1966 …2019

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2003

Role of an AP-2-like element in transcriptional regulation of mouse μ-opioid receptor gene

Ko, J. L., Liu, H. C. & Loh, H. H., Apr 10 2003, In : Molecular Brain Research. 112, 1-2, p. 153-162 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

The first and third intracellular loops together with the carboxy terminal tail of the δ-opioid receptor contribute toward functional interaction with Gα16

Chan, A. S. L., Law, P. Y., Loh, H. H., Ho, P. N. N., Wu, W. M., Chan, J. S. C. & Wong, Y. H., Nov 1 2003, In : Journal of Neurochemistry. 87, 3, p. 697-708 12 p.

Research output: Contribution to journalArticle

13 Scopus citations

The intracellular trafficking of opioid receptors directed by carboxyl tail and a di-leucine motif in Neuro2A cells

Wang, W., Loh, H. H. & Law, P-Y., Sep 19 2003, In : Journal of Biological Chemistry. 278, 38, p. 36848-36858 11 p.

Research output: Contribution to journalArticle

34 Scopus citations
12 Scopus citations
26 Scopus citations

μ-opioid receptor desensitization: Role of receptor phosphorylation, internalization, and resensitization

Qiu, Y., Law, P. Y. & Loh, H. H., Sep 19 2003, In : Journal of Biological Chemistry. 278, 38, p. 36733-36739 7 p.

Research output: Contribution to journalArticle

68 Scopus citations
2002

A novel signaling pathway of nitric oxide on transcriptional regulation of mouse κ opioid receptor gene

Park, S. W., Li, J., Loh, H. H. & Wei, L-N., Sep 15 2002, In : Journal of Neuroscience. 22, 18, p. 7941-7947 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

Differential promoter usage of mouse mu-opioid receptor gene during development.

Ko, J. L., Chen, H. C. & Loh, H. H., Aug 15 2002, In : Brain research. Molecular brain research. 104, 2, p. 184-193 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Induction of the mouse κ-opioid receptor gene by retinoic acid in p19 cells

Li, J., Park, S. W., Loh, H. H. & Wei, L. N., Oct 18 2002, In : Journal of Biological Chemistry. 277, 42, p. 39967-39972 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

Loss of μ-opioid receptor-mediated G-protein activation in the pons/medulla of mice lacking the exons 2 and 3 of μ-opioid receptor gene

Mizoguchi, H., Wu, H. E., Narita, M., Loh, H. H., Nagase, H. & Tseng, L. F., Dec 25 2002, In : Neuroscience Letters. 335, 2, p. 91-94 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Regulation of mouse κ opioid receptor gene expression by different 3′-untranslated regions and the effect of retinoic acid

Hu, X., Bi, J., Loh, H. H. & Wei, L-N., Oct 1 2002, In : Molecular Pharmacology. 62, 4, p. 881-887 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Rewarding effects of ethanol and cocaine in μ opioid receptor-deficient mice

Becker, A., Grecksch, G., Kraus, J., Loh, H. H., Schroeder, H. & Höllt, V., Apr 16 2002, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 365, 4, p. 296-302 7 p.

Research output: Contribution to journalArticle

98 Scopus citations

The immunosuppressive effects of chronic morphine treatment are partially dependent on corticosterone and mediated by the μ-opioid receptor

Wang, J., Charboneau, R., Balasubramanian, S., Barke, R. A., Loh, H. H. & Roy, S., May 1 2002, In : Journal of Leukocyte Biology. 71, 5, p. 782-790 9 p.

Research output: Contribution to journalArticle

77 Scopus citations

The interaction of morphine and γ-aminobutyric acid (GABA)ergic systems in anxiolytic behavior: Using μ-opioid receptor knockout mice

Sasaki, K., Fan, L. W., Tien, L. T., Ma, T., Loh, H. H. & Ho, I. K., Mar 15 2002, In : Brain Research Bulletin. 57, 5, p. 689-694 6 p.

Research output: Contribution to journalArticle

55 Scopus citations
19 Scopus citations

μ-opioid receptor mediates chronic restraint stress-induced lymphocyte apoptosis

Wang, J., Charboneau, R., Barke, R. A., Loh, H. H. & Roy, S., Oct 1 2002, In : Journal of Immunology. 169, 7, p. 3630-3636 7 p.

Research output: Contribution to journalArticle

68 Scopus citations
2001

Affinity labels as tools for the identification of opioid receptor recognition sites

Portoghese, P. S., El Kouhen, R., Law, P. Y., Loh, H. H. & Le Bourdonnec, B., Apr 1 2001, In : Farmaco. 56, 3, p. 191-196 6 p.

Research output: Contribution to journalArticle

11 Scopus citations
29 Scopus citations

Differential effects of morphine, DPDPE, and U-50488 on apomorphine-induced climbing behavior in μ-opioid receptor knockout mice

Jang, C. G., Lee, S. Y., Park, Y., Ma, T., Loh, H. H. & Ho, I. K., Oct 19 2001, In : Molecular Brain Research. 94, 1-2, p. 197-199 3 p.

