20062019

Research output per year

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Research Output

2019

Impact of Integrase Inhibition Compared with Nonnucleoside Inhibition on HIV Reservoirs in Lymphoid Tissues

Rothenberger, M., Nganou-Makamdop, K., Kityo, C., Ssali, F., Chipman, J. G., Beilman, G. J., Hoskuldsson, T., Anderson, J., Jasurda, J., Schmidt, T. E., Calisto, S. P., Pearson, H., Reimann, T., David, C., Perkey, K., Southern, P., Wietgrefe, S., Helgeson, E., Reilly, C., Haase, A. T. & 3 others, Douek, D. C., Fletcher, C. V. & Schacker, T. W., Jul 1 2019, In : Journal of Acquired Immune Deficiency Syndromes. 81, 3, p. 355-360 6 p.

Research output: Contribution to journalArticle

5 Scopus citations
2018

Conflicting evidence for HIV enrichment in CD32+ CD4 T cells

Pérez, L., Anderson, J., Chipman, J., Thorkelson, A., Chun, T. W., Moir, S., Haase, A. T., Douek, D. C., Schacker, T. W. & Boritz, E. A., Sep 20 2018, In : Nature. 561, 7723, p. E9-E16

Research output: Contribution to journalArticle

Open Access
14 Scopus citations

Lymphoid tissue fibrosis is associated with impaired vaccine responses

Kityo, C., Makamdop, K. N., Rothenberger, M. K., Chipman, J. G., Hoskuldsson, T., Beilman, G. J., Grzywacz, B. J., Mugyenyi, P., Ssali, F., Akondy, R. S., Anderson, J., Schmidt, T. E., Reimann, T., Callisto, S. P., Schoephoerster, J., Schuster, J., Muloma, P., Ssengendo, P., Moysi, E., Petrovas, C. & 13 others, Lanciotti, R., Zhang, L., Arévalo, M. T., Rodriguez, B., Ross, T. M., Trautmann, L., Sekaly, R. P., Lederman, M. M., Koup, R. A., Ahmed, R., Reilly, C. S., Douek, D. C. & Schacker, T. W., Jul 2 2018, In : Journal of Clinical Investigation. 128, 7, p. 2763-2773 11 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Transplantation of CCR5∆32 homozygous umbilical cord blood in a child with acute lymphoblastic leukemia and perinatally acquired HIV infection

Rothenberger, M. K., Wagner, J. E., Haase, A., Richman, D., Grzywacz, B. J., Strain, M., Lada, S., Estes, J., Fletcher, C. V., Podany, A. T., Anderson, J., Schmidt, T., Wietgrefe, S. W., Schacker, T. W. & Verneris, M. R., Jan 1 2018, In : Open Forum Infectious Diseases. 5, 5

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2017

Defining total-body AIDS-virus burden with implications for curative strategies

Estes, J. D., Kityo, C., Ssali, F., Swainson, L., Makamdop, K. N., Del Prete, G. Q., Deeks, S. G., Luciw, P. A., Chipman, J. G., Beilman, G. J., Hoskuldsson, T., Khoruts, A., Anderson, J., Deleage, C., Jasurda, J., Schmidt, T. E., Hafertepe, M., Callisto, S. P., Pearson, H., Reimann, T. & 12 others, Schuster, J., Schoephoerster, J., Southern, P., Perkey, K., Shang, L., Wietgrefe, S. W., Fletcher, C. V., Lifson, J. D., Douek, D. C., McCune, J. M., Haase, A. T. & Schacker, T. W., Nov 1 2017, In : Nature Medicine. 23, 11, p. 1271-1276 6 p.

Research output: Contribution to journalArticle

Open Access
106 Scopus citations
2016

IL-15 promotes activation and expansion of CD8+ T cells in HIV-1 infection

Younes, S. A., Freeman, M. L., Mudd, J. C., Shive, C. L., Reynaldi, A., Panigrahi, S., Estes, J. D., Deleage, C., Lucero, C., Anderson, J., Schacker, T. W., Davenport, M. P., McCune, J. M., Hunt, P. W., Lee, S. A., Serrano-Villar, S., Debernardo, R. L., Jacobson, J. M., Canaday, D. H., Sekaly, R. P. & 3 others, Rodriguez, B., Sieg, S. F. & Lederman, M. M., Jul 1 2016, In : Journal of Clinical Investigation. 126, 7, p. 2745-2756 12 p.

