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Research Output 1996 2019

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Article
2019

Intrathecal enzyme replacement for Hurler syndrome: biomarker association with neurocognitive outcomes

Eisengart, J., Pierpont, R., Kaizer, A. M., Rudser, K., King, K. E., Pasquali, M., Polgreen, L. E., Dickson, P. I., Le, S. Q., Miller, W. P., Tolar, J., Orchard, P. J. & Lund, T. C., Jan 1 2019, In : Genetics in Medicine.

Research output: Contribution to journalArticle

Open Access
Mucopolysaccharidosis I
Enzyme Replacement Therapy
Biomarkers
Cerebrospinal Fluid
Enzymes
1 Citation (Scopus)
Clustered Regularly Interspaced Short Palindromic Repeats
Induced Pluripotent Stem Cells
Transcription
Fibroblasts
Stem cells
2018
13 Citations (Scopus)

3D Printed Functional and Biological Materials on Moving Freeform Surfaces

Zhu, Z., Guo, S., Hirdler, T., Eide, C., Fan, X., Tolar, J. & McAlpine, M., Jun 6 2018, In : Advanced Materials. 30, 23, 1707495.

Research output: Contribution to journalArticle

Open Access
Functional materials
Biological materials
Printing
Hydrogels
Real time control

A 3D in vitro model of the dermoepidermal junction amenable to mechanical testing

Jung, J. P., Lin, W. H., Riddle, M. J., Tolar, J. & Ogle, B. M., Dec 1 2018, In : Journal of Biomedical Materials Research - Part A. 106, 12, p. 3231-3238 8 p.

Research output: Contribution to journalArticle

Open Access
Mechanical testing
Fibroblasts
Collagen Type VII
Adhesion
Collagen
3 Citations (Scopus)

A multitask clustering approach for single-cell RNA-seq analysis in Recessive Dystrophic Epidermolysis Bullosa

Zhang, H., Lee, C. A. A., Li, Z., Garbe, J. R., Eide, C. R., Petegrosso, R., Kuang, R. & Tolar, J., Apr 1 2018, In : PLoS Computational Biology. 14, 4, e1006053.

Research output: Contribution to journalArticle

Open Access
epidermolysis bullosa
Epidermolysis Bullosa Dystrophica
RNA
Cluster Analysis
Clustering
5 Citations (Scopus)

ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism

Rousseaux, M. W. C., Tschumperlin, T., Lu, H. C., Lackey, E. P., Bondar, V. V., Wan, Y. W., Tan, Q., Adamski, C. J., Friedrich, J., Twaroski, K., Chen, W., Tolar, J., Henzler, C., Sharma, A., Bajić, A., Lin, T., Duvick, L., Liu, Z., Sillitoe, R. V., Zoghbi, H. Y. & 1 othersOrr, H. T., Mar 21 2018, In : Neuron. 97, 6, p. 1235-1243.e5

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Pathology
Cerebellum
Neurons
Purkinje Cells
13 Citations (Scopus)

Continuous treatment with IL-15 exhausts human NK cells via a metabolic defect

Felices, M., Lenvik, A. J., Mc Elmurry, R. T., Chu, S., Hinderlie, P., Bendzick, L., Geller, M. A., Tolar, J., Blazar, B. R. & Miller, J. S., Feb 8 2018, In : JCI insight. 3, 3

Research output: Contribution to journalArticle

Open Access
Interleukin-15
Natural Killer Cells
Therapeutics
cdc Genes
Fatty Acids
4 Citations (Scopus)

Crispr/cas9-based cellular engineering for targeted gene overexpression

Osborn, M. J., Lees, C. J., McElroy, A. N., Merkel, S. C., Eide, C. R., Mathews, W. E., Feser, C. J., Tschann, M., Mc Elmurry, R. T., Webber, B. R., Kim, C. J., Blazar, B. R. & Tolar, J., Apr 1 2018, In : International journal of molecular sciences. 19, 4, 946.

