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Research Output 1972 2019

1995
7 Citations (Scopus)

Genetic approaches to pathogenesis of neurodegenerative diseases

Orr, H. T. & Clark, H. B., Jan 1 1995, In : Laboratory Investigation. 73, 2, p. 161-171 11 p.

Research output: Contribution to journalReview article

Animal Disease Models
Nerve Degeneration
Brain Diseases
Molecular Cloning
Neurodegenerative Diseases
24 Citations (Scopus)

HLA‐G Transgenic Mice: A Model for Studying Expression and Function at the Maternal/Fetal Interface

SCHMIDT, CYNTHIA. M. & Orr, H. T., Jan 1 1995, In : Immunological Reviews. 147, 1, p. 53-65 13 p.

Research output: Contribution to journalArticle

HLA-G Antigens
Transgenic Mice
Mothers
Trophoblasts
Thymus Gland
264 Citations (Scopus)

Homozygotes for CDKN2 (p16) germline mutation in Dutch familial melanoma kindreds

Chong, S. S., McCall, A. E., Cota, J., Subramony, S. H., Orr, H. T., Hughes, M. R. & Zoghbi, H. Y., Jan 1 1995, In : Nature Genetics. 10, 3, p. 351-353 3 p.

Research output: Contribution to journalArticle

Germ-Line Mutation
Homozygote
Melanoma
Dysplastic Nevus Syndrome
p16 Genes
61 Citations (Scopus)

In Vivo Viability of Postmitotic Purkinje Neurons Requires pRb Family Member Function

Feddersen, R. M., Clark, H. B., Yunis, W. S. & Orr, H. T., Jan 1 1995, In : Molecular and Cellular Neuroscience. 6, 2, p. 153-167 15 p.

Research output: Contribution to journalArticle

Purkinje Cells
Transgenic Mice
Retinoblastoma Genes
DNA Fragmentation
Cell Division
51 Citations (Scopus)

Refined localization of the cerebral cavernous malformation gene (CCM1) to a 4-cM interval of chromosome 7q contained in a well-defined YAC contig

Johnson, E. W., Lyer, L. M., Rich, S. S., Orr, H. T., Gil-Nagel, A., Kurth, J. H., Zabramski, J. M., Marchuk, D. A., Weissenbach, J., Clericuzio, C. L., Davis, L. E., Hart, B. L., Gusella, J. F., Kosofsky, B. E., Louis, D. N., Morrison, L. A., Green, E. D. & Weber, J. L., Nov 1 1995, In : Genome Research. 5, 4, p. 368-380 13 p.

Research output: Contribution to journalArticle

Central Nervous System Cavernous Hemangioma
Chromosomes
Hispanic Americans
Genes
Haplotypes
464 Citations (Scopus)

SCA1 transgenic mice: A model for neurodegeneration caused by an expanded CAG trinucleotide repeat

Burright, E. N., Clark, H. B., Servadio, A., Matilla, T., Feddersen, R. M., Yunis, W. S., Duvick, L. A., Zoghbi, H. Y. & Orr, H. T., Sep 22 1995, In : Cell. 82, 6, p. 937-948 12 p.

Research output: Contribution to journalArticle

Trinucleotide Repeat Expansion
Spinocerebellar Ataxias
Trinucleotide Repeats
Transgenic Mice
Purkinje Cells
76 Citations (Scopus)

Spinocerebellar ataxia type 1

Zoghbi, H. Y. & Orr, H. T., Jan 1 1995, In : Seminars in Cell Biology. 6, 1, p. 29-35 7 p.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Alleles
Chromosomes
Dysarthria
Chromosomes, Human, Pair 6
102 Citations (Scopus)

Spinocerebellar ataxia type 1 and Machado-Joseph disease: Incidence of CAG expansions among adult-onset ataxia patients from 311 families with dominant, recessive, or sporadic ataxia

Ranum, L. P. W., Lundgren, J. K., Schut, L. J., Ahrens, M. J., Perlman, S., Aita, J., Bird, T. D., Gomez, C. & Orr, H. T., Jan 1 1995, In : American Journal of Human Genetics. 57, 3, p. 603-608 6 p.

Research output: Contribution to journalArticle

Machado-Joseph Disease
Spinocerebellar Ataxias
Ataxia
Trinucleotide Repeat Expansion
Incidence
17 Citations (Scopus)

Temporal and spatial expression of HLA-G messenger RNA in extraembryonic tissues of transgenic mice

Schmidt, C. M., Hua Lin Chen, L. C., Chiu, I., Ehlenfeldt, R. G., Hunt, J. S. & Orr, H. T., Jan 1 1995, In : Journal of Immunology. 155, 2, p. 619-629 11 p.

