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Research Output 1988 2019

2013
2 Citations (Scopus)

Applicability of 3T body MRI in assessment of nonfocal bone marrow involvement of hematopoietic neoplasia in dogs

Feeney, D. A., Sharkey, L. C., Steward, S. M., Bahr, K. L., Henson, M. S., Ito, D., O'Brien, T. D., Jessen, C. R., Husbands, B. D., Borgatti, A. & Modiano, J., Sep 1 2013, In : Journal of Veterinary Internal Medicine. 27, 5, p. 1165-1171 7 p.

Research output: Contribution to journalArticle

magnetic resonance imaging
bone marrow
Bone Marrow
Magnetic Resonance Imaging
Dogs
4 Citations (Scopus)

Arginase Treatment Prevents the Recovery of Canine Lymphoma and Osteosarcoma Cells Resistant to the Toxic Effects of Prolonged Arginine Deprivation

Wells, J. W., Evans, C. H., Scott, M. C., Rütgen, B. C., O'Brien, T. D., Modiano, J. F., Cvetkovic, G. & Tepic, S., Jan 30 2013, In : PloS one. 8, 1, e54464.

Research output: Contribution to journalArticle

Arginase
arginase
osteosarcoma
Poisons
Osteosarcoma
53 Citations (Scopus)

Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B

Karlsson, E. K., Sigurdsson, S., Ivansson, E., Thomas, R., Elvers, I., Wright, J., Howald, C., Tonomura, N., Perloski, M., Swofford, R., Biagi, T., Fryc, S., Anderson, N., Courtay-Cahen, C., Youell, L., Ricketts, S. L., Mandlebaum, S., Rivera, P., von Euler, H., Kisseberth, W. C. & 8 others, London, C. A., Lander, E. S., Couto, G., Comstock, K., Starkey, M. P., Modiano, J. F., Breen, M. & Lindblad-Toh, K., Dec 12 2013, In : Genome biology. 14, 12, R132.

Research output: Contribution to journalArticle

osteosarcoma
Osteosarcoma
genome
Genome
Dogs
18 Citations (Scopus)
Immunotoxins
Hemangiosarcoma
Neoplastic Stem Cells
Urokinase-Type Plasminogen Activator
Sarcoma
18 Citations (Scopus)

Isolation and characterization of canine natural killer cells

Michael, H. T., Ito, D., McCullar, V., Zhang, B., Miller, J. S. & Modiano, J. F., Sep 15 2013, In : Veterinary immunology and immunopathology. 155, 3, p. 211-217 7 p.

Research output: Contribution to journalArticle

natural killer cells
Natural Killer Cells
Canidae
Interleukin-15
dogs
61 Citations (Scopus)

MicroRNAs at the human 14q32 locus have prognostic significance in osteosarcoma.

Sarver, A. L., Thayanithy, V., Scott, M. C., Cleton-Jansen, A. M., Hogendoorn, P. C. W., Modiano, J. F. & Subramanian, S., Jan 1 2013, In : Unknown Journal. 8

Research output: Contribution to journalArticle

Open Access
Osteosarcoma
MicroRNAs
Canidae
Neoplasms
Down-Regulation
9 Citations (Scopus)

Molecular characterization of canine BCR-ABL-positive chronic myelomonocytic leukemia before and after chemotherapy

Culver, S., Ito, D., Borst, L., Bell, J. S., Modiano, J. F. & Breen, M., Sep 1 2013, In : Veterinary Clinical Pathology. 42, 3, p. 314-322 9 p.

Research output: Contribution to journalArticle

Leukemia, Myelomonocytic, Chronic
leukemia
drug therapy
Canidae
Cytogenetic Analysis
53 Citations (Scopus)

Molecular profiling reveals prognostically significant subtypes of canine lymphoma

Frantz, A. M., Sarver, A. L., Ito, D., Phang, T. L., Karimpour-Fard, A., Scott, M. C., Valli, V. E. O., Lindblad-Toh, K., Burgess, K. E., Husbands, B. D., Henson, M. S., Borgatti, A., Kisseberth, W. C., Hunter, L. E., Breen, M., O'Brien, T. D. & Modiano, J. F., Aug 1 2013, In : Veterinary pathology. 50, 4, p. 693-703 11 p.

