1971 …2020

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2019

Interactions between the complement and endothelin systems in normal pregnancy and following placental ischemia

Regal, J. F., Lund, J. M., Wing, C. R., Root, K. M., McCutcheon, L., Bemis, L. T., Gilbert, J. S. & Fleming, S. D., Oct 2019, In : Molecular Immunology. 114, p. 10-18 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Role of B1 and B2 lymphocytes in placental ischemia-induced hypertension

Laule, C. F., Odean, E. J., Wing, C. R., Root, K. M., Towner, K. J., Hamm, C. M., Gilbert, J. S., Fleming, S. D. & Regal, J. F., Jan 1 2019, In : American Journal of Physiology - Heart and Circulatory Physiology. 317, 4, p. H732-H742

Research output: Contribution to journalArticle

1 Scopus citations
2018
Open Access
1 Scopus citations

The complement system in hypertension and renal damage in the Dahl SS rat

Regal, J. F., Laule, C. F., McCutcheon, L., Root, K. M., Lund, H., Hashmat, S. & Mattson, D. L., Mar 2018, In : Physiological Reports. 6, 6, e13655.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
2017

Effect of nicotine on placental ischemia-induced complement activation and hypertension in the rat

Laule, C. F., Wing, C. R., Odean, E. J., Wilcox, J. A., Gilbert, J. S. & Regal, J. F., Jan 1 2017, In : Journal of immunotoxicology. 14, 1, p. 235-240 6 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2016

Role of IgM and angiotensin II Type I receptor autoantibodies in local complement activation in placental ischemia-induced hypertension in the rat

Regal, J. F., Strehlke, M. E., Peterson, J. M., Wing, C. R., Parker, J. E., Nieto, N. F., Bemis, L. T., Gilbert, J. S. & Fleming, S. D., Oct 1 2016, In : Molecular Immunology. 78, p. 38-47 10 p.

Research output: Contribution to journalArticle

11 Scopus citations
2015

Neutrophil depletion attenuates placental ischemia-induced hypertension in the rat

Regal, J. F., Lillegard, K. E., Bauer, A. J., Elmquist, B. J., Loeks-Johnson, A. C. & Gilbert, J. S., Jul 2 2015, In : PloS one. 10, 7, e0132063.

Research output: Contribution to journalArticle

18 Scopus citations
2014

Differential effects of complement activation products C3a and C5a on cardiovascular function in hypertensive pregnant ratss

Lillegard, K. E., Loeks-Johnson, A. C., Opacich, J. W., Peterson, J. M., Bauer, A. J., Elmquist, B. J., Regal, R. R., Gilbert, J. & Regal, J. F., Nov 1 2014, In : Journal of Pharmacology and Experimental Therapeutics. 351, 2, p. 344-351 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Neonatal oxygen exposure alters airway hyper-responsiveness but not the response to allergen challenge in adult mice

Regal, J. F., Lawrence, B. P., Johnson, A. C., Lojovich, S. J. & O'Reilly, M. A., Mar 2014, In : Pediatric Allergy and Immunology. 25, 2, p. 180-186 7 p.

Research output: Contribution to journalArticle

15 Scopus citations
2013

Complement activation is critical for placental ischemia-induced hypertension in the rat

Lillegard, K. E., Johnson, A. C., Lojovich, S. J., Bauer, A. J., Marsh, H. C., Gilbert, J. & Regal, J. F., Nov 1 2013, In : Molecular Immunology. 56, 1-2, p. 91-97 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Pravastatin attenuates hypertension, oxidative stress, and angiogenic imbalance in rat model of placental ischemia-induced hypertension

Bauer, A. J., Banek, C. T., Needham, K., Gillham, H., Capoccia, S., Regal, J. F. & Gilbert, J., May 1 2013, In : Hypertension. 61, 5, p. 1103-1110 8 p.

Research output: Contribution to journalArticle

54 Scopus citations
2012

Immunotoxicology: fifty years of global scientific progress.

McKarns, S. C., Kerkvliet, N. I., Dean, J. H., Bonn, M. B., Cohen, M. D., Franko, J., Laiosa, M. D., Lawrence, B. P., Luebke, R. W., Luster, M. I., Miller, P. G., Palmer, R. K., Pfau, J. C., Raman, P., Regal, J. F., Rodgers, K. E., Schondelmeyer, R. S., Zhang, X. & Burns-Naas, L. A., Jan 1 2012, In : Journal of immunotoxicology. 9, 4, p. 339-340 2 p.

