Hubert H Lim

20002022

Research output per year

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Research Output

2019

Frequency-specific activation of the peripheral auditory system using optoacoustic laser stimulation

Stahn, P., Lim, H. H., Hinsberger, M. P., Sorg, K., Pillong, L., Kannengießer, M., Schreiter, C., Foth, H. J., Langenbucher, A., Schick, B. & Wenzel, G. I., Dec 1 2019, In : Scientific reports. 9, 1, 4171.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Noninvasive ultrasound stimulation of the spleen to treat inflammatory arthritis

Zachs, D. P., Offutt, S. J., Graham, R. S., Kim, Y., Mueller, J., Auger, J. L., Schuldt, N. J., Kaisers, C. R. W., Heiiler, A. P., Dutta, R., Guo, H., Alford, J. K., Binstadt, B. A. & Lim, H. H., Mar 12 2019, In : Nature communications. 10

Research output: Contribution to journalArticle

4 Scopus citations

Peripheral Focused Ultrasound Stimulation (pFUS): New Competitor in Pharmaceutical Markets?

Cotero, V., Graf, J., Zachs, D. P., Tracey, K. J., Ashe, J., Lim, H. H. & Puleo, C., Aug 1 2019, In : SLAS Technology. 24, 4, p. 448-452 5 p.

Research output: Contribution to journalArticle

Open Access
2018

A bidirectional neuromodulation technology for nerve recording and stimulation

Xu, J., Guo, H., Nguyen, A. T., Lim, H. & Yang, Z., Oct 23 2018, In : Micromachines. 9, 11, 538.

Research output: Contribution to journalReview article

4 Scopus citations

A Low-Noise, Wireless, Frequency-Shaping Neural Recorder

Xu, J., Nguyen, A. T., Zhao, W., Guo, H., Wu, T., Wiggins, H., Keefer, E. W., Lim, H. & Yang, Z., Jun 2018, In : IEEE Journal on Emerging and Selected Topics in Circuits and Systems. 8, 2, p. 187-200 14 p.

Research output: Contribution to journalArticle

2 Scopus citations

Erratum: Ultrasound Produces Extensive Brain Activation via a Cochlear Pathway (Neuron (2018) 98(5) (1020–1030.e4), (S0896627318303714) (10.1016/j.neuron.2018.04.036))

Guo, H., Hamilton, M., Offutt, S. J., Gloeckner, C. D., Li, T., Kim, Y., Legon, W., Alford, J. K. & Lim, H. H., Aug 22 2018, In : Neuron. 99, 4, 1 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

Ultrasound Produces Extensive Brain Activation via a Cochlear Pathway

Guo, H., Hamilton, M., Offutt, S. J., Gloeckner, C. D., Li, T., Kim, Y., Legon, W., Alford, J. K. & Lim, H. H., Jun 6 2018, In : Neuron. 98, 5, p. 1020-1030.e4

Research output: Contribution to journalArticle

34 Scopus citations
2017

A Streaming PCA VLSI Chip for Neural Data Compression

Wu, T., Zhao, W., Guo, H., Lim, H. H. & Yang, Z., Dec 2017, In : IEEE transactions on biomedical circuits and systems. 11, 6, p. 1290-1302 13 p., 8010351.

Research output: Contribution to journalArticle

5 Scopus citations

Restoring hearing with neural prostheses: Current status and future directions

Lim, H. H., Adams, M. E., Nelson, P. B. & Oxenham, A. J., Mar 10 2017, Neuroprosthetics: Theory and Practice: Second Edition. World Scientific Publishing Co. Pte Ltd, p. 668-709 42 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
2016

A streaming PCA based VLSI chip for neural data compression

Wu, T., Zhao, W., Guo, H., Lim, H. & Yang, Z., Jan 1 2016, Proceedings - 2016 IEEE Biomedical Circuits and Systems Conference, BioCAS 2016. Institute of Electrical and Electronics Engineers Inc., p. 192-195 4 p. 7833764. (Proceedings - 2016 IEEE Biomedical Circuits and Systems Conference, BioCAS 2016).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations
2015

Auditory midbrain implant: Research and development towards a second clinical trial

Lim, H. H. & Lenarz, T., Apr 1 2015, In : Hearing Research. 322, p. 212-223 12 p.

