1966 …2019

Research output per year

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2001

Phosphorylation of Ser363, Thr370, and Ser 375 Residues within the Carboxyl Tail Differentially Regulates μ-Opioid Receptor Internalization

El Kouhen, R., Burd, A. L., Erickson-Herbrandson, L. J., Chang, C. Y., Law, P-Y. & Loh, H. H., Apr 20 2001, In : Journal of Biological Chemistry. 276, 16, p. 12774-12780 7 p.

Research output: Contribution to journalArticle

104 Scopus citations

Region specific increase of dopamine receptor D1/D2 mRNA expression in the brain of μ-opioid receptor knockout mice

Park, Y., Kang Ho, I., Fan, L. W., Loh, H. H. & Ko, K. H., Mar 16 2001, In : Brain Research. 894, 2, p. 311-315 5 p.

Research output: Contribution to journalArticle

31 Scopus citations

Regulation of mouse κ opioid receptor gene expression by retinoids

Bi, J., Hu, X., Loh, H. H. & Wei, L. N., Mar 1 2001, In : Journal of Neuroscience. 21, 5, p. 1590-1599 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

Role of hypothalamic-pituitary axis in morphine-induced alteration in thymic cell distribution using mu-opioid receptor knockout mice

Roy, S., Wang, J. H., Balasubramanian, S., Sumandeep, Charboneau, R., Barke, R. & Loh, H. H., Jun 1 2001, In : Journal of Neuroimmunology. 116, 2, p. 147-155 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Role of mu-opioid receptor in immune function

Roy, S., Charboneau, R. G., Barke, R. A. & Loh, H. H., Dec 1 2001, In : Advances in Experimental Medicine and Biology. 493, p. 117-126 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

Single-stranded DNA-binding complex involved in transcriptional regulation of mouse μ-opioid receptor gene

Ko, J. L. & Loh, H. H., Jan 5 2001, In : Journal of Biological Chemistry. 276, 1, p. 788-795 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

Transcriptional modulation of mouse μ-opioid receptor distal promoter activity by Sox18

Im, H. J., Smirnov, D., Yuhi, T., Raghavan, S., Olsson, J. E., Muscat, G. E., Koopman, P. & Loh, H. H., Jan 1 2001, In : Molecular Pharmacology. 59, 6, p. 1486-1496 11 p.

Research output: Contribution to journalArticle

17 Scopus citations
20 Scopus citations

δ-opioid receptor gene: Effect of Sp1 factor on transcriptional regulation in vivo

Smirnov, D., Im, H. J. & Loh, H. H., Jan 1 2001, In : Molecular Pharmacology. 60, 2, p. 331-340 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

μ-Opioid receptor gene expression: The role of NCAM

Chen, H. C. & Loh, H. H., Dec 5 2001, In : Neuroscience. 108, 1, p. 7-15 9 p.

Research output: Contribution to journalArticle

8 Scopus citations
2002

A novel signaling pathway of nitric oxide on transcriptional regulation of mouse κ opioid receptor gene

Park, S. W., Li, J., Loh, H. H. & Wei, L-N., Sep 15 2002, In : Journal of Neuroscience. 22, 18, p. 7941-7947 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

Differential promoter usage of mouse mu-opioid receptor gene during development.

Ko, J. L., Chen, H. C. & Loh, H. H., Aug 15 2002, In : Brain research. Molecular brain research. 104, 2, p. 184-193 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Induction of the mouse κ-opioid receptor gene by retinoic acid in p19 cells

Li, J., Park, S. W., Loh, H. H. & Wei, L. N., Oct 18 2002, In : Journal of Biological Chemistry. 277, 42, p. 39967-39972 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

Loss of μ-opioid receptor-mediated G-protein activation in the pons/medulla of mice lacking the exons 2 and 3 of μ-opioid receptor gene

Mizoguchi, H., Wu, H. E., Narita, M., Loh, H. H., Nagase, H. & Tseng, L. F., Dec 25 2002, In : Neuroscience Letters. 335, 2, p. 91-94 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Regulation of mouse κ opioid receptor gene expression by different 3′-untranslated regions and the effect of retinoic acid

Hu, X., Bi, J., Loh, H. H. & Wei, L-N., Oct 1 2002, In : Molecular Pharmacology. 62, 4, p. 881-887 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Rewarding effects of ethanol and cocaine in μ opioid receptor-deficient mice

Becker, A., Grecksch, G., Kraus, J., Loh, H. H., Schroeder, H. & Höllt, V., Apr 16 2002, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 365, 4, p. 296-302 7 p.

Research output: Contribution to journalArticle

99 Scopus citations

The immunosuppressive effects of chronic morphine treatment are partially dependent on corticosterone and mediated by the μ-opioid receptor

Wang, J., Charboneau, R., Balasubramanian, S., Barke, R. A., Loh, H. H. & Roy, S., May 1 2002, In : Journal of Leukocyte Biology. 71, 5, p. 782-790 9 p.

