Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Training Program in Translational Vision Sciences
McLoon, L. K. (PI) & Junge, H. (CoI)
NIH NEI NATIONAL EYE INSTITUTE
5/1/22 → 3/31/27
Project: Research project
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Investigation of a first-in-class Frizzled4/LRP5 agonist in retinal disease models
Junge, H. (PI)
NIH NEI NATIONAL EYE INSTITUTE
1/1/22 → 12/31/26
Project: Research project
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Pharmacological Restoration of the Blood-Retina Barrier in Murine Disease Models
Zhang, L. (PI) & Junge, H. (CoI)
JACK MCGOVERN COATS DISEASE FOUNDATION
1/31/23 → 7/30/24
Project: Research project
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CIHR stroke subcontract
Junge, H. (PI)
UNIVERSITY OF TORONTO, CANADIAN INSTITUTES OF HEALTH RESEARCH
4/1/21 → 9/4/25
Project: Research project
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Mayo / UMN Partnership in Regenerative Medicine
Bischof, J. C. (PI), Garry, D. J. (PI), Junge, H. (PI), Leung, C. T. (PI), Low, W. C. (PI), Ogle, B. M. (PI), Pomerantz, W. C. (PI), Ramachandran, S. (PI), Townsend, D. (PI), Tranquillo, R. T. (PI), Van de Moortele, P.-F. (PI), Garry, M. G. (CoI), Singh, B. N. (CoI), Talkachova, A. (CoI), Yannopoulos, D. (CoI) & LeBien, T. W. (Prior Principal Investigator)
7/1/20 → 6/30/26
Project: Research project
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C1q limits cystoid edema by maintaining basal β-catenin–dependent signaling and blood-retina barrier function
Zhang, L., Levey, J., Abedin, M., Jo, H. N., Odame, E., Howe, M., Douglas, K. L., Thoreen, E., McPherson, S. W., Roehrich, H., Seshagiri, S., Angers, S., Chen, Z. & Junge, H. J., Jan 9 2026, In: JCI Insight. 11, 1, e190227.Research output: Contribution to journal › Article › peer-review
Open Access -
The calcium pump ATP2B1/PMCA1 regulates CNS vascular development by facilitating Norrin- and WNT7A/B-induced Frizzled4 signaling
Jo, H. N., Kiffmeyer, E., Zhang, C., Zhang, L., Odame, E., Dinh, Q. C., Levey, J., Howe, M., Roux, K. J., Fischer, K. D., Chen, Z. & Junge, H. J., Jul 28 2026, In: Cell reports. 45, 7, p. 117605 1 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Wnt-dependent Frizzled clustering is required for Dishevelled phosphorylation but insufficient for β-catenin stabilization
Moldaver, S., Thibeault, P. E., Robitaille, M., Au, A., Lin, S., Macleod, G., Junge, H. J., Gammons, M. V., Yip, C. M. & Angers, S., Apr 7 2026, In: Science Signaling. 19, 932, eaec0204.Research output: Contribution to journal › Article › peer-review
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Wnt Pathway Agonism as a Therapeutic Strategy for Retinal Vascular Diseases: A Narrative Review of Evidence to Date
Angers, S., Wykoff, C. C., Antonetti, D. A., Junge, H. J., Nudleman, E., Nagiel, A., Schlottmann, P. G., D’Amico, D. J., Prenner, J., Guyer, D. R., Miller, C. G., Baker, K., Stephens, P., Henry, E., Rekers, H., Adamis, A. P. & Ng, Y. S. E., 2026, (Accepted/In press) In: Ophthalmology and Therapy.Research output: Contribution to journal › Review article › peer-review
Open Access -
C1q limits cystoid edema by maintaining basal β-catenin-dependent signaling and blood-retina barrier function
Zhang, L., Levey, J., Abedin, M., Jo, H. N., Odame, E., Howe, M., Douglas, K. L., Thoreen, E., McPherson, S. W., Roehrich, H., Seshagiri, S., Angers, S., Chen, Z. & Junge, H. J., Nov 24 2025, In: JCI Insight. 10, 22Research output: Contribution to journal › Article › peer-review
Open Access