1978 …2024
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Research Output 1978 2020

2020

SEMA4C is a novel target to limit osteosarcoma growth, progression, and metastasis

Smeester, B. A., Slipek, N. J., Pomeroy, E. J., Bomberger, H. E., Shamsan, G. A., Peterson, J. J., Crosby, M. R., Draper, G. M., Becklin, K. L., Rahrmann, E. P., McCarthy, J. B., Odde, D. J., Wood, D. K., Largaespada, D. A. & Moriarity, B. S., Jan 30 2020, In : Oncogene. 39, 5, p. 1049-1062 14 p.

Research output: Contribution to journalArticle

Semaphorins
Osteosarcoma
Neoplasm Metastasis
Growth
Neoplasms
2019

Chondroitin sulfate proteoglycan 4 enhanced melanoma motility and growth requires a cysteine in the core protein transmembrane domain

Yang, J., Price, M. A., Wanshura, L. E. C., He, J., Yi, M., Welch, D. R., Li, G., Conner, S., Sachs, J., Turley, E. A. & McCarthy, J. B., Aug 1 2019, In : Melanoma research. 29, 4, p. 365-375 11 p.

Research output: Contribution to journalArticle

Cysteine
Melanoma
Growth
Focal Adhesion Protein-Tyrosine Kinases
Mitogen-Activated Protein Kinase 3
2018
7 Citations (Scopus)

Cellular and molecular networking within the ecosystem of cancer cell communication via tunneling nanotubes

Lou, E., Zhai, E., Sarkari, A., Desir, S., Wong, P., Iizuka, Y., Yang, J., Subramanian, S., McCarthy, J., Bazzaro, M. & Steer, C. J., Oct 2 2018, In : Frontiers in Cell and Developmental Biology. 6, OCT, 95.

Research output: Contribution to journalArticle

Open Access
Nanotubes
Cell Communication
Ecosystem
Neoplasms
Interdisciplinary Studies
3 Citations (Scopus)
Open Access
Tumor Microenvironment
Hyaluronic Acid
corrigendum
Cancer-Associated Fibroblasts
11 Citations (Scopus)
Open Access
Tumor Microenvironment
Hyaluronic Acid
Neoplasms
Extracellular Matrix
Fibrillar Collagens
1 Citation (Scopus)

In vitro elucidation of the role of pericellular matrix in metastatic extravasation and invasion of breast carcinoma cells

Brett, M. E., Bomberger, H. E., Doak, G. R., Price, M. A., McCarthy, J. B. & Wood, D. K., Apr 2018, In : Integrative Biology (United Kingdom). 10, 4, p. 242-252 11 p.

Research output: Contribution to journalArticle

Hyaluronic Acid
Cells
Breast Neoplasms
Tumors
Carcinoma
2017
21 Citations (Scopus)

Biphasic Dependence of Glioma Survival and Cell Migration on CD44 Expression Level

Klank, R. L., Decker Grunke, S. A., Bangasser, B. L., Forster, C. L., Price, M. A., Odde, T. J., SantaCruz, K. S., Rosenfeld, S. S., Canoll, P., Turley, E. A., McCarthy, J. B., Ohlfest, J. R. & Odde, D. J., Jan 3 2017, In : Cell reports. 18, 1, p. 23-31 9 p.

Research output: Contribution to journalArticle

Open Access
Bearings (structural)
Biomarkers
Glioma
Cell Movement
Brain
2 Citations (Scopus)

Erratum: Biphasic Dependence of Glioma Survival and Cell Migration on CD44 Expression Level (Cell Reports (2017) 18(1) (23–31)(S2211124716317144)(10.1016/j.celrep.2016.12.024))

Klank, R. L., Decker Grunke, S. A., Bangasser, B. L., Forster, C. L., Price, M. A., Odde, T. J., SantaCruz, K. S., Rosenfeld, S. S., Canoll, P., Turley, E. A., McCarthy, J. B., Ohlfest, J. R. & Odde, D. J., Apr 18 2017, In : Cell reports. 19, 3, 1 p.