Research output: Contribution to journalReview article

17 Scopus citations

Descending and tonotopic projection patterns from the auditory cortex to the inferior colliculus

Straka, M. M., Hughes, R., Lee, P. & Lim, H. H., Aug 6 2015, In : Neuroscience. 300, p. 325-337 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Improving neural decoding in the central auditory system using bio-inspired spectro-temporal representations and a generalized bilinear model

Siahpoush, S., Erfani, Y., Rode, T., Lim, H. H., Rouat, J. & Plourde, E., Nov 4 2015, 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Institute of Electrical and Electronics Engineers Inc., p. 5146-5150 5 p. 7319550. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; vol. 2015-November).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Investigating a new neuromodulation treatment for brain disorders using synchronized activation of multimodal pathways

Markovitz, C. D., Smith, B. T., Gloeckner, C. D. & Lim, H. H., 2015, In : Scientific reports. 5, 9462.

Research output: Contribution to journalArticle

5 Scopus citations

Measuring the signal-to-noise ratio of a neuron

Czanner, G., Sarma, S. V., Ba, D., Eden, U. T., Wu, W., Eskandar, E., Lim, H. H., Temereanca, S., Suzuki, W. A. & Brown, E. N., Jun 9 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 23, p. 7141-7146 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Pairing broadband noise with cortical stimulation induces extensive suppression of ascending sensory activity

Markovitz, C. D., Hogan, P. S., Wesen, K. A. & Lim, H. H., Apr 1 2015, In : Journal of neural engineering. 12, 2, 026006.

Research output: Contribution to journalArticle

3 Scopus citations

Positron emission tomography imaging reveals auditory and frontal cortical regions involved with speech perception and loudness adaptation

Berding, G., Wilke, F., Rode, T., Haense, C., Joseph, G., Meyer, G. J., Mamach, M., Lenarz, M., Geworski, L., Bengel, F. M., Lenarz, T. & Lim, H. H., Jun 5 2015, In : PloS one. 10, 6, e0128743.

Research output: Contribution to journalArticle

13 Scopus citations

The contribution of trained parameters to the goodness of fit of a Bayesian neural encoding model for the auditory system

Plourde, E., Rode, T. & Lim, H. H., Jan 1 2015, 2015 7th International IEEE/EMBS Conference on Neural Engineering, NER 2015. IEEE Computer Society, Vol. 2015-July. p. 910-913 4 p. 7146773

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Two laskers and counting: Learning from the past enables future innovations with central neural prostheses

Lim, H. H. & Shannon, R. V., Jan 1 2015, In : Brain Stimulation. 8, 3, p. 439-441 3 p.

Research output: Contribution to journalEditorial

3 Scopus citations
2014

Effects of location and timing of co-activated neurons in the auditory midbrain on cortical activity: Implications for a new central auditory prosthesis

Straka, M. M., McMahon, M., Markovitz, C. D. & Lim, H. H., Aug 1 2014, In : Journal of neural engineering. 11, 4, 046021.

Research output: Contribution to journalArticle

7 Scopus citations

Response features across the auditory midbrain reveal an organization consistent with a dual lemniscal pathway

Straka, M. M., Schmitz, S. & Lim, H. H., Aug 15 2014, In : Journal of neurophysiology. 112, 4, p. 981-988 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
10 Scopus citations
2013

A new concept for noninvasive tinnitus treatment utilizing multimodal pathways

Gloeckner, C. D., Smith, B. T., Markovitz, C. D. & Lim, H. H., Oct 31 2013, 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013. p. 3122-3125 4 p. 6610202. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Frequency representation within the human brain: Stability versus plasticity

Lim, H. H., Lenarz, M., Joseph, G. & Lenarz, T., Apr 10 2013, In : Scientific reports. 3, 1474.

