Projects per year
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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Understanding the structural dynamics of TNF receptors
NIH NIGMS NATL INST OF GENERAL
6/1/19 → 3/31/24
Project: Research project
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Elucidating the biophysics of pre-fibrillar, toxic tau oligomers: from amino acid motifs to neuronal dysfunction
Sachs, J. N., Ashe, K. H., Nelson, K. & Yuan, S.
NIH NAT'L INSTITUTE ON AGING (NIA)
9/30/21 → 5/31/23
Project: Research project
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HbS oligomers as a therapeutic target in sickle cell disease
National Heart, Lung, and Blood Institute
4/16/20 → 3/31/22
Project: Research project
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Indirubin Inhibits TRAIL-Induced Activation of Death Receptor 5 in Jurkat Cells
Young, M. C., Vunnam, N., Rebbeck, R. T., Yuen, S. L., Thomas, D. D. & Sachs, J. N., Jan 2023, In: Natural Product Communications. 18, 1Research output: Contribution to journal › Article › peer-review
Open Access -
Nimesulide, a COX-2 inhibitor, sensitizes pancreatic cancer cells to TRAIL-induced apoptosis by promoting DR5 clustering †
Vunnam, N., Young, M. C., Liao, E. E., Lo, C. H., Huber, E., Been, M. J., Thomas, D. D. & Sachs, J. N., 2023, In: Cancer Biology and Therapy. 24, 1, 2176692.Research output: Contribution to journal › Article › peer-review
Open Access -
pH Effects Can Dominate Chemical Shift Perturbations in 1H,15N-HSQC NMR Spectroscopy for Studies of Small Molecule/α-Synuclein Interactions
Pandey, A. K., Buchholz, C. R., Nathan Kochen, N., Pomerantz, W. C. K., Braun, A. R. & Sachs, J. N., Feb 15 2023, In: ACS Chemical Neuroscience. 14, 4, p. 800-808 9 p.Research output: Contribution to journal › Article › peer-review
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Broad Tricyclic Ring Inhibitors Block SARS-CoV-2 Spike Function Required for Viral Entry
Ratnapriya, S., Braun, A. R., Cervera benet, H., Carlson, D., Ding, S., Paulson, C. N., Mishra, N., Sachs, J. N., Aldrich, C. C., Finzi, A. & Herschhorn, A., Oct 14 2022, In: ACS Infectious Diseases. 8, 10, p. 2045-2058 14 p.Research output: Contribution to journal › Article › peer-review
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Fluorescence Lifetime Measurement of Prefibrillar Sickle Hemoglobin Oligomers as a Platform for Drug Discovery in Sickle Cell Disease
Vunnam, N., Hansen, S., Been, M. O., Lo, C. H., Pandey, A. K., Paulsen, C. N., Rohde, J. A., Thomas, D. D., Sachs, J. N. & Wood, D. K., Sep 12 2022, In: Biomacromolecules. 23, 9, p. 3822-3830 9 p.Research output: Contribution to journal › Article › peer-review
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