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Research Output 1959 2019

2019

High-sensitivity troponin T, NT-proBNP and glomerular filtration rate: A multimarker strategy for risk stratification in chronic heart failure

Aimo, A., Januzzi, J. L., Vergaro, G., Ripoli, A., Latini, R., Masson, S., Magnoli, M., Anand, I., Cohn, J. N., Tavazzi, L., Tognoni, G., Gravning, J., Ueland, T., Nymo, S. H., Rocca, H. P. B. L., Bayes-Genis, A., Lupón, J., de Boer, R. A., Yoshihisa, A., Takeishi, Y. & 10 othersEgstrup, M., Gustafsson, I., Gaggin, H. K., Eggers, K. M., Huber, K., Tentzeris, I., Wilson Tang, W. H., Grodin, J. L., Passino, C. & Emdin, M., Feb 15 2019, In : International Journal of Cardiology. 277, p. 166-172 7 p.

Research output: Contribution to journalArticle

Troponin T
Brain Natriuretic Peptide
Glomerular Filtration Rate
Heart Failure
C-Reactive Protein
2018

Cardiovascular Disease Progression: A Target for Therapy?

Cohn, J. N., Oct 1 2018, In : American Journal of Medicine. 131, 10, p. 1170-1173 4 p.

Research output: Contribution to journalReview article

Disease Progression
Cardiovascular Diseases
Arteries
Life Expectancy
Heart Ventricles
1 Citation (Scopus)

Heart Failure With Recovered Ejection Fraction in African Americans: Results From the African-American Heart Failure Trial

Chang, K. W., Beri, N., Nguyen, N. H., Arbit, B., Fox, S., Mojaver, S., Clopton, P., Tam, S. W., Taylor, A. L., Cohn, J. N., Maisel, A. S. & Anand, I., May 1 2018, In : Journal of cardiac failure. 24, 5, p. 303-309 7 p.

Research output: Contribution to journalArticle

African Americans
Heart Failure
Hospitalization
Confidence Intervals
Mortality

MY APPROACH to the patient with heart failure and improved ejection fraction

Cohn, J. N., Feb 1 2018, In : Trends in Cardiovascular Medicine. 28, 2, 1 p.

Research output: Contribution to journalComment/debate

Heart Failure
22 Citations (Scopus)

Prognostic value of high-sensitivity troponin T in chronic heart failure an individual patient data meta-analysis

Aimo, A., Januzzi, J. L., Vergaro, G. G. V., Ripoli, A., Latini, R., Masson, S., Magnoli, M., Anand, I. S., Cohn, J. N., Tavazzi, L., Tognoni, G., Gravning, J., Ueland, T., Nymo, S. H., Brunner-La Rocca, H. P., Genis, A. B., Lupón, J., De Boer, R. A., Yoshihisa, A., Takeishi, Y. & 10 othersEgstrup, M., Gustafsson, I., Gaggin, H. K., Eggers, K. M., Huber, K., Tentzeris, I., Tang, W. H. W., Grodin, J., Passino, C. & Emdin, M., Jan 1 2018, In : Circulation. 137, 3, p. 286-297 12 p.

Research output: Contribution to journalReview article

Troponin T
Meta-Analysis
Troponin
Heart Failure
Hospitalization
6 Citations (Scopus)

sST2 Predicts Outcome in Chronic Heart Failure Beyond NT−proBNP and High-Sensitivity Troponin T

Emdin, M., Aimo, A., Vergaro, G., Bayes-Genis, A., Lupón, J., Latini, R., Meessen, J., Anand, I., Cohn, J. N., Gravning, J., Gullestad, L., Broch, K., Ueland, T., Nymo, S. H., Brunner-La Rocca, H. P., de Boer, R. A., Gaggin, H. K., Ripoli, A., Passino, C. & Januzzi, J. L., Nov 6 2018, In : Journal of the American College of Cardiology. 72, 19, p. 2309-2320 12 p.