Research output: Contribution to journalArticle

B-Cell Lymphoma
lymphoma
Canidae
Lymphoma
T-Cell Lymphoma
2 Citations (Scopus)

Parenchymal signal intensity in 3-T body MRI of dogs with hematopoietic neoplasia

Feeney, D. A., Sharkey, L. C., Steward, S. M., Bahr, K. L., Henson, M. S., Ito, D., O'Brien, T. D., Jessen, C. R., Husbands, B. D., Borgatti, A. & Modiano, J. F., Apr 1 2013, In : Comparative Medicine. 63, 2, p. 174-182 9 p.

Research output: Contribution to journalArticle

Liver
Magnetic resonance imaging
Muscle
Dogs
neoplasms
44 Citations (Scopus)

Targeting of Beta Adrenergic Receptors Results in Therapeutic Efficacy against Models of Hemangioendothelioma and Angiosarcoma

Stiles, J. M., Amaya, C., Rains, S., Diaz, D., Pham, R., Battiste, J., Modiano, J. F., Kokta, V., Boucheron, L. E., Mitchell, D. C. & Bryan, B. A., Mar 28 2013, In : PloS one. 8, 3, e60021.

Research output: Contribution to journalArticle

Hemangioendothelioma
Hemangiosarcoma
Receptors, Adrenergic, beta
Tumors
blood vessels
2012
41 Citations (Scopus)

A genome-wide approach to comparative oncology: High-resolution oligonucleotide aCGH of canine and human osteosarcoma pinpoints shared microaberrations

Angstadt, A. Y., Thayanithy, V., Subramanian, S., Modiano, J. F. & Breen, M., Nov 1 2012, In : Cancer genetics. 205, 11, p. 572-587 16 p.

Research output: Contribution to journalArticle

Osteosarcoma
Oligonucleotides
Canidae
Genome
Cytogenetics
8 Citations (Scopus)

Biomonitoring the cooked meat carcinogen 2-amino-1-methyl-6- phenylimidazo[4,5-b ]pyridine in canine fur

Gu, D., Neuman, Z. L., Modiano, J. F. & Turesky, R. J., Sep 12 2012, In : Journal of agricultural and food chemistry. 60, 36, p. 9371-9375 5 p.

Research output: Contribution to journalArticle

Meats
Environmental Monitoring
pyridines
carcinogens
Carcinogens
13 Citations (Scopus)

CD40 ligand is necessary and sufficient to support primary diffuse large B-cell lymphoma cells in culture: A tool for in vitro preclinical studies with primary B-cell malignancies

Ito, D., Frantz, A. M., Williams, C., Thomas, R., Burnett, R. C., Avery, A. C., Breen, M., Mason, N. J., O'Brien, T. D. & Modiano, J. F., Jul 1 2012, In : Leukemia and Lymphoma. 53, 7, p. 1390-1398 9 p.

Research output: Contribution to journalArticle

CD40 Ligand
Lymphoma, Large B-Cell, Diffuse
B-Lymphocytes
Cell Culture Techniques
Feeder Cells
39 Citations (Scopus)

Combinatorial Treatment of DNA and Chromatin-Modifying Drugs Cause Cell Death in Human and Canine Osteosarcoma Cell Lines

Thayanithy, V., Park, C., Sarver, A. L., Kartha, R. V., Korpela, D. M., Graef, A. J., Steer, C. J., Modiano, J. F. & Subramanian, S., Sep 5 2012, In : PLoS One. 7, 9, e43720.

Research output: Contribution to journalArticle

osteosarcoma
Cell death
Osteosarcoma
MicroRNAs
microRNA
21 Citations (Scopus)

Inflammation, apoptosis, and necrosis induced by neoadjuvant fas ligand gene therapy improves survival of dogs with spontaneous bone cancer

Modiano, J. F., Bellgrau, D., Cutter, G. R., Lana, S. E., Ehrhart, N. P., Ehrhart, E., Wilke, V. L., Charles, J. B., Munson, S., Scott, M. C., Pozniak, J., Carlson, C. S., Schaack, J. & Duke, R. C., Jan 1 2012, In : Molecular Therapy. 20, 12, p. 2234-2243 10 p.

Research output: Contribution to journalArticle

Bone Neoplasms
Fas Ligand Protein
Genetic Therapy
Necrosis
Dogs
90 Citations (Scopus)

Perturbation of 14q32 miRNAs-cMYC gene network in osteosarcoma

Thayanithy, V., Sarver, A. L., Kartha, R. V., Li, L., Angstadt, A. Y., Breen, M., Steer, C. J., Modiano, J. F. & Subramanian, S., Jan 1 2012, In : Bone. 50, 1, p. 171-181 11 p.