Research output: Contribution to journalArticle

Cell Engineering
genes
Genes
engineering
T-cells
5 Citations (Scopus)

Human CD19-Targeted Mouse T Cells Induce B Cell Aplasia and Toxicity in Human CD19 Transgenic Mice

Pennell, C. A., Barnum, J. L., McDonald-Hyman, C. S., Panoskaltsis-Mortari, A., Riddle, M. J., Xiong, Z., Loschi, M., Thangavelu, G., Campbell, H. M., Storlie, M. D., Refaeli, Y., Furlan, S. N., Jensen, M. C., Kean, L. S., Miller, J. S., Tolar, J., Osborn, M. J. & Blazar, B. R., Jun 6 2018, In : Molecular Therapy. 26, 6, p. 1423-1434 12 p.

Research output: Contribution to journalArticle

Transgenic Mice
B-Lymphocytes
T-Lymphocytes
T-Cell Antigen Receptor
Antigen Receptors
5 Citations (Scopus)
Open Access
Adrenoleukodystrophy
Blood-Brain Barrier
Endothelial Cells
Brain
Ethylene Oxide

Montagna Symposium 2017—Precision Dermatology: Next Generation Prevention, Diagnosis, and Treatment

Tolar, J., Bauer, J. W., Kaplan, D. H., Leachman, S. A., McGrath, J. A., Paller, A. S., Griffith-Bauer, K. A., Stemwedel, C. E. & Kulesz-Martin, M. F., Jun 1 2018, In : Journal of Investigative Dermatology. 138, 6, p. 1243-1248 6 p.

Research output: Contribution to journalArticle

Precision Medicine
Dermatology
Genomics
Skin Diseases
Biomedical Research
5 Citations (Scopus)

Murine chronic graft-versus-host disease proteome profiling discovers CCL15 as a novel biomarker in patients

Du, J., Flynn, R. P., Paz, K., Ren, H. G., Ogata, Y., Zhang, Q., Gafken, P. R., Storer, B. E., Roy, N. H., Burkhardt, J. K., Mathews, W. E., Tolar, J., Lee, S. J., Blazar, B. R. & Paczesny, S., Apr 12 2018, In : Blood. 131, 15, p. 1743-1754 12 p.

Research output: Contribution to journalArticle

Open Access
Biomarkers
Graft vs Host Disease
Proteome
Grafts
T-cells
5 Citations (Scopus)

Outcome of haematopoietic stem cell transplantation in dyskeratosis congenita

Fioredda, F., Iacobelli, S., Korthof, E. T., Knol, C., van Biezen, A., Bresters, D., Veys, P., Yoshimi, A., Fagioli, F., Mats, B., Zecca, M., Faraci, M., Miano, M., Arcuri, L., Maschan, M., O'Brien, T., Diaz, M. A., Sevilla, J., Smith, O., Peffault de Latour, R. & 13 othersde la Fuente, J., Or, R., Van Lint, M. T., Tolar, J., Aljurf, M., Fisher, A., Skorobogatova, E. V., Diaz de Heredia, C., Risitano, A., Dalle, J. H., Sedláček, P., Ghavamzadeh, A. & Dufour, C., Oct 1 2018, In : British Journal of Haematology. 183, 1, p. 110-118 9 p.

Research output: Contribution to journalArticle

Dyskeratosis Congenita
Hematopoietic Stem Cell Transplantation
Disease-Free Survival
Bone Marrow
Inborn Genetic Diseases
1 Citation (Scopus)

Regenerative Solutions for Inherited Diseases

Tolar, J., May 1 2018, In : Clinical pharmacology and therapeutics. 103, 5, p. 763-766 4 p.

Research output: Contribution to journalArticle

Inborn Genetic Diseases
Regenerative Medicine
Computational Biology
Health
Therapeutics
3 Citations (Scopus)

Reliability and validity of the instrument for scoring clinical outcomes of research for epidermolysis bullosa (iscorEB)

Bruckner, A. L., Fairclough, D. L., Feinstein, J. A., Lara-Corrales, I., Lucky, A. W., Tolar, J. & Pope, E., May 1 2018, In : British Journal of Dermatology. 178, 5, p. 1128-1134 7 p.