Research output: Contribution to journalArticle

2008

The development of novel approaches to the identification of chemical and protein respiratory allergens: Progress made from the conclusions and recommendations of ECVAM workshop 60a

Roggen, E., Aufderheide, M., Cetin, Y., Dearman, R. J., Gibbs, S., Hermanns, I., Kimber, I., Regal, J. F., Rovida, C., Warheit, D. B., Uhlig, S. & Casati, S., Nov 1 2008, In : ATLA Alternatives to Laboratory Animals. 36, 5, p. 591-598 8 p.

Research output: Contribution to journalArticle

18 Scopus citations
2007

Contributions of age and sex to heterogeneity of symptoms and effectiveness of secondary prevention strategies in asthma as modeled in the guinea pig

Regal, J. F., Regal, R. R., Meehan, J. L., Duan, M. & Mohrman, M. E., Jan 1 2007, In : Journal of immunotoxicology. 4, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

Mechanisms of occupational asthma: Not all allergens are equal

Regal, J. F., Greene, A. L. & Regal, R. R., Sep 10 2007, In : Environmental Health and Preventive Medicine. 12, 4, p. 165-171 7 p.

Research output: Contribution to journalArticle

1 Scopus citations
2006
11 Scopus citations
2005

Activation of the aryl hydrocarbon receptor increases pulmonary neutrophilia and diminishes host resistance to influenza A virus

Teske, S., Bohn, A. A., Regal, J. F., Neumiller, J. J. & Lawrence, B. P., Jul 1 2005, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 289, 1 33-1, p. L111-L124

Research output: Contribution to journalArticle

66 Scopus citations

Arginase activity differs with allergen in the effector phase of ovalbumin- versus trimellitic anhydride-induced asthma

Greene, A. L., Rutherford, M. S., Regal, R. R., Flickinger, G. H., Hendrickson, J. A., Giulivi, C., Mohrman, M. E., Fraser, D. G. & Regal, J. F., Dec 1 2005, In : Toxicological Sciences. 88, 2, p. 420-433 14 p.

Research output: Contribution to journalArticle

29 Scopus citations
2004

Immunologic effector mechanisms in animal models of occupational asthma

Regal, J. F., Dec 1 2004, In : Journal of immunotoxicology. 1, 1, p. 25-37 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

Murine asthma models.

Regal, J. F., 2004, In : Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.]. Chapter 18, p. Unit18.3

Research output: Contribution to journalArticle

1 Scopus citations
2002

Ozone differentially modulates airway responsiveness in atopic versus nonatopic guinea pigs

Schlesinger, R. B., Cohen, M. D., Gordon, T., Nadziejko, C., Zelikoff, J. T., Sisco, M., Regal, J. F. & Ménache, M. G., Jun 11 2002, In : Inhalation Toxicology. 14, 5, p. 431-457 27 p.

Research output: Contribution to journalArticle

7 Scopus citations

Ozone-induced modulation of airway hyperresponsiveness in guinea pigs.

Schlesinger, R. B., Cohen, M., Gordon, T., Nadziejko, C., Zelikoff, J. T., Sisco, M., Regal, J. F. & Ménache, M. G., Jun 2002, In : Research report (Health Effects Institute). 109

Research output: Contribution to journalArticle

4 Scopus citations

Trimellitic anhydride (TMA) dust induces airway obstruction and eosinophilia in non-sensitized guinea pigs

Larsen, C. P. & Regal, J. F., Sep 2 2002, In : Toxicology. 178, 2, p. 89-99 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Trimellitic anhydride-induced cellular infiltration into guinea pig lung varies with age but not gender

Larsen, C. P. & Regal, J. F., Mar 25 2002, In : International Archives of Allergy and Immunology. 127, 1, p. 63-72 10 p.

Research output: Contribution to journalArticle

4 Scopus citations
2001
18 Scopus citations

Trimellitic anhydride-induced eosinophilia in a mouse model of occupational asthma

Regal, J. F., Mohrman, M. E. & Sailstad, D. M., Sep 15 2001, In : Toxicology and Applied Pharmacology. 175, 3, p. 234-242 9 p.

Research output: Contribution to journalArticle

18 Scopus citations
2000

Dietary phytoestrogens have anti-inflammatory activity in a guinea pig model of asthma

Regal, J. F., Fraser, D. G., Weeks, C. E. & Greenberg, N. A., Apr 2000, In : Proceedings of the Society for Experimental Biology and Medicine. 223, 4, p. 372-378 7 p.