Research output: Contribution to journalArticle

Gene Regulatory Networks
Osteosarcoma
MicroRNAs
Down-Regulation
DNA Copy Number Variations
212 Citations (Scopus)

Rethinking dog domestication by integrating genetics, archeology, and biogeography

Larson, G., Karlsson, E. K., Perri, A., Webster, M. T., Ho, S. Y. W., Peters, J., Stahl, P. W., Piper, P. J., Lingaas, F., Fredholm, M., Comstock, K. E., Modiano, J. F., Schelling, C., Agoulnik, A. I., Leegwater, P. A., Dobney, K., Vigne, J. D., Vilà, C., Andersson, L. & Lindblad-Toh, K., Jun 5 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 23, p. 8878-8883 6 p.

Research output: Contribution to journalArticle

Archaeology
Dogs
New Guinea
Domestication
Singing
2011
18 Citations (Scopus)

A tumor-related lymphoid progenitor population supports hierarchical tumor organization in canine B-cell lymphoma

Ito, D., EndicottM.M., N. V., Jubala, C. M., Helm, K. M., Burnett, R. C., Husbands, B. D., Borgatti, A., Henson, M. S., Burgess, K. E., Bell, J. S., Kisseberth, W. C., Valli, V. E., Cutter, G. R., Avery, A. C., Hahn, K. A., O'Brien, T. D. & Modiano, J. F., Jul 1 2011, In : Journal of veterinary internal medicine. 25, 4, p. 890-896 7 p.

Research output: Contribution to journalArticle

B-Cell Lymphoma
lymphoma
B-lymphocytes
Canidae
Lymphoid Progenitor Cells
43 Citations (Scopus)

Characterization of canine osteosarcoma by array comparative genomic hybridization and RT-qPCR: Signatures of genomic imbalance in canine osteosarcoma parallel the human counterpart

Angstadt, A. Y., Motsinger-Reif, A., Thomas, R., Kisseberth, W. C., Guillermo Couto, C., Duval, D. L., Nielsen, D. M., Modiano, J. F. & Breen, M., Nov 1 2011, In : Genes Chromosomes and Cancer. 50, 11, p. 859-874 16 p.

Research output: Contribution to journalArticle

Comparative Genomic Hybridization
Osteosarcoma
Canidae
Dogs
Neoplasms
20 Citations (Scopus)
Nicotine
Carcinogenesis
Lung
Neoplasms
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
5 Citations (Scopus)

Immunotherapy with autologous tumour antigen-coated microbeads (large multivalent immunogen), IL-2 and GM-CSF in dogs with spontaneous B-cell lymphoma

Henson, M. S., Curtsinger, J. M., Larson, V. S., Klausner, J. S., Modiano, J. F., Mescher, M. F. & Miller, J. S., Jun 1 2011, In : Veterinary and Comparative Oncology. 9, 2, p. 95-105 11 p.

Research output: Contribution to journalArticle

granulocyte-macrophage colony-stimulating factor
immunotherapy
Autoantigens
B-Cell Lymphoma
Neoplasm Antigens
67 Citations (Scopus)

Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach

Scott, M. C., Sarver, A. L., Gavin, K. J., Thayanithy, V., Getzy, D. M., Newman, R. A., Cutter, G. R., Lindblad-Toh, K., Kisseberth, W. C., Hunter, L. E., Subramanian, S., Breen, M. & Modiano, J. F., Sep 1 2011, In : Bone. 49, 3, p. 356-367 12 p.

Research output: Contribution to journalArticle

Osteosarcoma
Dogs
Neoplasms
Gene Expression
Gene Expression Profiling
51 Citations (Scopus)

Refining tumor-associated aneuploidy through 'genomic recoding' of recurrent DNA copy number aberrations in 150 canine non-Hodgkin lymphomas

Thomas, R., Seiser, E. L., Motsinger-Reif, A., Borst, L., Valli, V. E., Kelley, K., Suter, S. E., Argyle, D., Burgess, K., Bell, J., Lindblad-Toh, K., Modiano, J. F. & Breen, M., Jul 1 2011, In : Leukemia and Lymphoma. 52, 7, p. 1321-1335 15 p.