Research output: Contribution to journalArticle

Epidermolysis Bullosa
Reproducibility of Results
Outcome Assessment (Health Care)
Quality of Life
Epidermolysis Bullosa Dystrophica

Thymic epithelial cell support of thymopoiesis does not require Klotho

Xing, Y., Smith, M. J., Goetz, C. A., Mc Elmurry, R. T., Parker, S. L., Min, D., Hollander, G. A., Weinberg, K. I., Tolar, J., Stefanski, H. E. & Blazar, B. R., Dec 1 2018, In : Journal of Immunology. 201, 11, p. 3320-3328 9 p.

Research output: Contribution to journalArticle

Open Access
Vitamin D
Epithelial Cells
Thymus Gland
T-Lymphocytes
Thymocytes
2017
2 Citations (Scopus)

Abnormal polyamine metabolism is unique to the neuropathic forms of MPS: Potential for biomarker development and insight into pathogenesis

Hinderer, C., Katz, N., Louboutin, J. P., Bell, P., Tolar, J., Orchard, P. J., Lund, T. C., Nayal, M., Weng, L., Mesaros, C., de Souza, C. F. M., Corte, A. D., Giugliani, R. & Wilson, J. M., Oct 1 2017, In : Human molecular genetics. 26, 19, p. 3837-3849 13 p.

Research output: Contribution to journalArticle

Open Access
Mucopolysaccharidoses
Polyamines
Spermine
Mucopolysaccharidosis I
Biomarkers
5 Citations (Scopus)

A Functional Bioluminescent Zebrafish Screen for Enhancing Hematopoietic Cell Homing

Astuti, Y., Kramer, A. C., Blake, A. L., Blazar, B. R., Tolar, J., Taisto, M. E. & Lund, T. C., Jan 10 2017, In : Stem Cell Reports. 8, 1, p. 177-190 14 p.

Research output: Contribution to journalArticle

Open Access
Bioluminescence
Zebrafish
Ergosterol
Imaging techniques
Firefly Luciferases
4 Citations (Scopus)

Angiotensin receptor blockade mediated amelioration of mucopolysaccharidosis type I cardiac and craniofacial pathology

Osborn, M. J., Webber, B. R., Mc Elmurry, R. T., Rudser, K., DeFeo, A. P., Muradian, M., Petryk, A., Hallgrimsson, B., Blazar, B. R., Tolar, J. & Braunlin, E. A., Mar 1 2017, In : Journal of Inherited Metabolic Disease. 40, 2, p. 281-289 9 p.

Research output: Contribution to journalArticle

Iduronidase
Mucopolysaccharidosis I
Angiotensin Receptors
Renin-Angiotensin System
Pathology
9 Citations (Scopus)

CRISPR/Cas9-mediated correction of the FANCD1 Gene in primary patient cells

Skvarova Kramarzova, K., Osborn, M. J., Webber, B. R., DeFeo, A. P., McElroy, A. N., Kim, C. J. & Tolar, J., Jun 14 2017, In : International Journal of Molecular Sciences. 18, 6, 1269.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
anemias
Fanconi Anemia
genes
Genes
13 Citations (Scopus)

Current Knowledge and Priorities for Future Research in Late Effects after Hematopoietic Cell Transplantation for Inherited Bone Marrow Failure Syndromes: Consensus Statement from the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects after Pediatric Hematopoietic Cell Transplantation

Dietz, A. C., Mehta, P. A., Vlachos, A., Savage, S. A., Bresters, D., Tolar, J., Boulad, F., Dalle, J. H., Bonfim, C., de la Fuente, J., Duncan, C. N., Baker, K. S., Pulsipher, M. A., Lipton, J. M., Wagner, J. E. & Alter, B. P., May 1 2017, In : Biology of Blood and Marrow Transplantation. 23, 5, p. 726-735 10 p.

