1971 …2021

Research output per year

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Research Output

1999
44 Scopus citations

Role of the nonheme Fe(II) center in the biosynthesis of the plant hormone ethylene

Rocklin, A. M., Tierney, D. L., Kofman, V., Brunhuber, N. M. W., Hoffman, B. M., Christoffersen, R. E., Reich, N. O., Lipscomb, J. D. & Que L., J., Jul 6 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 14, p. 7905-7909 5 p.

Research output: Contribution to journalArticle

92 Scopus citations

Solution structure of component B from methane monooxygenase derived through heteronuclear NMR and molecular modeling

Chang, S. L., Wallar, B. J., Lipscomb, J. D. & Mayo, K. H., May 4 1999, In : Biochemistry. 38, 18, p. 5799-5812 14 p.

Research output: Contribution to journalArticle

55 Scopus citations

Spectroscopic investigation of reduced protocatechuate 3,4-dioxygenase: Charge-induced alterations in the active site iron coordination environment

Davis, M. I., Wasinger, E. C., Westre, T. E., Zaleski, J. M., Orville, A. M., Lipscomb, J. D., Hedman, B., Hodgson, K. O. & Solomon, E. I., Dec 1 1999, In : Inorganic Chemistry. 38, 16, p. 3676-3683 8 p.

Research output: Contribution to journalArticle

15 Scopus citations
1998

Intermediates in Non-Heme Iron Intradiol Dioxygenase Catalysis

Lispscomb, J. D., Orville, A. M., Frazee, R. W., Dolbeare, K. B., Elango, N. & Ohlendorf, D. H., Dec 1 1998, In : ACS Symposium Series. 692, p. 387-402 16 p.

Research output: Contribution to journalArticle

2 Scopus citations

MMO: P450 in wolf's clothing?

Lipscomb, J. D. & Que, L., Jun 1 1998, In : Journal of Biological Inorganic Chemistry. 3, 3, p. 331-336 6 p.

Research output: Contribution to journalReview article

60 Scopus citations

Mossbauer evidence for antisymmetric exchange in a diferric synthetic complex and diferric methane monooxygenase

Kauffmann, K. E., Popescu, C. V., Dong, Y., Lipscomb, J. D., Que, L. & Münck, E., Sep 2 1998, In : Journal of the American Chemical Society. 120, 34, p. 8739-8746 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

The axial tyrosinate Fe3+ ligand in protocatechuate 3,4-dioxygenase influences substrate binding and product release: Evidence for new reaction cycle intermediates

Frazee, R. W., Orville, A. M., Dolbeare, K. B., Yu, H., Ohlendorf, D. H. & Lipscomb, J. D., Feb 24 1998, In : Biochemistry. 37, 8, p. 2131-2144 14 p.

Research output: Contribution to journalArticle

53 Scopus citations
1997

An Fe2/(IV)O2 diamond core structure for the key intermediate Q of methane monooxygenase

Shu, L., Nesheim, J. C., Kauffmann, K., Münck, E., Lipscomb, J. D. & Que, L., Jan 24 1997, In : Science. 275, 5299, p. 515-518 4 p.

Research output: Contribution to journalArticle

493 Scopus citations
29 Scopus citations

Crystal structure and resonance Raman studies of protocatechuate 3,4- dioxygenase complexed with 3,4-dihydroxyphenylacetate

Elgren, T. E., Orville, A. M., Kelly, K. A., Lipscomb, J. D., Ohlendorf, D. H. & Que, L., Sep 23 1997, In : Biochemistry. 36, 38, p. 11504-11513 10 p.

Research output: Contribution to journalArticle

74 Scopus citations

Crystal structure of the hydroxylase component of methane monooxygenase from Methylosinus trichosporium OB3b

Elango, N., Radhakrishnan, R., Froland, W. A., Wallar, B. J., Earhart, C. A., Lipscomb, J. D. & Ohlendorf, D. H., Mar 1997, In : Protein Science. 6, 3, p. 556-568 13 p.

Research output: Contribution to journalArticle

260 Scopus citations
154 Scopus citations
23 Scopus citations
61 Scopus citations

Methane monooxygenase and compound Q P450 chemistry without heme

Lipscomb, J. D., Dec 1 1997, In : FASEB Journal. 11, 9

Research output: Contribution to journalArticle

Probing the interactions between component B and the hydroxylase of methane monooxygenase

Wallar, B. J. & Lipscomb, J. D., Dec 1 1997, In : FASEB Journal. 11, 9

Research output: Contribution to journalArticle

Radiolytic reduction of methane monooxygenase dinuclear iron cluster at 77 K. EPR evidence for conformational change upon reduction or binding of component B to the diferric state

Davydov, A., Davydov, R., Gräslund, A., Lipscomb, J. D. & Andersson, K. K., Mar 14 1997, In : Journal of Biological Chemistry. 272, 11, p. 7022-7026 5 p.