Research output: Contribution to journalArticle

14 Scopus citations

Investigation of a new electrode array technology for a central auditory prosthesis

Calixto, R., Salamat, B., Rode, T., Hartmann, T., Volckaerts, B., Ruther, P., Lenarz, T. & Lim, H. H., Dec 2 2013, In : PloS one. 8, 12, e82148.

Research output: Contribution to journalArticle

8 Scopus citations

Neural integration and enhancement from the inferior colliculus up to different layers of auditory cortex

Straka, M. M., Schendel, D. & Lim, H. H., May 8 2013, In : Journal of neurophysiology. 110, 4, p. 1009-1020 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Neural representation in the auditory midbrain of the envelope of vocalizations based on a peripheral ear model

Rode, T., Hartmann, T., Hubka, P., Scheper, V., Lenarz, M., Lenarz, T., Kral, A. & Lim, H. H., Oct 21 2013, In : Frontiers in Neural Circuits. 7, OCT, 166.

Research output: Contribution to journalArticle

11 Scopus citations

Neuromodulation for brain disorders: Challenges and opportunities

Johnson, M. D., Lim, H. H., Netoff, T. I., Connolly, A. T., Johnson, N., Roy, A., Holt, A., Lim, K. O., Carey, J. R., Vitek, J. L. & He, B., Oct 1 2013, In : IEEE Transactions on Biomedical Engineering. 60, 3, p. 610-624 15 p.

Research output: Contribution to journalReview article

69 Scopus citations

Temporal processing in the auditory system: Insights from cochlear and auditory midbrain implantees

McKay, C. M., Lim, H. H. & Lenarz, T., Feb 1 2013, In : JARO - Journal of the Association for Research in Otolaryngology. 14, 1, p. 103-124 22 p.

Research output: Contribution to journalArticle

27 Scopus citations

Tonotopic and localized pathways from primary auditory cortex to the central nucleus of the inferior colliculus

Markovitz, C. D., Tang, T. T. & Lim, H. H., Apr 4 2013, In : Frontiers in Neural Circuits. APR 2013

Research output: Contribution to journalArticle

18 Scopus citations
2012

Coactivation of different neurons within an isofrequency lamina of the inferior colliculus elicits enhanced auditory cortical activation

Calixto, R., Lenarz, M., Neuheiser, A., Scheper, V., Lenarz, T. & Lim, H. H., Aug 15 2012, In : Journal of neurophysiology. 108, 4, p. 1199-1210 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Three-dimensional brain reconstruction of in vivo electrode tracks for neuroscience and neural prosthetic applications

Markovitz, C. D., Tang, T. T., Edge, D. P. & Lim, H. H., Jun 27 2012, In : Frontiers in Neural Circuits. JUNE 2012

Research output: Contribution to journalArticle

14 Scopus citations
2010

Effects of pulse phase duration and location of stimulation within the inferior colliculus on auditory cortical evoked potentials in a guinea pig model

Neuheiser, A., Lenarz, M., Reuter, G., Calixto, R., Nolte, I., Lenarz, T. & Lim, H. H., Dec 1 2010, In : JARO - Journal of the Association for Research in Otolaryngology. 11, 4, p. 689-708 20 p.

Research output: Contribution to journalArticle

12 Scopus citations

Hearing restoration with a central auditory prosthesis in neurofibromatosis type II

Lenarz, M., Lim, H. & Lenarz, T., Dec 1 2010, In : Otorinolaringologia. 60, 4, p. 245-252 8 p.

Research output: Contribution to journalReview article

2009

Auditory Midbrain Implant: A Review

Lim, H. H., Lenarz, M. & Lenarz, T., Sep 2009, In : Trends in Amplification. 13, 3, p. 149-180 32 p.

Research output: Contribution to journalArticle

54 Scopus citations

Green laser light activates the inner ear

Wenzel, G. I., Balster, S., Zhang, K., Lim, H. H., Reich, U., Massow, O., Lubatschowski, H., Ertmer, W., Lenarz, T. & Reuter, G., Dec 1 2009, In : Journal of biomedical optics. 14, 4, 044007.

