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Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Engineering Protein Modulators of Notch Activation for CAR T-cell immunotherapy
Muretta, J. M., Allred, J. R. & Gordon, W. R.
NIH NATIONAL CANCER INSTITUTE (NCI)
8/1/23 → 7/31/26
Project: Research project
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Structural and molecular determinants of micro-Dystrophin stability and efficacyOption 2
Ervasti, J. M. & Muretta, J. M.
7/1/23 → 6/30/25
Project: Research project
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Targeting allosteric scaffolding functions of Aurora kinase A in cancer
Levinson, N. M., Drake, J. M. & Muretta, J. M.
NIH NATIONAL CANCER INSTITUTE (NCI)
4/1/21 → 3/31/26
Project: Research project
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A transformative drug discovery platform for allosteric kinase inhibitors
Levinson, N. M. & Muretta, J. M.
NIH NATIONAL CANCER INSTITUTE (NCI)
3/1/21 → 2/29/24
Project: Research project
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Mini-/Micro-Dystrophin Actin Binding Domain 1 Gain-of-Affinity Proposal
5/1/19 → 10/31/23
Project: Research project
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HTS driven by fluorescence lifetime detection of FRET identifies activators and inhibitors of cardiac myosin
Muretta, J. M., Rajasekaran, D., Blat, Y., Little, S., Myers, M., Nair, C., Burdekin, B., Yuen, S. L., Jimenez, N., Guhathakurta, P., Wilson, A., Thompson, A. R., Surti, N., Connors, D., Chase, P., Harden, D., Barbieri, C. M., Adam, L. & Thomas, D. D., Jul 2023, In: SLAS Discovery. 28, 5, p. 223-232 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Phosphorylation alters the mechanical stiffness of a model fragment of the dystrophin homologue utrophin
Ramirez, M. P., Rajaganapathy, S., Hagerty, A. R., Hua, C., Baxter, G. C., Vavra, J., Gordon, W. R., Muretta, J. M., Salapaka, M. V. & Ervasti, J. M., Feb 2023, In: Journal of Biological Chemistry. 299, 2, 102847.Research output: Contribution to journal › Article › peer-review
Open Access -
Enhancing interaction of actin and actin-binding domain 1 of dystrophin with modulators: Toward improved gene therapy for Duchenne muscular dystrophy
Guhathakurta, P., Carter, A. L., Thompson, A. R., Kurila, D., LaFrence, J., Zhang, L., Trask, J. R., Vanderheyden, B., Muretta, J. M., Ervasti, J. M. & Thomas, D. D., Dec 2022, In: Journal of Biological Chemistry. 298, 12, 102675.Research output: Contribution to journal › Article › peer-review
Open Access -
Allostery governs Cdk2 activation and differential recognition of CDK inhibitors
Majumdar, A., Burban, D. J., Muretta, J. M., Thompson, A. R., Engel, T. A., Rasmussen, D. M., Subrahmanian, M. V., Veglia, G., Thomas, D. D. & Levinson, N. M., Apr 2021, In: Nature Chemical Biology. 17, 4, p. 456-464 9 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Direct detection of the myosin super-relaxed state and interacting-heads motif in solution
Chu, S., Muretta, J. M. & Thomas, D. D., Oct 1 2021, In: Journal of Biological Chemistry. 297, 4, 101157.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations
Datasets
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Analysis of the kinetics of binding of Protein Kinase A Inhibitor alpha (PKIa) to cAMP-dependent protein kinase a catalytic subunit (PKA-C)
Olivieri, C., Li, G. C. & Muretta, J. M., Data Repository for the University of Minnesota, 2020
DOI: 10.13020/jxk9-x251, http://hdl.handle.net/11299/212383
Dataset