Research output: Contribution to journalArticle

Open Access
Cell Transplantation
Fanconi Anemia
Bone Marrow
Pediatrics
Transplants
9 Citations (Scopus)

Genome-wide Specificity of Highly Efficient TALENs and CRISPR/Cas9 for T Cell Receptor Modification

Knipping, F., Osborn, M. J., Petri, K., Tolar, J., Glimm, H., von Kalle, C., Schmidt, M. & Gabriel, R., Mar 17 2017, In : Molecular Therapy - Methods and Clinical Development. 4, p. 213-224 12 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
T-Cell Antigen Receptor
Genome
Guide RNA
Integrases
4 Citations (Scopus)

Heparin Enhances Transfection in Concert with a Trehalose-Based Polycation with Challenging Cell Types

Boyle, W. S., Senger, K., Tolar, J. & Reineke, T. M., Jan 9 2017, In : Biomacromolecules. 18, 1, p. 56-67 12 p.

Research output: Contribution to journalArticle

Trehalose
Heparin
A73025
Fibroblasts
polycations
9 Citations (Scopus)

Large Intragenic Deletion in DSTYK Underlies Autosomal-Recessive Complicated Spastic Paraparesis, SPG23

Lee, J. Y. W., Hsu, C. K., Michael, M., Nanda, A., Liu, L., McMillan, J. R., Pourreyron, C., Takeichi, T., Tolar, J., Reid, E., Hayday, T., Blumen, S. C., Abu-Mouch, S., Straussberg, R., Basel-Vanagaite, L., Barhum, Y., Zouabi, Y., Al-Ajmi, H., Huang, H. Y., Lin, T. C. & 6 othersAkiyama, M., Lee, J. Y. Y., McLean, W. H. I., Simpson, M. A., Parsons, M. & McGrath, J. A., Feb 2 2017, In : American Journal of Human Genetics. 100, 2, p. 364-370 7 p.

Research output: Contribution to journalArticle

Open Access
Spastic Paraparesis
Protein-Serine-Threonine Kinases
Protein-Tyrosine Kinases
Pedigree
Keratinocytes
6 Citations (Scopus)

Late Effects Screening Guidelines after Hematopoietic Cell Transplantation for Inherited Bone Marrow Failure Syndromes: Consensus Statement From the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects After Pediatric HCT

Dietz, A. C., Savage, S. A., Vlachos, A., Mehta, P. A., Bresters, D., Tolar, J., Bonfim, C., Dalle, J. H., de la Fuente, J., Skinner, R., Boulad, F., Duncan, C. N., Baker, K. S., Pulsipher, M. A., Lipton, J. M., Wagner, J. E. & Alter, B. P., Sep 1 2017, In : Biology of Blood and Marrow Transplantation. 23, 9, p. 1422-1428 7 p.

Research output: Contribution to journalArticle

Open Access
Cell Transplantation
Bone Marrow
Guidelines
Pediatrics
Transplants
1 Citation (Scopus)
Cell Transplantation
Prospective Studies
Transplants
Adrenoleukodystrophy
Busulfan
11 Citations (Scopus)

PAX7 Targets, CD54, Integrin α9β1, and SDC2, Allow Isolation of Human ESC/iPSC-Derived Myogenic Progenitors

Magli, A., Incitti, T., Kiley, J., Swanson, S. A., Darabi, R., Rinaldi, F., Selvaraj, S., Yamamoto, A., Tolar, J., Yuan, C., Stewart, R., Thomson, J. A. & Perlingeiro, R. C. R., Jun 27 2017, In : Cell Reports. 19, 13, p. 2867-2877 11 p.