Research output: Contribution to journalArticle

HLA-G Antigens
Transgenic Mice
Messenger RNA
Trophoblasts
Transgenes
1994
277 Citations (Scopus)

Identification and characterization of the gene causing type 1 spinocerebellar ataxia

Banfi, S., Servadio, A., Chung, M. Y., Kwiatkowski, T. J., McCall, A. E., Duvick, L. A., Shen, Y., Roth, E. J., Orr, H. T. & Zoghbi, H. Y., Jan 1 1994, In : Nature Genetics. 7, 4, p. 513-520 8 p.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Exons
Genes
Trinucleotide Repeats
5' Untranslated Regions
151 Citations (Scopus)

Molecular and clinical correlations in spinocerebellar ataxia type I: Evidence for familial effects on the age at onset

Ranum, L. P. W., Chung, M. Y., Banfi, S., Bryer, A., Schut, L. J., Ramesar, R., Duvick, L. A., McCall, A., Subramony, S. H., Goldfarb, L., Gomez, C., Sandkuijl, L. A., Orr, H. T. & Zoghbi, H. Y., Aug 11 1994, In : American Journal of Human Genetics. 55, 2, p. 244-252 9 p.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Age of Onset
Alleles
Genes
Trinucleotide Repeats
79 Citations (Scopus)

Report of the second international workshop on human chromosome 6

Volz, A., Boyle, J. M., Cann, H. M., Cottingham, R. W., Orr, H. T. & Ziegler, A., May 15 1994, In : Genomics. 21, 2, p. 464-472 9 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 6
Human Chromosomes
Education
276 Citations (Scopus)

Spinocerebellar ataxia type 5 in a family descended from the grandparents of President Lincoln maps to chromosome 11

Ranum, L. P. W., Schut, L. J., Lundgren, J. K., Orr, H. T. & Livingston, D. M., Jan 1 1994, In : Nature Genetics. 8, 3, p. 280-284 5 p.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Chromosomes, Human, Pair 11
Ataxia
Cerebellar Ataxia
Chromosomes
81 Citations (Scopus)

The apolipoprotein E/CI/CII gene cluster and late-onset Alzheimer disease

Yu, C. E., Payami, H., Olson, J. M., Boehnke, M., Wijsman, E. M., Orr, H. T., Kukull, W. A., Goddard, K. A. B., Nemens, E., White, J. A., Alonso, M. E., Taylor, T. D., Ball, M. J., Kaye, J., Morris, J., Chui, H., Sadovnick, A. D., Martin, G. M., Larson, E. B., Heston, L. L. & 2 others, Bird, T. D. & Schellenberg, G. D., Mar 31 1994, In : American Journal of Human Genetics. 54, 4, p. 631-642 12 p.

Research output: Contribution to journalArticle

Phentolamine
Apolipoproteins E
Multigene Family
Alzheimer Disease
Gene Frequency
9 Citations (Scopus)

Unstable trinucleotide repeats and the diagnosis of neurodegenerative disease

Orr, H. T., Jan 1 1994, In : Human Pathology. 25, 6, p. 598-601 4 p.

Research output: Contribution to journalArticle

Trinucleotide Repeats
Neurodegenerative Diseases
Genetic Anticipation
Mutation
DNA
1993
20 Citations (Scopus)

Cellular distribution of HLA-G mRNA in transgenic mouse placentas

Yelavarthi, K. K., Schmidt, C. M., Ehlenfeldt, R. G., Orr, H. T. & Hunt, J. S., Oct 1 1993, In : Journal of Immunology. 151, 7, p. 3638-3645 8 p.

