1966 …2019
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Research Output 1966 2019

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Review article
2016
11 Citations (Scopus)

Effect of Opioid on Adult Hippocampal Neurogenesis

Zhang, Y., Loh, H. H. & Law, P-Y., Jan 1 2016, In : Scientific World Journal. 2016, 2601264.

Research output: Contribution to journalReview article

Neurogenesis
Opioid Analgesics
Opiate Alkaloids
drug
Pharmaceutical Preparations
11 Citations (Scopus)

Effects of addictive drugs on adult neural stem/progenitor cells

Xu, C., Loh, H. H. & Law, P. Y., Jan 1 2016, In : Cellular and Molecular Life Sciences. 73, 2, p. 327-348 22 p.

Research output: Contribution to journalReview article

Adult Stem Cells
Neural Stem Cells
Stem Cells
Neurogenesis
Pharmaceutical Preparations
2013
34 Citations (Scopus)

Opioid receptors: Toward separation of analgesic from undesirable effects

Law, P-Y., Reggio, P. H. & Loh, H. H., Jun 1 2013, In : Trends in Biochemical Sciences. 38, 6, p. 275-282 8 p.

Research output: Contribution to journalReview article

Opioid Receptors
Opioid Analgesics
Analgesics
Oligomers
Pain Management
2012
28 Citations (Scopus)

MicroRNAs in opioid pharmacology

Hwang, C. K. T., Wagley, Y., Law, P-Y., Wei, L-N. & Loh, H. H., Dec 1 2012, In : Journal of Neuroimmune Pharmacology. 7, 4, p. 808-819 12 p.

Research output: Contribution to journalReview article

MicroRNAs
Opioid Analgesics
Pharmacology
Drug Receptors
Messenger RNA
17 Citations (Scopus)

Non-coding RNAs regulating morphine function: With emphasis on the in vivo and in vitro functions of miR-190

Zheng, H., Law, P. Y. & Loh, H. H., Dec 1 2012, In : Frontiers in Genetics. 3, JUN, Article 113.

Research output: Contribution to journalReview article

Untranslated RNA
Morphine
Opioid Analgesics
Biological Phenomena
Neurogenesis
2010
48 Citations (Scopus)

Agonist-selective signaling of G protein-coupled receptor: Mechanisms and implications

Zheng, H., Loh, H. H. & Law, P. Y., Apr 26 2010, In : IUBMB Life. 62, 2, p. 112-119 8 p.

Research output: Contribution to journalReview article

G-Protein-Coupled Receptors
Arrestin
Biological Phenomena
GTP-Binding Proteins
Ligands
6 Citations (Scopus)

Search for the "ideal analgesic" in pain treatment by engineering the mu-opioid receptor

Tao, P. L., Law, P. Y. & Loh, H. H., Apr 26 2010, In : IUBMB Life. 62, 2, p. 103-111 9 p.

Research output: Contribution to journalReview article

Narcotic Antagonists
mu Opioid Receptor
Analgesics
Pain
Alkaloids
2008
29 Citations (Scopus)

The other side of the Opioid story: Modulation of cell growth and survival signaling

Chen, Y. L., Law, P-Y. & Loh, H. H., Apr 1 2008, In : Current Medicinal Chemistry. 15, 8, p. 772-778 7 p.

Research output: Contribution to journalReview article

Cell growth
Opioid Analgesics
Cell Survival
Modulation
Cell proliferation
2005
94 Citations (Scopus)

Inhibition of P13K/Akt signaling: An emerging paradigm for targeted cancer therapy

Chen, Y. L., Law, P-Y. & Loh, H. H., Nov 2005, In : Current Medicinal Chemistry - Anti-Cancer Agents. 5, 6, p. 575-589 15 p.

Research output: Contribution to journalReview article

Phosphatidylinositol 3-Kinase
Neoplasms
Cell Survival
Therapeutics
Proto-Oncogene Proteins c-akt
2004
29 Citations (Scopus)

Post-transcriptional regulation of opioid receptors in the nervous system

Wei, L. N., Law, P. Y. & Loh, H. H., Jan 1 2004, In : Frontiers in Bioscience. 9, p. 1665-1679 15 p.