Research output: Contribution to journalArticle

Stem cells
Integrins
Muscle
Pluripotent Stem Cells
Muscles
5 Citations (Scopus)

Pharmacokinetics and Model-Based Dosing to Optimize Fludarabine Therapy in Pediatric Hematopoietic Cell Transplant Recipients

Ivaturi, V., Dvorak, C. C., Chan, D., Liu, T., Cowan, M. J., Wahlstrom, J., Stricherz, M., Jennissen, C., Orchard, P. J., Tolar, J., Pai, S. Y., Huang, L., Aweeka, F. & Long-Boyle, J., Oct 1 2017, In : Biology of Blood and Marrow Transplantation. 23, 10, p. 1701-1713 13 p.

Research output: Contribution to journalArticle

Open Access
Pharmacokinetics
Pediatrics
Transplants
Cell Transplantation
Therapeutics
11 Citations (Scopus)

Rapid DNA replication origin licensing protects stem cell pluripotency

Matson, J. P., Dumitru, R., Coryell, P., Baxley, R. M., Chen, W., Twaroski, K., Webber, B. R., Tolar, J., Bielinsky, A. K., Purvis, J. E. & Cook, J. G., Nov 17 2017, In : eLife. 6, e30473.

Research output: Contribution to journalArticle

Replication Origin
Licensure
Stem cells
DNA Replication
Stem Cells
5 Citations (Scopus)

Rapid generation of Col7a1 mouse model of recessive dystrophic epidermolysis bullosa and partial rescue via immunosuppressive dermal mesenchymal stem cells

Webber, B. R., O'Connor, K. T., Mc Elmurry, R. T., Durgin, E. N., Eide, C. R., Lees, C. J., Riddle, M. J., Mathews, W. E., Frank, N. Y., Kluth, M. A., Ganss, C., Moriarity, B. S., Frank, M. H., Osborn, M. J. & Tolar, J., Oct 1 2017, In : Laboratory Investigation. 97, 10, p. 1218-1224 7 p.

Research output: Contribution to journalArticle

Open Access
Epidermolysis Bullosa Dystrophica
Immunosuppressive Agents
Mesenchymal Stromal Cells
Skin
Clustered Regularly Interspaced Short Palindromic Repeats
3 Citations (Scopus)

T cell progenitor therapy-facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction

Smith, M. J., Reichenbach, D. K., Parker, S. L., Riddle, M. J., Mitchell, J., Osum, K. C., Mohtashami, M., Stefanski, H. E., Fife, B. T., Bhandoola, A., Hogquist, K. A., Holländer, G. A., Zúñiga-Pflücker, J. C., Tolar, J. & Blazar, B. R., May 18 2017, In : JCI insight. 2, 10

Research output: Contribution to journalArticle

Open Access
Cell- and Tissue-Based Therapy
Epithelial Cells
T-Lymphocytes
Thymus Gland
Thymocytes
1 Citation (Scopus)

TP53 Modulates Oxidative Stress in Gata1+ Erythroid Cells

Kramer, A. C., Weber, J., Zhang, Y., Tolar, J., Gibbens, Y. Y., Shevik, M. & Lund, T. C., Feb 14 2017, In : Stem Cell Reports. 8, 2, p. 360-372 13 p.

Research output: Contribution to journalArticle

Erythroid Cells
Oxidative stress
Oxidative Stress
Reactive Oxygen Species
Zebrafish
2016
1 Citation (Scopus)

A novel explanation of corneal clouding in a bone marrow transplant-treated patient with Hurler syndrome

Yuan, C., Bothun, E. D., Hardten, D. R., Tolar, J. & McLoon, L. K., Jul 1 2016, In : Experimental Eye Research. 148, p. 83-89 7 p.

