1966 …2019

Research output per year

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Research Output

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Differential expression of opioid receptor genes in human lymphoid cell lines and peripheral blood lymphocytes

Wick, M. J., Minnerath, S. R., Roy, S., Ramakrishnan, S. & Loh, H. H., Jan 1 1996, In : Journal of Neuroimmunology. 64, 1, p. 29-36 8 p.

Research output: Contribution to journalArticle

74 Scopus citations

Differential gene expression activity among species-specific polypyrimidine/polypurine motifs in mu opioid receptor gene promoters

Choe, C. Y., Dong, J., Law, P-Y. & Loh, H. H., Jan 15 2011, In : Gene. 471, 1-2, p. 27-36 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Differential modulation of drug-induced structural and functional plasticity of dendritic spines

Miller, E. C., Zhang, L., Dummer, B. W., Cariveau, D. R., Loh, H. H., Law, P-Y. & Liao, D., Aug 1 2012, In : Molecular Pharmacology. 82, 2, p. 333-343 11 p.

Research output: Contribution to journalArticle

21 Scopus citations

Differential promoter usage of mouse mu-opioid receptor gene during development.

Ko, J. L., Chen, H. C. & Loh, H. H., Aug 15 2002, In : Brain research. Molecular brain research. 104, 2, p. 184-193 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Differential use of an in-frame translation initiation codon regulates human mu opioid receptor (OPRM1)

Song, K. Y., Choi, H. S., Hwang, C. K. T., Kim, C. S., Law, P-Y., Wei, L-N. & Loh, H. H., Sep 1 2009, In : Cellular and Molecular Life Sciences. 66, 17, p. 2933-2942 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Different molecular weight forms of opioid receptors revealed by polyclonal antibodies

Roy, S., Zhu, Y. X., Lee, N. M. & Loh, H. H., Jan 15 1988, In : Biochemical and Biophysical Research Communications. 150, 1, p. 237-244 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Discovery, structure-activity relationship studies, and anti-nociceptive effects of 1-phenyl-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one as novel opioid receptor agonists

Cheng, M. F., Ou, L. C., Chen, S. C., Chang, W. T., Law, P-Y., Loh, H. H., Chao, Y. S., Shih, C., Yeh, S. H. & Ueng, S. H., Sep 1 2014, In : Bioorganic and Medicinal Chemistry. 22, 17, p. 4694-4703 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Discovery, structure-activity relationship studies, and anti-nociceptive effects of N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamides as novel opioid receptor agonists

Chen, S. R., Ke, Y. Y., Yeh, T. K., Lin, S. Y., Ou, L. C., Chen, S. C., Chang, W. T., Chang, H. F., Wu, Z. H., Hsieh, C. C., Law, P. Y., Loh, H. H., Shih, C., Lai, Y. K., Yeh, S. H. & Ueng, S. H., Jan 1 2017, In : European Journal of Medicinal Chemistry. 126, p. 202-217 16 p.

Research output: Contribution to journalArticle

6 Scopus citations

Discrete changes in brain calcium with morphine analgesia, tolerance-dependence, and abstinence

Adron Harris, R., Yamamoto, H., Loh, H. H. & Leong Way, E., Feb 1 1977, In : Life Sciences. 20, 3, p. 501-505 5 p.

Research output: Contribution to journalArticle

90 Scopus citations
55 Scopus citations

Distinct effects of individual opioids on the morphology of spines depend upon the internalization of mu opioid receptors

Liao, D., Grigoriants, O. O., Wang, W., Wiens, K., Loh, H. H. & Law, P. Y., Jul 1 2007, In : Molecular and Cellular Neuroscience. 35, 3, p. 456-469 14 p.

Research output: Contribution to journalArticle

40 Scopus citations

Distribution and metabolism of tritiated yohimbine in mice.

Ho, A. K., Hoffman, D. B., Gershon, S. & Loh, H. H., Dec 1 1971, In : Archives internationales de pharmacodynamie et de therapie. 194, 2, p. 304-315 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Distribution and targeting of a μ-opioid receptor (MOR1) in brain and spinal cord

Arvidsson, U., Riedl, M., Chakrabarti, S., Lee, J. H., Nakano, A. H., Dado, R. J., Loh, H. H., Law, P. Y., Wessendorf, M. W. & Elde, R., May 1995, In : Journal of Neuroscience. 15, 5 I, p. 3328-3341 14 p.

Research output: Contribution to journalArticle

Open Access
537 Scopus citations

Distribution of Neuropeptide Receptors: New Views of Peptidergic Neurotransmission Made Possible by Antibodies to Opioid Receptors

ELDE, ROBERT., ARVIDSSON, ULF., RIEDL, MAUREEN., VULCHANOVA, LUCY., LEE, JANGHERN. H., DADO, ROBERT., NAKANO, ALBERT., CHAKRABARTI, SUMITA., ZHANG, XU., LOH, HORACE. H., LAW, PING. Y., HÖKFELT, TOMAS. & WESSENDORF, MARTIN., May 1995, In : Annals of the New York Academy of Sciences. 757, 1, p. 390-404 15 p.

