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Blood outgrowth endothelial cells from Hereditary Haemorrhagic Telangiectasia patients reveal abnormalities compatible with vascular lesions

Fernandez-L, A., Sanz-Rodriguez, F., Zarrabeitia, R., Pérez-Molino, A., Hebbel, R. P., Nguyen, J., Bernabéu, C. & Botella, L. M., Nov 1 2005, In : Cardiovascular Research. 68, 2, p. 235-248 14 p.

Research output: Contribution to journalArticle

61 Scopus citations

Cannabinoid receptor-specific mechanisms to alleviate pain in sickle cell anemia via inhibition of mast cell activation and neurogenic inflammation

Vincent, L., Vang, D., Nguyen, J., Benson, B., Lei, J. & Gupta, K., Apr 30 2016, In : Haematologica. 101, 5, p. 566-577 12 p.

Research output: Contribution to journalArticle

23 Scopus citations
24 Scopus citations
6 Scopus citations

CYP3A4 mediates growth of estrogen receptor-positive breast cancer cells in part by inducing nuclear translocation of phospho-Stat3 through biosynthesis of (±)-14,15-epoxyeicosatrienoic acid (EET)

Mitra, R., Guo, Z., Milani, M., Mesaros, C., Rodriguez, M., Nguyen, J., Luo, X., Clarke, D., Lamba, J., Schuetz, E., Donner, D. B., Puli, N., Falck, J. R., Capdevila, J., Gupta, K., Blair, I. A. & Potter, D. A., May 20 2011, In : Journal of Biological Chemistry. 286, 20, p. 17543-17559 17 p.

Research output: Contribution to journalArticle

51 Scopus citations
60 Scopus citations

Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease

Belcher, J. D., Chen, C., Nguyen, J., Milbauer, L., Abdulla, F., Alayash, A. I., Smith, A., Nath, K. A., Hebbel, R. P. & Vercellotti, G. M., Jan 16 2014, In : Blood. 123, 3, p. 377-390 14 p.

Research output: Contribution to journalArticle

251 Scopus citations
20 Scopus citations

H-ferritin ferroxidase induces cytoprotective pathways and inhibits microvascular stasis in transgenic sickle mice

Vercellotti, G. M., Khan, F. B., Nguyen, J., Chen, C., Bruzzone, C. M., Bechtel, H., Brown, G., Nath, K. A., Steer, C. J., Hebbel, R. P. & Belcher, J. D., Jan 1 2014, In : Frontiers in Pharmacology. 5 APR, Article 79.

Research output: Contribution to journalArticle

22 Scopus citations

Influence of morphine on pericyte-endothelial interaction: Implications for antiangiogenic therapy

Luk, K., Boatman, S., Johnson, K. N., Dudek, O. A., Ristau, N., Vang, D., Nguyen, J. & Gupta, K., Feb 6 2012, In : Journal of Oncology. 458385.

Research output: Contribution to journalArticle

23 Scopus citations

Inhaled carbon monoxide reduces leukocytosis in a murine model of sickle cell disease

Beckman, J. D., Belcher, J. D., Vineyard, J. V., Chen, C., Nguyen, J., Nwaneri, M. O., O'Sullivan, G., Gulbahce, E., Hebbel, R. P. & Vercellotti, G. M., Oct 1 2009, In : American Journal of Physiology - Heart and Circulatory Physiology. 297, 4, p. H1243-H1253

Research output: Contribution to journalArticle

30 Scopus citations

Mast cell activation contributes to sickle cell pathobiology and pain in mice

Vincent, L., Vang, D., Nguyen, J., Gupta, M., Luk, K., Ericson, M. E., Simone, D. A. & Gupta, K., Jan 1 2013, In : Blood. 122, 11, p. 1853-1862 10 p.

