citations (Scopus)

Thymic regulatory T cells arise via two distinct developmental programs

Owen, D. L., Mahmud, S., Sjaastad, L. E., Williams, J. B., Spanier, J. A., Simeonov, D. R., Ruscher, R., Huang, W., Proekt, I., Miller, C. N., Hekim, C., Jeschke, J. C., Aggarwal, P., Broeckel, U., LaRue, R. S., Henzler, C. M., Alegre, M. L., Anderson, M. S., August, A., Marson, A. & 3 others, Zheng, Y., Williams, C. B. & Farrar, M. A., Feb 1 2019, In : Nature immunology. 20, 2, p. 195-205 11 p.

Research output: Contribution to journal › Article

Regulatory T-Lymphocytes
Autoantigens
Stem Cells
T-Cell Antigen Receptor
Transcriptome

1,25-Dihydroxyvitamin D3 increases the methionine cycle, CD4+ T cell DNA methylation and Helios+Foxp3+ T regulatory cells to reverse autoimmune neurodegenerative disease

Moore, J. R., Hubler, S. L., Nelson, C. D., Nashold, F. E., Spanier, J. A. & Hayes, C. E., Nov 15 2018, In : Journal of Neuroimmunology. 324, p. 100-114 15 p.

Research output: Contribution to journal › Article

Calcitriol
Homocysteine
Regulatory T-Lymphocytes
DNA Methylation
Neurodegenerative Diseases