Research output: Contribution to journalReview article

Neurology
Opioid Receptors
Nervous System
Genes
Messenger RNA
2002
55 Citations (Scopus)

Regulation of opioid receptor expression

Wei, L-N. & Loh, H. H., Feb 1 2002, In : Current Opinion in Pharmacology. 2, 1, p. 69-75 7 p.

Research output: Contribution to journalReview article

Opioid Receptors
Genes
Nucleic Acid Regulatory Sequences
RNA Stability
Alternative Splicing
2000
496 Citations (Scopus)

Molecular mechanisms and regulation of opioid receptor signaling

Law, P. Y., Wong, Y. H. & Loh, H. H., Jun 20 2000, In : Annual Review of Pharmacology and Toxicology. 40, p. 389-430 42 p.

Research output: Contribution to journalReview article

Opioid Receptors
Genes
Cloning
Gene Expression Regulation
Gene expression
1996
3 Citations (Scopus)

Regulation of acute and chronic opioid receptor functions by OBCAM, a cell adhesion-like molecule.

Loh, H. H. & Smith, A. P., 1996, In : NIDA research monograph. 161, p. 141-153 13 p.

Research output: Contribution to journalReview article

Nerve Tissue Proteins
Narcotics
Cell Adhesion Molecules
Molecular Cloning
Opioid Receptors
1983
36 Citations (Scopus)

The multiple site β-endorphin receptor

Smith, A. P., Lee, N. M. & Loh, H. H., 1983, In : Trends in Pharmacological Sciences. 4, C, p. 163-164 2 p.

Research output: Contribution to journalReview article

Opioid Receptors
1982
4 Citations (Scopus)

Opioid peptide receptors and membrane biology.

Smith, A. P. & Loh, H. H., Dec 1 1982, In : Progress in clinical and biological research. 97, p. 113-135 23 p.

Research output: Contribution to journalReview article

Peptide Receptors
Opioid Peptides
Enkephalins
Opioid Receptors
Alkaloids
1980
168 Citations (Scopus)

The role of membrane lipids in receptor mechanisms.

Loh, H. H. & Law, P. Y., 1980, In : Annual review of pharmacology and toxicology. 20, p. 201-234 34 p.

Research output: Contribution to journalReview article

Drug Receptors
Gangliosides
Cholera Toxin
Cell Surface Receptors
Opioid Receptors
1979
11 Citations (Scopus)

A proposed mode of action for narcotic agonists and antagonists.

Cho, T. M., Law, P. Y. & Loh, H. H., Jan 1 1979, In : Advances in biochemical psychopharmacology. 20, p. 69-101 33 p.

Research output: Contribution to journalReview article

Physical Chemistry
Cerebrosides
Biological Models
Molecular Models
Narcotic Antagonists
33 Citations (Scopus)

Endorphin-opiate interactions with neuroendocrine systems.

Holaday, J. W. & Loh, H. H., Jan 1 1979, In : Advances in biochemical psychopharmacology. 20, p. 227-258 32 p.

Research output: Contribution to journalReview article

Opiate Alkaloids
Hypothalamo-Hypophyseal System
Anterior Pituitary Hormones
Hypothalamic Hormones
Drug Tolerance
8 Citations (Scopus)

Influence of morphine on membrane turnover and function.

Hitzemann, R., Natsuki, R., Ohizumi, Y., Johnson, D. & Loh, H., Jan 1 1979, In : Advances in biochemical psychopharmacology. 20, p. 495-520 26 p.

Research output: Contribution to journalReview article

Nerve Tissue Proteins
Opioid Receptors
gamma-Aminobutyric Acid
Morphine
Phospholipids
1978
45 Citations (Scopus)

Possible involvement of cerebroside sulfate in opiate receptor binding

Loh, H. H., Law, P. Y., Ostwald, T., Cho, T. M. & Way, E. L., Dec 11 1978, In : Federation Proceedings. 37, 2, p. 147-152 6 p.

Research output: Contribution to journalReview article

Opioid Receptors
Opiate Alkaloids
Brain
Narcotics
cerebroside sulfate
1977
6 Citations (Scopus)

Alterations of macromolecule biosynthesis after chronic administration of opiates and ethanol.

Loh, H. H., Lee, N. M. & Harris, R. A., Dec 1 1977, In : Advances in experimental medicine and biology. 85 B, p. 65-86 22 p.

Research output: Contribution to journalReview article

Opiate Alkaloids
Biosynthesis
Macromolecules
Ethanol
Morphine