Research output: Contribution to journalComment/debate

5-chloro-3-tert-butyl-2'-chloro-4'-nitrosalicylanilide
Glioma
Cell Movement
Emotions
15 Citations (Scopus)

Hyaluronan modulates growth factor induced mammary gland branching in a size dependent manner

Tolg, C., Yuan, H., Flynn, S. M., Basu, K., Ma, J., Tse, K. C. K., Kowalska, B., Vulkanesku, D., Cowman, M. K., McCarthy, J. B. & Turley, E. A., Nov 2017, In : Matrix Biology. 63, p. 117-132 16 p.

Research output: Contribution to journalArticle

Hyaluronic Acid
Human Mammary Glands
Intercellular Signaling Peptides and Proteins
CD44 Antigens
Morphogenesis
23 Citations (Scopus)

RB loss promotes prostate cancer metastasis

Thangavel, C., Boopathi, E., Liu, Y., Haber, A., Ertel, A., Bhardwaj, A., Addya, S., Williams, N., Ciment, S. J., Cotzia, P., Dean, J. L., Snook, A., McNair, C., Price, M., Hernandez, J. R., Zhao, S. G., Birbe, R., McCarthy, J. B., Turley, E. A., Pienta, K. J. & 4 others, Feng, F. Y., Dicker, A. P., Knudsen, K. E. & Den, R. B., Feb 15 2017, In : Cancer Research. 77, 4, p. 982-995 14 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Neoplasm Metastasis
Neoplasms
Phenotype
Critical Pathways
6 Citations (Scopus)

Receptor for hyaluronan mediated motility (RHAMM/HMMR) is a novel target for promoting subcutaneous adipogenesis

Bahrami, S. B., Tolg, C., Peart, T., Symonette, C., Veiseh, M., Umoh, J. U., Holdsworth, D. W., McCarthy, J. B., Luyt, L. G., Bissell, M. J., Yazdani, A. & Turley, E. A., Mar 2017, In : Integrative Biology (United Kingdom). 9, 3, p. 223-237 15 p.

Research output: Contribution to journalArticle

Open Access
Adipogenesis
Fats
Peptides
Subcutaneous Fat
Hyaluronic Acid
7 Citations (Scopus)

The NOR1/OSCP1 proteins in cancer: From epigenetic silencing to functional characterization of a novel tumor suppressor

Yi, M., Yang, J., Li, W., Li, X., Xiong, W., McCarthy, J. B., Li, G. & Xiang, B., Jan 1 2017, In : Journal of Cancer. 8, 4, p. 626-635 10 p.

Research output: Contribution to journalReview article

Open Access
Epigenomics
Neoplasms
Proteins
Down-Regulation
Gastropoda
2016
32 Citations (Scopus)

Carcinoma cell hyaluronan as a "portable" cancerized prometastatic microenvironment

Turley, E. A., Wood, D. K. & McCarthy, J. B., May 1 2016, In : Cancer Research. 76, 9, p. 2507-2512 6 p.

Research output: Contribution to journalReview article

Hyaluronic Acid
Carcinoma
Neoplasms
Polymers
CD44 Antigens
18 Citations (Scopus)

Significance of the NOR1-FOXA1/HDAC2-Slug regulatory network in epithelial-mesenchymal transition of tumor cells

Wang, W., Yi, M., Chen, S., Li, J., Li, G., Yang, J., Zheng, P., Zhang, H., Xiong, W., McCarthy, J. B., Li, G., Li, X. & Xiang, B., Mar 29 2016, In : Oncotarget. 7, 13, p. 16745-16759 15 p.

Research output: Contribution to journalArticle

Gastropoda
Epithelial-Mesenchymal Transition
Neoplasms
Data Mining
RNA Interference
2015
71 Citations (Scopus)

Hyaluronan, inflammation, and breast cancer progression

Schwertfeger, K. L., Cowman, M. K., Telmer, P. G., Turley, E. A. & McCarthy, J. B., Jan 1 2015, In : Frontiers in immunology. 6, JUN, 236.

