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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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Molecular genetics of neurodegenerative pathogenic and protective pathways: The SCA1 perspective
Orr, H. T., Cvetanovic, M. & Walters, M. A.
NIH NAT INST OF NEURO DISORDERS & STROKE
5/1/22 → 4/30/30
Project: Research project
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Identifying symptomatic and neuroprotective strategies for cerebellar ataxia
UT Southwestern Medical Center
4/20/21 → 3/31/24
Project: Research project
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Etiology of cognitive decline in Spinocerebellar ataxia type 1
Cvetanovic, M., Araque, A. & Orr, H. T.
NIH NAT INST OF NEURO DISORDERS & STROKE
9/15/20 → 6/30/25
Project: Research project
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Label-free Optical Imaging of Atrophy in SCA1 Mouse Models
National Ataxia Foundation, Inc.
3/1/20 → 12/30/22
Project: Research project
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Decreasing mutant ATXN1 nuclear localization improves a spectrum of SCA1-like phenotypes and brain region transcriptomic profiles
Handler, H., Duvick, L. A., Mitchell, J. S., Cvetanovic, M., Reighard, M., Soles, A. R., Mather, K. B., Rainwater, O., Serres, S., Nichols-Meade, T., Coffin, S. L., You, Y., Ruis, B. L., O'Callaghan, B. L., Henzler, C., Zoghbi, H. Y. & Orr, H. T., Feb 15 2023, In: Neuron. 111, 4, p. 493-507.e6Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1
Coffin, S. L., Durham, M. A., Nitschke, L., Xhako, E., Brown, A. M., Revelli, J. P., Villavicencio Gonzalez, E., Lin, T., Handler, H., Dai, Y., Trostle, A. J., Wan, Y. W., Liu, Z., Sillitoe, R. V., Orr, H. T. & Zoghbi, H. Y., Feb 15 2023, In: Neuron. 111, 4, p. 481-492.e8Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Erratum: Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1 (Neuron (2023) 111(4) (481–492.e8), (S0896627322010704), (10.1016/j.neuron.2022.11.016))
Coffin, S. L., Durham, M. A., Nitschke, L., Xhako, E., Brown, A. M., Revelli, J. P., Villavicencio Gonzalez, E., Lin, T., Handler, H. P., Dai, Y., Trostle, A. J., Wan, Y. W., Liu, Z., Sillitoe, R. V., Orr, H. T. & Zoghbi, H. Y., Mar 15 2023, In: Neuron. 111, 6, p. 915 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Accumulation of senescence observed in spinocerebellar ataxia type 7 mouse model
Miller, W., Pruett, C. L. H., Stone, W., Eide, C., Riddle, M., Popp, C., Yousefzadeh, M., Lees, C., Seelig, D., Thompson, E., Orr, H., Niedernhofer, L. & Tolar, J., Oct 2022, In: PloS one. 17, 10 October, e0275580.Research output: Contribution to journal › Article › peer-review
Open Access -
Autistic-like behavior and cerebellar dysfunction in Bmal1 mutant mice ameliorated by mTORC1 inhibition
Liu, D., Perez de Nanclares Fernandez, C., Simbriger, K., Fang, K., Lorsung, E., Le, N., Amorim, I. S., Chalkiadaki, K., Pathak, S. S., Li, J., Gewirtz, J. C., Jin, V. X., Kofuji, P., Araque, A., Orr, H. T., Gkogkas, C. G. & Cao, R., 2022, (Accepted/In press) In: Molecular psychiatry.Research output: Contribution to journal › Article › peer-review
11 Scopus citations