Research output: Contribution to journalArticle

Aneuploidy
Non-Hodgkin's Lymphoma
Canidae
DNA
Neoplasms
54 Citations (Scopus)

Gene expression profiling identifies inflammation and angiogenesis as distinguishing features of canine hemangiosarcoma

Tamburini, B. A., Phang, T. L., Fosmire, S. P., Scott, M. C., Trapp, S. C., Duckett, M. M., Robinson, S. R., Slansky, J. E., Sharkey, L. C., Cutter, G. R., Wojcieszyn, J. W., Bellgrau, D., Gemmill, R. M., Hunter, L. E. & Modiano, J. F., Nov 9 2010, In : BMC Cancer. 10, 619.

Research output: Contribution to journalArticle

Hemangiosarcoma
Gene Expression Profiling
Canidae
Inflammation
Neoplasms
1 Citation (Scopus)
Cats
radiotherapy
irradiation
cats
Safety
13 Citations (Scopus)

Nicotine-mediated signals modulate cell death and survival of T lymphocytes

Oloris, S. C. S., Frazer-Abel, A. A., Jubala, C. M., Fosmire, S. P., Helm, K. M., Robinson, S. R., Korpela, D. M., Duckett, M. M., Baksh, S. & Modiano, J. F., Feb 1 2010, In : Toxicology and Applied Pharmacology. 242, 3, p. 299-309 11 p.

Research output: Contribution to journalArticle

T-cells
Lymphocytes
Cell death
Nicotine
Cell Survival
6 Citations (Scopus)

Pharmacological inhibition of cyclin dependent kinases causes p53 dependent apoptosis in renal cell carcinoma

Ishimaru, T., Lau, J., Jackson, A. L., Modiano, J. F. & Weiss, R. H., Nov 1 2010, In : Journal of Urology. 184, 5, p. 2143-2149 7 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinases
Renal Cell Carcinoma
Pharmacology
Apoptosis
Cell Line
2009
102 Citations (Scopus)

Artemisinin blocks prostate cancer growth and cell cycle progression by disrupting Sp1 interactions with the cyclin-dependent kinase-4 (CDK4) promoter and inhibiting CDK4 gene expression

Willoughby, J. A., Sundar, S. N., Cheung, M., Tin, A. S., Modiano, J. & Firestone, G. L., Jan 23 2009, In : Journal of Biological Chemistry. 284, 4, p. 2203-2213 11 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinase 4
Gene expression
Prostatic Neoplasms
Cell Cycle
Cells
47 Citations (Scopus)

Gene expression profiles of sporadic canine hemangiosarcoma are uniquely associated with breed

Tamburini, B. A., Trapp, S., Phang, T. L., Schappa, J. T., Hunter, L. E. & Modiano, J. F., May 20 2009, In : PloS one. 4, 5, e5549.

Research output: Contribution to journalArticle

hemangiosarcoma
Hemangiosarcoma
Transcriptome
Gene expression
Canidae

Genetic basis of cancer

Modiano, J. F. & Breen, M., Dec 1 2009, Cancer Management in Small Animal Practice. Saunders Elsevier, p. 10-15 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

neoplasms
Neoplasms
53 Citations (Scopus)

Influence of genetic background on tumor karyotypes: Evidence for breed-associated cytogenetic aberrations in canine appendicular osteosarcoma

Thomas, R., Wang, H. J., Tsai, P. C., Langford, C. F., Fosmire, S. P., Jubala, C. M., Getzy, D. M., Cutter, G. R., Modiano, J. F. & Breen, M., Apr 1 2009, In : Chromosome Research. 17, 3, p. 365-377 13 p.

Research output: Contribution to journalArticle

Osteosarcoma
Karyotype
Chromosome Aberrations
Canidae
Neoplasms
7 Citations (Scopus)

MHC-dependent desensitization of intrinsic anti-self reactivity

Jubala, C. M., Lamerato-Kozicki, A. R., Borakove, M., Lang, J., Gardner, L. A., Coffey, D., Helm, K. M., Schaack, J., Baier, M., Cutter, G. R., Bellgrau, D. & Modiano, J. F., Feb 1 2009, In : Cancer Immunology, Immunotherapy. 58, 2, p. 171-185 15 p.

Research output: Contribution to journalArticle

Major Histocompatibility Complex
T-Lymphocytes
Antigens
Neoplasms
Inbred NOD Mouse
2008
149 Citations (Scopus)
Hematologic Neoplasms
Cytogenetics
Dogs
Chromosome Aberrations
Neoplasms
21 Citations (Scopus)

Negative regulators in homeostasis of naïve peripheral T cells

Modiano, J. F., Johnson, L. D. S. & Bellgrau, D., Jun 1 2008, In : Immunologic Research. 41, 2, p. 137-153 17 p.

