Projects per year
Personal profile
Research interests
Sepsis; systemic inflammatory response syndrome (SIRS); inflammatory response; acute respiratory distress syndrome (ARDS)/acute lung injury (ALI); MRSA infection, pathophysiology, and epidemiology; high consequence infectious diseases (particularly impact on pediatric populations).
Research Interest Keywords
- Sepsis
- SIRS
- ARDS
- ALI
- High consequence infectious diseases
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 1 No Poverty
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SDG 2 Zero Hunger
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SDG 3 Good Health and Well-being
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SDG 10 Reduced Inequalities
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Collaborations and top research areas from the last five years
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NIAID Centers of Excellence for Influenza Research and Response (CEIRR)
Hume, J. (PI)
BOSTON CHILDREN'S HOSPITAL, NATIONAL INSTITUTES OF HEALTH (NIH)
4/1/23 → 3/31/27
Project: Research project
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Assessment of MODS and PersonaLized Exposures of Antibiotics
Hume, J. (PI)
THE CHILDREN'S HOSPITAL OF PHILADELPHIA, NIH NATL INST OF CHILD HEALTH/HUMAN DEV
9/22/21 → 8/31/27
Project: Research project
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Collaborative Pediatric Critical Care Research Network - Clinical Site
Steiner, M. E. (PI), Heneghan, J. (CoI), Hume, J. (CoI) & Fischer, G. (Co-Principal Investigator)
NIH NATL INST OF CHILD HEALTH/HUMAN DEV
8/18/21 → 7/31/27
Project: Research project
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I-ACT Site Agreement
Hume, J. (PI) & Steiner, M. E. (Prior Principal Investigator)
INST FOR ADVANCED CLINICAL TRIALS FOR CH, DHHS FOOD & DRUG ADMINISTRATION (FDA)
7/12/18 → 7/11/28
Project: Research project
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National Ebola Training and Education Center (NETEC)
Kline, S. E. (PI) & Hume, J. (CoI)
UNIVERSITY OF NEBRASKA MEDICAL CENTER, U.S. DEPARTMENT OF HEALTH & HUMAN SVCS
9/30/25 → 9/29/26
Project: Research project
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Cefepime pharmacokinetics in critically ill children with multiple organ dysfunction syndrome using volumetric absorptive microsampling
on behalf of Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network, Jul 2026, In: Antimicrobial agents and chemotherapy. 70, 7, e01736-25.Research output: Contribution to journal › Article › peer-review
Open Access -
Characteristics of Young Children Hospitalized With Acute Respiratory Failure From Infection With Respiratory Syncytial Virus, SARS-CoV-2, or Both, November 2023–March 2024
COVID-19 Investigators, Mar 1 2026, In: Open Forum Infectious Diseases. 13, 3, ofag088.Research output: Contribution to journal › Article › peer-review
Open Access -
Integrating pulmonary and systemic transcriptomes to characterize lung injury after pediatric hematopoietic stem cell transplant
Pearce, E. M., Evans, E., Mayday, M. Y., Reyes, G., Simon, M. R., Blum, J., Kim, H., Mu, J., Shaw, P. J., Rowan, C. M., Auletta, J. J., Martin, P. L., Hurley, C., Kreml, E. M., Qayed, M., Abdel-Azim, H., Keating, A. K., Cuvelier, G. D. E., Hume, J. R. & Killinger, J. S. & 19 others, , Sep 9 2025, In: JCI Insight. 10, 17, e194440.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Nirsevimab Effectiveness Against Intensive Care Unit Admission for Respiratory Syncytial Virus in Infants - 24 States, December 2024-April 2025
Zambrano, L. D., Simeone, R. M., Newhams, M. M., Payne, A. B., Halasa, N. B., Orzel-Lockwood, A. O., Calixte, J. M., Kamidani, S., Crandall, H., Cameron, M. A., Schuster, J. E., Maddux, A. B., Chiotos, K., Irby, K., Shein, S. L., Staat, M. A., Martin, L. M., Bhumbra, S. S., Nofziger, R. A. & Chauhan, J. C. & 17 others, , 2025, In: Morbidity and Mortality Weekly Report. 74, 37, p. 580-588 9 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Link opens in a new tab Scopus citations -
Characteristics and Clinical Outcomes of Vaccine-Eligible US Children Under-5 Years Hospitalized for Acute COVID-19 in a National Network
Zambrano, L. D., Newhams, M. M., Simeone, R. M., Fleming-Dutra, K. E., Halasa, N., Wu, M., Orzel-Lockwood, A. O., Kamidani, S., Pannaraj, P. S., Chiotos, K., Cameron, M. A., Maddux, A. B., Schuster, J. E., Crandall, H., Kong, M., Nofziger, R. A., Staat, M. A., Bhumbra, S. S., Irby, K. & Boom, J. A. & 18 others, , Mar 1 2024, In: Pediatric Infectious Disease Journal. 43, 3, p. 242-249 8 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Link opens in a new tab Scopus citations