Research output: Contribution to journalArticle

33 Scopus citations

Reaction of methylcubane with methane monooxygenase from.U. trichosrokil'm

Jin, V. & Lipscomb, J. D., Dec 1 1997, In : FASEB Journal. 11, 9, p. A1304

Research output: Contribution to journalArticle

Roles of the methane monooxygenase reductase component in the regulation of catalysis

Liu, Y., Nesheim, J. C., Paulsen, K. E., Stankovich, M. T. & Lipscomb, J. D., Apr 29 1997, In : Biochemistry. 36, 17, p. 5223-5233 11 p.

Research output: Contribution to journalArticle

48 Scopus citations

Spectroscopic characterization of substrate binding to the oxygenase component of benzoate 1,2-dioxygenase

Wolfe, M. D., Altier, D. J. & Lipscomb, J. D., Dec 1 1997, In : FASEB Journal. 11, 9, p. A1303

Research output: Contribution to journalArticle

Structure, reactivity, and regulation of methane monooxygenase catalytic cycle intermediates

Nesheim, J. C. & Lipscomb, J. D., Dec 1 1997, In : FASEB Journal. 11, 9

Research output: Contribution to journalArticle

Structures of competitive inhibitor complexes of protocatechuate 3,4- Dioxygenase: Multiple exogenous ligand binding orientations within the active site

Orville, A. M., Elango, N., Lipscomb, J. D. & Ohlendorf, D. H., Aug 19 1997, In : Biochemistry. 36, 33, p. 10039-10051 13 p.

Research output: Contribution to journalArticle

71 Scopus citations
1996

Dioxygen activation by enzymes containing binuclear non-heme iron clusters

Wallar, B. J. & Lipscomb, J. D., Nov 1 1996, In : Chemical Reviews. 96, 7, p. 2625-2657 33 p.

Research output: Contribution to journalArticle

1056 Scopus citations

Homoprotocatechuate 2,3-Dioxygenase from Brevibacterium fuscum: A dioxygenase with catalase activity

Miller, M. A. & Lipscomb, J. D., Mar 8 1996, In : Journal of Biological Chemistry. 271, 10, p. 5524-5535 12 p.

Research output: Contribution to journalArticle

64 Scopus citations
208 Scopus citations
43 Scopus citations
1995

Gating effects of component B on oxygen activation by the methane monooxygenase hydroxylase component

Liu, Y., Nesheim, J. C., Lee, S. K. & Lipscomb, J. D., Jan 1 1995, In : Journal of Biological Chemistry. 270, 42, p. 24662-24665 4 p.

Research output: Contribution to journalArticle

133 Scopus citations

X-ray Absorption Spectroscopic Studies of the Fe(II) Active Site of Catechol 2,3-Dioxygenase. Implications for the Extradiol Cleavage Mechanism

Shu, L., Chiou, Y. M., Orville, A. M., Miller, M. A., Lipscomb, J. D. & Que, L., May 1 1995, In : Biochemistry. 34, 20, p. 6649-6659 11 p.

Research output: Contribution to journalArticle

153 Scopus citations
1994

Biochemistry of the soluble methane monooxygenase

Lipscomb, J. D., Jan 1 1994, In : Annual Review of Microbiology. 48, p. 371-399 29 p.

Research output: Contribution to journalReview article

319 Scopus citations

Oxidation-Reduction Potentials of the Methane Monooxygenase Hydroxylase Component from Methylosinus trichosporium OB3b

Paulsen, K. E., Stankovich, M. T., Liu, Y., Lipscomb, J. D., Fox, B. G. & Münck, E., Jan 1 1994, In : Biochemistry. 33, 3, p. 713-722 10 p.

Research output: Contribution to journalArticle

93 Scopus citations

Preliminary crystallographic analysis of methane mono-oxygenase hydroxylase from Methylosinus trichosporium OB3b

Froland, W. A., Dyer, D. H., Radhakrishnan, R., Earhart, C. A., Lipscomb, J. D. & Ohlendorf, D. H., Feb 10 1994, In : Journal of Molecular Biology. 236, 1, p. 379-381 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

Preliminary crystallographic study of protocatechuate 3,4-Dioxygenase from Brevibacterium fuscum

Earhart, C. A., Radhakrishnan, R., Orville, A. M., Lipscomb, J. D. & Ohlendorf, D. H., Feb 10 1994, In : Journal of Molecular Biology. 236, 1, p. 374-376 3 p.

Research output: Contribution to journalArticle

14 Scopus citations

Structure of protocatechuate 3,4-dioxygenase from Pseudomonas aeruginosa at 2.15 Å resolution

Ohlendorf, D. H., Orville, A. M. & Lipscomb, J. D., Dec 15 1994, In : Journal of Molecular Biology. 244, 5, p. 586-608 23 p.