Research output: Contribution to journalArticle

36 Scopus citations

Optoacoustic induced vibrations within the inner ear

Zhang, K. Y., Wenzel, G. I., Balster, S., Lim, H. H., Lubatschowski, H., Lenarz, T., Ertmer, W. & Reuter, G., Dec 7 2009, In : Optics Express. 17, 25, p. 23037-23043 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

Stimulation of the cochlea using green laser light

Wenzel, G. I., Balster, S., Lim, H. H., Zhang, K., Reich, U., Lubatschowski, H., Ertmer, W., Lenarz, T. & Reuter, G., Jun 8 2009, In : Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 7161, 71611Z.

Research output: Contribution to journalConference article

2 Scopus citations

Zentral-auditorische Implantate

Translated title of the contribution: Central auditory prosthesisLenarz, T., Lim, H., Joseph, G., Reuter, G. & Lenarz, M., Jun 1 2009, In : HNO. 57, 6, p. 551-562 12 p.

Research output: Contribution to journalArticle

2 Scopus citations
2008

Effects of phase duration and pulse rate on loudness and pitch percepts in the first auditory midbrain implant patients: Comparison to cochlear implant and auditory brainstem implant results

Lim, H. H., Lenarz, T., Joseph, G., Battmer, R. D., Patrick, J. F. & Lenarz, M., Jun 12 2008, In : Neuroscience. 154, 1, p. 370-380 11 p.

Research output: Contribution to journalArticle

31 Scopus citations

The auditory midbrain implant: Effects of electrode location

Lim, H. H., Lenarz, T., Anderson, D. J. & Lenarz, M., Aug 1 2008, In : Hearing Research. 242, 1-2, p. 74-85 12 p.

Research output: Contribution to journalArticle

43 Scopus citations
2007
38 Scopus citations

Auditory midbrain implant: Histomorphologic effects of long-term implantation and electric stimulation of a new deep brain stimulation array

Lenarz, M., Lim, H. H., Lenarz, T., Reich, U., Marquardt, N., Klingberg, M. N., Paasche, G., Reuter, G. & Stan, A. C., Dec 1 2007, In : Otology and Neurotology. 28, 8, p. 1045-1052 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

Auditory midbrain implant: A combined approach for vestibular schwannoma surgery and device implantation

Samii, A., Lenarz, M., Majdani, O., Lim, H. H., Samii, M. & Lenarz, T., Jan 1 2007, In : Otology and Neurotology. 28, 1, p. 31-38 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Dynamic models of neural spiking activity

Czanner, G., Dreyer, A. A., Eden, U. T., Wirth, S., Lim, H. H., Suzuki, W. A. & Brown, E. N., Dec 1 2007, Proceedings of the 46th IEEE Conference on Decision and Control 2007, CDC. p. 5812-5817 6 p. 4434689. (Proceedings of the IEEE Conference on Decision and Control).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Electrical stimulation of the midbrain for hearing restoration: Insight into the functional organization of the human central auditory system

Lim, H. H., Lenarz, T., Joseph, G., Battmer, R. D., Samii, A., Samii, M., Patrick, J. F. & Lenarz, M., Dec 5 2007, In : Journal of Neuroscience. 27, 49, p. 13541-13551 11 p.

Research output: Contribution to journalArticle

49 Scopus citations
32 Scopus citations
2006

Auditory cortical responses to electrical stimulation of the inferior colliculus: Implications for an auditory midbrain implant

Lim, H. H. & Anderson, D. J., Sep 18 2006, In : Journal of neurophysiology. 96, 3, p. 975-988 14 p.

Research output: Contribution to journalArticle

59 Scopus citations

Electrophysiological validation of a human prototype auditory midbrain implant in a guinea pig model

Lenarz, M., Lim, H. H., Patrick, J. F., Anderson, D. J. & Lenarz, T., Dec 1 2006, In : JARO - Journal of the Association for Research in Otolaryngology. 7, 4, p. 383-398 16 p.

Research output: Contribution to journalArticle

30 Scopus citations