Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

  • 6 Similar Profiles
Spinocerebellar Ataxias Medicine & Life Sciences
Purkinje Cells Medicine & Life Sciences
Neurodegenerative Diseases Medicine & Life Sciences
Transgenic Mice Medicine & Life Sciences
Genes Medicine & Life Sciences
HLA-A Antigens Medicine & Life Sciences
MHC Class I Genes Medicine & Life Sciences
HLA-B Antigens Medicine & Life Sciences

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Projects 1996 2023

Spinocerebellar Ataxias
Molecular Biology
Spinocerebellar Ataxias
Cerebellar Ataxia

Research Output 1972 2018

Spinocerebellar ataxia type 1: Molecular mechanisms of neurodegeneration and preclinical studies

Pérez Ortiz, J. M. & Orr, H. T. Jan 1 2018 Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 1049, p. 135-145 11 p. (Advances in Experimental Medicine and Biology; vol. 1049)

Research output: Chapter in Book/Report/Conference proceedingChapter

Spinocerebellar Ataxias
Purkinje Cells
RNA Splicing
6 Citations

Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans

Lu, H. C. , Tan, Q. , Rousseaux, M. W. C. , Wang, W. , Kim, J. Y. , Richman, R. , Wan, Y. W. , Yeh, S. Y. , Patel, J. M. , Liu, X. , Lin, T. , Lee, Y. , Fryer, J. D. , Han, J. , Chahrour, M. , Finnell, R. H. , Lei, Y. , Zurita-Jimenez, M. E. , Ahimaz, P. , Anyane-Yeboa, K. & 17 others Van Maldergem, L., Lehalle, D., Jean-Marcais, N., Mosca-Boidron, A. L., Thevenon, J., Cousin, M. A., Bro, D. E., Lanpher, B. C., Klee, E. W., Alexander, N., Bainbridge, M. N., Orr, H. T., Sillitoe, R. V., Ljungberg, M. C., Liu, Z., Schaaf, C. P. & Zoghbi, H. Y. Mar 30 2017 In : Nature Genetics. 49, 4, p. 527-536 10 p.

Research output: Contribution to journalArticle

Middle Hypothalamus
Attention Deficit Disorder with Hyperactivity
Interpersonal Relations
2 Citations

Polyglutamine spinocerebellar ataxias-from genes to potential treatments

Paulson, H. L., Shakkottai, V. G., Clark, H. B. & Orr, H. T. Sep 19 2017 In : Nature Reviews Neuroscience. 18, 10, p. 613-626 14 p.

Research output: Contribution to journalReview article

Spinocerebellar Ataxias
Neurodegenerative Diseases
2 Citations

Visualizing and mapping the cerebellum with serial optical coherence scanner

Liu, C. J., Williams, K. E., Orr, H. T. & Akkin, T. Jan 1 2017 In : Neurophotonics. 4, 1, 011006

Research output: Contribution to journalArticle

Brain Stem
Optical Coherence Tomography
Nerve Fibers
11 Citations

Cerebellar Transcriptome Profiles of ATXN1 Transgenic Mice Reveal SCA1 Disease Progression and Protection Pathways

Ingram, M., Wozniak, E. A. L., Duvick, L., Yang, R., Bergmann, P., Carson, R., O'Callaghan, B., Zoghbi, H. Y., Henzler, C. & Orr, H. T. Mar 16 2016 In : Neuron. 89, 6, p. 1194-1207 14 p.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Purkinje Cells
Transgenic Mice
Disease Progression