Research output: Contribution to journalArticle

96 Scopus citations

Morphine induces mesangial cell proliferation and glomerulopathy via κ-opioid receptors

Weber, M. L., Farooqui, M., Nguyen, J., Ansonoff, M., Pintar, J. E., Hebbel, R. P. & Gupta, K., Jun 1 2008, In : American Journal of Physiology - Renal Physiology. 294, 6, p. F1388-F1397

Research output: Contribution to journalArticle

29 Scopus citations

Morphine stimulates cancer progression and mast cell activation and impairs survival in transgenic mice with breast cancer

Nguyen, J., Luk, K., Vang, D., Soto, W., Vincent, L., Robiner, S., Saavedra, R., Li, Y., Gupta, P. & Gupta, K., Jan 1 2014, In : British Journal of Anaesthesia. 113, SUPPL. 1, p. i4-i13

Research output: Contribution to journalArticle

54 Scopus citations

MP4CO, a pegylated hemoglobin saturated with carbon monoxide, is a modulator of HO-1, inflammation, and vaso-occlusion in transgenic sickle mice

Belcher, J. D., Young, M., Chen, C., Nguyen, J., Burhop, K., Tran, P. & Vercellotti, G. M., Jan 1 2013, In : Blood. 122, 15, p. 2757-2764 8 p.

Research output: Contribution to journalArticle

49 Scopus citations

Oral carbon monoxide therapy in murine sickle cell disease: Beneficial effects on vasoocclusion, inflammation and anemia

Belcher, J. D., Gomperts, E., Nguyen, J., Chen, C., Abdulla, F., Kiser, Z. M., Gallo, D., Levy, H., Otterbein, L. E. & Vercellotti, G. M., Oct 2018, In : PloS one. 13, 10, e0205194.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Pain-related behaviors and neurochemical alterations in mice expressing sickle hemoglobin: Modulation by cannabinoids

Kohli, D. R., Li, Y., Khasabov, S. G., Gupta, P., Kehl, L. J., Ericson, M. E., Nguyen, J., Gupta, V., Hebbel, R. P., Simone, D. A. & Gupta, K., Jul 22 2010, In : Blood. 116, 3, p. 456-465 10 p.

Research output: Contribution to journalArticle

104 Scopus citations
67 Scopus citations

Small-molecule nociceptin receptor agonist ameliorates mast cell activation and pain in sickle mice

Vang, D., Paul, J. A., Nguyen, J., Tran, H., Vincent, L., Yasuda, D., Zaveri, N. T. & Gupta, K., Jan 1 2015, In : Haematologica. 100, 12, p. 1517-1525 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Sustained treatment of sickle cell mice with haptoglobin increases HO-1 and H-ferritin expression and decreases iron deposition in the kidney without improvement in kidney function

Shi, P. A., Choi, E., Chintagari, N. R., Nguyen, J., Guo, X., Yazdanbakhsh, K., Mohandas, N., Alayash, A. I., Manci, E. A., Belcher, J. D. & Vercellotti, G. M., Nov 1 2016, In : British journal of haematology. 175, 4, p. 714-723 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

The establishment of murine blood outgrowth endothelial cells and observations relevant to gene therapy

Somani, A., Nguyen, J., Milbauer, L. C., Solovey, A., Sajja, S. & Hebbel, R. P., Jul 2007, In : Translational Research. 150, 1, p. 30-39 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

The HDAC inhibitors trichostatin A and suberoylanilide hydroxamic acid exhibit multiple modalities of benefit for the vascular pathobiology of sickle transgenic mice

Hebbel, R. P., Vercellotti, G. M., Pace, B. S., Solovey, A. N., Kollander, R., Abanonu, C. F., Nguyen, J., Vineyard, J. V., Belcher, J. D., Abdulla, F., Osifuye, S., Eaton, J. W., Kelm, R. J. & Slungaard, A., Mar 25 2010, In : Blood. 115, 12, p. 2483-2490 8 p.

Research output: Contribution to journalArticle

48 Scopus citations
44 Scopus citations

Transgenic sickle mice have vascular inflammation

Belcher, J. D., Bryant, C. J., Nguyen, J., Bowlin, P. R., Kielbik, M. C., Bischof, J. C., Hebbel, R. P. & Vercellotti, G. M., May 15 2003, In : Blood. 101, 10, p. 3953-3959 7 p.

Research output: Contribution to journalArticle

152 Scopus citations