1966 …2019

Research output per year

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Research Output

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Article

Modification of opioid receptor activity by acid phosphatase in neuroblastoma X glioma NG108-15 hybrid cells

Louie, A. K., Zhan, J., Law, P. Y. & Loh, H. H., May 16 1988, In : Biochemical and Biophysical Research Communications. 152, 3, p. 1369-1375 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Modulating μ-opioid receptor phosphorylation switches agonist-dependent signaling as reflected in PKCε activation and dendritic spine stability

Zheng, H., Chu, J., Zhang, Y., Loh, H. H. & Law, P. Y., Apr 8 2011, In : Journal of Biological Chemistry. 286, 14, p. 12724-12733 10 p.

Research output: Contribution to journalArticle

35 Scopus citations
4 Scopus citations

Modulation of mTOR Activity by μ-Opioid Receptor is Dependent upon the Association of Receptor and FK506-Binding Protein 12

Wang, Y., Ge, Y. H., Wang, Y. X., Liu, T., Law, P-Y., Loh, H. H., Chen, H. Z. & Qiu, Y., Jul 1 2015, In : CNS Neuroscience and Therapeutics. 21, 7, p. 591-598 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Modulations of NeuroD activity contribute to the differential effects of morphine and fentanyl on dendritic spine stability

Zheng, H., Zeng, Y., Chu, J., Kam, A. Y. F., Loh, H. H. & Law, P-Y., Jun 16 2010, In : Journal of Neuroscience. 30, 24, p. 8102-8110 9 p.

Research output: Contribution to journalArticle

47 Scopus citations

Molecular basis of cellular localization of poly C binding protein 1 in neuronal cells

Berry, A. M., Flock, K. E., Loh, H. H. & Ko, J. L., Nov 3 2006, In : Biochemical and Biophysical Research Communications. 349, 4, p. 1378-1386 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Molecular basis underlying the poly C binding protein 1 as a regulator of the proximal promoter of mouse μ-opioid receptor gene

Malik, A. K., Flock, K. E., Godavarthi, C. L., Loh, H. H. & Ko, J. L., Sep 27 2006, In : Brain Research. 1112, 1, p. 33-45 13 p.

Research output: Contribution to journalArticle

13 Scopus citations

Molecular characterization of a new immunoglobulin superfamily protein with potential roles in opioid binding and cell contact

Schofield, P. R., McFarland, K. C., Hayflick, J. S., Wilcox, J. N., Cho, T. M., Roy, S., Lee, N. M., Loh, H. H. & Seeburg, P. H., Jan 1 1989, In : EMBO Journal. 8, 2, p. 489-495 7 p.

Research output: Contribution to journalArticle

93 Scopus citations

Molecular characterization of opioid receptors

Loh, H. H. & Smith, A. P., Jan 1 1990, In : Annual Review of Pharmacology and Toxicology. 30, 1, p. 123-147 25 p.

Research output: Contribution to journalArticle

180 Scopus citations

Molecular cloning of a novel protein regulated by opioid treatment of NG108-15 cells

Wick, M. J., Ann, D. K. & Loh, H. H., Aug 1995, In : Molecular Brain Research. 32, 1, p. 171-175 5 p.

Research output: Contribution to journalArticle

20 Scopus citations

Molecular mechanisms of opiate tolerance and dependence in a clonal cell line

Louie, A. K., Law, P. Y. & Loh, H. H., Jan 1 1985, In : NIDA Research Monograph Series. NO. 62, p. 117-128 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Morphine and beta-endorphin on RNA synthesis.

Lee, N. M., Loh, H. H. & Li, C. H., Jan 1 1978, In : Advances in biochemical psychopharmacology. 18, p. 278-288 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Morphine drives internal ribosome entry site-mediated hnRNP K translation in neurons through opioid receptor-dependent signaling

Lee, P. T., Chao, P. K., Ou, L. C., Chuang, J. Y., Lin, Y. C., Chen, S. C., Chang, H. F., Law, P. Y., Loh, H. H., Chao, Y. S., Su, T. P. & Yeh, S. H., Dec 1 2014, In : Nucleic acids research. 42, 21, p. 13012-13025 14 p.

Research output: Contribution to journalArticle

13 Scopus citations
11 Scopus citations

Morphine-induced μ-opioid receptor rapid desensitization is independent of receptor phosphorylation and β-arrestins

Chu, J., Zheng, H., Loh, H. H. & Law, P-Y., Sep 1 2008, In : Cellular Signalling. 20, 9, p. 1616-1624 9 p.

