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Jakub Tolar

 https://orcid.org/0000-0002-0957-4380
1994 …2023
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Personal profile

Education/Academic qualification

PhD, University of Minnesota

Sep 1 1992 → Dec 31 1996

MD, Charles University

Sep 1 1984 → Sep 27 1990

Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

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Projects 1994 2023

Mayo Partnership in Regenerative Medicine

Tolar, J.

MINNESOTA REGENERATIVE MEDICINE

7/1/17 → 6/30/22

Project: Research project

Regenerative Medicine

Next Generation Genome Editing for RDEB

Tolar, J.

VARIOUS SPONSORS - NON-FEDERAL

1/4/17 → 1/3/19

Project: Research project

Gene Editing

Center for Modeling Tumor Cell Migration Mechanics

Odde, D. J., Alford, P. W., Barocas, V. H., Largaespada, D. A., Olin, M. R., Othmer, H. G., Provenzano, P., Schwertfeger, K., Tolar, J., Tranquillo, R. T. & Wood, D. K.

NIH NATIONAL CANCER INSTITUTE (NCI)

8/17/16 → 7/31/21

Project: Research project

Mechanics
Cell Movement
Neoplasms

Mayo Partnership in Regenerative Medicine

Tolar, J. & LeBien, T. W.

State of Minnesota

7/1/16 → 6/30/21

Project: Research project

Regenerative Medicine

NK Cells, Their Receptors, Transplantation and Cancer Th

Miller, J. S., Cooley, S. A., Ho, Y., Le, C. T., Luo, X., Tolar, J., Vallera, D. A., Verneris, M. R. & Weisdorf, D. J.

NIH NATIONAL CANCER INSTITUTE (NCI)

4/5/16 → 3/31/21

Project: Research project

Natural Killer Cell Receptors
Transplantation
Neoplasms
Therapeutics

Research Output 1996 2018

2 Citations

3D Printed Functional and Biological Materials on Moving Freeform Surfaces

Zhu, Z., Guo, S. Z., Hirdler, T., Eide, C., Fan, X., Tolar, J. & McAlpine, M. C., Jun 6 2018, In : Advanced Materials. 30, 23, 1707495

Research output: Contribution to journal › Article

Functional materials
Biological materials
Printing
Real time control
Ink

A multitask clustering approach for single-cell RNA-seq analysis in Recessive Dystrophic Epidermolysis Bullosa

Zhang, H., Lee, C. A. A., Li, Z., Garbe, J. R., Eide, C. R., Petegrosso, R., Kuang, R. & Tolar, J., Apr 1 2018, In : PLoS Computational Biology. 14, 4, e1006053

Research output: Contribution to journal › Article

epidermolysis bullosa
Epidermolysis Bullosa Dystrophica
RNA
Cluster Analysis
Clustering
1 Citations

ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism

Rousseaux, M. W. C. , Tschumperlin, T. , Lu, H. C. , Lackey, E. P. , Bondar, V. V. , Wan, Y. W. , Tan, Q. , Adamski, C. J. , Friedrich, J. , Twaroski, K. , Chen, W. , Tolar, J. , Henzler, C. , Sharma, A. , Bajić, A. , Lin, T. , Duvick, L. , Liu, Z. , Sillitoe, R. V. , Zoghbi, H. Y. & 1 others Orr, H. T., Mar 21 2018, In : Neuron. 97, 6, p. 1235-1243.e5

Research output: Contribution to journal › Article

Spinocerebellar Ataxias
Ataxia
Cerebellum
Pathology
Neurons

Crispr/cas9-based cellular engineering for targeted gene overexpression

Osborn, M. J., Lees, C. J., McElroy, A. N., Merkel, S. C., Eide, C. R., Mathews, W., Feser, C. J., Tschann, M., McElmury, R. T., Webber, B. R., Kim, C. J., Blazar, B. R. & Tolar, J., Apr 1 2018, In : International journal of molecular sciences. 19, 4, 946

Research output: Contribution to journal › Article

Cell Engineering
genes
Genes
engineering
T-cells
2 Citations

Human CD19-Targeted Mouse T Cells Induce B Cell Aplasia and Toxicity in Human CD19 Transgenic Mice

Pennell, C. A., Barnum, J. L., McDonald-Hyman, C. S., Panoskaltsis-Mortari, A., Riddle, M. J., Xiong, Z., Loschi, M., Thangavelu, G., Campbell, H. M., Storlie, M. D., Refaeli, Y., Furlan, S. N., Jensen, M. C., Kean, L. S., Miller, J. S., Tolar, J., Osborn, M. J. & Blazar, B. R., Jun 6 2018, In : Molecular Therapy. 26, 6, p. 1423-1434 12 p.

Research output: Contribution to journal › Article

Transgenic Mice
B-Lymphocytes
T-Lymphocytes
T-Cell Antigen Receptor
Cell- and Tissue-Based Therapy