Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Increase Growth Arrest Protein 6 and soluble Axl-MER-Tyro3 kinase receptors reduce MPN-related efferocytosis to increase fibrosis and secondary acute myeloid leukemia
Beckman, J. D. (PI), Abdulla, F. R. (Other Role), Krenik, P. J. (Other Role) & Nguyen, J. (Other Role)
7/1/25 → 6/30/27
Project: Research project
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Engineered microsystems to asses endothelial contribution to myeloproliferative neoplasm thrombosis
Beckman, J. D. (PI)
NIH NATL HEART, LUNG AND BLOOD INSTITU
8/1/22 → 7/31/27
Project: Research project
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An open label, multicenter roll-over extension program (REP) to characterize the long- term safety andtolerability of iptacopan (LNP023) in patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) who havecompleted PNH Phase II and Phase III studies wit
Beckman, J. D. (PI)
NOVARTIS PHARMACEUTICALS CORPORATION
12/6/23 → 12/31/25
Project: Research project
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Role of Gas6-Axl-MERTK in Myeloproliferative Neoplasm Thrombosis
Beckman, J. D. (PI)
1/27/23 → 12/31/25
Project: Research project
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A multicenter, single arm, open-label trial to evaluate efficacy and safety of oral, twice daily iptacopan in adult PNH patients who have Hb>10 g/dL in response to anti-C5 antibody and switch and iptacopanadult PNH patients who have Hb >=10 g/dL in respo
Beckman, J. D. (PI)
NOVARTIS PHARMACEUTICALS CORPORATION
1/14/23 → 2/3/26
Project: Research project
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Iptacopan monotherapy resulted in increased hemoglobin level in patients with PNH and hemoglobin ≥10 g/dL after anti-C5 therapy
Kulasekararaj, A., de Fontbrune, F. S., Gaya, A., Weitz, I., Kuter, D. J., Patel, B. J., Araten, D. J., Singh, A., Jang, J. H., Kelly, R. J., Di Bona, E., Loschi, M., Pullarkat, V., Schubert, J., Notaro, R., Yenerel, M. N., Beckman, J., Blin, N., Murakhovskaya, I. & Panse, J. & 12 others, , Jun 2026, In: HemaSphere. 10, 6, e70384.Research output: Contribution to journal › Article › peer-review
Open Access -
Novel histone deacetylase inhibitor, CS014, attenuates in vivo thrombosis while maintaining hemostasis
Stanger, L., Yalavarthi, P., Adili, R., Gilmore, D., Hoang, T., Campbell, A., Krenik, P., Gustafsson, D., Fryklund, J., Fex, T., Oakes, N., Säljö, J. F., Dahlöf, B., Beckman, J. & Holinstat, M., Mar 2026, In: Journal of Thrombosis and Haemostasis. 24, 3, p. 1042-1055 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Understanding Sickle Cell Disease Endothelial Pathology Through the Lens of Liver Sinusoidal Endothelial Cells
Pradhan-Sundd, T., Branchford, B. & Beckman, J., May 2026, In: Cells. 15, 9, 846.Research output: Contribution to journal › Review article › peer-review
Open Access -
Oxygen-tunable endothelialized microvascular chip to assess hypoxia-reperfusion in sickle cell disease
Schad, S. R., Beckman, J. D., Lam, W. A. & Wood, D. K., Sep 23 2025, In: Lab on a chip. 25, 19, p. 4920-4933 14 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Scopus citations -
Missing the mark(ers): circulating endothelial cells and endothelial-derived extracellular vesicles are elevated in sickle cell disease plasma
Beckman, J. D., Zhang, P., Nguyen, J., Hebbel, R. P., Vercellotti, G. M. & Belcher, J. D., 2024, In: Frontiers in immunology. 15, 1493904.Research output: Contribution to journal › Article › peer-review
Open Access5 Link opens in a new tab Scopus citations