Research output: Contribution to journalArticle

12 Scopus citations

Effects of morphine on pentobarbital-induced responses in μ-opioid receptor knockout mice

Park, Y., Ho, I. K., Jang, C. G., Tanaka, S., Ma, T., Loh, H. H. & Ko, K. H., Mar 15 2001, In : Brain Research Bulletin. 54, 5, p. 527-531 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Lack of μ-opioid receptor leads to an increase in the NMDA receptor subunit mRNA expression and NMDA-induced convulsion

Jang, C. G., Lee, S. Y., Loh, H. H. & Ho, I. K., Oct 19 2001, In : Molecular Brain Research. 94, 1-2, p. 105-111 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Morphine modulates lymph node-derived T lymphocyte function: Role of caspase-3, -8, and nitric oxide

Wang, J., Charboneau, R., Balasubramanian, S., Barke, R. A., Loh, H. H. & Roy, S., Oct 22 2001, In : Journal of Leukocyte Biology. 70, 4, p. 527-536 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

Opioid and cannabinoid modulation of precipitated withdrawal in δ9-tetrahydrocannabinol and morphine-dependent mice

Lichtman, A. H., Sheikh, S. M., Loh, H. H. & Martin, B. R., Aug 29 2001, In : Journal of Pharmacology and Experimental Therapeutics. 298, 3, p. 1007-1014 8 p.

Research output: Contribution to journalArticle

122 Scopus citations

Phosphorylation of Ser363, Thr370, and Ser 375 Residues within the Carboxyl Tail Differentially Regulates μ-Opioid Receptor Internalization

El Kouhen, R., Burd, A. L., Erickson-Herbrandson, L. J., Chang, C. Y., Law, P-Y. & Loh, H. H., Apr 20 2001, In : Journal of Biological Chemistry. 276, 16, p. 12774-12780 7 p.

Research output: Contribution to journalArticle

103 Scopus citations

Region specific increase of dopamine receptor D1/D2 mRNA expression in the brain of μ-opioid receptor knockout mice

Park, Y., Kang Ho, I., Fan, L. W., Loh, H. H. & Ko, K. H., Mar 16 2001, In : Brain Research. 894, 2, p. 311-315 5 p.

Research output: Contribution to journalArticle

31 Scopus citations

Regulation of mouse κ opioid receptor gene expression by retinoids

Bi, J., Hu, X., Loh, H. H. & Wei, L. N., Mar 1 2001, In : Journal of Neuroscience. 21, 5, p. 1590-1599 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

Role of hypothalamic-pituitary axis in morphine-induced alteration in thymic cell distribution using mu-opioid receptor knockout mice

Roy, S., Wang, J. H., Balasubramanian, S., Sumandeep, Charboneau, R., Barke, R. & Loh, H. H., Jun 1 2001, In : Journal of Neuroimmunology. 116, 2, p. 147-155 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Role of mu-opioid receptor in immune function

Roy, S., Charboneau, R. G., Barke, R. A. & Loh, H. H., Dec 1 2001, In : Advances in Experimental Medicine and Biology. 493, p. 117-126 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

Single-stranded DNA-binding complex involved in transcriptional regulation of mouse μ-opioid receptor gene

Ko, J. L. & Loh, H. H., Jan 5 2001, In : Journal of Biological Chemistry. 276, 1, p. 788-795 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

Transcriptional modulation of mouse μ-opioid receptor distal promoter activity by Sox18

Im, H. J., Smirnov, D., Yuhi, T., Raghavan, S., Olsson, J. E., Muscat, G. E., Koopman, P. & Loh, H. H., Jan 1 2001, In : Molecular Pharmacology. 59, 6, p. 1486-1496 11 p.

Research output: Contribution to journalArticle

17 Scopus citations
20 Scopus citations

δ-opioid receptor gene: Effect of Sp1 factor on transcriptional regulation in vivo

Smirnov, D., Im, H. J. & Loh, H. H., Jan 1 2001, In : Molecular Pharmacology. 60, 2, p. 331-340 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

μ-Opioid receptor gene expression: The role of NCAM

Chen, H. C. & Loh, H. H., Dec 5 2001, In : Neuroscience. 108, 1, p. 7-15 9 p.

Research output: Contribution to journalArticle

8 Scopus citations
2000

An autoradiographic study in μ-opioid receptor knockout mice

Chen, H. C., Seybold, V. S. & Loh, H. H., Mar 10 2000, In : Molecular Brain Research. 76, 1, p. 170-172 3 p.

Research output: Contribution to journalArticle

12 Scopus citations

Association of a lower molecular weight protein to the μ-opioid receptor demonstrated by 125I-β-endorphin cross-linking studies

Law, P-Y., Tine, S. J., McLeod, L. A. & Loh, H. H., Jul 11 2000, In : Journal of Neurochemistry. 75, 1, p. 164-173 10 p.