Research output: Contribution to journalArticle

HLA-G Antigens
Placenta
Transgenic Mice
Messenger RNA
MHC Class I Genes
57 Citations (Scopus)

Chromosome 14 and late-onset familial Alzheimer disease (FAD)

Schellenberg, G. D., Payami, H., Wijsman, E. M., Orr, H. T., Goddard, K. A. B., Anderson, L., Nemens, E., White, J. A., Alonso, M. E., Ball, M. J., Kaye, J., Morris, J. C., Chui, H., Sadovnick, A. D., Heston, L. L., Martin, G. M. & Bird, T. D., Jan 1 1993, In : American Journal of Human Genetics. 53, 3, p. 619-628 10 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 14
Alzheimer Disease
Age of Onset
Penetrance
Pedigree
400 Citations (Scopus)

Evidence for a mechanism predisposing to intergenerational CAG repeat instability in spinocerebellar ataxia type I

Chung, M. Y., Ranum, L. P. W., Duvick, L. A., Servadio, A., Zoghbi, H. Y. & Orr, H. T., Jan 1 1993, In : Nature Genetics. 5, 3, p. 254-258 5 p.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Alleles
Chromosomes
Trinucleotide Repeats
Neurodegenerative Diseases
1336 Citations (Scopus)

Expansion of an unstable trinucleotide CAG repeat in spinocerebellar ataxia type 1

Orr, H. T., Chung, M. Y., Banfi, S., Kwiatkowski, T. J., Servadio, A., Beaudet, A. L., McCall, A. E., Duvick, L. A., Ranum, L. P. W. & Zoghbi, H. Y., Jan 1 1993, In : Nature Genetics. 4, 3, p. 221-226 6 p.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Trinucleotide Repeats
Yeast Artificial Chromosomes
Cosmids
Inborn Genetic Diseases
62 Citations (Scopus)

Extraembryonic expression of the human MHC class I gene HLA-G in transgenic mice: Evidence for a positive regulatory region located 1 kilobase 5' to the start site of transcription

Schmidt, C. M., Ehlenfeldt, R. G., Athanasiou, M. C., Duvick, L. A., Heinrichs, H., David, C. S. & Orr, H. T., Jan 1 1993, In : Journal of Immunology. 151, 5, p. 2633-2645 13 p.

Research output: Contribution to journalArticle

HLA-G Antigens
MHC Class I Genes
Nucleic Acid Regulatory Sequences
Transcription Initiation Site
Transgenic Mice
5 Citations (Scopus)

Linkage studies in dominantly inherited ataxias.

Zoghbi, H. Y., Frontali, M., Orr, H. T., Sandkuijl, L., Cann, H., Sasaki, H., Chamberlain, S., Terrenato, L. & Rich, S. S., Jan 1 1993, In : Advances in neurology. 61, p. 133-137 5 p.

Research output: Contribution to journalReview article

Spinocerebellar Degenerations
Dominant Genes
Genetic Linkage
Ataxia
40 Citations (Scopus)

Mapping and cloning of the critical region for the spinocerebellar ataxia type 1 gene (SCA1) in a yeast artificial chromosome contig spanning 1.2 Mb

Banfi, S., Chung, M. Y., Kwiatkowski, T. J., Ranum, L. P. W., McCall, A. E., Chinault, A. C., Orr, H. T. & Zoghbi, H. Y., Jan 1 1993, In : Genomics. 18, 3, p. 627-635 9 p.

Research output: Contribution to journalArticle

Yeast Artificial Chromosomes
Spinocerebellar Ataxias
Organism Cloning
Genes
Clone Cells
74 Citations (Scopus)

Maternal/fetal interactions: The role of the MHC class I molecule HLA-G

Schmidt, C. M. & Orr, H. T., Dec 1 1993, In : Critical Reviews in Immunology. 13, 3-4, p. 207-224 18 p.

Research output: Contribution to journalReview article

Molecular Sequence Data
Embryonic and Fetal Development
HLA-G Antigens
Chorion
Histocompatibility Antigens Class I
17 Citations (Scopus)

The c-fos gene and early-onset familial Alzheimer's disease

Bonnycastle, L. L. C., Yu, C. E., Wijsman, E. M., Orr, H. T., Patterson, D., Clancy, K. P., Goddard, K. A. B., Alonso, M. E., Nemens, E., White, J. A., Heston, L. L., Martin, G. M., Bird, T. D. & Schellenberg, G. D., Sep 17 1993, In : Neuroscience Letters. 160, 1, p. 33-36 4 p.

Research output: Contribution to journalArticle

fos Genes
Alzheimer Disease
Yeast Artificial Chromosomes
Chromosomes, Human, Pair 14
Chromosomes
31 Citations (Scopus)

The gene for autosomal dominant spinocerebellar ataxia (SCA1) maps centromeric to D6S89 and shows no recombination, in nine large kindreds, with a dinucleotide repeat at the AM10 locus

Kwiatkowski, T. J., Orr, H. T., Banfi, S., McCall, A. E., Jodice, C., Persichetti, F., Novelletto, A., LeBorgne-DeMarquoy, F., Duvick, L. A., Frontali, M., Subramony, S. H., Beaudet, A. L., Terrenato, L., Zoghbi, H. Y. & Ranum, L. P. W., Jan 1 1993, In : American Journal of Human Genetics. 53, 2, p. 391-400 10 p.