Research output: Contribution to journalArticle

62 Scopus citations

DNA methylation-related chromatin modification in the regulation of mouse δ-opioid receptor gene

Wang, G., Liu, T., Wei, L. N., Law, P. Y. & Loh, H. H., Jun 1 2005, In : Molecular Pharmacology. 67, 6, p. 2032-2039 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Dopaminergic-cholinergic interactions in naloxone-induced circling in morphine-dependent rats with nigral lesions

Iwamoto, E. T., Loh, H. H. & Leong Way, E., Jul 1976, In : European Journal of Pharmacology. 38, 1, p. 39-54 16 p.

Research output: Contribution to journalArticle

8 Scopus citations

Dopaminergic influence on withdrawal jumping behavior in morphine dependent mice

Tseng, L. F., Brase, D. A. & Loh, H. H., Dec 1 1976, In : Research Communications in Chemical Pathology and Pharmacology. 15, 3, p. 435-446 12 p.

Research output: Contribution to journalArticle

9 Scopus citations
117 Scopus citations

DPDPE-UK14,304 synergy is retained in mu opioid receptor knockout mice

Guo, X. H., Fairbanks, C. A., Stone, L. S. & Loh, H. H., Jul 2003, In : Pain. 104, 1-2, p. 209-217 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

dsAAV type 2-mediated gene transfer of MORS196A-EGFP into spinal cord as a pain management paradigm

Chen, S. L., Ma, H. I., Han, J. M., Tao, P. L., Law, P. Y. & Loh, H. H., Dec 11 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 50, p. 20096-20101 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

D-Tryptophan pyrrolase activity in the liver and the intestine of the rat.

Loh, H. H. & Berg, C. P., Oct 1 1972, In : Journal of Nutrition. 102, 10, p. 1331-1339 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Dual excitatory and inhibitory effects of opioids on intracellular calcium in neuroblastoma x glioma hybrid NG108-15 cells

Jin, W., Lee, N. M., Loh, H. H. & Thayer, S. A., Dec 1 1992, In : Molecular Pharmacology. 42, 6, p. 1083-1089 7 p.

Research output: Contribution to journalArticle

101 Scopus citations

Dual promoters of mouse μ-opioid receptor gene

Ko, J. L., Minnerath, S. R. & Loh, H. H., May 19 1997, In : Biochemical and Biophysical Research Communications. 234, 2, p. 351-357 7 p.

Research output: Contribution to journalArticle

54 Scopus citations
11 Scopus citations

Dynorphin: A possible modulatory peptide on morphine or β-endorphin analgesia in mouse

Friedman, H. J., Jen, M. F., Chang, J. K., Lee, N. M. & Loh, H. H., Jan 29 1981, In : European Journal of Pharmacology. 69, 3, p. 357-360 4 p.

Research output: Contribution to journalArticle

126 Scopus citations

Dynorphin(1-10)amide: A potent and selective analog of dynorphin(1-13)

Woo, S., Garzon, J., Sanchez-Blazquez, P., Tulunay, F. C., Chang, J. K. & Loh, H. H., Jan 1 1982, In : Life Sciences. 31, 16-17, p. 1817-1820 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

Dynorphin-(1-13): The effect of in vivo treatment on opiate bindings in vitro

Jen, M. F., Garzon, J., Loh, H. H. & Lee, N. M., Jul 15 1983, In : European Journal of Pharmacology. 91, 1, p. 95-99 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Dynorphin(1-13) improves survival in cats with focal cerebral ischaemia

Baskin, D. S., Hosobuchi, Y., Loh, H. H. & Lee, N. M., Dec 1 1984, In : Nature. 312, 5994, p. 551-552 2 p.

Research output: Contribution to journalArticle

52 Scopus citations

Dynorphin1-13: interaction with other opiate ligand bindings in vitro

Garzón, J., Sánchez-Blázquez, P., Gerhart, J., Loh, H. H. & Lee, N. M., Jun 8 1984, In : Brain Research. 302, 2, p. 392-396 5 p.

Research output: Contribution to journalArticle

20 Scopus citations

Dynorphin A: Inhibitory effect on other opiate ligand bindings in the mouse brain

Garźon, J., Sánchez-Blázquez, P., Gerhart, J., Loh, H. H. & Lee, N. M., Aug 15 1984, In : Biochemical Pharmacology. 33, 16, p. 2609-2614 6 p.