Research output: Contribution to journalReview article

Hyaluronic Acid
Breast Neoplasms
Inflammation
Neoplasms
CD44 Antigens
7 Citations (Scopus)

Hyaluronan stimulates ex vivo B lymphocyte chemotaxis and cytokine production in a murine model of fungal allergic asthma

Ghosh, S., Hoselton, S. A., Wanjara, S. B., Carlson, J., McCarthy, J. B., Dorsam, G. P. & Schuh, J. M., Jul 1 2015, In : Immunobiology. 220, 7, p. 899-909 11 p.

Research output: Contribution to journalArticle

Chemotaxis
Hyaluronic Acid
B-Lymphocytes
Asthma
Cytokines
9 Citations (Scopus)

Identification, design and synthesis of tubulin-derived peptides as novel hyaluronan mimetic ligands for the receptor for hyaluronan-mediated motility (RHAMM/HMMR)

Esguerra, K. V. N., Tolg, C., Akentieva, N., Price, M. A., Cho, C. F., Lewis, J. D., Mc Carthy, J. B., Turley, E. A. & Luyt, L. G., Dec 2015, In : Integrative Biology (United Kingdom). 7, 12, p. 1547-1560 14 p.

Research output: Contribution to journalArticle

Hyaluronic Acid
Tubulin
Ligands
Peptides
Surface plasmon resonance
52 Citations (Scopus)

The content and size of hyaluronan in biological fluids and tissues

Cowman, M. K., Lee, H. G., Schwertfeger, K. L., McCarthy, J. B. & Turley, E. A., Jan 1 2015, In : Frontiers in immunology. 6, JUN, 261.

Research output: Contribution to journalReview article

Hyaluronic Acid
Polymers
Cellular Microenvironment
Disaccharides
Toll-Like Receptors
7 Citations (Scopus)

Uncovering the dual role of RHAMM as an HA receptor and a regulator of CD44 expression in RHAMM-expressing mesenchymal progenitor cells

Veiseh, M., Leith, S. J., Tolg, C., Elhayek, S. S., Bahrami, S. B., Collis, L., Hamilton, S., McCarthy, J. B., Bissell, M. J. & Turley, E., Oct 15 2015, In : Frontiers in Cell and Developmental Biology. 3, OCT, 63.

Research output: Contribution to journalArticle

Open Access
CD44 Antigens
Mesenchymal Stromal Cells
Hyaluronic Acid
Anti-Idiotypic Antibodies
Cellular Microenvironment
2014
28 Citations (Scopus)

Activation of the FGFR-STAT3 pathway in breast cancer cells induces a hyaluronan-rich microenvironment that licenses tumor formation

Bohrer, L. R., Chuntova, P., Bade, L. K., Beadnell, T. C., Leon, R. P., Brady, N. J., Ryu, Y., Goldberg, J. E., Schmechel, S. C., Koopmeiners, J. S., McCarthy, J. B. & Schwertfeger, K. L., Jan 1 2014, In : Cancer Research. 74, 1, p. 374-386 13 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor Receptors
Tumor Microenvironment
Hyaluronic Acid
Licensure
Breast Neoplasms
19 Citations (Scopus)

Elevated hyaluronan and hyaluronan-mediated motility receptor are associated with biochemical failure in patients with intermediate-grade prostate tumors

Rizzardi, A. E., Vogel, R. I., Koopmeiners, J., Forster, C. L., Marston, L. O., Rosener, N. K., Akentieva, N., Price, M. A., Metzger, G., Warlick, C. A., Henriksen, J. C., Turley, E. A., Mc Carthy, J. B. & Schmechel, S. C., Jun 15 2014, In : Cancer. 120, 12, p. 1800-1809 10 p.

