Projects per year
Personal profile
Research interests
I am an assistant professor in the Department of Pediatrics and a pediatric neuropsychologist. My research focuses on the natural histories and treatment outcomes of rare diseases involving the central nervous system, particularly lysosomal storage disorders with emphasis on the mucopolysaccharidoses. As part of this research I characterize unique neurocognitive profiles and progression of various neurodegenerative disorders, as well as quantify treatment outcomes and their correlates. In particular, my MPS research has examined longitudinal associations of cognitive deficits with abnormalities in biomarkers and brain structure.
A complete list of published work is available here:
https://www.ncbi.nlm.nih.gov/pubmed/?term=Julie+Eisengart
Keywords
- lysosomal storage disorders
- mucopolysaccharidosis
- adrenoleukodystrophy
- neurocognitive endpoints
- neurocognitive decline
- IQ and developmental quotient
- biomarkers
Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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Mucopolysaccharidosis I
Medicine & Life Sciences
Adrenoleukodystrophy
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Medicine & Life Sciences
Cell Transplantation
Medicine & Life Sciences
Corpus Callosum
Medicine & Life Sciences
Hematopoietic Stem Cell Transplantation
Medicine & Life Sciences
Transplants
Medicine & Life Sciences
Mucopolysaccharidosis II
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2017 2021
Biomarker correlates of neurocognitive outcomes in the cerebrospinal fluid in MPS I
2/1/19 → 1/31/20
Project: Research project
Cerebrospinal Fluid
Biomarkers
An Open-Label, Single-Arm, Multicenter Study of Intracerebral Administration of Adeno-Associated Viral Vectors Serotype rh10 Carrying the Human N-sulfoglucosamine sulfohydrolase(SGSH) cDNA for the Treatment ofMucopolysaccharidosis Type IIIA
Whitley, C. B., Belani, K. G. & Eisengart, J.
1/25/19 → 2/28/21
Project: Research project
Mucopolysaccharidosis III
Multicenter Studies
Complementary DNA
Serogroup
N-sulfoglucosamine sulfohydrolase
Clinical signs and biomarkers in the early natural history of attenuated MPS I
9/1/18 → 1/15/19
Project: Research project
Biomarkers
A Feasibility Study for Development of a Behavioral Rati
SHIRE HUMAN GENETIC THERAPIES, INC.
9/21/17 → 6/30/19
Project: Research project
Feasibility Studies
Behavior Rating Scale
Research Output 2006 2019
- 15 Article
Attention and corpus callosum volumes in individuals with mucopolysaccharidosis type I
King, K. E., Rudser, K., Nestrasil, I., Kovac, V., Delaney, K. A., Wozniak, J. R., Mueller, B. A., Lim, K. O., Eisengart, J., Mamak, E. G., Raiman, J., Ali, N., Cagle, S., Harmatz, P., Whitley, C. B. & Shapiro, E. G., May 14 2019, In : Neurology. 92, 20, p. e2321-e2328Research output: Contribution to journal › Article
Mucopolysaccharidosis I
Corpus Callosum
Cell Transplantation
Research
Intrathecal enzyme replacement for Hurler syndrome: biomarker association with neurocognitive outcomes
Eisengart, J., Pierpont, R., Kaizer, A. M., Rudser, K., King, K. E., Pasquali, M., Polgreen, L. E., Dickson, P. I., Le, S. Q., Miller, W. P., Tolar, J., Orchard, P. J. & Lund, T. C., Jan 1 2019, In : Genetics in Medicine.Research output: Contribution to journal › Article
Open Access
Mucopolysaccharidosis I
Enzyme Replacement Therapy
Biomarkers
Cerebrospinal Fluid
Enzymes
3
Citations
(Scopus)
Mucopolysaccharidosis I
Benchmarking
Cell Transplantation
Neurodegenerative Diseases
Newborn Infant
6
Citations
(Scopus)
Open Access
Mucopolysaccharidosis I
Enzyme Replacement Therapy
Cell Transplantation
Therapeutics
Newborn Infant
6
Citations
(Scopus)
Long-term cognitive and somatic outcomes of enzyme replacement therapy in untransplanted Hurler syndrome
Eisengart, J., Jarnes, J., Ahmed, A., Nestrasil, I., Ziegler, R. S., Delaney, K., Shapiro, E. G. & Whitley, C. B., Dec 1 2017, In : Molecular Genetics and Metabolism Reports. 13, p. 64-68 5 p.Research output: Contribution to journal › Article
Open Access
Mucopolysaccharidosis I
Enzyme Replacement Therapy
Cell Transplantation
Central Nervous System Diseases
Bilateral Hearing Loss