Research output: Contribution to journalArticle

Open Access
25 Scopus citations
2015

Antifibrotic therapy in simian immunodeficiency virus infection preserves CD4+ T-cell populations and improves immune reconstitution with antiretroviral therapy

Estes, J. D., Reilly, C., Trubey, C. M., Fletcher, C. V., Cory, T. J., Piatak, M., Russ, S., Anderson, J., Reimann, T. G., Star, R., Smith, A., Tracy, R. P., Berglund, A., Schmidt, T., Coalter, V., Chertova, E., Smedley, J., Haase, A. T., Lifson, J. D. & Schacker, T. W., Jan 1 2015, In : Journal of Infectious Diseases. 211, 5, p. 744-754 11 p.

Research output: Contribution to journalArticle

31 Scopus citations

Large number of rebounding/founder HIV variants emerge from multifocal infection in lymphatic tissues after treatment interruption

Rothenberger, M. K., Keele, B. F., Wietgrefe, S. W., Fletcher, C. V., Beilman, G. J., Chipman, J. G., Khoruts, A., Estes, J. D., Anderson, J., Callisto, S. P., Schmidt, T. E., Thorkelson, A., Reilly, C., Perkey, K., Reimann, T. G., Utay, N. S., Makamdop, K. N., Stevenson, M., Douek, D. C., Haase, A. T. & 1 others, Schacker, T. W., Mar 10 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 10, p. E1126-E1134

Research output: Contribution to journalArticle

134 Scopus citations

Lymphoid fibrosis occurs in long-term nonprogressors and persists with antiretroviral therapy but may be reversible with curative interventions

Sanchez, J. L., Hunt, P. W., Reilly, C. S., Hatano, H., Beilman, G. J., Khoruts, A., Jasurda, J. S., Somsouk, M., Thorkelson, A., Russ, S., Anderson, J., Deeks, S. G. & Schacker, T. W., Apr 1 2015, In : Journal of Infectious Diseases. 211, 7, p. 1068-1075 8 p.

Research output: Contribution to journalArticle

27 Scopus citations
2014

Glycoprotein B (gB) vaccines adjuvanted with AS01 or AS02 protect female guinea pigs against cytomegalovirus (CMV) viremia and offspring mortality in a CMV-challenge model

Schleiss, M. R., Choi, K. Y., Anderson, J., Mash, J. G., Wettendorff, M., Mossman, S. & Van Damme, M., May 13 2014, In : Vaccine. 32, 23, p. 2756-2762 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues

Fletcher, C. V., Staskus, K., Wietgrefe, S. W., Rothenberger, M., Reilly, C., Chipman, J. G., Beilman, G. J., Khoruts, A., Thorkelson, A., Schmidt, T. E., Anderson, J., Perkey, K., Stevenson, M., Perelson, A. S., Douek, D. C., Haase, A. T. & Schacker, T. W., Feb 11 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 6, p. 2307-2312 6 p.

Research output: Contribution to journalArticle

337 Scopus citations
2013

Impaired T-cell responses to sphingosine-1-phosphate in HIV-1 infected lymph nodes

Mudd, J. C., Murphy, P., Manion, M., Debernardo, R., Hardacre, J., Ammori, J., Hardy, G. A., Harding, C. V., Mahabaleshwar, G. H., Jain, M. K., Jacobson, J. M., Brooks, A. D., Lewis, S., Schacker, T. W., Anderson, J., Haddad, E. K., Cubas, R. A., Rodriguez, B., Sieg, S. F. & Lederman, M. M., Apr 11 2013, In : Blood. 121, 15, p. 2914-2922 9 p.

Research output: Contribution to journalArticle

21 Scopus citations
2008

Protein kinase inhibitors of the quinazoline class exert anti-cytomegaloviral activity in vitro and in vivo

Schleiss, M., Eickhoff, J., Auerochs, S., Leis, M., Abele, S., Rechter, S., Choi, Y., Anderson, J., Scott, G., Rawlinson, W., Michel, D., Ensminger, S., Klebl, B., Stamminger, T. & Marschall, M., Jul 1 2008, In : Antiviral Research. 79, 1, p. 49-61 13 p.

Research output: Contribution to journalArticle

52 Scopus citations
2006

Abnormal presence of semimature dendritic cells that induce regulatory T cells in HIV-infected subjects

Krathwohl, M. D., Schacker, T. W. & Anderson, J. L., Feb 15 2006, In : Journal of Infectious Diseases. 193, 4, p. 494-504 11 p.

Research output: Contribution to journalArticle

73 Scopus citations

Chemokine CXCL10 (IP-10) is sufficient to trigger an immune response to injected antigens in a mouse model

Krathwohl, M. D. & Anderson, J. L., Apr 5 2006, In : Vaccine. 24, 15, p. 2987-2993 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Cyclic cidofovir (cHPMPC) prevents congenital cytomegalovirus infection in a guinea pig model

Schleiss, M. R., Anderson, J. L. & McGregor, A., Mar 1 2006, In : Virology journal. 3, 9.

Research output: Contribution to journalArticle

14 Scopus citations