Research output: Contribution to journalArticle

Troponin T
Carcinogenesis
Heart Failure
Natriuretic Peptides
Cause of Death
13 Citations (Scopus)

Treatment with insulin is associated with worse outcome in patients with chronic heart failure and diabetes

Cosmi, F., Shen, L., Magnoli, M., Abraham, W. T., Anand, I. S., Cleland, J. G., Cohn, J. N., Cosmi, D., De Berardis, G., Dickstein, K., Franzosi, M. G., Gullestad, L., Jhund, P. S., Kjekshus, J., Køber, L., Lepore, V., Lucisano, G., Maggioni, A. P., Masson, S., McMurray, J. J. V. & 9 othersNicolucci, A., Petrarolo, V., Robusto, F., Staszewsky, L., Tavazzi, L., Teli, R., Tognoni, G., Wikstrand, J. & Latini, R., May 1 2018, In : European Journal of Heart Failure. 20, 5, p. 888-895 8 p.

Research output: Contribution to journalArticle

Heart Failure
Insulin
Propensity Score
Hospitalization
Therapeutics
2017
1 Citation (Scopus)

BMJ open protocol for the HAPPY Hearts study: Cardiovascular screening for the early detection of future adverse cardiovascular outcomes in middle-aged and older women: A prospective, observational cohort study

Boreskie, K. F., Kehler, D. S., Costa, E. C., Cortez, P. C., Berkowitz, I., Hamm, N. C., Moffatt, T. L., Stammers, A. N., Kimber, D. E., Hiebert, B. M., Kent, D. E., Cornish, D. E., Blewett, H., Nguyen, T., Arora, R. C., Strachan, S. M., Semenchuk, B. N., Hay, J. L., Cohn, J. N. & Duhamel, T. A., Jan 1 2017, In : BMJ open. 7, 11, e018249.

Research output: Contribution to journalArticle

Open Access
Observational Studies
Cohort Studies
Myocardial Infarction
Manitoba
Blood Pressure
2 Citations (Scopus)
Nebivolol
Atenolol
Placebos
Blood Pressure
Arteries

Neurohormonal activation and the management of heart failure

Cohn, J. N., Jun 1 2017, Congestive Heart Failure and Cardiac Transplantation: Clinical, Pathology, Imaging and Molecular Profiles. Springer International Publishing, p. 239-246 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Heart Failure
Vasoconstrictor Agents
Diuretics
Adrenergic beta-Antagonists
Digitalis
1 Citation (Scopus)

Office Blood Pressure and Cardiovascular Disease: Pathophysiologic Implications for Diagnosis and Treatment

Cohn, J. N., Duprez, D., Hoke, L., Florea, N. & Duval, S., May 1 2017, In : Hypertension. 69, 5, p. e14-e20

Research output: Contribution to journalArticle

Hematologic Diseases
Cardiovascular Diseases
Blood Pressure
12 Citations (Scopus)

Prognostic impact of diabetes and prediabetes on survival outcomes in patients with chronic heart failure: A post-hoc analysis of the GISSI-HF (Gruppo Italiano per lo Studio della Sopravvivenza nella Insufficienza Cardiaca-Heart Failure) trial

Dauriz, M., Targher, G., Temporelli, P. L., Lucci, D., Gonzini, L., Nicolosi, G. L., Marchioli, R., Tognoni, G., Latini, R., Cosmi, F., Tavazzi, L., Maggioni, A. P., Moccetti, T., Rossi, M. G., Pasotti, E., Vaghi, F., Roncarolo, P., Zunino, M. T., Matta, F., Actis Perinetto, E. & 31 othersGaita, F., Azzaro, G., Zanetta, M., Paino, A. M., Parravicini, U., Vegis, D., Conte, R., Ferraro, P., De Bernardi, A., Morelloni, S., Fagnani, M., Greco Lucchina, P., Montagna, L., Bellone, E., Sappè, D., Ferraro, F., Delucchi, M., Reynaud, S. G., Dore, M., La Brocca, A., Massobrio, N., Bo, L., Trinchero, R., Imazio, M., Brocchi, G., Nejrotti, A., Rissone, L., Gabasio, S., Zocchi, C., Cohn, J. N. & on behalf of the GISSI-HF Investigators, Jul 1 2017, In : Journal of the American Heart Association. 6, 7, e005156.

