Iryna Khasabova

1988 …2024
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Hyperalgesia Medicine & Life Sciences
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Cannabinoid Receptor CB2 Medicine & Life Sciences
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Projects 2009 2024

Cancer Pain
Cannabinoids
Hyperalgesia
Sensory Receptor Cells
Neoplasms

Dysregulation of Endocannabinoid Metabolism Contributes

Seybold, V. S. & Khasabova, I.

MN MED FDN

3/1/092/28/11

Project: Research project

Research Output 1988 2019

Pioglitazone, a PPARγ agonist, reduces cisplatin-evoked neuropathic pain by protecting against oxidative stress

Khasabova, I., Khasabov, S., Olson, J., Uhelski, M. L., Kim, A. H., Albino-Ramírez, A. M., Wagner, C. L., Seybold, V. S. & Simone, D. A., Mar 1 2019, In : Pain. 160, 3, p. 688-701 14 p.

Research output: Contribution to journalArticle

pioglitazone
Peroxisome Proliferator-Activated Receptors
Neuralgia
Cisplatin
Oxidative Stress
2 Citations (Scopus)
Prostaglandins G
Nociceptors
Hyperalgesia
Sickle Cell Anemia
Prostaglandins E
12 Citations (Scopus)
Endocannabinoids
Nociceptors
Peripheral Nervous System Diseases
Hydrolysis
Drug Therapy
5 Citations (Scopus)

Molecular mechanism for opioid dichotomy: bidirectional effect of μ-opioid receptors on P2X3 receptor currents in rat sensory neurones

Chizhmakov, I., Kulyk, V., Khasabova, I., Khasabov, S., Simone, D. A., Bakalkin, G., Gordienko, D., Verkhratsky, A. & Krishtal, O., Jun 1 2015, In : Purinergic Signalling. 11, 2, p. 171-181 11 p.

Research output: Contribution to journalArticle

Purinergic P2X3 Receptors
Opioid Receptors
Sensory Receptor Cells
Opioid Analgesics
Pertussis Toxin
11 Citations (Scopus)

JZL184 is anti-hyperalgesic in a murine model of cisplatin-induced peripheral neuropathy

Khasabova, I., Yao, X., Paz, J., Lewandowski, C. T., Lindberg, A. E., Coicou, L., Burlakova, N., Simone, D. A. & Seybold, V. S., Jan 1 2014, In : Pharmacological Research. 90, p. 67-75 9 p.

Research output: Contribution to journalArticle

Peripheral Nervous System Diseases
Cisplatin
Hyperalgesia
Spinal Ganglia
Cannabinoid Receptor CB2