Research output: Contribution to journalArticle

43 Scopus citations
38 Scopus citations

Morphine induces CD4+ T cell IL-4 expression through an adenylyl cyclase mechanism independent of the protein kinase A pathway

Roy, S., Wang, J., Charboneau, R., Loh, H. H. & Barke, R. A., Nov 15 2005, In : Journal of Immunology. 175, 10, p. 6361-6367 7 p.

Research output: Contribution to journalArticle

57 Scopus citations

Morphine inhibits Fc-mediated phagocytosis through mu and delta opioid receptors

Tomassini, N., Renaud, F., Roy, S. & Loh, H. H., Feb 2004, In : Journal of Neuroimmunology. 147, 1-2, p. 131-133 3 p.

Research output: Contribution to journalArticle

24 Scopus citations

Morphine modulates adult neurogenesis and contextual memory by impeding the maturation of neural progenitors

Zhang, Y., Xu, C., Zheng, H., Loh, H. H. & Law, P. Y., Apr 2016, In : PloS one. 11, 4, e0153628.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Morphine modulates lymph node-derived T lymphocyte function: Role of caspase-3, -8, and nitric oxide

Wang, J., Charboneau, R., Balasubramanian, S., Barke, R. A., Loh, H. H. & Roy, S., Oct 22 2001, In : Journal of Leukocyte Biology. 70, 4, p. 527-536 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

Morphine modulates mouse hippocampal progenitor cell lineages by upregulating miR-181a level

Xu, C., Zhang, Y., Zheng, H., Loh, H. H. & Law, P. Y., Nov 1 2014, In : STEM CELLS. 32, 11, p. 2961-2972 12 p.

Research output: Contribution to journalArticle

24 Scopus citations

Morphine negatively regulates interferon-γ promoter activity in activated murine T cells through two distinct cyclic AMP-dependent pathways

Wang, J., Barke, R. A., Charboneau, R., Loh, H. H. & Roy, S., Sep 26 2003, In : Journal of Biological Chemistry. 278, 39, p. 37622-37631 10 p.

Research output: Contribution to journalArticle

70 Scopus citations
16 Scopus citations

Morphine regulates adult neurogenesis and contextual memory extinction via the PKCε/Prox1 pathway

Fan, W., Wang, H., Zhang, Y., Loh, H. H., Law, P. Y. & Xu, C., Oct 2018, In : Neuropharmacology. 141, p. 126-138 13 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Morphine regulates dopaminergic neuron differentiation via miR-133b

Sanchez-Simon, F. M., Zhang, X. X., Loh, H. H., Law, P-Y. & Rodriguez, R. E., Nov 1 2010, In : Molecular Pharmacology. 78, 5, p. 935-942 8 p.

Research output: Contribution to journalArticle

80 Scopus citations

Morphine self-administration in μ-opioid receptor-deficient mice

Becker, A., Grecksch, G., Brödemann, R., Kraus, J., Peters, B., Schroeder, H., Thiemann, W., Loh, H. H. & Höllt, V., Jun 24 2000, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 361, 6, p. 584-589 6 p.

Research output: Contribution to journalArticle

68 Scopus citations

Morphine tolerance, physical dependence, and synthesis of brain 5-hydroxytryptamine

Way, E. L., Loh, H. H. & Shen, F. H., Jan 1 1968, In : Science. 162, 3859, p. 1290-1292 3 p.

Research output: Contribution to journalArticle

194 Scopus citations

Mouse Brain DNA‐Dependent RNA Polymerases After Chronic Morphine Treatment

Stokes, K. B., Lee, N. M. & Loh, H. H., May 1980, In : Journal of Neurochemistry. 34, 5, p. 1058-1064 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Mouse κ-opioid receptor mRNA differential transport in neurons

Bi, J., Hu, X., Loh, H. H. & Wei, L-N., Sep 1 2003, In : Molecular Pharmacology. 64, 3, p. 594-599 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Mouse μ opioid receptor distal promoter transcriptional regulation by SOX proteins

Hwang, C. K., Wu, X., Wang, G., Kim, C. S. & Loh, H. H., Feb 7 2003, In : Journal of Biological Chemistry. 278, 6, p. 3742-3750 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Mouse μ opioid receptor gene expression. A 34-base pair cis-acting element inhibits transcription of the μ opioid receptor gene from the distal promoter

Choe, C. Y., Im, H. J., Ko, J. L. & Loh, H. H., Dec 25 1998, In : Journal of Biological Chemistry. 273, 52, p. 34926-34932 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

Mu and delta receptors mediate morphine effects on phagocytosis by murine peritoneal macrophages

Tomassini, N., Renaud, F. L., Roy, S. & Loh, H. H., Mar 2003, In : Journal of Neuroimmunology. 136, 1-2, p. 9-16 8 p.