Research output: Contribution to journalArticle

Open Access
Prediabetic State
Diabetes Mellitus
Heart Failure
Cause of Death
Survival

The Paradox in Demonstrating Hydralazine-Nitrate Efficacy

Cohn, J. N., Sep 1 2017, In : JACC: Heart Failure. 5, 9, p. 640-641 2 p.

Research output: Contribution to journalEditorial

Isosorbide Dinitrate
Hydralazine
African Americans
Nitrates
Heart Failure
2016

Clinical trials: Heart failure treatment-clinical trials versus clinical practice

Cohn, J. N., Jun 1 2016, In : Nature Reviews Cardiology. 13, 6, p. 316-317 2 p.

Research output: Contribution to journalComment/debate

Heart Failure
Clinical Trials
22 Citations (Scopus)

Heart failure with improved ejection fraction: clinical characteristics, correlates of recovery, and survival

Florea, V., Rector, T. S., Anand, I. & Cohn, J. N., Jul 1 2016, In : Circulation: Heart Failure. 9, 7

Research output: Contribution to journalArticle

Heart Failure
Survival
Valsartan
Biomarkers
Hemodynamics

Slowing the Progression of Cardiovascular Disease

Cohn, J. N., Apr 12 2016, In : Journal of the American College of Cardiology. 67, 14, p. 1698-1700 3 p.

Research output: Contribution to journalComment/debate

Angiotensin Receptor Antagonists
Survival Analysis
Chronic Renal Insufficiency
Angiotensin-Converting Enzyme Inhibitors
Cardiovascular Diseases
3 Citations (Scopus)

Trials and Tribulations

Cohn, J. N., Mar 1 2016, In : Journal of Cardiac Failure. 22, 3, p. 180-181 2 p.

Research output: Contribution to journalEditorial

2015
29 Citations (Scopus)

Calculated plasma volume status and prognosis in chronic heart failure

Ling, H. Z., Flint, J., Damgaard, M., Bonfils, P. K., Cheng, A. S., Aggarwal, S., Velmurugan, S., Mendonca, M., Rashid, M., Kang, S., Papalia, F., Weissert, S., Coats, C. J., Thomas, M., Kuskowski, M. A., Cohn, J. N., Woldman, S., Anand, I. & Okonko, D. O., Jan 1 2015, In : European Journal of Heart Failure. 17, 1, p. 35-43 9 p.

Research output: Contribution to journalArticle

Plasma Volume
Heart Failure
Valsartan
Brain Natriuretic Peptide
Hematocrit
50 Citations (Scopus)

Loss in body weight is an independent prognostic factor for mortality in chronic heart failure: Insights from the GISSI-HF and Val-HeFT trials

Rossignol, P., Masson, S., Barlera, S., Girerd, N., Castelnovo, A., Zannad, F., Clemenza, F., Tognoni, G., Anand, I., Cohn, J. N., Anker, S. D., Tavazzi, L. & Latini, R., Apr 1 2015, In : European Journal of Heart Failure. 17, 4, p. 424-433 10 p.

Research output: Contribution to journalArticle

Heart Failure
Body Weight
Mortality
Plasma Volume
C-Reactive Protein
7 Citations (Scopus)

Prevention of cardiovascular disease

Cohn, J. N., Jul 1 2015, In : Trends in Cardiovascular Medicine. 25, 5, p. 436-442 7 p.

Research output: Contribution to journalReview article

Cardiovascular Diseases
Life Support Care
Health Care Costs
Early Diagnosis
Phenotype
9 Citations (Scopus)

Regular Wine Consumption in Chronic Heart Failure: Impact on Outcomes, Quality of Life, and Circulating Biomarkers

GISSI-HF Investigators, May 4 2015, In : Circulation: Heart Failure. 8, 3, p. 428-437 10 p.

