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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Human iPSC-Derived Chimeric Antigen Receptor Macrophages to Modulate Inflammation and Combat Tau-Induced Pathology
Sachs, J. N. (PI)
NIH NAT'L INSTITUTE ON AGING (NIA)
1/15/25 → 12/31/25
Project: Research project
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Advanced multiplexing technologies with innovative Dual-Channel Dark-FRET biosensors for dynamic monitoring of alpha-synuclein pathophysiology: From cellular to in vivo models
Sachs, J. N. (PI), Braun, A. R. (Co-Principal Investigator), Chen, L. (Co-Principal Investigator) & Dutton, J. R. (Co-Principal Investigator)
NATIONAL INSTITUTES OF HEALTH (NIH)
7/15/24 → 4/30/26
Project: Research project
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Innovation in monitoring tau-induced dysregulation of the autophagy lysosomal pathway
Sachs, J. N. (PI)
NIH NAT'L INSTITUTE ON AGING (NIA)
6/1/24 → 5/31/26
Project: Research project
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Exploiting New Fibril Structures to Understand the Biophysical Basis for Oligomerization and Toxicity of Alpha-Synuclein
Sachs, J. N. (PI), Odde, D. J. (CoI) & Pomerantz, W. C. (CoI)
NIH NAT INST OF NEURO DISORDERS & STROKE
9/30/20 → 8/31/25
Project: Research project
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Elucidating the biophysics of pre-fibrillar, toxic tau oligomers: from amino acid motifs to neuronal dysfunction
Sachs, J. N. (PI), Ashe, K. H. (CoI), Nelson, K. (CoI) & Yuan, S. (CoI)
NIH NAT'L INSTITUTE ON AGING (NIA)
9/30/21 → 5/31/24
Project: Research project
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Engineering Affibody Binders to Death Receptor 5 and Tumor Necrosis Factor Receptor 1 With Improved Stability
Nielsen, G. H., Sachs, J. N. & Hackel, B. J., 2025, (Accepted/In press) In: Biotechnology and bioengineering.Research output: Contribution to journal › Article › peer-review
Open Access -
Post-translational modification sites are present in hydrophilic cavities of alpha-synuclein, tau, FUS, and TDP-43 fibrils: A molecular dynamics study
Kochen, N. N., Seaney, D., Vasandani, V., Murray, M., Braun, A. R. & Sachs, J. N., Jul 2024, In: Proteins: Structure, Function and Bioinformatics. 92, 7, p. 854-864 11 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Advancements in a FRET Biosensor for Live-Cell Fluorescence-Lifetime High-Throughput Screening of Alpha-Synuclein
Braun, A. R., Kochen, N. N., Yuen, S. L., Liao, E. E., Cornea, R. L., Thomas, D. D. & Sachs, J. N., Jan 1 2023, In: ASN Neuro. 15Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Discovery of a Non-competitive TNFR1 Antagonist Affibody with Picomolar Monovalent Potency That Does Not Affect TNFR2 Function
Vunnam, N., Been, M. J., Huber, E., Paulson, C. N., Szymonski, S., Hackel, B. J. & Sachs, J. N., Apr 3 2023, In: Molecular pharmaceutics. 20, 4, p. 1884-1897 14 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Indirubin Inhibits TRAIL-Induced Activation of Death Receptor 5 in Jurkat Cells
Young, M. C., Vunnam, N., Rebbeck, R. T., Yuen, S. L., Thomas, D. D. & Sachs, J. N., Jan 2023, In: Natural Product Communications. 18, 1Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations