If you made any changes in Pure, your changes will be visible here soon.

Research Output 1971 2019

2019

Salicylate 5-Hydroxylase: Intermediates in Aromatic Hydroxylation by a Rieske Monooxygenase

Rogers, M. & Lipscomb, J. D., Jan 1 2019, In : Biochemistry.

Research output: Contribution to journalArticle

Hydroxylation
Mixed Function Oxygenases
Oxygenases
Gentisates
Electrons

Soluble methane monooxygenase

Banerjee, R., Jones, J. C. & Lipscomb, J. D., Jun 20 2019, In : Annual Review of Biochemistry. 88, p. 409-431 23 p.

Research output: Contribution to journalArticle

methane monooxygenase
Methane
Temperature
Enzymes
Chemical activation
2018
5 Citations (Scopus)

Diiron monooxygenases in natural product biosynthesis

Komor, A. J., Jasniewski, A. J., Que, L. & Lipscomb, J. D., Jul 1 2018, In : Natural Product Reports. 35, 7, p. 646-659 14 p.

Research output: Contribution to journalReview article

Biosynthesis
Mixed Function Oxygenases
Biological Products
Amines
Hydroxylation
5 Citations (Scopus)
methane monooxygenase
X ray absorption
Methane
X-Rays
Iron
4 Citations (Scopus)

NRVS Studies of the Peroxide Shunt Intermediate in a Rieske Dioxygenase and Its Relation to the Native FeII O2 Reaction

Sutherlin, K. D., Rivard, B. S., Böttger, L. H., Liu, L. V., Rogers, M., Srnec, M., Park, K., Yoda, Y., Kitao, S., Kobayashi, Y., Saito, M., Seto, M., Hu, M., Zhao, J., Lipscomb, J. D. & Solomon, E. I., Apr 25 2018, In : Journal of the American Chemical Society. 140, 16, p. 5544-5559 16 p.

Research output: Contribution to journalArticle

Dioxygenases
Vibrational spectroscopy
Peroxides
Spectrum Analysis
Enzymes
2 Citations (Scopus)

Nuclear Resonance Vibrational Spectroscopy Definition of O 2 Intermediates in an Extradiol Dioxygenase: Correlation to Crystallography and Reactivity

Sutherlin, K. D., Wasada-Tsutsui, Y., Mbughuni, M. M., Rogers, M., Park, K., Liu, L. V., Kwak, Y., Srnec, M., Böttger, L. H., Frenette, M., Yoda, Y., Kobayashi, Y., Kurokuzu, M., Saito, M., Seto, M., Hu, M., Zhao, J., Alp, E. E., Lipscomb, J. D. & Solomon, E. I., Dec 5 2018, In : Journal of the American Chemical Society. 140, 48, p. 16495-16513 19 p.

Research output: Contribution to journalArticle

Vibrational spectroscopy
Crystallography
3,4-dihydroxyphenylacetate 2,3-dioxygenase
Spectrum Analysis
Enzymes
2017
3 Citations (Scopus)

CmlI N-Oxygenase Catalyzes the Final Three Steps in Chloramphenicol Biosynthesis without Dissociation of Intermediates

Komor, A. J., Rivard, B. S., Fan, R., Guo, Y., Que, L. & Lipscomb, J. D., Sep 19 2017, In : Biochemistry. 56, 37, p. 4940-4950 11 p.

Research output: Contribution to journalArticle

Oxygenases
Biosynthesis
Chloramphenicol
Catalytic Domain
Electrons
1 Citation (Scopus)

Corrigendum: Double-flow focused liquid injector for efficient serial femtosecond crystallography

Oberthuer, D., Knoška, J., Wiedorn, M. O., Beyerlein, K. R., Bushnell, D. A., Kovaleva, E. G., Heymann, M., Gumprecht, L., Kirian, R. A., Barty, A., Mariani, V., Tolstikova, A., Adriano, L., Awel, S., Barthelmess, M., Dörner, K., Xavier, P. L., Yefanov, O., James, D. R., Nelson, G. & 25 others, Wang, D., Calvey, G., Chen, Y., Schmidt, A., Szczepek, M., Frielingsdorf, S., Lenz, O., Snell, E., Robinson, P. J., Šarler, B., Belšak, G., Maček, M., Wilde, F., Aquila, A., Boutet, S., Liang, M., Hunter, M. S., Scheerer, P., Lipscomb, J. D., Weierstall, U., Kornberg, R. D., Spence, J. C. H., Pollack, L., Chapman, H. N. & Bajt, S., Jun 21 2017, In : Scientific reports. 7, 1 p.

Research output: Contribution to journalComment/debate

Crystallography
corrigendum
32 Citations (Scopus)

Double-flow focused liquid injector for efficient serial femtosecond crystallography

Oberthuer, D., Knoška, J., Wiedorn, M. O., Beyerlein, K. R., Bushnell, D. A., Kovaleva, E. G., Heymann, M., Gumprecht, L., Kirian, R. A., Barty, A., Mariani, V., Tolstikova, A., Adriano, L., Awel, S., Barthelmess, M., Dörner, K., Xavier, P. L., Yefanov, O., James, D. R., Nelson, G. & 25 others, Wang, D., Calvey, G., Chen, Y., Schmidt, A., Szczepek, M., Frielingsdorf, S., Lenz, O., Snell, E., Robinson, P. J., Šarler, B., Belšak, G., Maček, M., Wilde, F., Aquila, A., Boutet, S., Liang, M., Hunter, M. S., Scheerer, P., Lipscomb, J. D., Weierstall, U., Kornberg, R. D., Spence, J. C. H., Pollack, L., Chapman, H. N. & Bajt, S., Mar 16 2017, In : Scientific reports. 7, 44628.

Research output: Contribution to journalArticle

Crystallography
Dioxygenases
Temperature
RNA Polymerase II
Lasers
14 Citations (Scopus)
Hydrocarbons
Oxygenases
Iron
Ligands
Oxidants
3 Citations (Scopus)

Erratum: Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria (Cell Chemical Biology (2017) 24(10) (1259–1275.e6) (S2451945617302830)(10.1016/j.chembiol.2017.08.009))

Guo, Z., Sevrioukova, I. F., Denisov, I. G., Zhang, X., Chiu, T. L., Thomas, D. G., Hanse, E. A., Cuellar, R. A. D., Grinkova, Y. V., Langenfeld, V. W., Swedien, D. S., Stamschror, J. D., Alvarez, J., Luna, F., Galván, A., Bae, Y. K., Wulfkuhle, J. D., Gallagher, R. I., Petricoin, E. F., Norris, B. & 17 others, Flory, C. M., Schumacher, R. J., O'Sullivan, M. G., Cao, Q., Chu, H., Lipscomb, J. D., Atkins, W. M., Gupta, K., Kelekar, A., Blair, I. A., Capdevila, J. H., Falck, J. R., Sligar, S. G., Poulos, T. L., Georg, G. I., Ambrose, E. & Potter, D. A., Oct 19 2017, In : Cell Chemical Biology. 24, 10, 1 p.

Research output: Contribution to journalComment/debate

Biguanides
Mitochondria
Heme
Cytochrome P-450 Enzyme System
Cell Biology
3 Citations (Scopus)

Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria

Guo, Z., Sevrioukova, I. F., Denisov, I. G., Zhang, X., Chiu, T. L., Thomas, D. G., Hanse, E. A., Cuellar, R. A. D., Grinkova, Y. V., Langenfeld, V. W., Swedien, D. S., Stamschror, J. D., Alvarez, J., Luna, F., Galván, A., Bae, Y. K., Wulfkuhle, J. D., Gallagher, R. I., Petricoin, E. F., Norris, B. & 17 others, Flory, C. M., Schumacher, R. J., O'Sullivan, M. G., Cao, Q., Chu, H., Lipscomb, J. D., Atkins, W. M., Gupta, K., Kelekar, A., Blair, I. A., Capdevila, J. H., Falck, J. R., Sligar, S. G., Poulos, T. L., Georg, G. I., Ambrose, E. & Potter, D. A., Oct 19 2017, In : Cell Chemical Biology. 24, 10, p. 1259-1275.e6

Research output: Contribution to journalArticle

Open Access
Biguanides
Cytochrome P-450 CYP3A
Mitochondria
Heme
Cytochrome P-450 Enzyme System
16 Citations (Scopus)

High-Energy-Resolution Fluorescence-Detected X-ray Absorption of the Q Intermediate of Soluble Methane Monooxygenase

Castillo, R. G., Banerjee, R., Allpress, C. J., Rohde, G. T., Bill, E., Que, L., Lipscomb, J. D. & DeBeer, S., Dec 13 2017, In : Journal of the American Chemical Society. 139, 49, p. 18024-18033 10 p.

Research output: Contribution to journalArticle

Open Access
methane monooxygenase
X-Ray Absorption Spectroscopy
X ray absorption spectroscopy
X ray absorption
Catalytic Domain
1 Citation (Scopus)
Open Access
Kinetic parameters
Scaffolds
Medicine
Rate constants
Enzymes
7 Citations (Scopus)

Unprecedented (μ-1,1-Peroxo)diferric Structure for the Ambiphilic Orange Peroxo Intermediate of the Nonheme N-Oxygenase CmlI

Jasniewski, A. J., Komor, A. J., Lipscomb, J. D. & Que, L., Aug 2 2017, In : Journal of the American Chemical Society. 139, 30, p. 10472-10485 14 p.

Research output: Contribution to journalArticle

Open Access
X-Ray Absorption Spectroscopy
Oxygenases
X ray absorption spectroscopy
Oxidants
Catalytic Domain
4 Citations (Scopus)

Use of Isotopes and Isotope Effects for Investigations of Diiron Oxygenase Mechanisms

Banerjee, R., Komor, A. J. & Lipscomb, J. D., Jan 1 2017, Methods in Enzymology. Academic Press Inc., p. 239-290 52 p. (Methods in Enzymology; vol. 596).

Research output: Chapter in Book/Report/Conference proceedingChapter

Oxygenases
Isotopes
methane monooxygenase
Vibrational spectroscopy
Biosynthetic Pathways
2016
4 Citations (Scopus)

A Carboxylate Shift Regulates Dioxygen Activation by the Diiron Nonheme β-Hydroxylase CmlA upon Binding of a Substrate-Loaded Nonribosomal Peptide Synthetase

Jasniewski, A. J., Knoot, C., Lipscomb, J. D. & Que, L., Oct 18 2016, In : Biochemistry. 55, 41, p. 5818-5831 14 p.

Research output: Contribution to journalArticle

Peptide Synthases
Mixed Function Oxygenases
Chemical activation
Oxygen
Substrates
21 Citations (Scopus)

Crystal structure of CmlI, the arylamine oxygenase from the chloramphenicol biosynthetic pathway

Knoot, C. J., Kovaleva, E. G. & Lipscomb, J. D., Sep 1 2016, In : Journal of Biological Inorganic Chemistry. 21, 5-6, p. 589-603 15 p.

Research output: Contribution to journalArticle

Oxygenases
Biosynthetic Pathways
Chloramphenicol
Crystal structure
Catalytic Domain
1 Citation (Scopus)

Enzyme Substrate Complex of the H200C Variant of Homoprotocatechuate 2,3-Dioxygenase: Mössbauer and Computational Studies

Meier, K. K., Rogers, M. S., Kovaleva, E. G., Lipscomb, J. D., Bominaar, E. L. & Münck, E., Jun 20 2016, In : Inorganic Chemistry. 55, 12, p. 5862-5870 9 p.

Research output: Contribution to journalArticle

3,4-dihydroxyphenylacetate 2,3-dioxygenase
Tensors
enzymes
tensors
Electric fields
15 Citations (Scopus)

Mechanism for Six-Electron Aryl-N-Oxygenation by the Non-Heme Diiron Enzyme CmlI

Komor, A. J., Rivard, B. S., Fan, R., Guo, Y., Que, L. & Lipscomb, J. D., Jun 15 2016, In : Journal of the American Chemical Society. 138, 23, p. 7411-7421 11 p.

Research output: Contribution to journalArticle

Oxygenation
Chloramphenicol
Enzymes
Electrons
Oxidation
2015
10 Citations (Scopus)

A long-lived FeIII-(hydroperoxo) intermediate in the active H200C variant of homoprotocatechuate 2,3-dioxygenase: Characterization by mössbauer, electron paramagnetic resonance, and density functional theory methods

Meier, K. K., Rogers, M. S., Kovaleva, E. G., Mbughuni, M. M., Bominaar, E. L., Lipscomb, J. D. & Münck, E., Nov 2 2015, In : Inorganic Chemistry. 54, 21, p. 10269-10280 12 p.

Research output: Contribution to journalArticle

3,4-dihydroxyphenylacetate 2,3-dioxygenase
Density functional theory
Paramagnetic resonance
electron paramagnetic resonance
density functional theory
30 Citations (Scopus)

An unusual peroxo intermediate of the arylamine oxygenase of the chloramphenicol biosynthetic pathway

Makris, T. M., Vu, V. V., Meier, K. K., Komor, A. J., Rivard, B. S., Münck, E., Que, L. & Lipscomb, J. D., Feb 4 2015, In : Journal of the American Chemical Society. 137, 4, p. 1608-1617 10 p.

Research output: Contribution to journalArticle

Peptide Synthases
Oxygenases
Biosynthetic Pathways
Chloramphenicol
Peptides
16 Citations (Scopus)
Dioxygenases
Anhydrides
Protocatechuate-3,4-Dioxygenase
Catalytic Domain
X-Rays
19 Citations (Scopus)

Rate-Determining Attack on Substrate Precedes Rieske Cluster Oxidation during Cis-Dihydroxylation by Benzoate Dioxygenase

Rivard, B. S., Rogers, M., Marell, D. J., Neibergall, M. B., Chakrabarty, S., Cramer, C. & Lipscomb, J. D., Aug 4 2015, In : Biochemistry. 54, 30, p. 4652-4664 13 p.

Research output: Contribution to journalArticle

Dioxygenases
Benzoates
Electrons
Oxidation
Substrates
13 Citations (Scopus)

Structural Basis for Substrate and Oxygen Activation in Homoprotocatechuate 2,3-Dioxygenase: Roles of Conserved Active Site Histidine 200

Kovaleva, E. G., Rogers, M. S. & Lipscomb, J. D., Sep 1 2015, In : Biochemistry. 54, 34, p. 5329-5339 11 p.

Research output: Contribution to journalArticle

3,4-dihydroxyphenylacetate 2,3-dioxygenase
Histidine
Protons
Catalytic Domain
Chemical activation
94 Citations (Scopus)

Structure of the key species in the enzymatic oxidation of methane to methanol

Banerjee, R., Proshlyakov, Y., Lipscomb, J. D. & Proshlyakov, D. A., Feb 19 2015, In : Nature. 518, 7539, p. 431-434 4 p.

Research output: Contribution to journalArticle

methane monooxygenase
Methane
Methanol
Oxygen
Raman Spectrum Analysis
2014
22 Citations (Scopus)
Dioxygenases
Catalytic Domain
3,4-dihydroxyphenylacetate 2,3-dioxygenase
Metals
Electrons
18 Citations (Scopus)

Catalase (KatA) Plays a role in protection against anaerobic nitric oxide in Pseudomonas aeruginosa

Su, S., Panmanee, W., Wilson, J. J., Mahtani, H. K., Li, Q., VanderWielen, B. D., Makris, T. M., Rogers, M., McDaniel, C., Lipscomb, J. D., Irvin, R. T., Schurr, M. J., Lancaster, J. R., Kovall, R. A. & Hassett, D. J., Mar 24 2014, In : PloS one. 9, 3, e91813.

Research output: Contribution to journalArticle

Pseudomonas aeruginosa
Catalase
nitric oxide
catalase
Nitric Oxide
2 Citations (Scopus)

Life in a Sea of Oxygen

Lipscomb, J. D., May 30 2014, In : Journal of Biological Chemistry. 289, 22, p. 15141-15153 13 p.

Research output: Contribution to journalArticle

Biochemistry
Heme
Cytochrome P-450 Enzyme System
Iron
Oxygen
2013
33 Citations (Scopus)

Cyanobacterial aldehyde deformylase oxygenation of aldehydes yields n - 1 aldehydes and alcohols in addition to alkanes

Aukema, K. G., Makris, T. M., Stoian, S. A., Richman, J. E., Münck, E., Lipscomb, J. D. & Wackett, L. P., Oct 4 2013, In : ACS Catalysis. 3, 10, p. 2228-2238 11 p.

Research output: Contribution to journalArticle

Alkanes
Oxygenation
Aldehydes
Paraffins
Alcohols
28 Citations (Scopus)

Intermediate P* from soluble methane monooxygenase contains a diferrous cluster

Banerjee, R., Meier, K. K., Münck, E. & Lipscomb, J. D., Jun 25 2013, In : Biochemistry. 52, 25, p. 4331-4342 12 p.

Research output: Contribution to journalArticle

methane monooxygenase
Rate constants
Oxidation
Kinetics
Paramagnetic resonance
5 Citations (Scopus)

NO binding to Mn-substituted homoprotocatechuate 2,3-dioxygenase: Relationship to O2 reactivity

Hayden, J. A., Farquhar, E. R., Que, L., Lipscomb, J. D. & Hendrich, M. P., Oct 1 2013, In : Journal of Biological Inorganic Chemistry. 18, 7, p. 717-728 12 p.

Research output: Contribution to journalArticle

3,4-dihydroxyphenylacetate 2,3-dioxygenase
Nitric Oxide
Enzymes
Electrons
Ligands
19 Citations (Scopus)

Structure of a dinuclear iron cluster-containing β-hydroxylase active in antibiotic biosynthesis

Makris, T. M., Knoot, C. J., Wilmot, C. M. & Lipscomb, J. D., Sep 24 2013, In : Biochemistry. 52, 38, p. 6662-6671 10 p.

Research output: Contribution to journalArticle

Peptide Synthases
Hydroxylation
Biosynthesis
Viperidae
Mixed Function Oxygenases
2012
27 Citations (Scopus)

Characterization of an O 2 adduct of an active cobalt-substituted extradiol-cleaving catechol dioxygenase

Fielding, A. J., Lipscomb, J. D. & Que, L., Jan 18 2012, In : Journal of the American Chemical Society. 134, 2, p. 796-799 4 p.

Research output: Contribution to journalArticle

3,4-dihydroxyphenylacetate 2,3-dioxygenase
Dioxygenases
Cobalt
Substrates
Oxygenases
41 Citations (Scopus)

Structural and molecular characterization of iron-sensing hemerythrin-like domain within F-box and leucine-rich repeat protein 5 (FBXL5)

Thompson, J. W., Salahudeen, A. A., Chollangi, S., Ruiz, J. C., Brautigam, C. A., Makris, T. M., Lipscomb, J. D., Tomchick, D. R. & Bruick, R. K., Mar 2 2012, In : Journal of Biological Chemistry. 287, 10, p. 7357-7365 9 p.

Research output: Contribution to journalArticle

Hemerythrin
Iron
Iron Regulatory Protein 2
Ubiquitin-Protein Ligases
Regulator Genes
21 Citations (Scopus)

Structural basis for the role of tyrosine 257 of homoprotocatechuate 2,3-dioxygenase in substrate and oxygen activation

Kovaleva, E. G. & Lipscomb, J. D., Nov 6 2012, In : Biochemistry. 51, 44, p. 8755-8763 9 p.

Research output: Contribution to journalArticle

3,4-dihydroxyphenylacetate 2,3-dioxygenase
Tyrosine
Chemical activation
Oxygen
Substrates
26 Citations (Scopus)

Substrate-mediated oxygen activation by homoprotocatechuate 2,3-dioxygenase: Intermediates formed by a tyrosine 257 variant

Mbughuni, M. M., Meier, K. K., Münck, E. & Lipscomb, J. D., Nov 6 2012, In : Biochemistry. 51, 44, p. 8743-8754 12 p.

Research output: Contribution to journalArticle

3,4-dihydroxyphenylacetate 2,3-dioxygenase
Tyrosine
Chemical activation
Electrons
Chromophores
2011
13 Citations (Scopus)

Active-site structure of a β-hydroxylase in antibiotic biosynthesis

Vu, V. V., Makris, T. M., Lipscomb, J. D. & Que, L., May 11 2011, In : Journal of the American Chemical Society. 133, 18, p. 6938-6941 4 p.

Research output: Contribution to journalArticle

Biosynthesis
methane monooxygenase
Antibiotics
Mixed Function Oxygenases
Catalytic Domain
55 Citations (Scopus)

A hyperactive cobalt-substituted extradiol-cleaving catechol dioxygenase

Fielding, A. J., Kovaleva, E. G., Farquhar, E. R., Lipscomb, J. D. & Que, L., Feb 1 2011, In : Journal of Biological Inorganic Chemistry. 16, 2, p. 341-355 15 p.