Research output: Contribution to journalArticle

Hyaluronic Acid
Prostate
Neoplasms
Prostatic Neoplasms
Tumor Microenvironment
26 Citations (Scopus)

Evaluation of protein biomarkers of prostate cancer aggressiveness

Rizzardi, A. E., Rosener, N. K., Koopmeiners, J. S., Isaksson Vogel, R., Metzger, G. J., Forster, C. L., Marston, L. O., Tiffany, J. R., McCarthy, J. B., Turley, E. A., Warlick, C. A., Henriksen, J. C. & Schmechel, S. C., Apr 5 2014, In : BMC Cancer. 14, 1, 244.

Research output: Contribution to journalArticle

Biomarkers
Prostatectomy
Proteins
Prostatic Neoplasms
Epithelium
45 Citations (Scopus)

Hyaluronan and RHAMM in Wound Repair and the "cancerization" of Stromal Tissues

Tolg, C., McCarthy, J. B., Yazdani, A. & Turley, E. A., Jan 1 2014, In : BioMed Research International. 2014, 103923.

Research output: Contribution to journalReview article

Hyaluronic Acid
Tumors
Repair
Tissue
Wounds and Injuries
6 Citations (Scopus)

Isothiocyanate analogs targeting CD44 receptor as an effective strategy against colon cancer

Misra, S., Ghatak, S., Vyas, A., O'Brien, P., Markwald, R. R., Khetmalas, M., Hascall, V. C., McCarthy, J. B., Karamanos, N. K., Tammi, M. I., Tammi, R. H., Prestwitch, G. D. & Padhye, S., Aug 2014, In : Medicinal Chemistry Research. 23, 8, p. 3836-3851 16 p.

Research output: Contribution to journalArticle

Colonic Neoplasms
Cells
Colorectal Neoplasms
Isothiocyanates
Thiosemicarbazones
21 Citations (Scopus)

Oxidored-nitro domain containing protein 1 (NOR1) expression suppresses slug/vimentin but not snail in nasopharyngeal carcinoma: Inhibition of EMT in vitro and in vivo in mice

Wang, W., Li, X., Zhang, W., Li, W., Yi, M., Yang, J., Zeng, Z., Wanshura, L. E. C., Mc Carthy, J. B., Fan, S., Zheng, P., Chen, S., Xiang, B. & Li, G., Jan 1 2014, In : Cancer Letters. 348, 1-2, p. 109-118 10 p.

Research output: Contribution to journalArticle

Gastropoda
Epithelial-Mesenchymal Transition
Snails
Vimentin
HeLa Cells
2013
81 Citations (Scopus)

miR-18a promotes malignant progression by impairing microRNA biogenesis in nasopharyngeal carcinoma

Luo, Z., Dai, Y., zhang, L., Jiang, C., Li, Z., Yang, J., McCarthy, J. B., She, X., Zhang, W., Ma, J., Xiong, W., Wu, M., Lu, J., Li, X., Li, X., Xiang, J. & Li, G., Feb 1 2013, In : Carcinogenesis. 34, 2, p. 415-425 11 p.

Research output: Contribution to journalArticle

MicroRNAs
Down-Regulation
Nasopharyngeal carcinoma
Epstein-Barr Virus Infections
Epithelial-Mesenchymal Transition
21 Citations (Scopus)

SPLUNC1 Regulates Cell Progression and Apoptosis through the miR-141-PTEN/p27 Pathway, but Is Hindered by LMP1

Chen, P., Guo, X., Zhou, H., Zhang, W., Zeng, Z., Liao, Q., Li, X., Xiang, B., Yang, J., Ma, J., Zhou, M., Peng, S., Xiang, J., Li, X., Le, C. W., Xiong, W., McCarthy, J. B. & Li, G., Mar 5 2013, In : PloS one. 8, 3, e56929.

Research output: Contribution to journalArticle

Nasal Mucosa
palate
Palate
Cell proliferation
carcinoma
14 Citations (Scopus)

Tumor suppressor gene Oxidored-nitro domain-containing protein 1 regulates nasopharyngeal cancer cell autophagy, metabolism, and apoptosis in vitro

Li, W., Li, X., Wang, W., Yi, M., Zhou, Y., Zheng, P., Xiong, W., Yang, J., Peng, S., McCarthy, J. B., Xiang, B. & Li, G., Jan 1 2013, In : International Journal of Biochemistry and Cell Biology. 45, 9, p. 2016-2026 11 p.