Research output: Contribution to journalArticle

Mucopolysaccharidosis I
Cornea
Bone Marrow
Transplants
Collagen
2 Citations (Scopus)
Metachromatic Leukodystrophy
Cytokines
Sulfoglycosphingolipids
Lysosomal Storage Diseases
Interleukin 1 Receptor Antagonist Protein
14 Citations (Scopus)

CRISPR/Cas9 targeted gene editing and cellular engineering in fanconi anemia

Osborn, M. J., Lonetree, C. L., Webber, B. R., Patel, D. D., Dunmire, S., DeFeo, A. P., McElroy, A. N., MacMillan, M. L., Wagner, J. E., Blazar, B. R. & Tolar, J., Oct 15 2016, In : Stem Cells and Development. 25, 20, p. 1591-1603 13 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Cell Engineering
Fanconi Anemia
Induced Pluripotent Stem Cells
Genes
26 Citations (Scopus)

Enzyme replacement therapy prior to haematopoietic stem cell transplantation in Mucopolysaccharidosis Type I: 10 year combined experience of 2 centres

Ghosh, A., Miller, W., Orchard, P. J., Jones, S. A., Mercer, J., Church, H. J., Tylee, K., Lund, T., Bigger, B. W., Tolar, J. & Wynn, R. F., Mar 1 2016, In : Molecular Genetics and Metabolism. 117, 3, p. 373-377 5 p.

Research output: Contribution to journalArticle

Mucopolysaccharidosis I
Enzyme Replacement Therapy
Transplants
Hematopoietic Stem Cell Transplantation
Stem cells
53 Citations (Scopus)

Evaluation of TCR gene editing achieved by TALENs, CRISPR/Cas9, and megaTAL nucleases

Osborn, M. J., Webber, B. R., Knipping, F., Lonetree, C. L., Tennis, N., DeFeo, A. P., McElroy, A. N., Starker, C. G., Lee, C., Merkel, S., Lund, T. C., Kelly-Spratt, K. S., Jensen, M. C., Voytas, D. F., Von Kalle, C., Schmidt, M., Gabriel, R., Hippen, K. L., Miller, J. S., Scharenberg, A. M. & 2 othersTolar, J. & Blazar, B. R., Mar 1 2016, In : Molecular Therapy. 24, 3, p. 570-581 12 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
T-Lymphocytes
T-Cell Antigen Receptor
Adoptive Immunotherapy
Neoplasm Antigens
2 Citations (Scopus)

Fast, Efficient, and Gentle Transfection of Human Adherent Cells in Suspension

Agrawal, P., Ingle, N. P., Boyle, W. S., Ward, E., Tolar, J., Dorfman, K. D. & Reineke, T. M., Apr 27 2016, In : ACS Applied Materials and Interfaces. 8, 14, p. 8870-8874 5 p.

Research output: Contribution to journalArticle

Suspensions
Genes
Cells
Gene transfer
Physiology
12 Citations (Scopus)

GSK3β inhibition activates the CDX/HOX pathway and promotes hemogenic endothelial progenitor differentiation from human pluripotent stem cells

Kitajima, K., Nakajima, M., Kanokoda, M., Kyba, M., Dandapat, A., Tolar, J., Saito, M. K., Toyoda, M., Umezawa, A. & Hara, T., Jan 1 2016, In : Experimental Hematology. 44, 1, p. 68-74.e10

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Pluripotent Stem Cells
Endothelial Cells
Cell Differentiation
Mesoderm
64 Citations (Scopus)
Interleukin-15
Natural Killer Cells
Antigens
Cell Degranulation
Survival
2 Citations (Scopus)

miR-29 Regulates Type VII Collagen in Recessive Dystrophic Epidermolysis Bullosa

Vanden Oever, M. J., Muldoon, D., Mathews, W. E., Mc Elmurry, R. T. & Tolar, J., Oct 1 2016, In : Journal of Investigative Dermatology. 136, 10, p. 2013-2021 9 p.

