Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Regulation of tumor associated macrophage function by STAT5 in breast cancer
Schwertfeger, K. (PI), Farrar, M. A. (CoI), Muretta, J. M. (CoI), Nelson, A. C. (CoI), Bui, H. N. (Other Role), Haaning, A. M. (Other Role), He, Y. (Other Role) & Reese, L. E. (Other Role)
NIH NATIONAL CANCER INSTITUTE (NCI)
2/1/25 → 1/31/30
Project: Research project
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Cancer Center Support Grant
Yee, D. (PI), Antonarakis, E. (CoI), Beckman, K. B. (CoI), Betts, B. (CoI), Blaes, A. H. (CoI), Eaton, A. (CoI), Ellis, K. M. (CoI), Felices, M. (CoI), Geller, M. A. (CoI), Ghebre, R. G. (CoI), Griffin, T. J. (CoI), Hallstrom, T. C. (CoI), Harki, D. A. (CoI), Hatsukami, D. K. (CoI), Hirsch, B. A. (CoI), Huang, R. S. S. (CoI), Johnson, S. (CoI), Juckett, M. B. (CoI), Lange, C. A. (CoI), Le, C. T. (CoI), Luo, X. (CoI), McKenna, D. H. (CoI), Miller, J. S. (CoI), Moriarity, B. S. (CoI), Muretta, J. M. (CoI), Murray, T. (CoI), Nelson, H. H. (CoI), Ondrey, F. G. (CoI), Patel, M. R. (CoI), Pennell, C. A. (CoI), Petersen, A. J. (CoI), Peterson, L. A. (CoI), Poynter, J. (CoI), Pratt, R. J. (CoI), Sarver, A. L. (CoI), Schendzielos, D. L. (CoI), Schilz, A. (CoI), Schwertfeger, K. (CoI), Seelig, D. (CoI), Shimizu, Y. (CoI), Stepanov, I. (CoI), Temiz, N. A. (CoI), Ventz, S. (CoI), Villalta, P. W. (CoI), Vogel, R. (CoI), Wagner, J. E. (CoI), Wang, J. (CoI), Webber, B. R. (CoI), Weigel, B. J. (CoI), Yamamoto, M. (CoI) & Zhang, L. (CoI)
NIH NATIONAL CANCER INSTITUTE (NCI)
2/1/24 → 1/31/29
Project: Research project
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Engineering Protein Modulators of Notch Activation for CAR T-cell immunotherapy
Muretta, J. M. (PI), Allred, J. R. (CoI) & Gordon, W. R. (CoI)
NIH NATIONAL CANCER INSTITUTE (NCI)
8/1/23 → 7/31/26
Project: Research project
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Structural and molecular determinants of micro-Dystrophin stability and efficacyOption 2
Ervasti, J. M. (PI) & Muretta, J. M. (CoI)
7/1/23 → 6/30/25
Project: Research project
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Targeting allosteric scaffolding functions of Aurora kinase A in cancer
Levinson, N. M. (PI), Drake, J. M. (CoI) & Muretta, J. M. (CoI)
NIH NATIONAL CANCER INSTITUTE (NCI)
4/1/21 → 3/31/26
Project: Research project
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Human dystrophin tandem calponin homology actin-binding domain crystallized in a closed-state conformation
Streeter, O., Shi, K., Vavra, J. W., Aihara, H., Ervasti, J. M., Evans, R. & Muretta, J. M., Mar 1 2025, In: Acta Crystallographica Section D: Biological Crystallography. 81, Pt 3, p. 122-129 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Single-Chain Nanobody Inhibition of Notch and Avidity Enhancement Utilizing the β-Pore-Forming Toxin Aerolysin
Lemmex, A. C. D., Allred, J., Ostergard, J., Trask, J., Bui, H. N., Anderson, M. J. M., Kopp, B., Streeter, O., Smiley, A. T., Babilonia-Díaz, N. S., Blazar, B. R., Higgins, L. A., Gordon, P. M., Muretta, J. M. & Gordon, W. R., Mar 21 2025, In: ACS Chemical Biology. 20, 3, p. 656-669 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors
Rasmussen, D. M., Semonis, M. M., Greene, J. T., Muretta, J. M., Thompson, A. R., Toledo Ramos, S., Thomas, D. D., Pomerantz, W. C. K., Freedman, T. S. & Levinson, N. M., May 14 2024, In: eLife. 13, 13:RP95481.Research output: Contribution to journal › Article › peer-review
Open Access -
Desmoglein 2 Functions as a Receptor for Fatty Acid Binding Protein 4 in Breast Cancer Epithelial Cells
Chen, D., Wirth, K. M., Kizy, S., Muretta, J. M., Markowski, T. W., Yong, P., Sheka, A., Abdelwahab, H., Hertzel, A. V., Ikramuddin, S., Yamamoto, M. & Bernlohr, D. A., Aug 1 2023, In: Molecular Cancer Research. 21, 8, p. 836-848 13 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
HTS driven by fluorescence lifetime detection of FRET identifies activators and inhibitors of cardiac myosin
Muretta, J. M., Rajasekaran, D., Blat, Y., Little, S., Myers, M., Nair, C., Burdekin, B., Yuen, S. L., Jimenez, N., Guhathakurta, P., Wilson, A., Thompson, A. R., Surti, N., Connors, D., Chase, P., Harden, D., Barbieri, C. M., Adam, L. & Thomas, D. D., Jul 2023, In: SLAS Discovery. 28, 5, p. 223-232 10 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations
Datasets
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Analysis of the kinetics of binding of Protein Kinase A Inhibitor alpha (PKIa) to cAMP-dependent protein kinase a catalytic subunit (PKA-C)
Olivieri, C., Li, G. C. & Muretta, J. M., Data Repository for the University of Minnesota, 2020
DOI: 10.13020/jxk9-x251, http://hdl.handle.net/11299/212383
Dataset