Research output: Contribution to journalArticle

Nasopharyngeal Neoplasms
Autophagy
Tumor Suppressor Genes
Metabolism
Tumors
2012
60 Citations (Scopus)

A RHAMM mimetic peptide blocks hyaluronan signaling and reduces inflammation and fibrogenesis in excisional skin wounds

Tolg, C., Hamilton, S. R., Zalinska, E., McCulloch, L., Amin, R., Akentieva, N., Winnik, F., Savani, R., Bagli, D. J., Luyt, L. G., Cowman, M. K., McCarthy, J. B. & Turley, E. A., Oct 1 2012, In : American Journal of Pathology. 181, 4, p. 1250-1270 21 p.

Research output: Contribution to journalArticle

Hyaluronic Acid
Inflammation
Skin
Peptides
Wounds and Injuries
2011
76 Citations (Scopus)

CSPG4, a potential therapeutic target, facilitates malignant progression of melanoma

Price, M. A., Colvin Wanshura, L. E., Yang, J., Carlson, J., Xiang, B., Li, G., Ferrone, S., Dudek, A. Z., Turley, E. A. & McCarthy, J. B., Dec 1 2011, In : Pigment Cell and Melanoma Research. 24, 6, p. 1148-1157 10 p.

Research output: Contribution to journalComment/debate

Melanoma
Tumors
Integrins
Therapeutics
Neoplasms
28 Citations (Scopus)

How does a protein with dual mitotic spindle and extracellular matrix receptor functions affect tumor susceptibility and progression?

Telmer, P. G., Tolg, C., McCarthy, J. B. & Turley, E. A., Mar 1 2011, In : Communicative and Integrative Biology. 4, 2, p. 182-185 4 p.

Research output: Contribution to journalArticle

hyaluronic acid
mitotic spindle apparatus
Spindle Apparatus
extracellular matrix
CD44 Antigens
35 Citations (Scopus)

NOR1 is an HSF1- and NRF1-regulated putative tumor suppressor inactivated by promoter hypermethylation in nasopharyngeal carcinoma

Li, W., Li, X., Wang, W., Li, X., Tan, Y., Yi, M., Yang, J., McCarthy, J. B., Xiong, W., Wu, M., Ma, J., Su, B., Zhang, Z., Liao, Q., Xiang, B. & Li, G., Sep 9 2011, In : Carcinogenesis. 32, 9, p. 1305-1314 10 p.

Research output: Contribution to journalArticle

Neoplasms
CpG Islands
decitabine
Gene Silencing
Tumor Suppressor Genes
23 Citations (Scopus)

RASSF1A suppresses melanoma development by modulating apoptosis and cell-cycle progression

Yi, M., Yang, J., Chen, X., Li, J., Li, X., Wang, L., Tan, Y., Xiong, W., Zhou, M., Mccarthy, J. B., Li, G., Xiang, B. & Xie, H., Sep 1 2011, In : Journal of cellular physiology. 226, 9, p. 2360-2369 10 p.

Research output: Contribution to journalArticle

Melanoma
Cell Cycle
Protein Isoforms
Cells
Association reactions
2010
65 Citations (Scopus)

CSPG4 in cancer: Multiple roles

Wang, X., Wang, Y., Yu, L., Sakakura, K., Visus, C., Schwab, J. H., Ferrone, C. R., Favoino, E., Koya, Y., Campoli, M. R., Mc Carthy, J. B., Deleo, A. B. & Ferrone, S., Jun 18 2010, In : Current Molecular Medicine. 10, 4, p. 419-429 11 p.