Research output: Contribution to journalArticle

30 Scopus citations
40 Scopus citations

Multiple molecular forms of stereospecific opiate binding

Smith, A. P. & Loh, H. H., Dec 1 1979, In : Molecular Pharmacology. 16, 3, p. 757-766 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Mu-opioid receptor is associated with phosphatase activity

Roy, S., Lee, N. M. & Loh, H. H., Oct 30 1986, In : Biochemical and Biophysical Research Communications. 140, 2, p. 660-665 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

MU-opioid receptor-knockout mice: Role of μ-opioid receptor in morphine mediated immune functions

Roy, S., Barke, R. A. & Loh, H. H., Oct 30 1998, In : Molecular Brain Research. 61, 1-2, p. 190-194 5 p.

Research output: Contribution to journalArticle

125 Scopus citations
93 Scopus citations

Mutational analysis of the structure and function of opioid receptors

Law, P. Y., Wong, Y. H. & Loh, H. H., Dec 1 1999, In : Biopolymers - Peptide Science Section. 51, 6, p. 440-455 16 p.

Research output: Contribution to journalArticle

57 Scopus citations

Mutation of a conserved serine in TM4 of opioid receptors confers full agonistic properties to classical antagonists

Claude, P. A., Wotta, D. R., Zhang, X. H., Prather, P. L., McGinn, T. M., Erickson, L. J., Loh, H. H. & Law, P. Y., Jun 27 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 12, p. 5715-5719 5 p.

Research output: Contribution to journalArticle

62 Scopus citations

Naloxone can act as an analgesic agent without measurable chronic side effects in mice with a mutant mu-opioid receptor expressed in different sites of pain pathway

Chou, S. H., Kao, J. H., Tao, P. L., Law, P. Y. & Loh, H. H., Aug 1 2012, In : Synapse. 66, 8, p. 694-704 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Naltrexone Facilitates Learning and Delays Extinction by Increasing AMPA Receptor Phosphorylation and Membrane Insertion

Kibaly, C., Kam, A. Y. F., Loh, H. H. & Law, P. Y., Jun 1 2016, In : Biological psychiatry. 79, 11, p. 906-916 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Narcotic binding to membrane acidic lipids

Loh, H. H., Cho, T. M., Cho, J. S. & Way, E. L., Jan 1 1979, In : Progress in clinical and biological research. VOL. 27, p. 27-49 23 p.

Research output: Contribution to journalArticle

1 Scopus citations

Narcotic tolerance and dependence and serotonin turnover

Hitzemann, R. J., Ho, I. K., Loh, H. H., Cheney, D. L. & Costa, E., Jan 1 1972, In : Science. 178, 4061, p. 645-647 3 p.

Research output: Contribution to journalArticle

4 Scopus citations

Netrin-1 signaling regulates de novo protein synthesis of κ opioid receptor by facilitating polysomal partition of its mRNA

Tsai, N. P., Bi, J., Loh, H. H. & Wei, L-N., Sep 20 2006, In : Journal of Neuroscience. 26, 38, p. 9743-9749 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

Neurite outgrowth is dependent on the association of c-Src and lipid rafts

Zhao, H., Cao, X., Wu, G., Loh, H. H. & Law, P. Y., Dec 1 2009, In : Neurochemical Research. 34, 12, p. 2197-2205 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Neuroanatomical and chemical correlates of naloxone-precipitated withdrawal.

Way, E. L., Loh, H. H., Ho, I. K., Iwamoto, E. T. & Wei, E., Dec 1 1973, In : Advances in biochemical psychopharmacology. 8, 0, p. 455-469 15 p.

Research output: Contribution to journalArticle

15 Scopus citations

Neuroanatomical correlates of morphine dependence

Wei, E., Loh, H. H. & Way, E. L., Jan 1 1972, In : Science. 177, 4049, p. 616-617 2 p.

Research output: Contribution to journalArticle

76 Scopus citations

Neuroanatomical correlates of wet shake behavior in the rat

Wei, E., Loh, H. H. & Leong Way, E., 1973, In : Life Sciences. 12, 11 PART 2, p. 489-496 8 p.

Research output: Contribution to journalArticle

37 Scopus citations
51 Scopus citations
2 Scopus citations