Research output: Contribution to journalArticle

15 Scopus citations
8 Scopus citations

Dynorphin inhibition of the neurotensin contractile activity on the myenteric plexus

Huidobro-Toro, J. P., Zhu, Y. X., Lee, N. M., Loh, H. H. & Way, E. L., Apr 13 1984, In : Journal of Pharmacology and Experimental Therapeutics. 228, 2, p. 293-303 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Dynorphin interaction at the κ-opiate site

Pablo Huidobro-Toro, J., Yoshimura, K., Lee, N. M., Loh, H. H. & Leong Way, E., Jun 19 1981, In : European Journal of Pharmacology. 72, 2-3, p. 265-266 2 p.

Research output: Contribution to journalArticle

99 Scopus citations

Effect of 6-hydroxydopamine on the incorporation of 14C-leucine into rat brain protein

Loh, H. H., Stolman, S. & Lee, C. Y., Oct 15 1971, In : Life Sciences. 10, 20 PART 1, p. 1171-1180 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Effect of acute and chronic ethanol treatment on rat brain phospholipid turnover

Lee, N. M., Friedman, H. J. & Loh, H. H., Jan 1 1980, In : Biochemical Pharmacology. 29, 20, p. 2815-2818 4 p.

Research output: Contribution to journalArticle

32 Scopus citations

Effect of acute morphine administration on the metabolism of brain catecholamines

Loh, H. H., Hitzemann, R. J. & Leong Way, E., Jan 3 1973, In : Life Sciences. 12, 1 PART 1, p. 33-41 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Effect of arylsulfatase treatment on the opiate activity in mouse vas deferens

Sanchez-Blazquez, P., Garzon, J., Lee, N. M. & Loh, H. H., Jan 1 1982, In : Federation Proceedings. 41, 4, p. No. 5548

Research output: Contribution to journalArticle

Effect of Bisimidate Cross-Linking Reagents on Synaptosomal Plasma Membrane

Smith, A. P. & Loh, H. H., Jan 1 1978, In : Biochemistry. 17, 9, p. 1761-1765 5 p.

Research output: Contribution to journalArticle

16 Scopus citations
23 Scopus citations

Effect of chronic morphine treatment on brain chromatin template activities in mice

Lee, N. M., Ho, I. K. & Loh, H. H., Nov 1 1975, In : Biochemical Pharmacology. 24, 21, p. 1983-1987 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

Effect of clonidine on naloxone induced withdrawal in morphine dependent rats

Tseng, L. F., Wei, E., Loh, H. H. & Ellman, G. L., Jan 1 1974, In : Federation Proceedings. 33, 3 I, 1 p.

Research output: Contribution to journalArticle

Effect of Cyclic AMP on morphine analgesia tolerance and physical dependence

Ho, I. K., Loh, H. H. & Way, E. L., Dec 1 1972, In : Nature. 238, 5364, p. 397-398 2 p.

Research output: Contribution to journalArticle

21 Scopus citations

Effect of cyclic nucleotides and phosphodiesterase inhibition on morphine tolerance and physical dependence

Ho, I. K., Loh, H. H., Bhargava, H. N. & Leong Way, E., Jun 15 1975, In : Life Sciences. 16, 12, p. 1895-1900 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

Effect of dactinomycin on the acute toxicity and brain uptake of morphine.

Loh, H. H., Shen, F. H. & Way, E. L., May 1 1971, In : Journal of Pharmacology and Experimental Therapeutics. 177, 2, p. 326-331 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Effect of d-amphetamine on brain protein synthesis

Loh, H., Hitzemann, R. & Stolman, S., Nov 1973, In : Toxicology and Applied Pharmacology. 26, 3, p. 476-481 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Effect of d-amphetamine on the turnover, synthesis and metabolism of brain phosphatidylcholine

Hitzemann, R. J. & Loh, H. H., Nov 1 1973, In : Biochemical Pharmacology. 22, 21, p. 2731-2741 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Effect of dynorphin-(1-13) and related peptides on respiratory rate and morphine-induced respiratory rate depression

Woo, S. K., Tulunay, F. C., Loh, H. H. & Lee, N. M., Dec 9 1983, In : European Journal of Pharmacology. 96, 1-2, p. 117-122 6 p.

Research output: Contribution to journalArticle

26 Scopus citations

Effect of gamma aminobutyric acid (GABA) on morphine analgesia, tolerance and physical dependence

Ho, I. K., Loh, H. H. & Way, E. L., Jan 1 1973, In : Federation Proceedings. 32, 3 (I), 1 p.

Research output: Contribution to journalArticle

6 Scopus citations

Effect of L 2,4 diaminobutyric acid and β alanine on morphine analgesia, tolerance and physical dependence

Ho, I. K. & Loh, H. H., Jan 1 1974, In : Federation Proceedings. 33, 3 I, 1 p.

Research output: Contribution to journalArticle

3 Scopus citations