Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

  • 8 Similar Profiles
Antiviral Agents Medicine & Life Sciences
Ribonuclease H Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
HIV Reverse Transcriptase Medicine & Life Sciences
HIV-1 Medicine & Life Sciences
Endothelial Cells Medicine & Life Sciences
Protein-Tyrosine Kinases Medicine & Life Sciences
Human Immunodeficiency Virus Ribonuclease H Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2012 2017

Design, synthesis and biological evaluations of N-Hydroxy thienopyrimidine-2,4-diones as inhibitors of HIV reverse transcriptase-associated RNase H

Kankanala, J., Kirby, K. A., Huber, A. D., Casey, M. C., Wilson, D. J., Sarafianos, S. G. & Wang, Z. Dec 1 2017 In : European Journal of Medicinal Chemistry. 141, p. 149-161 13 p.

Research output: Research - peer-reviewArticle

Ribonuclease H
HIV Reverse Transcriptase
thienopyrimidine
Antiviral Agents
Viruses
3 Citations

Double-Winged 3-Hydroxypyrimidine-2,4-diones: Potent and Selective Inhibition against HIV-1 RNase H with Significant Antiviral Activity

Vernekar, S. K. V., Tang, J., Wu, B., Huber, A. D., Casey, M. C., Myshakina, N., Wilson, D. J., Kankanala, J., Kirby, K. A., Parniak, M. A., Sarafianos, S. G. & Wang, Z. Jun 22 2017 In : Journal of Medicinal Chemistry. 60, 12, p. 5045-5056 12 p.

Research output: Research - peer-reviewArticle

Human Immunodeficiency Virus Ribonuclease H
Ribonuclease H
Antiviral Agents
HIV-1
2-hydroxypyrimidine
2 Citations

Inhibition of human cytomegalovirus pUL89 terminase subunit blocks virus replication and genome cleavage

Wang, Y., Mao, L., Kankanala, J., Wang, Z. & Geraghty, R. J. Jan 1 2017 In : Journal of Virology. 91, 3, e02152-16

Research output: Research - peer-reviewArticle

Human herpesvirus 5
virus replication
genome
DNA
Endonucleases
8 Citations

3-Hydroxypyrimidine-2,4-dione-5-N-benzylcarboxamides Potently Inhibit HIV-1 Integrase and RNase H

Wu, B., Tang, J., Wilson, D. J., Huber, A. D., Casey, M. C., Ji, J., Kankanala, J., Xie, J., Sarafianos, S. G. & Wang, Z. Jul 14 2016 In : Journal of Medicinal Chemistry. 59, 13, p. 6136-6148 13 p.

Research output: Research - peer-reviewArticle

Ribonuclease H
Integrases
Antiviral Agents
HIV-1
2-hydroxypyrimidine
5 Citations

Deazaflavin Inhibitors of Tyrosyl-DNA Phosphodiesterase 2 (TDP2) Specific for the Human Enzyme and Active against Cellular TDP2

Marchand, C., Abdelmalak, M., Kankanala, J., Huang, S. Y., Kiselev, E., Fesen, K., Kurahashi, K., Sasanuma, H., Takeda, S., Aihara, H., Wang, Z. & Pommier, Y. Jul 15 2016 In : ACS Chemical Biology. 11, 7, p. 1925-1933 9 p.

Research output: Research - peer-reviewArticle

Enzymes
human TDP2 protein
tyrosyl-DNA phosphodiesterase
Derivatives
Phosphodiesterase Inhibitors