Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Identifying symptomatic and neuroprotective strategies for cerebellar ataxia
UT Southwestern Medical Center
4/20/21 → 3/31/24
Project: Research project
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Etiology of cognitive decline in Spinocerebellar ataxia type 1
Cvetanovic, M., Araque, A. & Orr, H. T.
NIH NAT INST OF NEURO DISORDERS & STROKE
9/15/20 → 6/30/25
Project: Research project
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Label-free Optical Imaging of Atrophy in SCA1 Mouse Models
National Ataxia Foundation, Inc.
3/1/20 → 12/30/22
Project: Research project
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Cell signaling and neurodegeneration
Orr, H. T. & Walters, M. A.
NIH NAT INST OF NEURO DISORDERS & STROKE
5/1/18 → 4/30/23
Project: Research project
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Autistic-like behavior and cerebellar dysfunction in Bmal1 mutant mice ameliorated by mTORC1 inhibition
Liu, D., Perez de Nanclares Fernandez, C., Simbriger, K., Fang, K., Lorsung, E., Le, N., Amorim, I. S., Chalkiadaki, K., Pathak, S. S., Li, J., Gewirtz, J. C., Jin, V. X., Kofuji, P., Araque, A., Orr, H. T., Gkogkas, C. G. & Cao, R., 2022, (Accepted/In press) In: Molecular psychiatry.Research output: Contribution to journal › Article › peer-review
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Reduction of mutant ATXN1 rescues premature death in a conditional SCA1 mouse model
Orengo, J. P., Nitschke, L., van der Heijden, M. E., Ciaburri, N. A., Orr, H. T. & Zoghbi, H. Y., Apr 22 2022, In: JCI Insight. 7, 8, e154442.Research output: Contribution to journal › Article › peer-review
Open Access -
Stephen T. Warren, Ph.D. (1953-2021): A remembrance
Nelson, D. L., Clark, J., Garber, K., Glover, T., Hassold, T., Jin, P., Orr, H. T., Sherman, S. L., Zoghbi, H. & Warren, K. L., Jan 6 2022, In: American Journal of Human Genetics. 109, 1, p. 3-11 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Cholecystokinin 1 receptor activation restores normal mTORC1 signaling and is protective to Purkinje cells of SCA mice
Wozniak, E. A. L., Chen, Z., Paul, S., Yang, P., Figueroa, K. P., Friedrich, J., Tschumperlin, T., Berken, M., Ingram, M., Henzler, C., Pulst, S. M. & Orr, H. T., Oct 12 2021, In: Cell reports. 37, 2, 109831.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Consensus Paper: Strengths and Weaknesses of Animal Models of Spinocerebellar Ataxias and Their Clinical Implications
Cendelin, J., Cvetanovic, M., Gandelman, M., Hirai, H., Orr, H. T., Pulst, S. M., Strupp, M., Tichanek, F., Tuma, J. & Manto, M., Aug 10 2021, In: Cerebellum.Research output: Contribution to journal › Article › peer-review
1 Scopus citations