Research output: Contribution to journalArticle

50 Scopus citations

Minor role of the C3a receptor in systemic anaphylaxis in the guinea pig

Regal, J. F. & Klos, A., Jan 1 2000, In : Immunopharmacology. 46, 1, p. 15-28 14 p.

Research output: Contribution to journalArticle

19 Scopus citations
1998

The role of IgG1 and IgG2 in trimellitic anhydride-induced allergic response in the guinea pig lung

Fraser, D. G., Graziano, F. M., Larsen, C. P. & Regal, J. F., Jun 1998, In : Toxicology and Applied Pharmacology. 150, 2, p. 218-227 10 p.

Research output: Contribution to journalArticle

15 Scopus citations
1996

Mediators of C3A-peptide induced bronchoconstric-tion and changes in blood pressure

Xu, C., Fraser, P. O. & Regal, J. F., Dec 1 1996, In : FASEB Journal. 10, 3

Research output: Contribution to journalArticle

2 Scopus citations
11 Scopus citations
1995

Trimellitic anhydride-induced allergic response in the lung: Role of the complement system in cellular changes

Fraser, D. G., Regal, J. F. & Arndt, M. L., Jan 1 1995, In : Journal of Pharmacology and Experimental Therapeutics. 273, 2, p. 793-801 9 p.

Research output: Contribution to journalArticle

25 Scopus citations
1993

Enhancement of antigen-induced bronchoconstriction after intravascular complement activation with cobra venom factor: Reversal by granulocyte depletion

Regal, J. F., Fraser, D. G., Anderson, D. E. & Solem, L. E., Jan 1 1993, In : Journal of Immunology. 150, 8 I, p. 3496-3505 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Role of the complement system in antigen-induced bronchoconstriction and changes in blood pressure in the guinea pig

Regal, J. F., Fraser, D. G. & Toth, C. A., Jan 1 1993, In : Journal of Pharmacology and Experimental Therapeutics. 267, 2, p. 979-988 10 p.

Research output: Contribution to journalArticle

21 Scopus citations
1991
5 Scopus citations

Reduced Anaphylactic Responsiveness of Strain 2 Guinea Pigs

Heller, L. J. & Regal, J. F., Dec 1991, In : Proceedings of the Society for Experimental Biology and Medicine. 198, 3, p. 838-845 8 p.

Research output: Contribution to journalArticle

5 Scopus citations
1990

C5a/C5ades-Arg-induced increase in blood pressure in the guinea pig: role of thromboxane

Fraser, D. G. & Regal, J. F., Jan 1 1990, In : Immunopharmacology. 19, 1, p. 59-68 10 p.

Research output: Contribution to journalArticle

9 Scopus citations
13 Scopus citations

Recombinant human C5a-induced bronchoconstriction in the guinea-pig: A histamine independent mechanism

Regal, J. F. & Fraser, D. G., 1990, In : Pulmonary Pharmacology. 3, 2, p. 79-87 9 p.

Research output: Contribution to journalArticle

8 Scopus citations
3 Scopus citations
1989
2 Scopus citations

The role of C5a in hypersensitivity reactions in the lung

Regal, J. F., 1989, In : Pulmonary Pharmacology. 2, 1, p. 3-12 10 p.

Research output: Contribution to journalArticle

1 Scopus citations
1988
7 Scopus citations

Effect of adenosine on histamine release and atrioventricular conduction during guinea pig cardiac anaphylaxis

Heller, L. J. & Regal, J. F., Jan 1 1988, In : Circulation research. 62, 6, p. 1147-1158 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

Role of arachidonate metabolites in C5a-induced bronchoconstriction

Regal, J. F., Jan 1 1988, In : Journal of Pharmacology and Experimental Therapeutics. 246, 2, p. 542-547 6 p.

Research output: Contribution to journalArticle

14 Scopus citations
1987
5 Scopus citations

Mediators of C5a-induced bronchoconstriction

Regal, J. F., Aug 1 1987, In : Agents and Actions. 21, 3-4, p. 363-365 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Mediators of C5a-induced bronchoconstriction in the guinea pig

Regal, J. F. & Bell, R. L., Jan 1 1987, In : International Archives of Allergy and Immunology. 84, 4, p. 414-423 10 p.

Research output: Contribution to journalArticle

12 Scopus citations
1985

Anaphylaxis in the isolated heart perfused at constant high flow

Regal, J. F., Heller, L., Sunnarborg, L. & Nelson, R., Jan 1 1985, In : Federation Proceedings. 44, 6, p. No. 8575

Research output: Contribution to journalArticle