Research output: Contribution to journalArticle

Tumors
Neoplasms
Monoclonal Antibodies
Cells
Neoplastic Stem Cells
90 Citations (Scopus)

CSPG4 protein as a new target for the antibody-based immunotherapy of triple-negative breast cancer

Wang, X., Osada, T., Wang, Y., Yu, L., Sakakura, K., Katayama, A., McCarthy, J. B., Brufsky, A., Chivukula, M., Khoury, T., Hsu, D. S., Barry, W. T., Lyerly, H. K., Clay, T. M. & Ferrone, S., Oct 6 2010, In : Journal of the National Cancer Institute. 102, 19, p. 1496-1512 17 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Immunotherapy
Monoclonal Antibodies
Antibodies
Neoplasm Metastasis

Erratum: Cyclin D1 promotes anchorage-independent cell survival by inhibiting FOXO-mediated anoikis (Cell Death and Differentiation (2009) 16 (1408-1417) DOI: 10.1038/cdd.2009.86))

Gan, L., Liu, P., Lu, H., Chen, S., Yang, J., McCarthy, J. B., Knudsen, K. E. & Huang, H., May 1 2010, In : Cell Death and Differentiation. 17, 5, 1 p.

Research output: Contribution to journalComment/debate

Anoikis
Cyclin D1
Cell Differentiation
Cell Survival
Cell Death
55 Citations (Scopus)

RHAMM promotes interphase microtubule instability and mitotic spindle integrity through MEK1/ERK1/2 activity

Tolg, C., Hamilton, S. R., Morningstar, L., Zhang, J., Zhang, S., Esguerra, K. V., Telmer, P. G., Luyt, L. G., Harrison, R., McCarthy, J. B. & Turley, E. A., Aug 20 2010, In : Journal of Biological Chemistry. 285, 34, p. 26461-26474 14 p.

Research output: Contribution to journalArticle

Spindle Apparatus
Interphase
Tubulin
Microtubules
Fibroblasts
2009
22 Citations (Scopus)

Cyclin D1 promotes anchorage-independent cell survival by inhibiting FOXO-mediated anoikis

Gan, L., Liu, P., Chen, S., Yang, J., Mc Carthy, J. B., Knudsen, K. E. & Huang, H., Jan 1 2009, In : Cell Death and Differentiation. 16, 10, p. 1408-1417 10 p.

Research output: Contribution to journalArticle

Anoikis
Cyclin D1
Cell Survival
Neoplasms
Neoplasm Metastasis
13 Citations (Scopus)

Inhibition of hyaluronan synthases decreases matrix metalloproteinase-7 (MMP-7) expression and activity

Bullard Dunn, K. M., Lee, P. K., Wilson, C. M., Iida, J., Wasiluk, K. R., Hugger, M. & McCarthy, J. B., Mar 1 2009, In : Surgery. 145, 3, p. 322-329 8 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 7
Matrix Metalloproteinases
Hyaluronic Acid
Isoenzymes
Colon
51 Citations (Scopus)

Melanoma proteoglycan modifies gene expression to stimulate tumor cell motility, growth, and epithelial-to-mesenchymal transition

Yang, J., Price, M. A., Gui, Y. L., Bar-Eli, M., Salgia, R., Jagedeeswaran, R., Carlson, J. H., Ferrone, S., Turley, E. A. & McCarthy, J. B., Oct 1 2009, In : Cancer Research. 69, 19, p. 7538-7547 10 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Chondroitin Sulfate Proteoglycans
Proteoglycans
Cell Movement
Melanoma

RHAMM/HMMR: An Itinerant and Multifunctional Hyaluronan Binding Protein That Modifies CD44 Signaling and Mitotic Spindle Formation

Mc Carthy, J. B. & Turley, E. A., Dec 1 2009, Hyaluronan in Cancer Biology. Elsevier Inc., p. 147-168 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

CD44 Antigens
Spindle Apparatus
Tumors
Growth Factor Receptors
Pathology
2008
144 Citations (Scopus)

Cell-surface and mitotic-spindle RHAMM: Moonlighting or dual oncogenic functions?

Maxwell, C. A., McCarthy, J. & Turley, E., Apr 1 2008, In : Journal of cell science. 121, 7, p. 925-932 8 p.

