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Joseph M Muretta

20072020

Research output per year

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Projects

Mini-/Micro-Dystrophin Actin Binding Domain 1 Gain-of-Affinity Proposal

Muretta, J. M.

SAREPTA THERAPEUTICS, INC.

5/1/19 → 4/30/21

Project: Research project

    • Tuning Mitotic Kinesins Through Motor Domain Post Translational Modifications

    Muretta, J. M.

    MAYO CLINIC - JACKSONVILLE

    3/15/19 → 1/31/23

    Project: Research project

    Decoding the dynamic mechanism of allosteric activation

    Levinson, N. M., Muretta, J. M. & Veglia, G.

    NIH NIGMS NATL INST OF GENERAL

    1/1/18 → 12/31/22

    Project: Research project

    • A novel time-resolved fluorescence-based high-throughput

    Levinson, N. M. & Muretta, J. M.

    NIH NATIONAL CANCER INSTITUTE (NCI)

    8/1/17 → 7/31/20

    Project: Research project

    • Impact of Cardiomyopathy Mutations on Cardiac Myosin Str

    Thomas, D. D. & Muretta, J. M.

    Pennsylvania State University

    2/15/16 → 2/28/20

    Project: Research project

    • Research Output

    Multi-state recognition pathway of the intrinsically disordered protein kinase inhibitor by protein kinase A

    Olivieri, C., Wang, Y., Li, G. C., Subrahmanian, M. V., Kim, J., Stultz, B. R., Neibergall, M., Porcelli, F., Muretta, J. M., Thomas, D. D., Gao, J., Blumenthal, D. K., Taylor, S. S. & Veglia, G., Apr 2020, In : eLife. 9, e55607.

    Research output: Contribution to journal › Article

    Open Access

    • Converter domain mutations in myosin alter structural kinetics and motor function

    Gunther, L. K., Rohde, J. A., Tang, W., Walton, S. D., Unrath, W. C., Trivedi, D. V., Muretta, J. M., Thomas, D. D. & Yengo, C. M., Feb 1 2019, In : Journal of Biological Chemistry. 294, 5, p. 1554-1567 14 p.

    Research output: Contribution to journal › Article

    Open Access
    • 1 Scopus citations

    A dynamic mechanism for allosteric activation of aurora kinase a by activation loop phosphorylation

    Ruff, E. F., Muretta, J. M., Thompson, A. R., Lake, E. W., Cyphers, S., Albanese, S. K., Hanson, S. M., Behr, J. M., Thomas, D. D., Chodera, J. D. & Levinson, N. M., Feb 21 2018, In : eLife. 7, e32766.

    Research output: Contribution to journal › Article

    Open Access
    • 17 Scopus citations

    A posttranslational modification of the mitotic kinesin Eg5 that enhances its mechanochemical coupling and alters its mitotic function

    Muretta, J. M., Reddy, B. J. N., Scarabelli, G., Thompson, A. F., Jariwala, S., Major, J., Venere, M., Rich, J. N., Willard, B., Thomas, D. D., Stumpff, J., Grant, B. J., Gross, S. P. & Rosenfeld, S. S., Feb 20 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 8, p. E1779-E1788

    Research output: Contribution to journal › Article

    Open Access
    • 7 Scopus citations

    Mavacamten stabilizes an autoinhibited state of two-headed cardiac myosin

    Rohde, J. A., Roopnarine, O., Thomas, D. D. & Muretta, J. M., Aug 7 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 32, p. E7486-E7494

    Research output: Contribution to journal › Article

    Open Access
    • 19 Scopus citations