Research output: Contribution to journalArticle

5 Scopus citations
27 Scopus citations

Comparison of G-protein activation in the brain by μ-, δ-, and κ-opioid receptor agonists in μ-opioid receptor knockout mice

Park, Y., Ma, T., Tanaka, S., Jang, C. G., Loh, H. H., Ko, K. H. & Ho, I. K., Jul 1 2000, In : Brain Research Bulletin. 52, 4, p. 297-302 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

Deltorphin II-induced rapid desensitization of δ-opioid receptor requires both phosphorylation and internalization of the receptor

Law, P-Y., Maestri-El Kouhen, O., Solberg, J., Wang, W., Erickson, L. J. & Loh, H. H., Oct 13 2000, In : Journal of Biological Chemistry. 275, 41, p. 32057-32065 9 p.

Research output: Contribution to journalArticle

61 Scopus citations

Hierarchical phosphorylation of δ-opioid receptor regulates agonist-induced receptor desensitization and internalization

Kouhen, O. M. E., Wang, G., Solberg, J., Erickson, L. J., Law, P-Y. & Loh, H. H., Nov 24 2000, In : Journal of Biological Chemistry. 275, 47, p. 36659-36664 6 p.

Research output: Contribution to journalArticle

65 Scopus citations

Involvement of μ-opioid receptors in potentiation of apomorphine-induced climbing behavior by morphine: studies using μ-opioid receptor gene knockout mice

Jang, C. G., Park, Y., Tanaka, S., Ma, T., Loh, H. H. & Ho, I. K., May 31 2000, In : Molecular Brain Research. 78, 1-2, p. 204-206 3 p.

Research output: Contribution to journalArticle

13 Scopus citations

Lack of expression of long-term potentiation in the dentate gyrus but not in the CA1 region of the hippocampus of μ-opioid receptor-deficient mice

Matthies, H., Schroeder, H., Becker, A., Loh, H., Höllt, V. & Krug, M., May 1 2000, In : Neuropharmacology. 39, 6, p. 952-960 9 p.

Research output: Contribution to journalArticle

34 Scopus citations

Morphine self-administration in μ-opioid receptor-deficient mice

Becker, A., Grecksch, G., Brödemann, R., Kraus, J., Peters, B., Schroeder, H., Thiemann, W., Loh, H. H. & Höllt, V., Jun 24 2000, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 361, 6, p. 584-589 6 p.

Research output: Contribution to journalArticle

67 Scopus citations

Post-transcriptional regulation of mouse κ-opioid receptor expression

Wei, L-N., Hu, X., Bi, J. & Loh, H. H., Feb 17 2000, In : Molecular Pharmacology. 57, 2, p. 401-408 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

Receptor density and recycling affect the rate of agonist-induced desensitization of μ-opioid receptor

Law, P-Y., Erickson, L. J., El-Kouhen, R., Dicker, L., Solberg, J., Wang, W., Miller, E., Burd, A. L. & Loh, H. H., Jan 1 2000, In : Molecular Pharmacology. 58, 2, p. 388-398 11 p.

Research output: Contribution to journalArticle

91 Scopus citations
1999

Altered adenylyl cyclase responsiveness subsequent to point mutations of Asp 128 in the third transmembrane domain of the δ-opioid receptor

Cavalli, A., Babey, A. M. & Loh, H. H., Aug 1 1999, In : Neuroscience. 93, 3, p. 1025-1031 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Expression of μ-, κ- and δ-opioid receptors in P19 mouse embryonal carcinoma cells

Chen, H. C., Wei, L-N. & Loh, H. H., Jun 1 1999, In : Neuroscience. 92, 3, p. 1143-1155 13 p.

Research output: Contribution to journalArticle

32 Scopus citations

Mutational analysis of the structure and function of opioid receptors

Law, P. Y., Wong, Y. H. & Loh, H. H., Dec 1 1999, In : Biopolymers - Peptide Science Section. 51, 6, p. 440-455 16 p.

Research output: Contribution to journalArticle

57 Scopus citations

Opioid receptor gene: Cytokine response element and the effect of cytokines

Im, H. J., Kang, S. W. & Loh, H. H., May 22 1999, In : Brain Research. 829, 1-2, p. 174-179 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Promoter activity of mouse κ opioid receptor gene in transgenic mouse

Hu, X., Cao, S., Loh, H. H. & Wei, L-N., May 21 1999, In : Molecular Brain Research. 69, 1, p. 35-43 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Regulation of opioid receptor activities

Law, P. Y. & Loh, H. H., May 1 1999, In : Journal of Pharmacology and Experimental Therapeutics. 289, 2, p. 607-624 18 p.

Research output: Contribution to journalArticle

177 Scopus citations