Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Chemistry and Chemical Biology, Cornell University
Award Date: Aug 25 2010
Research Interest Keywords
- Nucleotide Metabolism
- structural biology
- Biomolecular Condensates
- Drug Discovery
- Mechanistic Enzymology
- X-ray Crystallography
- Single Particle Cryo-EM
- Microscopy
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Collaborations and top research areas from the last five years
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Establishing a critical path to success for a novel immune-enhancing treatment
French, J. (PI)
11/4/24 → 12/31/24
Project: Research project
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Development of a Digital Acoustofluidic System for Automating Liquid Handling in Biomedical Research
French, J. (PI)
DUKE UNIVERSITY, NATIONAL INSTITUTES OF HEALTH (NIH)
6/1/23 → 5/31/25
Project: Research project
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Collaborative Research: REU Site: Molecular Interactions Virtual REU
French, J. (PI)
THE NATIONAL SCIENCE FOUNDATION
3/1/22 → 2/28/25
Project: Research project
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Development of an immune activating antimicrobial drug
French, J. (PI)
12/1/23 → 11/30/24
Project: Research project
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Function of the Sts protein phosphodiesterase domain
French, J. (PI)
NIH Nat'l Inst of Allergy & Infect Dis
5/19/21 → 4/30/24
Project: Research project
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Elucidating the Signal Transduction Mechanism of the Blue-Light-Regulated Photoreceptor YtvA: From Photoactivation to Downstream Regulation
He, Y. L., Collado, J. T., Iuliano, J. N., Woroniecka, H. A., Hall, C. R., Gil, A. A., Laptenok, S. P., Greetham, G. M., Illarionov, B., Bacher, A., Fischer, M., French, J. B., Lukacs, A., Meech, S. R. & Tonge, P. J., Mar 15 2024, In: ACS Chemical Biology. 19, 3, p. 696-706 11 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Rebamipide and Derivatives are Potent, Selective Inhibitors of Histidine Phosphatase Activity of the Suppressor of T Cell Receptor Signaling Proteins
Aziz, F., Reddy, K., Fernandez Vega, V., Dey, R., Hicks, K. A., Rao, S., Jordan, L. O., Smith, E., Shumate, J., Scampavia, L., Carpino, N., Spicer, T. P. & French, J. B., Feb 8 2024, In: Journal of medicinal chemistry. 67, 3, p. 1949-1960 12 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Characterization of an Acinetobacter baumannii Monofunctional Phosphomethylpyrimidine Kinase That Is Inhibited by Pyridoxal Phosphate
De Vitto, H., Belfon, K. K. J., Sharma, N., Toay, S., Abendroth, J., Dranow, D. M., Lukacs, C. M., Choi, R., Udell, H. S., Willis, S., Barrera, G., Beyer, O., Li, T. D., Hicks, K. A., Torelli, A. T. & French, J. B., 2023, (Accepted/In press) In: Biochemistry.Research output: Contribution to journal › Article › peer-review
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Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms
Le, L. T. M., Thompson, J. R., Dehghani-Ghahnaviyeh, S., Pant, S., Dang, P. X., French, J. B., Kanikeyo, T., Tajkhorshid, E. & Alam, A., Feb 1 2023, In: EMBO Journal. 42, 3, e111065.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Human uridine 5′-monophosphate synthase stores metabolic potential in inactive biomolecular condensates
Kim-Holzapfel, D. M., Dey, R., Richardson, B. C., Arachchige, D., Reddy, K., De Vitto, H., Bhandari, J. & French, J. B., Mar 2023, In: Journal of Biological Chemistry. 299, 3, 102949.Research output: Contribution to journal › Article › peer-review
Open Access
Press/Media
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Breakthrough research using light- activated proteins for targeted therapy
10/30/20
1 item of Media coverage
Press/Media: Research
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Work is a team effort at the Hormel Institute
Bode, A. M., French, J., Liu, B. & Dennison, G. M.
4/25/20
1 item of Media coverage
Press/Media: Research