Research output: Contribution to journalArticle

Dinucleotide Repeats
Spinocerebellar Ataxias
Dominant Genes
Genetic Recombination
Lod Score
1992
16 Citations (Scopus)

Autosomal dominant spinocerebellar ataxia: Locus heterogeneity in a Nebraska kindred

Ranum, L. P. W., Rich, S. S., Nance, M. A., Duvick, L. A., Aita, J. F., Orr, H. T., Anton-Johnson, S. & Schut, L. J., Jan 1 1992, In : Neurology. 42, 2, p. 344-347 4 p.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Ataxia
HLA-A Antigens
Gait Ataxia
Genetic Heterogeneity
179 Citations (Scopus)

Disrupted cerebellar cortical development and progressive degeneration of Purkinje cells in SV40 T antigen transgenic mice

Feddersen, R. M., Ehlenfeldt, R., Yunis, W. S., Clark, H. B. & Orr, H. T., Jan 1 1992, In : Neuron. 9, 5, p. 955-966 12 p.

Research output: Contribution to journalArticle

Polyomavirus Transforming Antigens
Purkinje Cells
Transgenic Mice
Transgenes
Ataxia
731 Citations (Scopus)

Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14

Schellenberg, G. D., Bird, T. D., Wijsman, E. M., Orr, H. T., Anderson, L., Nemens, E., White, J. A., Bonnycastle, L., Weber, J. L., Alonso, M. E., Potter, H., Heston, L. L. & Martin, G. M., Jan 1 1992, In : Science. 258, 5082, p. 668-671 4 p.

Research output: Contribution to journalArticle

Lod Score
Chromosomes, Human, Pair 14
Genetic Linkage
Alzheimer Disease
Penetrance
134 Citations (Scopus)

HLA and maternal-fetal recognition

Hunt, J. S. & Orr, H. T., Mar 1 1992, In : FASEB Journal. 6, 6, p. 2344-2348 5 p.

Research output: Contribution to journalArticle

Mothers
antigens
Antigens
Trophoblasts
trophoblast
46 Citations (Scopus)

HLA-J, a second inactivated class I HLA gene related to HLA-G and HLA-A: Implications for the evolution of the HLA-A-related genes

Messer, G., Zemmour, J., Orr, H. T., Parham, P., Weiss, E. H. & Girdlestone, J., Jan 1 1992, In : Journal of Immunology. 148, 12, p. 4043-4053 11 p.

Research output: Contribution to journalArticle

HLA-G Antigens
MHC Class I Genes
HLA-A Antigens
Genes
HLA-C Antigens
203 Citations (Scopus)

Linkage and mutational analysis of familial Alzheimer disease kindreds for the APP gene region

Kamino, K., Orr, H. T., Payami, H., Wijsman, E. M., Alonso, M. E., Pulst, S. M., Anderson, L., O'Dahl, S., Nemens, E., White, J. A., Sadovnick, A. D., Ball, M. J., Kaye, J., Warren, A., McInnis, M., Antonarakis, S. E., Korenberg, J. R., Sharma, V., Kukull, W., Larson, E. & 4 others, Heston, L. L., Martin, G. M., Bird, T. D. & Schellenberg, G. D., Jan 1 1992, In : American Journal of Human Genetics. 51, 5, p. 998-1014 17 p.

Research output: Contribution to journalArticle

Amyloid beta-Protein Precursor
Alzheimer Disease
Codon
Genes
Mutation
102 Citations (Scopus)

The HLA class I gene family includes at least six genes and twelve pseudogenes and gene fragments

Geraghty, D. E., Koller, B. H., Hansen, J. A. & Orr, H. T., Sep 15 1992, In : Journal of Immunology. 149, 6, p. 1934-1946 13 p.

Research output: Contribution to journalArticle

MHC Class I Genes
Pseudogenes
Genes
Cosmids
Clone Cells
1991
23 Citations (Scopus)

A physical linkage map of HLA-A, -G, -7.5p, and -F

Schmidt, C. M. & Orr, H. T., Jan 1 1991, In : Human Immunology. 31, 3, p. 180-185 6 p.

