Personal profile
Education/Academic qualification
PhD, Molecular, Cellular & Developmental Biology and Genetics, University of Minnesota
Sep 1 1992 → Dec 31 1996
Award Date: Dec 31 1996
MD, Charles University
Sep 1 1984 → Sep 27 1990
Award Date: Sep 27 1990
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 4 Quality Education -
SDG 5 Gender Equality -
SDG 7 Affordable and Clean Energy -
SDG 9 Industry, Innovation, and Infrastructure -
SDG 10 Reduced Inequalities -
SDG 16 Peace, Justice and Strong Institutions
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Collaborations and top research areas from the last five years
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Skin-targeted Cell Therapy for Recessive Dystrophic Epidermolysis Bullosa
Cui, T. (PI), Reineke, T. M. (PI), Tolar, J. (PI), Blazar, B. R. (CoI), Osborn, M. J. (Co-Principal Investigator), McElroy, A. N. (Other Role), Panda, S. (Other Role), Riddle, M. J. (Other Role) & Zhou, P. (Other Role)
NIH NIAMS NATIONALL INSTITUTE OF ARTHRIT
9/8/25 → 8/31/30
Project: Research project
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Off-the-Shelf Immune Effector Cells for Hematological Malignancies
Blazar, B. R. (PI), Felices, M. (PI), Luo, X. (PI), Miller, J. S. (PI), Osborn, M. J. (PI), Rao, J. S. (PI), Wagner, J. E. (PI), Bachanova, V. (CoI), Betts, B. (CoI), Brunstein, C. G. (CoI), Cichocki, F. M. (CoI), De For, T. E. (CoI), Eaton, A. (CoI), Hippen, K. L. (CoI), Maakaron, J. (CoI), McKenna, D. H. (CoI), Shanley, R. M. (CoI), Tolar, J. (CoI), Zaiken, M. C. (CoI), Dougherty, P. R. (Graduate Student), Peng, Y. (Graduate Student), Le, C. T. (Prior Principal Investigator), Braun, J. A. (Other Role), Cao, Q. (Other Role), Dasgupta, T. (Other Role), Hinderlie, P. (Other Role), Jin, D. D. (Other Role), Kennedy, P. (Other Role), Kile, Q. (Other Role), Kopp, B. (Other Role), Lenvik, T. R. (Other Role), Meyer, C. M. (Other Role), Phung, G. (Other Role), Ramesh, V. (Other Role), Sleeth, M. L. (Other Role), Soignier, Y. M. (Other Role) & Xia, L. H. (Other Role)
5/5/23 → 4/30/28
Project: Research project
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Immune Cell therapy for RDEB
Tolar, J. (PI) & Osborn, M. J. (CoI)
7/22/24 → 7/21/25
Project: Research project
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Autologous Revertant Mosaic Fibroblasts for Wound Healing in Dystrophic Epidermolysis Bullosa
Tolar, J. (PI), Ebens, C. (CoI) & Osborn, M. J. (CoI)
6/1/22 → 5/31/23
Project: Research project
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Analysis of readability of the top web searches for pediatric inborn errors of fatty acid metabolism
Sawyer, K., Miller, W., Popp, C., Strege, C., Eide, C. & Tolar, J., Mar 2025, In: Molecular Genetics and Metabolism Reports. 42, 101195.Research output: Contribution to journal › Article › peer-review
Open Access -
Deficiency of T follicular helper cell Tet3 DNA demethylation inhibits pathogenic IgG2c class switching and chronic GVHD
Zaiken, M. C., Jin, S., McDonald-Hyman, C. S., Hartigan, C. R., Sage, P. T., Hippen, K. L., Koehn, B. H., Panoskaltsis-Mortari, A., Riddle, M. J., Eide, C. R., Tolar, J., Hill, G. R., Luznik, L., Cutler, C. S., Ritz, J. R., Kean, L. S., Tsagaratou, A., Rao, A. & Blazar, B. R., Jun 12 2025, In: Blood. 145, 24, p. 2813-2827 15 p.Research output: Contribution to journal › Article › peer-review
4 Link opens in a new tab Scopus citations -
Efficient site-specific integration of large genes in mammalian cells via continuously evolved recombinases and prime editing
Pandey, S., Gao, X. D., Krasnow, N. A., McElroy, A., Tao, Y. A., Duby, J. E., Steinbeck, B. J., McCreary, J., Pierce, S. E., Tolar, J., Meissner, T. B., Chaikof, E. L., Osborn, M. J. & Liu, D. R., Jan 2025, In: Nature Biomedical Engineering. 9, 1, p. 22-39 18 p., 627.Research output: Contribution to journal › Article › peer-review
Open Access116 Link opens in a new tab Scopus citations -
Inflammasome-resistant IPSC-derived myeloid-derived suppressor cells ameliorate xenogeneic graft-versus-host disease
Ma, L., Koehn, B., Zaiken, M., Hippen, K. L., Smith, K., Allred, J., Williams, R., Yao, K., Fink, J., Saha, A., Koop, B., Payne, N., Widelak, R., Panoskaltsis-Mortari, A., Riddle, M. J., Tolar, J., Eide, C., Xia, L., Witty, A. D. & Mehta, A. K. & 9 others, , Oct 23 2025, In: Blood. 146, 17, p. 2047-2062 16 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Scopus citations -
New gene therapies for dystrophic epidermolysis bullosa: progress, promise and persistent gaps
McGrath, J. A. & Tolar, J., Nov 1 2025, In: British Journal of Dermatology. 193, 5, p. 809-810 2 p.Research output: Contribution to journal › Editorial › peer-review
Open Access
Datasets
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Supporting data for "3D Printed Functional and Biological Materials on Moving Freeform Surfaces"
Zhu, Z., Guo, S.-Z., Hirdler, T., Eide, C. R., Fan, X., Tolar, J. & McAlpine, M., Data Repository for the University of Minnesota, 2020
DOI: 10.13020/ch4p-mc89, http://hdl.handle.net/11299/213310
Dataset
Press/Media
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When ‘do no harm’ means doing more: University of Minnesota residents press medical school to take tougher action against racism.
9/11/20
1 item of Media coverage
Press/Media: Expert Comment or Interview
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Minnesota is not reaching daily COVID-19 testing capacity; those with symptoms urged to get tested
5/19/20
1 item of Media coverage
Press/Media: Expert Comment or Interview
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UMN medical dean says state’s lofty coronavirus testing goal ‘well on track’
5/8/20
1 item of Media coverage
Press/Media: Expert Comment or Interview
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Coronavirus In MN: Dr. Jakub Tolar Shows How Minnesota Is Using Science To Overcome Pandemic
5/6/20
1 item of Media coverage
Press/Media: Expert Comment or Interview
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Our View: COVID-19: Minnesota model holds promise in virus fight
4/26/20
1 Media contribution
Press/Media: Expert Comment or Interview