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  • 8 Similar Profiles
Histone Acetyltransferases Medicine & Life Sciences
Triage Medicine & Life Sciences
Acetylation Chemical Compounds
Histones Medicine & Life Sciences
Assays Chemical Compounds
Drug Discovery Medicine & Life Sciences
Throughput Chemical Compounds
Myoblasts Medicine & Life Sciences

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Research Output 2005 2019

3,3′-Disubstituted 5,5′-Bi(1,2,4-triazine) Derivatives with Potent in Vitro and in Vivo Antimalarial Activity

Xue, L., Shi, D. H., Harjani, J. R., Huang, F., Beveridge, J. G., Dingjan, T., Ban, K., Diab, S., Duffy, S., Lucantoni, L., Fletcher, S., Chiu, F. C. K., Blundell, S., Ellis, K., Ralph, S. A., Wirjanata, G., Teguh, S., Noviyanti, R., Chavchich, M., Creek, D. & 10 othersPrice, R. N., Marfurt, J., Charman, S. A., Cuellar, M. E., Strasser, J. M., Dahlin, J. L., Walters, M. A., Edstein, M. D., Avery, V. M. & Baell, J. B., Jan 1 2019, In : Journal of Medicinal Chemistry.

Research output: Contribution to journalArticle

Antimalarials
Plasmodium falciparum
Plasmodium vivax
Triazines
Parasitemia
2 Citations (Scopus)

ALARM NMR for HTS triage and chemical probe validation

Dahlin, J. L., Cuellar, M. E., Singh, G., Nelson, K., Strasser, J. M., Rappe, T., Xia, Y., Veglia, G. & Walters, M. A., Mar 1 2018, In : Current protocols in chemical biology. 10, 1, p. 91-117 27 p.

Research output: Contribution to journalArticle

Open Access
Triage
Magnetic Resonance Spectroscopy
Proteins
Antigens
Sulfhydryl Compounds
1 Citation (Scopus)

Reduction of protein kinase A-mediated phosphorylation of ATXN1-S776 in Purkinje cells delays onset of Ataxia in a SCA1 mouse model

Pérez Ortiz, J. M., Mollema, N., Toker, N., Adamski, C. J., O'Callaghan, B., Duvick, L., Friedrich, J., Walters, M. A., Strasser, J. M., Hawkinson, J. E., Zoghbi, H. Y., Henzler, C., Orr, H. T. & Lagalwar, S., Aug 1 2018, In : Neurobiology of Disease. 116, p. 93-105 13 p.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Purkinje Cells
Ataxia
Cyclic AMP-Dependent Protein Kinases
Phosphorylation
21 Citations (Scopus)

Assay interference and off-target liabilities of reported histone acetyltransferase inhibitors

Dahlin, J. L., Nelson, K., Strasser, J. M., Barsyte-Lovejoy, D., Szewczyk, M. M., Organ, S., Cuellar, M. E., Singh, G., Shrimp, J. H., Nguyen, N., Meier, J. L., Arrowsmith, C. H., Brown, P. J., Baell, J. B. & Walters, M. A., Dec 1 2017, In : Nature communications. 8, 1, 1527.

Research output: Contribution to journalArticle

Open Access
liabilities
Histone Acetyltransferases
inhibitors
Assays
counters
5 Citations (Scopus)

GSTO1-1 plays a pro-inflammatory role in models of inflammation, colitis and obesity

Menon, D., Innes, A., Oakley, A. J., Dahlstrom, J. E., Jensen, L. M., Brüstle, A., Tummala, P., Rooke, M., Casarotto, M. G., Baell, J. B., Nguyen, N., Xie, Y., Cuellar, M. E., Strasser, J. M., Dahlin, J. L., Walters, M. A., Burgio, G., O'Neill, L. A. J. & Board, P. G., Dec 1 2017, In : Scientific reports. 7, 1, 17832.

Research output: Contribution to journalArticle

Colitis
Obesity
Inflammation
Lymphatic System
Dextran Sulfate