Research output: Contribution to journalArticle

HLA Antigens
MHC Class I Genes
Cell Line
Transformed Cell Line
Pseudogenes
21 Citations (Scopus)

Dinucleotide repeat polymorphism at the D6S109 locus

Ranum, L. P. W., Chung, M. Y., Duvick, L. A., Zoghbi, H. Y. & Orr, H. T., Mar 11 1991, In : Nucleic acids research. 19, 5, 1 p.

Research output: Contribution to journalComment/debate

Molecular Sequence Data
Dinucleotide Repeats
Chromosomes, Human, Pair 6
Polymerase Chain Reaction
Oligodeoxyribonucleotides
14 Citations (Scopus)

Linkage of an Alzheimer disease susceptibility locus to markers on human chromosome 21

Heston, L. L., Orr, H. T., Rich, S. S. & White, J. A., Jan 1 1991, In : American Journal of Medical Genetics. 40, 4, p. 449-453 5 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 21
Disease Susceptibility
Human Chromosomes
Alzheimer Disease
Restriction Fragment Length Polymorphisms
82 Citations (Scopus)

Localization of the autosomal dominant HLA-linked spinocerebellar ataxis (SCA1) locus, in two kindreds, within an 8-cM subregion of chromosome 6p

Ranum, L. P. W., Duvick, L. A., Rich, S. S., Schut, L. J., Litt, M. & Orr, H. T., Aug 29 1991, In : American Journal of Human Genetics. 49, 1, p. 31-41 11 p.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Chromosomes
HLA-A Antigens
Genetic Markers
Genetic Recombination
16 Citations (Scopus)
Steroid 21-Hydroxylase
Pseudogenes
HLA-B44 Antigen
Genetic Recombination
Genes
13 Citations (Scopus)

Protocol for genetic testing in Huntington disease: Three years of experience in Minnesota

Nance, M. A., LeRoy, B. S., Orr, H. T., Parker, T., Rich, S. S. & Heston, L. L., Jan 1 1991, In : American Journal of Medical Genetics. 40, 4, p. 518-522 5 p.

Research output: Contribution to journalArticle

Huntington Disease
Genetic Testing
Molecular Biology
Genetic Services
Psychology
110 Citations (Scopus)

Purkinje cell protein-2 regulatory regions and transgene expression in cerebellar compartments

Vandaele, S., Nordquist, D. T., Feddersen, R. M., Tretjakoff, I., Peterson, A. C. & Orr, H. T., Jan 1 1991, In : Genes and Development. 5, 7, p. 1136-1148 13 p.

Research output: Contribution to journalArticle

Nucleic Acid Regulatory Sequences
Purkinje Cells
Transgenes
Galactosidases
Proteins
1990
1 Citation (Scopus)

A polymorphic DNA probe, p1-10-2, from chromosome 6

Duvick, L., Rich, S. S. & Orr, H. T., May 25 1990, In : Nucleic acids research. 18, 10, 1 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 6
DNA Probes
Chromosomes
Restriction Fragment Length Polymorphisms
Chromosome
180 Citations (Scopus)

Differential expression of HLA-E, HLA-F, and HLA-G transcripts in human tissue

Wei, X. & Orr, H. T., Jan 1 1990, In : Human Immunology. 29, 2, p. 131-142 12 p.

Research output: Contribution to journalArticle

HLA-G Antigens
MHC Class I Genes
Placenta
First Pregnancy Trimester
Membranes
8 Citations (Scopus)

Frequency of the ΔPhe508 mutation and correlation with XV.2c/KM-19 haplotypes in an American population of cystic fibrosis patients: Results of a collaborative study

Highsmith, W. E., Chong, G. L., Orr, H. T., Perry, T. R., Schaid, D., Farber, R., Wagner, K., Knowles, M. R., Warwick, W. J., Silverman, L. M. & Thibodeau, S. N., Nov 23 1990, In : Clinical Chemistry. 36, 10, p. 1741-1746 6 p.