Research output: Contribution to journalReview article

Homeostasis
T-Lymphocytes
Peripheral Tolerance
Population Dynamics
Cell Cycle
2007
32 Citations (Scopus)

Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: A potential mechanism of apoptosis resistance

Lin, P. Y., Fosmire, S. P., Park, S. H., Park, J. Y., Baksh, S., Modiano, J. F. & Weiss, R. H., Mar 9 2007, In : Molecular Cancer. 6, 16.

Research output: Contribution to journalArticle

Kidney Neoplasms
Apoptosis
1-Phosphatidylinositol 4-Kinase
Renal Cell Carcinoma
Cell Line
34 Citations (Scopus)

Inactivation of the p16 cyclin-dependent kinase inhibitor in high-grade canine non-Hodgkin's T-cell lymphoma

Fosmire, S. P., Thomas, R., Jubala, C. M., Wojcieszyn, J. W., Valli, V. E. O., Getzy, D. M., Smith, T. L., Gardner, L. A., Ritt, M. G., Bell, J. S., Freeman, K. P., Greenfield, B. E., Lana, S. E., Kisseberth, W. C., Helfand, S. C., Cutter, G. R., Breen, M. & Modiano, J., Jul 1 2007, In : Veterinary pathology. 44, 4, p. 467-478 12 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinase Inhibitor p16
non-Hodgkin lymphoma
cyclin-dependent kinase
T-Cell Lymphoma
lymphoma
25 Citations (Scopus)

Predictive value of p16 or Rb inactivation in a model of naturally occurring canine non-Hodgkin's lymphoma [7]

Modiano, J. F., Breen, M., Valli, V. E. O., Wojcieszyn, J. W. & Cutter, G. R., Jan 1 2007, In : Leukemia. 21, 1, p. 184-187 4 p.

Research output: Contribution to journalLetter

Predictive Value of Tests
Dog Diseases
Retinoblastoma Genes
p16 Genes
Animal Disease Models
2006
69 Citations (Scopus)

Canine hemangiosarcoma originates from hematopoietic precursors with potential for endothelial differentiation

Lamerato-Kozicki, A. R., Helm, K. M., Jubala, C. M., Cutter, G. C. & Modiano, J., Jul 1 2006, In : Experimental Hematology. 34, 7, p. 870-878 9 p.

Research output: Contribution to journalArticle

Hemangiosarcoma
Canidae
Dogs
Flow Cytometry
Hemangioblasts
15 Citations (Scopus)

Naturally occurring translational models for development of cancer gene therapy

Modiano, J. F., Breen, M., Lana, S. E., Ehrhart, N., Fosmire, S. P., Thomas, R., Jubala, C. M., Lamerato-Kozicki, A. R., Ehrhart, E. J., Schaack, J., Duke, R. C., Cutter, G. C. & Bellgrau, D., Jun 1 2006, In : Gene Therapy and Molecular Biology. 10, 1, p. 31-40 10 p.

Research output: Contribution to journalReview article

Neoplasm Genes
Genetic Therapy
Neoplasms
Fas Ligand Protein
Dogs
206 Citations (Scopus)

The dog as a cancer model [2]

Khanna, C., Lindblad-Toh, K., Vail, D., London, C., Bergman, P., Barber, L., Breen, M., Kitchell, B., McNeil, E., Modiano, J. F., Niemi, S., Comstock, K. E., Ostrander, E., Westmoreland, S. & Withrow, S., Sep 1 2006, In : Nature Biotechnology. 24, 9, p. 1065-1066 2 p.

Research output: Contribution to journalLetter

Animal Disease Models
Animals
Dogs
Neoplasms
2005
52 Citations (Scopus)

CD20 expression in normal canine B cells and in canine non-Hodgkin lymphoma

Jubala, C. M., Wojcieszyn, J. W., Valli, V. E. O., Getzy, D. M., Fosmire, S. P., Coffey, D., Bellgrau, D. & Modiano, J. F., Jul 1 2005, In : Veterinary Pathology. 42, 4, p. 468-476 9 p.

Research output: Contribution to journalArticle

non-Hodgkin lymphoma
Non-Hodgkin's Lymphoma
B-lymphocytes
Canidae
B-Lymphocytes
41 Citations (Scopus)

Construction of a 2-Mb resolution BAC microarray for CGH analysis of canine tumors

Thomas, R., Scott, A., Langford, C. F., Fosmire, S. P., Jubala, C. M., Lorentzen, T. D., Hitte, C., Karlsson, E. K., Kirkness, E., Ostrander, E. A., Galibert, F., Lindblad-Toh, K., Modiano, J. F. & Breen, M., Dec 1 2005, In : Genome Research. 15, 12, p. 1831-1837 7 p.