Research output: Contribution to journalArticle

77 Scopus citations

The interaction of morphine and γ-aminobutyric acid (GABA)ergic systems in anxiolytic behavior: Using μ-opioid receptor knockout mice

Sasaki, K., Fan, L. W., Tien, L. T., Ma, T., Loh, H. H. & Ho, I. K., Mar 15 2002, In : Brain Research Bulletin. 57, 5, p. 689-694 6 p.

Research output: Contribution to journalArticle

57 Scopus citations
19 Scopus citations

μ-opioid receptor mediates chronic restraint stress-induced lymphocyte apoptosis

Wang, J., Charboneau, R., Barke, R. A., Loh, H. H. & Roy, S., Oct 1 2002, In : Journal of Immunology. 169, 7, p. 3630-3636 7 p.

Research output: Contribution to journalArticle

68 Scopus citations
2003

Differential effects of morphine and cocaine on locomotor activity and sensitization in μ-opioid receptor knockout mice

Yoo, J. H., Yang, E. M., Lee, S. Y., Loh, H. H., Ho, I. K. & Jang, C. G., Jun 19 2003, In : Neuroscience Letters. 344, 1, p. 37-40 4 p.

Research output: Contribution to journalArticle

44 Scopus citations

DPDPE-UK14,304 synergy is retained in mu opioid receptor knockout mice

Guo, X. H., Fairbanks, C. A., Stone, L. S. & Loh, H. H., Jul 2003, In : Pain. 104, 1-2, p. 209-217 9 p.

Research output: Contribution to journalArticle

26 Scopus citations
1 Scopus citations

Impaired water maze learning performance in μ-opioid receptor knockout mice

Jang, C. G., Lee, S. Y., Yoo, J. H., Yan, J. J., Song, D. K., Loh, H. H. & Ho, I. K., Sep 10 2003, In : Molecular Brain Research. 117, 1, p. 68-72 5 p.

Research output: Contribution to journalArticle

30 Scopus citations

Increased dopamine D2 receptor binding and enhanced apomorphine-induced locomotor activity in μ-opioid receptor knockout mice

Tien, L. T., Park, Y., Fan, L. W., Ma, T., Loh, H. H. & Ho, I. K., Jun 30 2003, In : Brain Research Bulletin. 61, 1, p. 109-115 7 p.

Research output: Contribution to journalArticle

30 Scopus citations
17 Scopus citations

Lack of μ-opioid receptor-mediated G-protein activation in the spinal cord of mice lacking exon 1 or exons 2 and 3 of the MOR-1 gene

Mizoguchi, H., Wu, H. E., Narita, M., Sora, I., Hall, F. S., Uhl, G. R., Loh, H. H., Nagase, H. & Tseng, L. F., Dec 1 2003, In : Journal of Pharmacological Sciences. 93, 4, p. 423-429 7 p.

Research output: Contribution to journalArticle

19 Scopus citations
22 Scopus citations

Morphine negatively regulates interferon-γ promoter activity in activated murine T cells through two distinct cyclic AMP-dependent pathways

Wang, J., Barke, R. A., Charboneau, R., Loh, H. H. & Roy, S., Sep 26 2003, In : Journal of Biological Chemistry. 278, 39, p. 37622-37631 10 p.

Research output: Contribution to journalArticle

70 Scopus citations

Mouse κ-opioid receptor mRNA differential transport in neurons

Bi, J., Hu, X., Loh, H. H. & Wei, L-N., Sep 1 2003, In : Molecular Pharmacology. 64, 3, p. 594-599 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Mouse μ opioid receptor distal promoter transcriptional regulation by SOX proteins

Hwang, C. K., Wu, X., Wang, G., Kim, C. S. & Loh, H. H., Feb 7 2003, In : Journal of Biological Chemistry. 278, 6, p. 3742-3750 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Mu and delta receptors mediate morphine effects on phagocytosis by murine peritoneal macrophages

Tomassini, N., Renaud, F. L., Roy, S. & Loh, H. H., Mar 2003, In : Journal of Neuroimmunology. 136, 1-2, p. 9-16 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Regional specific increases of [3H]AMPA binding and mRNA expression of AMPA receptors in the brain of μ-opioid receptor knockout mice

Park, Y., Jang, C. G., Yang, K. H., Loh, H. H., Ma, T. & Ho, I. K., May 12 2003, In : Molecular Brain Research. 113, 1-2, p. 116-123 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Rescuing the traffic-deficient mutants of rat μ-opioid receptors with hydrophobic ligands

Chaipatikul, V., Erickson-Herbrandson, L. J., Loh, H. H. & Law, P. Y., Jul 1 2003, In : Molecular Pharmacology. 64, 1, p. 32-41 10 p.

