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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Elucidating the biophysics of pre-fibrillar, toxic tau oligomers: from amino acid motifs to neuronal dysfunction
Sachs, J. N., Ashe, K. H., Nelson, K. & Yuan, S.
NIH NAT'L INSTITUTE ON AGING (NIA)
9/30/21 → 5/31/23
Project: Research project
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HbS oligomers as a therapeutic target in sickle cell disease
NIH NAT'L HEART, LUNG, AND BLOOD INSTITU
4/16/20 → 3/31/22
Project: Research project
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Understanding the structural dynamics of TNF receptors
NIH NIGMS NATL INST OF GENERAL
6/1/19 → 3/31/24
Project: Research project
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Fluorescence-Based TNFR1 Biosensor for Monitoring Receptor Structural and Conformational Dynamics and Discovery of Small Molecule Modulators
Lo, C. H., Schaaf, T. M., Thomas, D. D. & Sachs, J. N., 2021, Methods in Molecular Biology. Humana Press Inc., Vol. 2248. p. 121-137 17 p. (Methods in Molecular Biology; vol. 2248).Research output: Chapter in Book/Report/Conference proceeding › Chapter
2 Scopus citations -
Potent inhibitors of toxic alpha-synuclein identified via cellular time-resolved FRET biosensors
Braun, A. R., Liao, E. E., Horvath, M., Kalra, P., Acosta, K., Young, M. C., Kochen, N. N., Lo, C. H., Brown, R., Evans, M. D., Pomerantz, W. C. K., Rhoades, E., Luk, K., Cornea, R. L., Thomas, D. D. & Sachs, J. N., Dec 2021, In: npj Parkinson's Disease. 7, 1, 52.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Conformational states of TNFR1 as a molecular switch for receptor function
Lo, C. H., Huber, E. C. & Sachs, J. N., Jun 1 2020, In: Protein Science. 29, 6, p. 1401-1415 15 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Discovery of Small Molecule Inhibitors of Huntingtin Exon 1 Aggregation by FRET-Based High-Throughput Screening in Living Cells
Lo, C. H., Pandey, N. K., Lim, C. K. W., Ding, Z., Tao, M., Thomas, D. D., Langen, R. & Sachs, J. N., Aug 5 2020, In: ACS Chemical Neuroscience. 11, 15, p. 2286-2295 10 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
How Do Ethanolamine Plasmalogens Contribute to Order and Structure of Neurological Membranes?
West, A., Zoni, V., Teague, W. E., Leonard, A. N., Vanni, S., Gawrisch, K., Tristram-Nagle, S., Sachs, J. N. & Klauda, J. B., Feb 6 2020, In: Journal of Physical Chemistry B. 124, 5, p. 828-839 12 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations