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James R Dutton

1993 …2022
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Projects 2010 2022

Optimization of iPSC-derived oligodendrocyte progenitor cell (OPC) manufacture - A key step toward patient treatment

Dutton, J. R.

MN OFFICE OF HIGHER EDUCATION

8/13/19 → 6/30/21

Project: Research project

Oligodendroglia
Stem Cells
Therapeutics

New Combinatorial Strategies for Regenerative Repair of the Injured Spinal Cord

Dutton, J. R.

Mayo Clinic Rochester

7/2/18 → 6/30/20

Project: Research project

Spinal Cord Regeneration

A Novel Stem Cell-based Approach for Generating Non-Huma

Steer, C. J., Aravalli, R., Dutton, J. R. & Grande, A. W.

National Institutes of Health

4/2/18 → 3/31/22

Project: Research project

stem cells
Primates
liver
swine

Mitochondrial defects in the retinal pigment epithelium

Ferrington, D. A., Dutton, J. R. & Montezuma, S. R.

NIH NEI NATL EYE INST

4/1/18 → 3/31/22

Project: Research project

Retinal Pigment Epithelium
Macular Degeneration
Alleles

Multicomponent solutions for the preservation of cell th

Hubel, A., Dosa, P. I., Dutton, J. R. & McKenna, D. H.

NIH NATL INST OF BIOMEDICAL IM

8/3/17 → 4/30/20

Project: Research project

Cell- and Tissue-Based Therapy

Research Output 1993 2019

Interspecies Organogenesis for Human Transplantation

Crane, A. T., Aravalli, R. N., Asakura, A., Grande, A. W., Krishna, V. D., Carlson, D. F., Cheeran, M. C. J., Danczyk, G., Dutton, J. R., Hackett, P. B., Hu, W. S., Li, L., Lu, W. C., Miller, Z. D., O’Brien, T. D., Panoskaltsis-Mortari, A., Parr, A. M., Pearce, C., Ruiz-Estevez, M., Shiao, M. & 6 others, Sipe, C. J., Toman, N. G., Voth, J., Xie, H., Steer, C. J. & Low, W. C., Sep 1 2019, In : Cell transplantation. 28, 9-10, p. 1091-1105 15 p.

Research output: Contribution to journal › Review article

Open Access
Organogenesis
Blastocyst
Genes
Transplantation
Tissue
17 Citations (Scopus)

3D Printed Stem-Cell Derived Neural Progenitors Generate Spinal Cord Scaffolds

Joung, D., Truong, V., Neitzke, C. C., Guo, S., Walsh, P. J., Monat, J. R., Meng, F., Park, S. H., Dutton, J. R., Parr, A. M. & McAlpine, M., Sep 26 2018, In : Advanced Functional Materials. 28, 39, 1801850.

Research output: Contribution to journal › Article

spinal cord
stem cells
Neurology
Stem cells
Scaffolds
1 Citation (Scopus)

Safety and Efficacy of Rose Bengal Derivatives for Glial Scar Ablation in Chronic Spinal Cord Injury

Patil, N., Truong, V., Holmberg, M. H., Lavoie, N. S., McCoy, M. R., Dutton, J. R., Holmberg, E. G. & Parr, A. M., Aug 1 2018, In : Journal of neurotrauma. 35, 15, p. 1745-1754 10 p.

Research output: Contribution to journal › Article

Open Access
Rose Bengal
Spinal Cord Injuries
Neuroglia
Cicatrix
Safety
1 Citation (Scopus)

The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways

Su, L., Kong, X., Lim, S., Loo, S., Tan, S., Poh, K., Dutton, J., Stewart, C., Cook, S., Su, X., Ma, J., Zhang, J. & Ye, L., Nov 15 2018, In : Stem cell research & therapy. 9, 1, 1 p.

Research output: Contribution to journal › Article

Prostaglandin H2
Synthetic Prostaglandins
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
Induced Pluripotent Stem Cells
Mitogen-Activated Protein Kinase 3
20 Citations (Scopus)

Altered bioenergetics and enhanced resistance to oxidative stress in human retinal pigment epithelial cells from donors with age-related macular degeneration

Ferrington, D. A., Ebeling, M. C., Kapphahn, R. J., Terluk, M. R., Fisher, C. R., Polanco, J. R., Roehrich, H., Leary, M. M., Geng, Z., Dutton, J. R. & Montezuma, S. R., Oct 1 2017, In : Redox Biology. 13, p. 255-265 11 p.

Research output: Contribution to journal › Article

Open Access
Oxidative stress
Retinal Pigments
Retinal Pigment Epithelium
Macular Degeneration
Energy Metabolism