Research output: Contribution to journalArticle

Mutation Rate
Chromosomes
Cystic Fibrosis
Haplotypes
Population
313 Citations (Scopus)

Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder

St. George-Hyslop, P. H., Haines, J. L., Farrer, L. A., Polinsky, R., Van Broeckhoven, C., Goate, A., McLachlan, D. R. C., Orr, H., Bruni, A. C., Sorbi, S., Rainero, I., Foncin, J. F., Pollen, D., Cantu, J. M., Tupler, R., Voskresenskaya, N., Mayeux, R., Growdon, J., Fried, V. A., Myers, R. H. & 46 others, Nee, L., Backhovens, H., Martin, J. J., Rossor, M., Owen, M. J., Mullan, M., Percy, M. E., Karlinsky, H., Rich, S., Heston, L., Montesi, M., Mortilla, M., Nacmias, N., Gusella, J. F., Hardy, J. A., Abe, K., Amaducci, L., Bergamini, L., Bruyland, M., Cappa, S., Connor, L., De Winter, G., Drachman, D., Feldman, R. G., Fracarro, M., Franco, M. E., Frommelt, P., Gavrilova, S. I., Gei, G., Gheuens, J., Haynes, A., Henry, J., James, L., James, M. F., O'Donnell, B., Piacentini, S., Pinessi, L., Roques, P., Ruiz, C., Swearer, J., Tanzi, R. E., Vandenberghe, A., Vartanian, M., Vaula, G., Watkins, P. C. & Williamson, R., Jan 1 1990, In : Nature. 347, 6289, p. 194-197 4 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 21
Genetic Linkage
Alzheimer Disease
Confounding Factors (Epidemiology)
Pedigree
62 Citations (Scopus)

HLA-AR, an inactivated antigen-presenting locus related to HLA-A implications for the evolution of the MHC

Zemmour, J., Koller, B. H., Ennis, P. D., Geraghty, D. E., Lawlor, D. A., Orr, H. T. & Parham, P., May 1 1990, In : Journal of Immunology. 144, 9, p. 3619-3629 11 p.

Research output: Contribution to journalArticle

MHC Class I Genes
HLA-A Antigens
Alleles
Peptide T
T-Lymphocytes
39 Citations (Scopus)

HLA non-A,B,C class I genes: Their structure and expression

Heinrichs, H. & Orr, H. T., Dec 1 1990, In : Immunologic Research. 9, 4, p. 265-274 10 p.

Research output: Contribution to journalArticle

Nucleic Acid Sequence Homology
Molecular Sequence Data
MHC Class I Genes
Histocompatibility Antigens Class I
Organ Specificity
158 Citations (Scopus)

Human Leukocyte Antigen F (HLA-F): An expressed HLA gene composed of a class I coding sequence linked to a novel transcribed repetitive element

Geraghty, D. E., Wei, X., Orr, H. T. & Koller, B. H., Jan 1 1990, In : Journal of Experimental Medicine. 171, 1, p. 1-18 18 p.

Research output: Contribution to journalArticle

Nucleic Acid Sequence Homology
Molecular Sequence Data
Genetic Transcription
MHC Class I Genes
RNA Probes
13 Citations (Scopus)

Sequence of a murine cDNA, pcp-4, that encodes the homolog of the rat brain-specific antigen PEP-19

Shin-Lin, C. & Orr, H. T., Mar 11 1990, In : Nucleic Acids Research. 18, 5, p. 1304 1 p.

Research output: Contribution to journalArticle

Nerve Tissue Proteins
Nucleic Acid Sequence Homology
Molecular Sequence Data
Organ Specificity
Amino Acid Sequence
1989
89 Citations (Scopus)

Chrosomal organization of the human major histocompatibility complex class I gene family

Koller, B. H., Geraghty, D. E., DeMars, R., Duvick, L., Rich, S. S. & Orr, H. T., Jan 1 1989, In : Journal of Experimental Medicine. 169, 2, p. 469-480 12 p.

Research output: Contribution to journalArticle

MHC Class I Genes
HLA-A Antigens
Major Histocompatibility Complex
HLA-G Antigens
HLA-C Antigens
25 Citations (Scopus)

Diversity of class I HLA molecules: Functional and evolutionary interactions with T cells

Parham, P., Benjamin, R. J., Chen, B. P., Clayberger, C., Ennis, P. D., Krensky, A. M., Lawlor, D. A., Littman, D. R., Norment, A. M., Orr, H. T., Salter, R. D. & Zemmour, J., Dec 1 1989, In : Cold Spring Harbor Symposia on Quantitative Biology. 54, 1, p. 529-543 15 p.

Research output: Contribution to journalArticle

T-lymphocytes

Molecular genetics of the human leukocyte antigen complex.

Orr, H. T., Jan 1 1989, In : Immunology series. 43, p. 319-338 20 p.

Research output: Contribution to journalReview article

Pseudogenes
Chromosome Mapping
Molecular Cloning
HLA Antigens
Molecular Biology