Research output: Contribution to journalArticle

Spindle Apparatus
Neoplasms
Proteins
CD44 Antigens
Fibroblast Growth Factor 1
2 Citations (Scopus)

The effect of a hyaluronan-carboxymethylcellulose membrane vs. polyglactin 910 mesh on intra-abdominal tumor formation in mice

Lee, P. K., Windsperger, A. P., Wilson, C. M., McCarthy, J. B., Wasiluk, K. R., Rothenberger, D. A. & Bullard Dunn, K. M., Sep 1 2008, In : Diseases of the Colon and Rectum. 51, 9, p. 1403-1407 5 p.

Research output: Contribution to journalArticle

Polyglactin 910
Carboxymethylcellulose Sodium
Hyaluronic Acid
Membranes
Neoplasms
2007
83 Citations (Scopus)

Cell surface chondroitin sulfate glycosaminoglycan in melanoma: Role in the activation of pro-MMP-2 (pro-gelatinase A)

Iida, J., Wilhelmson, K. L., Ng, J., Lee, P., Morrison, C., Tam, E., Overall, C. M. & McCarthy, J. B., May 1 2007, In : Biochemical Journal. 403, 3, p. 553-563 11 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 16
Matrix Metalloproteinase 2
Melanoma
Chondroitin Sulfates
Chemical activation
32 Citations (Scopus)

Expression of collagenase-1 (MMP-1) promotes melanoma growth through the generation of active transforming growth factor-β

Iida, J. & McCarthy, J. B., Aug 1 2007, In : Melanoma Research. 17, 4, p. 205-213 9 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 1
Transforming Growth Factors
Melanoma
Growth
Growth Factor Receptors
1 Citation (Scopus)
Syntenins
PDZ Domains
Melanoma
Neoplasm Metastasis
Proteins
173 Citations (Scopus)

The hyaluronan receptors CD44 and Rhamm (CD168) form complexes with ERK1,2 that sustain high basal motility in breast cancer cells

Hamilton, S. R., Fard, S. F., Paiwand, F. F., Tolg, C., Veiseh, M., Wang, C., McCarthy, J. B., Bissell, M. J., Koropatnick, J. & Turley, E. A., Jun 1 2007, In : Journal of Biological Chemistry. 282, 22, p. 16667-16680 14 p.

Research output: Contribution to journalArticle

CD44 Antigens
Cells
Breast Neoplasms
Hyaluronic Acid
Tumors
2006
98 Citations (Scopus)

Effect of RGD secondary structure and the synergy site PHSRN on cell adhesion, spreading and specific integrin engagement

Ochsenhirt, S. E., Kokkoli, E., Mc Carthy, J. B. & Tirrell, M., Jul 1 2006, In : Biomaterials. 27, 20, p. 3863-3874 12 p.

Research output: Contribution to journalArticle

prolyl-histidyl-seryl-arginyl-asparagine
glycyl-arginyl-glycyl-aspartyl-seryl-proline
Cell adhesion
Amphiphiles
Cell Adhesion
32 Citations (Scopus)

Membrane ganglioside enrichment lowers the threshold for vascular endothelial cell angiogenic signaling

Liu, Y., McCarthy, J. & Ladisch, S., Nov 1 2006, In : Cancer Research. 66, 21, p. 10408-10414 7 p.

Research output: Contribution to journalArticle

Gangliosides
Endothelial Cells
Membranes
Vascular Endothelial Growth Factor A
Neoplasms
96 Citations (Scopus)

Rhamm-/- fibroblasts are defective in CD44-mediated ERK1,2 motogenic signaling, leading to defective skin wound repair

Tolg, C., Hamilton, S. R., Nakrieko, K. A., Kooshesh, F., Walton, P., McCarthy, J. B., Bissell, M. J. & Turley, E. A., Dec 18 2006, In : Journal of Cell Biology. 175, 6, p. 1017-1028 12 p.

Research output: Contribution to journalArticle

Fibroblasts
Skin
Wounds and Injuries
Phosphotransferases
Hyaluronic Acid