Research output: Contribution to journalArticle

161 Scopus citations

The Active Site of Hydroxylamine Oxidoreductase from Nitrosomonas: Evidence for a New Metal Cluster in Enzymes

Hendrich, M. P., Logan, M., Andersson, K. K., Arriero, D. M., Hooper, A. B. & Lipscomb, J. D., Dec 1 1994, In : Journal of the American Chemical Society. 116, 26, p. 11961-11968 8 p.

Research output: Contribution to journalArticle

40 Scopus citations
1993

A Transient Intermediate of the Methane Monooxygenase Catalytic Cycle Containing an FeIVFeIV Cluster

Lee, S. K., Froland, W. A., Lipscomb, J. D., Fox, B. G. & Münck, E., Jul 1 1993, In : Journal of the American Chemical Society. 115, 14, p. 6450-6451 2 p.

Research output: Contribution to journalEditorial

288 Scopus citations

Cloning, sequencing, and expression of the Pseudomonas putida protocatechuate 3,4-dioxygenase genes

Frazee, R. W., Livingston, D. M., LaPorte, D. C. & Lipscomb, J. D., Jan 1 1993, In : Journal of bacteriology. 175, 19, p. 6194-6202 9 p.

Research output: Contribution to journalArticle

48 Scopus citations

Mössbauer, EPR, and ENDOR Studies of the Hydroxylase and Reductase Components of Methane Monooxygenase from Methylosinus trichosporium OB3b

Fox, B. G., Surerus, K. K., Münck, E., Hendrick, M. P., Andersson, K. K., Froland, W. A. & Lipscomb, J. D., May 1 1993, In : Journal of the American Chemical Society. 115, 9, p. 3688-3701 14 p.

Research output: Contribution to journalArticle

166 Scopus citations

Pulsed EPR Studies of Mixed Valent [Fe(II)Fe(III)] Forms of Hemerythrin and Methane Monooxygenase: Evidence for a Hydroxide Bridge

Thomann, H., Bernardo, M., McCormick, J. M., Pulver, S., Solomon, E. I., Andersson, K. K. & Lipscomb, J. D., Sep 1 1993, In : Journal of the American Chemical Society. 115, 19, p. 8881-8882 2 p.

Research output: Contribution to journalArticle

61 Scopus citations

Purification and characterization of protocatechuate 2,3-dioxygenase from Bacillus macerans: A new extradiol catecholic dioxygenase

Wolgel, S. A., Dege, J. E., Perkins-Olson, P. E., Juarez-Garcia, C. H., Crawford, R. L., Munck, E. & Lipscomb, J. D., Jan 1 1993, In : Journal of bacteriology. 175, 14, p. 4414-4426 13 p.

Research output: Contribution to journalArticle

54 Scopus citations
52 Scopus citations
83 Scopus citations

Transient intermediates of the methane monooxygenase catalytic cycle

Lee, S. K., Nesheim, J. C. & Lipscomb, J. D., Oct 15 1993, In : Journal of Biological Chemistry. 268, 29, p. 21569-21577 9 p.

Research output: Contribution to journalArticle

294 Scopus citations
1992

Accessibility to the Active Site of Methane Monooxygenase: The First Demonstration of Exogenous Ligand Binding to the Diiron Cluster

Andersson, K. K., Elgren, T. E., Que, L. & Lipscomb, J. D., Oct 1 1992, In : Journal of the American Chemical Society. 114, 22, p. 8711-8713 3 p.

Research output: Contribution to journalArticle

30 Scopus citations

Cryptic Stereospecificity of Methane Monooxygenase

Priestley, N. D., Floss, H. G., Froland, W. A., Lipscomb, J. D., Williams, P. G. & Morimoto, H., Sep 1 1992, In : Journal of the American Chemical Society. 114, 19, p. 7561-7562 2 p.

Research output: Contribution to journalArticle

142 Scopus citations

EPR-spectroelectrochemistry of mammalian electron-transfer flavoprotein-ubiquinone oxidoreductase.

Paulsen, K. E., Orville, A. M., Frerman, F. E., Stankovich, M. T. & Lipscomb, J. D., 1992, In : Progress in clinical and biological research. 375, p. 69-73 5 p.

Research output: Contribution to journalArticle

Ligation of the diiron site of the hydroxylase component of methane monooxygenase. An electron nuclear double resonance study

Hendrich, M. P., Fox, B. G., Andersson, K. K., Debrunner, P. G. & Lipscomb, J. D., Jan 1 1992, In : Journal of Biological Chemistry. 267, 1, p. 261-269 9 p.

Research output: Contribution to journalArticle

48 Scopus citations
140 Scopus citations