Research output: Contribution to journalArticle

Collagen Type VII
Epidermolysis Bullosa Dystrophica
MicroRNAs
Transforming Growth Factors
Skin
102 Citations (Scopus)

Phase I/II Trial of StemRegenin-1 Expanded Umbilical Cord Blood Hematopoietic Stem Cells Supports Testing as a Stand-Alone Graft

Wagner, J. E., Brunstein, C. G., Boitano, A. E., Defor, T. E., McKenna, D., Sumstad, D., Blazar, B. R., Tolar, J., Le, C., Jones, J., Cooke, M. P. & Bleul, C. C., Jan 7 2016, In : Cell Stem Cell. 18, 1, p. 144-155 12 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Fetal Blood
Transplants
Aryl Hydrocarbon Receptors
Hematopoietic Stem Cell Transplantation
6 Citations (Scopus)

Preclinical Testing of Antihuman CD28 Fab′ Antibody in a Novel Nonhuman Primate Small Animal Rodent Model of Xenogenic Graft-Versus-Host Disease

Hippen, K. L., Watkins, B., Tkachev, V., Lemire, A. M., Lehnen, C., Riddle, M. J., Singh, K., Panoskaltsis-Mortari, A., Vanhove, B., Tolar, J., Kean, L. S. & Blazar, B. R., Dec 1 2016, In : Transplantation. 100, 12, p. 2630-2639 10 p.

Research output: Contribution to journalArticle

Graft vs Host Disease
Primates
Rodentia
Animal Models
Antibodies
26 Citations (Scopus)

Rapid induction of cerebral organoids from human induced pluripotent stem cells using a chemically defined hydrogel and defined cell culture medium

Lindborg, B. A., Brekke, J. H., Vegoe, A. L., Ulrich, C. B., Haider, K. T., Subramaniam, S., Venhuizen, S. L., Eide, C. R., Orchard, P. J., Chen, W., Wang, Q., Pelaez, F., Scott, C. M., Kokkoli, E., Keirstead, S. A., Dutton, J. R., Tolar, J. & O’Brien, T. D., Jan 1 2016, In : Stem Cells Translational Medicine. 5, 7, p. 970-979 10 p.

Research output: Contribution to journalArticle

Organoids
Induced Pluripotent Stem Cells
Hydrogel
Culture Media
Cell Culture Techniques
3 Citations (Scopus)

Toxic epidermal necrolysis in recessive dystrophic epidermolysis bullosa following bone marrow transplantation

Boull, C. L., Hylwa, S. A., Sajic, D., Wagner, J. E., Tolar, J. & Hook, K. P., Jun 1 2016, In : Journal of Pediatrics. 173, p. 242-244 3 p.

Research output: Contribution to journalArticle

Epidermolysis Bullosa Dystrophica
Stevens-Johnson Syndrome
Bone Marrow Transplantation
Epidermolysis Bullosa
Re-Epithelialization
2015
8 Citations (Scopus)

A biologic Velcro patch

Tolar, J. & Wagner, J. E., Jan 22 2015, In : New England Journal of Medicine. 372, 4, p. 382-384 3 p.

Research output: Contribution to journalArticle

Collagen Type VII
Epidermolysis Bullosa Dystrophica
Induced Pluripotent Stem Cells
Combined Modality Therapy
Skin Transplantation
3 Citations (Scopus)
Cell Transplantation
Haplotypes
Tissue Donors
Confidence Intervals
Siblings
5 Citations (Scopus)
Germ Cell and Embryonal Neoplasms
MicroRNAs
Methylation
Histology
Stem Cells
31 Citations (Scopus)

Cyclophosphamide conditioning in patients with severe aplastic anaemia given unrelated marrow transplantation: A phase 1-2 dose de-escalation study

Anderlini, P., Wu, J., Gersten, I., Ewell, M., Tolar, J., Antin, J. H., Adams, R., Arai, S., Eames, G., Horwitz, M. E., McCarty, J., Nakamura, R., Pulsipher, M. A., Rowley, S., Leifer, E., Carter, S. L., DiFronzo, N. L., Horowitz, M. M., Confer, D., Deeg, H. J. & 1 othersEapen, M., Jan 1 2015, In : The Lancet Haematology. 2, 9, p. e367-e375

Research output: Contribution to journalArticle

Aplastic Anemia
Cyclophosphamide
Transplantation
Bone Marrow
Transplants