Projects per year
Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
- 5 Similar Profiles
Integrases
Medicine & Life Sciences
DNA
Medicine & Life Sciences
Rous sarcoma virus
Medicine & Life Sciences
Single-Stranded DNA
Medicine & Life Sciences
Proteins
Medicine & Life Sciences
Crystal structure
Chemical Compounds
Catalytic Domain
Medicine & Life Sciences
Viruses
Chemical Compounds
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2008 2024
APOBEC MUTAGENESIS IN BREAST CANCER
Harris, R., Aihara, H., Harki, D. A., Largaespada, D. A. & Yee, D.
NIH NATIONAL CANCER INSTITUTE (NCI)
8/9/19 → 7/31/24
Project: Research project
Mutagenesis
Breast Neoplasms
Discovery and development of novel anti-HCMV agents targeting the UL89 terminase protein
Geraghty, R. J., Aihara, H., Wang, Z. & Xie, J.
NIH Nat'l Inst of Allergy & Infect Dis
1/25/19 → 12/31/23
Project: Research project
Proteins
terminase
Targeting eIF4A1-dependent HK2 translation axis for prevention of castration-resistant prostate cancer
Deng, Y., Aihara, H., Bhat, M. S., Murugan, P. & Zhang, L.
NIH NATIONAL CANCER INSTITUTE (NCI)
12/1/18 → 11/30/23
Project: Research project
Castration
Prostatic Neoplasms
Development and characterization of peptidomimetic small molecule activators of peptidase neurolysin for stroke therapy.
9/15/18 → 8/31/23
Project: Research project
neurolysin
Peptidomimetics
Peptide Hydrolases
Stroke
Therapeutics
Structural studies of DNA-processing enzymes
NIH NIGMS NATL INST OF GENERAL
7/1/16 → 6/30/21
Project: Research project
DNA
Enzymes
Research Output 1996 2019
Cyanuric acid hydrolase reveal conformational flexibility and asymmetry important for catalysis
Shi, K., Cho, S., Aukema, K. G., Lee, T., Bera, A. K., Seffernick, J. L., Wackett, L. P. & Aihara, H., Jun 2019, In : PloS one. 14, 6, e0216979.Research output: Contribution to journal › Article
Open Access
Hydrolases
hydrolases
Catalysis
catalytic activity
acids
4
Citations
(Scopus)
Determinants of Oligonucleotide Selectivity of APOBEC3B
Wagner, J. R., Demir, Ö., Carpenter, M. A., Aihara, H., Harki, D. A., Harris, R. & Amaro, R. E., May 28 2019, In : Journal of Chemical Information and Modeling. 59, 5, p. 2264-2273 10 p.Research output: Contribution to journal › Article
Oligonucleotides
Binding sites
DNA
Binding Sites
determinants
3
Citations
(Scopus)
Hybridization of TEDOR and NCX MAS solid-state NMR experiments for simultaneous acquisition of heteronuclear correlation spectra and distance measurements
Tata, G., Wang, S., Lee, J., Aihara, H. & Veglia, G., Apr 15 2019, In : Journal of Biomolecular Nmr. 73, 3-4, p. 141-153 13 p.Research output: Contribution to journal › Article
Magic angle spinning
Distance measurement
Membrane Proteins
Nuclear magnetic resonance
Biopolymers
2
Citations
(Scopus)
Inhibiting APOBEC3 Activity with Single-Stranded DNA Containing 2′-Deoxyzebularine Analogues
Kvach, M. V., Barzak, F. M., Harjes, S., Schares, H. A. M., Jameson, G. B., Ayoub, A. M., Moorthy, R., Aihara, H., Harris, R. S., Filichev, V. V., Harki, D. A. & Harjes, E., Feb 5 2019, In : Biochemistry. 58, 5, p. 391-400 10 p.Research output: Contribution to journal › Article
Open Access
Single-Stranded DNA
Cytidine
Mutagenesis
Calorimetry
Fluorescence Polarization
1
Citation
(Scopus)
Insight into subtilisin E-S7 cleavage pattern based on crystal structure and hydrolysates peptide analysis
Tang, H., Zhang, J., Shi, K., Aihara, H. & Du, G., May 7 2019, In : Biochemical and Biophysical Research Communications. 512, 3, p. 623-628 6 p.Research output: Contribution to journal › Article
ethyl-2-methylthio-4-methyl-5-pyrimidine carboxylate
Subtilisins
Crystal structure
Peptides
Protein Engineering