Research output: Contribution to journalArticle

40 Scopus citations

Role of an AP-2-like element in transcriptional regulation of mouse μ-opioid receptor gene

Ko, J. L., Liu, H. C. & Loh, H. H., Apr 10 2003, In : Molecular Brain Research. 112, 1-2, p. 153-162 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

The first and third intracellular loops together with the carboxy terminal tail of the δ-opioid receptor contribute toward functional interaction with Gα16

Chan, A. S. L., Law, P. Y., Loh, H. H., Ho, P. N. N., Wu, W. M., Chan, J. S. C. & Wong, Y. H., Nov 1 2003, In : Journal of Neurochemistry. 87, 3, p. 697-708 12 p.

Research output: Contribution to journalArticle

13 Scopus citations

The intracellular trafficking of opioid receptors directed by carboxyl tail and a di-leucine motif in Neuro2A cells

Wang, W., Loh, H. H. & Law, P-Y., Sep 19 2003, In : Journal of Biological Chemistry. 278, 38, p. 36848-36858 11 p.

Research output: Contribution to journalArticle

34 Scopus citations
12 Scopus citations
26 Scopus citations

μ-opioid receptor desensitization: Role of receptor phosphorylation, internalization, and resensitization

Qiu, Y., Law, P. Y. & Loh, H. H., Sep 19 2003, In : Journal of Biological Chemistry. 278, 38, p. 36733-36739 7 p.

Research output: Contribution to journalArticle

68 Scopus citations
2004

Accelerated kindling development in μ-opioid receptor deficient mice

Grecksch, G., Becker, A., Schroeder, H., Kraus, J., Loh, H. & Höllt, V., Mar 1 2004, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 369, 3, p. 287-293 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Altered emotional behaviors and the expression of 5-HT 1A and M 1 muscarinic receptors in μ-opioid receptor knockout mice

Yoo, J. I. H., Lee, S. Y., Loh, H. H., Ho, I. K. & Jang, C. G., Nov 1 2004, In : Synapse. 54, 2, p. 72-82 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

Changes in acetylcholinesterase activity and muscarinic receptor bindings in μ-opioid receptor knockout mice

Tien, L. T., Fan, L. W., Sogawa, C., Ma, T., Loh, H. H. & Ho, I. K., Jul 5 2004, In : Molecular Brain Research. 126, 1, p. 38-44 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Chronic morphine treatment differentiates T helper cells to Th2 effector cells by modulating transcription factors GATA 3 and T-bet

Roy, S., Wang, J., Gupta, S., Charboneau, R., Loh, H. H. & Barke, R. A., Feb 2004, In : Journal of Neuroimmunology. 147, 1-2, p. 78-81 4 p.

Research output: Contribution to journalArticle

67 Scopus citations

Increased diisopropylfluorophosphate-induced toxicity in μ-opioid receptor knockout mice

Tien, L. T., Fan, L. W., Ma, T., Loh, H. H. & Ho, I. K., Oct 15 2004, In : Journal of Neuroscience Research. 78, 2, p. 259-267 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Inhibition of Akt/protein kinase B signaling by naltrindole in small cell lung cancer cells

Chen, Y. L., Law, P-Y. & Loh, H. H., Dec 1 2004, In : Cancer Research. 64, 23, p. 8723-8730 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

Insights into the receptor transcription and signaling: Implications in opioid tolerance and dependence

Law, P. Y., Loh, H. H. & Wei, L. N., Jan 1 2004, In : Neuropharmacology. 47, SUPPL. 1, p. 300-311 12 p.

Research output: Contribution to journalArticle

73 Scopus citations

Loss of Nicotine-Induced Behavioral Sensitization in μ-Opioid Receptor Knockout Mice

Yoo, J. H., Lee, S. Y., Loh, H. H., Ho, I. K. & Jang, C. G., Mar 15 2004, In : Synapse. 51, 4, p. 219-223 5 p.

Research output: Contribution to journalArticle

25 Scopus citations

Morphine inhibits Fc-mediated phagocytosis through mu and delta opioid receptors

Tomassini, N., Renaud, F., Roy, S. & Loh, H. H., Feb 2004, In : Journal of Neuroimmunology. 147, 1-2, p. 131-133 3 p.

Research output: Contribution to journalArticle

24 Scopus citations

Neuron-restrictive Silencer Factor (NRSF) functions as a repressor in neuronal cells to regulate the μ opioid receptor gene

Chun, S. K., Cheol, K. H., Hack, S. C., Kyu, Y. S., Law, P. Y., Wei, L. N. & Loh, H. H., Nov 5 2004, In : Journal of Biological Chemistry. 279, 45, p. 46464-46473 10 p.

Research output: Contribution to journalArticle

68 Scopus citations