Research output: Contribution to journalArticle

Dioxygenases
Cobalt
Metals
3,4-dihydroxyphenylacetate 2,3-dioxygenase
Kinetics
38 Citations (Scopus)

Oxy intermediates of homoprotocatechuate 2,3-dioxygenase: Facile electron transfer between substrates

Mbughuni, M. M., Chakrabarti, M., Hayden, J. A., Meier, K. K., Dalluge, J. J., Hendrich, M. P., Münck, E. & Lipscomb, J. D., Nov 29 2011, In : Biochemistry. 50, 47, p. 10262-10274 13 p.

Research output: Contribution to journalArticle

3,4-dihydroxyphenylacetate 2,3-dioxygenase
Electrons
Substrates
Iron
Electron Spin Resonance Spectroscopy
2010
43 Citations (Scopus)

A family of diiron monooxygenases catalyzing amino acid beta-hydroxylation in antibiotic biosynthesis

Makris, T. M., Chakrabarti, M., Münck, E. & Lipscomb, J. D., Aug 31 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 35, p. 15391-15396 6 p.

Research output: Contribution to journalArticle

Hydroxylation
Mixed Function Oxygenases
Peptide Synthases
Anti-Bacterial Agents
Amino Acids
103 Citations (Scopus)

Trapping and spectroscopic characterization of an FeIII-superoxo intermediate from a nonheme mononuclear iron-containing enzyme

Mbughuni, M. M., Chakrabarti, M., Hayden, J. A., Bominaar, E. L., Hendrich, M. P., Münck, E. & Lipscomb, J. D., Sep 28 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 39, p. 16788-16793 6 p.

Research output: Contribution to journalArticle

3,4-dihydroxyphenylacetate 2,3-dioxygenase
Iron
Enzymes
Heme
Catalytic Domain
2008
23 Citations (Scopus)

CD and MCD studies of the effects of component B variant binding on the biferrous active site of methane monooxygenase

Mitić, N., Schwartz, J. K., Brazeau, B. J., Lipscomb, J. D. & Solomon, E. I., Aug 12 2008, In : Biochemistry. 47, 32, p. 8386-8397 12 p.

Research output: Contribution to journalArticle

methane monooxygenase
Catalytic Domain
Ligands
Methane
Mixed Function Oxygenases
59 Citations (Scopus)

Electron paramagnetic resonance detection of intermediates in the enzymatic cycle of an extradiol dioxygenase

Gunderson, W. A., Zatsman, A. I., Emerson, J. P., Farquhar, E. R., Que, L., Lipscomb, J. D. & Hendrich, M. P., Nov 5 2008, In : Journal of the American Chemical Society. 130, 44, p. 14465-14467 3 p.

Research output: Contribution to journalArticle

Electron Spin Resonance Spectroscopy
Paramagnetic resonance
Enzymes
Substrates
Metalloids
44 Citations (Scopus)

Intermediate in the O-O bond cleavage reaction of an extradiol dioxygenase

Kovaleva, E. G. & Lipscomb, J. D., Oct 28 2008, In : Biochemistry. 47, 43, p. 11168-11170 3 p.

Research output: Contribution to journalArticle

3,4-dihydroxyphenylacetate 2,3-dioxygenase
Dioxygenases
Crystals
Substrates
Gems

Intermediates in the reaction cycle of methane monooxygenase: Structure and chemistry

Lipscomb, J. D., Lee, S. K., Nesheim, J. C., Jin, Y., Wallar, B. J. & Zhang, X. Y., Jan 2 2008, Iron Metabolism: Inorganic Biochemistry and Regulatory Mechanisms. Wiley, p. 323-339 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

methane monooxygenase
Mossbauer spectroscopy
Greenhouse gases
105 Citations (Scopus)

Mechanism of extradiol aromatic ring-cleaving dioxygenases

Lipscomb, J. D., Dec 1 2008, In : Current Opinion in Structural Biology. 18, 6, p. 644-649 6 p.

Research output: Contribution to journalReview article

Dioxygenases
Metals
Oxygen
Biomimetics
Catalytic Domain
23 Citations (Scopus)
Dioxygenases
Crystallography
Naphthalene
Catalytic Domain
Substrates
80 Citations (Scopus)

Swapping metals in Fe- and Mn-dependent dioxygenases: Evidence for oxygen activation without a change in metal redox state

Emerson, J. P., Kovaleva, E. G., Farquhar, E. R., Lipscomb, J. D. & Que, L., May 27 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 21, p. 7347-7352 6 p.

Research output: Contribution to journalArticle

Dioxygenases
Oxidation-Reduction
Metals
Oxygen
Enzymes