Research output: Contribution to journalArticle

Comparative Genomic Hybridization
Canidae
Neoplasms
Cytogenetics
Clone Cells
115 Citations (Scopus)

Distinct B-cell and T-cell lymphoproliferative disease prevalence among dog breeds indicates heritable risk

Modiano, J. F., Breen, M., Burnett, R. C., Parker, H. G., Inusah, S., Thomas, R., Avery, P. R., Lindblad-Toh, K., Ostrander, E. A., Cutter, G. C. & Avery, A. C., Jul 1 2005, In : Cancer Research. 65, 13, p. 5654-5661 8 p.

Research output: Contribution to journalArticle

B-Lymphocytes
Dogs
T-Lymphocytes
Population
Immunoglobulin Heavy Chains
45 Citations (Scopus)

Mutations of phosphatase and tensin homolog deleted from chromosome 10 in canine hemangiosarcoma

Dickerson, E. B., Thomas, R., Fosmire, S. P., Lamerato-Kozicki, A. R., Bianco, S. R., Wojcieszyn, J. W., Breen, M., Helfand, S. C. & Modiano, J. F., Sep 1 2005, In : Veterinary pathology. 42, 5, p. 618-632 15 p.

Research output: Contribution to journalArticle

hemangiosarcoma
Chromosomes, Human, Pair 10
Hemangiosarcoma
Phosphoric Monoester Hydrolases
Canidae
2004
74 Citations (Scopus)

Canine malignant hemangiosarcoma as a model of primitive angiogenic endothelium

Fosmire, S. P., Dickerson, E. B., Scott, A. M., Bianco, S. R., Pettengill, M. J., Meylemans, H., Padilla, M., Frazer-Abel, A. A., Akhtar, N., Getzy, D. M., Wojcieszyn, J., Breen, M., Helfand, S. C. & Modiano, J. F., May 1 2004, In : Laboratory Investigation. 84, 5, p. 562-572 11 p.

Research output: Contribution to journalArticle

Hemangiosarcoma
Endothelium
Canidae
Cell Line
Endothelial Growth Factors
11 Citations (Scopus)

Fas ligand-dependent suppression of autoimmunity via recruitment and subsequent termination of activated T cells

Modiano, J. F., Sun, J., Lang, J., Vacano, G., Patterson, D., Chan, D., Franzusoff, A., Gianani, R., Meech, S. J., Duke, R. & Bellgrau, D., Jul 1 2004, In : Clinical Immunology. 112, 1, p. 54-65 12 p.

Research output: Contribution to journalArticle

Fas Ligand Protein
Autoimmunity
T-Lymphocytes
Experimental Arthritis
CD95 Antigens
22 Citations (Scopus)

Nicotine activates nuclear factor of activated T cells c2 (NFATc2) and prevents cell cycle entry in T cells

Frazer-Abel, A. A., Baksh, S., Fosmire, S. P., Willis, D., Pierce, A. M., Meylemans, H., Linthicum, D. S., Burakoff, S. J., Coons, T., Bellgrau, D. & Modiano, J. F., Nov 1 2004, In : Journal of Pharmacology and Experimental Therapeutics. 311, 2, p. 758-769 12 p.

Research output: Contribution to journalArticle

NFATC Transcription Factors
Nicotine
Cell Cycle
T-Lymphocytes
Cyclin-Dependent Kinase 4
2003
231 Citations (Scopus)

Diagnosis of canine lymphoid neoplasia using clonal rearrangements of antigen receptor genes

Burnett, R. C., Vernau, W., Modiano, J., Olver, C. S., Moore, P. F. & Avery, A. C., Jan 1 2003, In : Veterinary pathology. 40, 1, p. 32-41 10 p.

Research output: Contribution to journalArticle

Antigen Receptors
leukemia
Canidae
Lymphoma
lymphoma
3 Citations (Scopus)

Early changes in metabolism of leukemic cell lines upon induction of apoptosis by cytotoxic drugs

Khare, S., Banai, Y., Gokulan, K., Smith, R., Linthicum, D. S. & Modiano, J. F., Mar 28 2003, In : European Journal of Pharmacology. 465, 1-2, p. 23-30 8 p.

Research output: Contribution to journalArticle

Camptothecin
Paclitaxel
Apoptosis
Cell Line
U937 Cells