Research output: Contribution to journalArticle

Open Access
Wine
Heart Failure
Biomarkers
Quality of Life
Depression
2014
11 Citations (Scopus)

Effect of Fixed-Dose Combination of isosorbide dinitrate and hydralazine on all hospitalizations and on 30-day readmission rates in patients with heart failure

Anand, I., Win, S., Rector, T. S., Cohn, J. N. & Taylor, A. L., Jan 1 2014, In : Circulation: Heart Failure. 7, 5, p. 759-765 7 p.

Research output: Contribution to journalArticle

Hospitalization
Heart Failure
Placebos
isosorbide-hydralazine combination
Mortality
22 Citations (Scopus)

G-protein beta-3 subunit genotype predicts enhanced benefit of fixed-dose isosorbide dinitrate and hydralazine: Results of A-HeFT

McNamara, D. M., Taylor, A. L., Tam, S. W., Worcel, M., Yancy, C. W., Hanley-Yanez, K., Cohn, J. N. & Feldman, A. M., Jan 1 2014, In : JACC: Heart Failure. 2, 6, p. 551-557 7 p.

Research output: Contribution to journalArticle

Isosorbide Dinitrate
Hydralazine
Guanine Nucleotides
African Americans
Carrier Proteins
9 Citations (Scopus)

Heart failure in 2013: Continue what we are doing to treat HF, but do it better

Cohn, J. N., Feb 1 2014, In : Nature Reviews Cardiology. 11, 2, p. 69-70 2 p.

Research output: Contribution to journalReview article

Heart Failure
Therapeutics
Clinical Trials
Equipment and Supplies
Pharmaceutical Preparations
58 Citations (Scopus)

Prognostic value of soluble ST2 in the Valsartan heart failure trial

Anand, I., Rector, T. S., Kuskowski, M. A., Snider, J. & Cohn, J. N., Jan 1 2014, In : Circulation: Heart Failure. 7, 3, p. 418-426 9 p.

Research output: Contribution to journalArticle

Valsartan
Heart Failure
Natriuretic Peptides
Proportional Hazards Models
Hospitalization
156 Citations (Scopus)

The autonomic nervous system and heart failure

Florea, V. & Cohn, J. N., May 23 2014, In : Circulation research. 114, 11, p. 1815-1826 12 p.

Research output: Contribution to journalReview article

Autonomic Nervous System
Heart Failure
Equipment and Supplies
Ventricular Remodeling
Sympathetic Nervous System
2013
88 Citations (Scopus)

Baseline and serial measurements of galectin-3 in patients with heart failure: Relationship to prognosis and effect of treatment with valsartan in the Val-HeFT

Anand, I., Rector, T. S., Kuskowski, M. A., Adourian, A., Muntendam, P. & Cohn, J. N., May 1 2013, In : European Journal of Heart Failure. 15, 5, p. 511-518 8 p.

Research output: Contribution to journalArticle

Valsartan
Galectin 3
Heart Failure
Hospitalization
Therapeutics
104 Citations (Scopus)

Clinical outcome endpoints in heart failure trials: A European Society of Cardiology Heart Failure Association consensus document

Zannad, F., Stein, K., Garcia, A. A., Anker, S. D., Armstrong, P. W., Calvo, G., Cleland, J. G. F., Cohn, J. N., Dickstein, K., Domanski, M. J., Ekman, I., Filippatos, G. S., Gheorghiade, M., Hernandez, A. F., Jaarsma, T., Koglin, J., Konstam, M., Kupfer, S., Maggioni, A. P., Mebazaa, A. & 20 othersMetra, M., Nowack, C., Pieske, B., Piña, I. L., Pocock, S. J., Ponikowski, P., Rosano, G., Ruilope, L. M., Ruschitzka, F., Severin, T., Solomon, S., Stockbridge, N. L., Stough, W. G., Swedberg, K., Tavazzi, L., Voors, A. A., Wasserman, S. M., Woehrle, H., Zalewski, A. & McMurray, J. J. V., Oct 1 2013, In : European Journal of Heart Failure. 15, 10, p. 1082-1094 13 p.

Research output: Contribution to journalReview article

Heart Failure
Clinical Trials
Mortality
Research Personnel
Morbidity
10 Citations (Scopus)
Lisinopril
Blood Vessels
Blood Pressure
Health
Therapeutics
9 Citations (Scopus)

Identifying the Risk and Preventing the Consequences of Cardiovascular Disease

Cohn, J. N., Jul 1 2013, In : Heart Lung and Circulation. 22, 7, p. 512-516 5 p.

Research output: Contribution to journalReview article

Cardiovascular Diseases
Blood Vessels
Arteries
Asymptomatic Diseases
Health
34 Citations (Scopus)

Interaction between baseline and early worsening of renal function and efficacy of renin-angiotensin-aldosterone systemblockade in patients with heart failure: Insights from the Val-HeFT study

Lesogor, A., Cohn, J. N., Latini, R., Tognoni, G., Krum, H., Massie, B., Zalewski, A., Kandra, A., Hua, T. A. & Gimpelewicz, C., Dec 16 2013, In : European Journal of Heart Failure. 15, 11, p. 1236-1244 9 p.

Research output: Contribution to journalArticle

Valsartan
Angiotensins
Aldosterone
Renin
Heart Failure

Preventing heart failure: A critique of strategies

Cohn, J. N., Apr 1 2013, In : Journal of Cardiac Failure. 19, 4, p. 211-213 3 p.

Research output: Contribution to journalReview article

Disease Management
Angiotensin-Converting Enzyme Inhibitors
Heart Failure
Hypertension
2 Citations (Scopus)

The message is clear prevent as well as treat acute myocardial infarction

Cohn, J. N., Dec 17 2013, In : Circulation. 128, 24, p. 2554-2556 3 p.

Research output: Contribution to journalEditorial

Hospitalization
Heart Failure
Myocardial Infarction
2012
13 Citations (Scopus)

Effect of fixed-dose combined isosorbide dinitrate/hydralazine in elderly patients in the african-american heart failure trial

Taylor, A. L., Sabolinski, M. L., Tam, S. W., Ziesche, S., Ghali, J. K., Archambault, W. T., Worcel, M. & Cohn, J. N., Aug 1 2012, In : Journal of Cardiac Failure. 18, 8, p. 600-606 7 p.

Research output: Contribution to journalArticle

Isosorbide Dinitrate
Hydralazine
African Americans
Heart Failure
Disease-Free Survival
1 Citation (Scopus)

Pharmacologic management of heart failure in the ambulatory setting

Givertz, M. M. & Cohn, J. N., Sep 1 2012, Cardiovascular Therapeutics: A Companion to Braunwald's Heart Disease: Fourth Edition. Elsevier Inc., p. 241-269 29 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Heart Failure

Reply

Cohn, J. N., Jun 1 2012, In : Journal of Cardiac Failure. 18, 6, 1 p.

Research output: Contribution to journalLetter

155 Citations (Scopus)

Serial measurement of cardiac troponin T using a highly sensitive assay in patients with chronic heart failure: Data from 2 large randomized clinical trials

Masson, S., Anand, I., Favero, C., Barlera, S., Vago, T., Bertocchi, F., Maggioni, A. P., Tavazzi, L., Tognoni, G., Cohn, J. N. & Latini, R., Jan 17 2012, In : Circulation. 125, 2, p. 280-288 9 p.

Research output: Contribution to journalArticle

Troponin T
Randomized Controlled Trials
Heart Failure
Valsartan
Brain Natriuretic Peptide

Stage B, a Pre-cursor of Heart Failure

Cohn, J. N. & Francis, G. S., Jan 1 2012, In : Heart Failure Clinics. 8, 1

Research output: Contribution to journalEditorial

Ventricular Remodeling
Left Ventricular Function
Disease Progression
Heart Failure

Stage B, A Precursor of Heart Failure, Part II

Cohn, J. N. & Francis, G. S., Jan 1 2012, In : Heart Failure Clinics. 8, 2, 1 p.

Research output: Contribution to journalEditorial

Disease Progression
Heart Failure

The problem with cardiovascular disease prevention guidelines

Cohn, J. N. & Duprez, D., Dec 1 2012, In : Current Treatment Options in Cardiovascular Medicine. 14, 6, p. 571-574 4 p.

Research output: Contribution to journalComment/debate

Cardiovascular Diseases
Guidelines
14 Citations (Scopus)

Underuse of cardiovascular preventive pharmacotherapy in patients presenting with ST-elevation myocardial infarction

Miedema, M. D., Cohn, J. N., Garberich, R. F., Knickelbine, T., Graham, K. J. & Henry, T. D., Aug 1 2012, In : American Heart Journal. 164, 2, p. 259-267 9 p.

Research output: Contribution to journalArticle

Drug Therapy
Coronary Disease
Primary Prevention
ST Elevation Myocardial Infarction
Databases
1 Citation (Scopus)

What's in a name?

Cohn, J. N., Mar 1 2012, In : Journal of Cardiac Failure. 18, 3, 1 p.

Research output: Contribution to journalComment/debate

Names
Heart Failure
2011
4 Citations (Scopus)

Atrial fibrillation and mortality in African American patients with heart failure: Results from the African American Heart Failure Trial (A-HeFT)

Mitchell, J. E., Tam, S. W., Trivedi, K., Taylor, A. L., O'Neal, W., Cohn, J. N. & Worcel, M., Jan 1 2011, In : American Heart Journal. 162, 1, p. 154-159 6 p.

Research output: Contribution to journalArticle

African Americans
Atrial Fibrillation
Heart Failure
Mortality
Blood Pressure
1 Citation (Scopus)

Commentary

Cohn, J. N., Jun 21 2011, In : Annals of Internal Medicine. 154, 12

Research output: Contribution to journalComment/debate

28 Citations (Scopus)

Direct-acting vasodilators

Cohn, J. N., McInnes, G. T. & Shepherd, A. M., Sep 1 2011, In : Journal of Clinical Hypertension. 13, 9, p. 690-692 3 p.

Research output: Contribution to journalReview article

Vasodilator Agents
Minoxidil
Hydralazine
Pressure
Antihypertensive Agents

Disease Prevention in Heart Failure

Florea, V. & Cohn, J. N., Dec 1 2011, Heart Failure. Elsevier Inc., p. 610-625 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Heart Failure
3 Citations (Scopus)

Inhibiting LV remodeling-the need for a targeted approach

Cohn, J. N., May 1 2011, In : Nature Reviews Cardiology. 8, 5, p. 248-249 2 p.

Research output: Contribution to journalArticle

Ventricular Remodeling
Angiotensin Receptor Antagonists
Renin-Angiotensin System
Angiotensin-Converting Enzyme Inhibitors
Renin
5 Citations (Scopus)

Is activation of the reninangiotensin system hazardous to your health?

Cohn, J. N., Sep 1 2011, In : European Heart Journal. 32, 17, p. 2096-2097 2 p.

Research output: Contribution to journalEditorial

Cerebrovascular Disorders
Diabetic Angiopathies
Peripheral Vascular Diseases
Renin
Coronary Disease
2 Citations (Scopus)

Should the blood pressure or the blood vessel be the target of therapy?

Cohn, J. N., Nov 1 2011, In : Expert Review of Cardiovascular Therapy. 9, 11, p. 1397-1401 5 p.

Research output: Contribution to journalReview article

Blood Vessels
Blood Pressure
Hypertension
Cardiovascular System
Vascular Diseases
15 Citations (Scopus)

Vascular and cardiac functional and structural screening to identify risk of future morbid events: Preliminary observations

Duprez, D., Florea, N., Zhong, W., Grandits, G. A., Hawthorne, C. K., Hoke, L. & Cohn, J. N., Sep 1 2011, In : Journal of the American Society of Hypertension. 5, 5, p. 401-409 9 p.

Research output: Contribution to journalArticle

Blood Vessels
Cardiovascular Abnormalities
Asymptomatic Diseases
ROC Curve
LDL Cholesterol