20002024
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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

  • 6 Similar Profiles
Synucleins Medicine & Life Sciences
Molecular Dynamics Simulation Medicine & Life Sciences
Lipid Bilayers Medicine & Life Sciences
Lipid bilayers Chemical Compounds
TNF-Related Apoptosis-Inducing Ligand Receptors Medicine & Life Sciences
Molecular dynamics Chemical Compounds
Membranes Medicine & Life Sciences
Computer simulation Chemical Compounds

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Projects 2007 2024

Research Output 2000 2019

Chondroitin sulfate proteoglycan 4 enhanced melanoma motility and growth requires a cysteine in the core protein transmembrane domain

Yang, J., Price, M. A., Wanshura, L. E. C., He, J., Yi, M., Welch, D. R., Li, G., Conner, S., Sachs, J., Turley, E. A. & McCarthy, J. B., Aug 1 2019, In : Melanoma research. 29, 4, p. 365-375 11 p.

Research output: Contribution to journalArticle

Cysteine
Melanoma
Growth
Focal Adhesion Protein-Tyrosine Kinases
Mitogen-Activated Protein Kinase 3

Multiscale Computational Modeling of Tubulin-Tubulin Lateral Interaction

Hemmat, M., Castle, B. T., Sachs, J. N. & Odde, D. J., Oct 1 2019, In : Biophysical journal. 117, 7, p. 1234-1249 16 p.

Research output: Contribution to journalArticle

Tubulin
Microtubules
Molecular Dynamics Simulation
Guanosine Triphosphate
Polymers
1 Citation (Scopus)

Noncompetitive inhibitors of TNFR1 probe conformational activation states

Lo, C. H., Schaaf, T. M., Grant, B. D., Lim, C. K. W., Bawaskar, P., Aldrich, C., Thomas, D. D. & Sachs, J. N., Jul 30 2019, In : Science signaling. 12, 592, eaav5637.

Research output: Contribution to journalArticle

Tumor Necrosis Factor Receptors
Chemical activation
Dimerization
Molecules
Ligands

Targeting the ensemble of heterogeneous tau oligomers in cells: A novel small molecule screening platform for tauopathies

Lo, C. H., Lim, C. K. W., Ding, Z., Wickramasinghe, S. P., Braun, A. R., Ashe, K. H., Rhoades, E., Thomas, D. D. & Sachs, J. N., Nov 2019, In : Alzheimer's and Dementia. 15, 11, p. 1489-1502 14 p.

Research output: Contribution to journalArticle

Tauopathies
Poisons
Biosensing Techniques
L 663536
Fluorescence Resonance Energy Transfer
Synucleins
Membranes