Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research Interest Keywords
- O-GlcNAcylation
- Metabolism
- Adipocyte Biology
- Intestinal Homeostasis
- Immunology
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The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Perivascular adipose tissue development and maladaptation during HFpEF
Ruan, H.-B. (PI), O'Connell, T. D. (CoI), Gu, C. (Other Role) & Zhang, Y. (Other Role)
AMERICAN HEART ASSOCIATION, INC
7/1/24 → 6/30/26
Project: Research project
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Intestinal O-GlcNAc signaling and mucosal host defense
Ruan, H.-B. (PI)
NIH Nat'l Inst of Allergy & Infect Dis
2/23/22 → 1/31/27
Project: Research project
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Intestinal O-GlcNAc signaling and mucosal host defense
Ruan, H.-B. (PI)
NIH Nat'l Inst of Allergy & Infect Dis
9/20/21 → 2/22/22
Project: Research project
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Protein O-GlcNAcylation in Regulatory T Cell Function
Ruan, H.-B. (PI) & Farrar, M. A. (CoI)
NIH Nat'l Inst of Allergy & Infect Dis
11/23/18 → 10/31/24
Project: Research project
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O-GlcNAc signaling enables the intestinal epithelial rem
Ruan, H.-B. (PI)
NIH Nat'l Inst of Allergy & Infect Dis
5/15/18 → 4/30/20
Project: Research project
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Monogenic deficiency in murine intestinal Cdc42 leads to mucosal inflammation that induces crypt dysplasia
Zhang, D., Tang, W., Niu, H., Tse, W., Ruan, H. B., Dolznig, H., Knösel, T., Karl-Heinz, F., Themanns, M., Wang, J., Song, M., Denson, L., Kenner, L., Moriggl, R., Zheng, Y. & Han, X., Jan 2024, In: Genes and Diseases. 11, 1, p. 413-429 17 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
To die or not to die: Gasdermins in intestinal health and disease
Lin, Z., Chen, Q. & Ruan, H. B., Feb 2024, In: Seminars in Immunology. 71, 101865.Research output: Contribution to journal › Review article › peer-review
Open Access2 Scopus citations -
Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair
Jena, K. K., Mambu, J., Boehmer, D., Sposito, B., Millet, V., de Sousa Casal, J., Muendlein, H. I., Spreafico, R., Fenouil, R., Spinelli, L., Wurbel, S., Riquier, C., Galland, F., Naquet, P., Chasson, L., Elkins, M., Mitsialis, V., Ketelut-Carneiro, N., Bugda Gwilt, K. & Thiagarajah, J. R. & 11 others, , Dec 26 2024, In: Cell. 187, 26, p. 7533-7550.e23Research output: Contribution to journal › Article › peer-review
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O-GlcNAc glycosylation orchestrates fate decision and niche function of bone marrow stromal progenitors
Zhang, Z., Huang, Z., Awad, M., Elsalanty, M., Cray, J., Ball, L. E., Maynard, J. C., Burlingame, A. L., Zeng, H., Mansky, K. C. & Ruan, H. B., Mar 2 2023, In: eLife. 12Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Supraclavicular brown adipocytes originate from Tbx1+ myoprogenitors
Huang, Z., Gu, C., Zhang, Z., Arianti, R., Swaminathan, A., Tran, K., Battist, A., Kristóf, E. & Ruan, H. B., Dec 2023, In: PLoS biology. 21, 12, e3002413.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations
Datasets
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Condition_KO_NT_vs_WT_NT_UPREGULATED_EnrichGO.csv
JENA, K. K., MAMBU, J., BOEHMER, D., SPOSITO, B., MILLET, V., DE SOUSA CASAL, J., MUENDLEIN, H., SPREAFICO, R., FENOUIL, R., SPINELLI, L., WURBEL, S., RIQUIER, C., GALLAND, F., NAQUET, P., CHASSON, L., ELKINS, M., MITSIALIS, V., KETELUT-CARNEIRO, N., BUGDA GWILT, K., THIAGARAJAH, J., RUAN, H.-B., LIN, Z., LIEN, E., SHAO, F., CHOU, J., POLTORAK, A., ORDOVAS-MONTANES, J., FITZGERALD, K., SNAPPER, S., BROGGI, A., ZANONI, I., SPINELLI, L., Marseille-Luminy, C. D. D., Université, A.-M., Scientifique, C. N. D. R. & Médicale, I. N. D. L. S. E. D. L. R., Recherche Data Gouv, 2025
DOI: 10.57745/5lajj3, https://entrepot.recherche.data.gouv.fr/file.xhtml?persistentId=doi:10.57745/5LAJJ3
Dataset
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cibersort_run.log
JENA, K. K., MAMBU, J., BOEHMER, D., SPOSITO, B., MILLET, V., DE SOUSA CASAL, J., MUENDLEIN, H., SPREAFICO, R., FENOUIL, R., SPINELLI, L., WURBEL, S., RIQUIER, C., GALLAND, F., NAQUET, P., CHASSON, L., ELKINS, M., MITSIALIS, V., KETELUT-CARNEIRO, N., BUGDA GWILT, K., THIAGARAJAH, J., RUAN, H.-B., LIN, Z., LIEN, E., SHAO, F., CHOU, J., POLTORAK, A., ORDOVAS-MONTANES, J., FITZGERALD, K., SNAPPER, S., BROGGI, A., ZANONI, I., SPINELLI, L., Marseille-Luminy, C. D. D., Université, A.-M., Scientifique, C. N. D. R. & Médicale, I. N. D. L. S. E. D. L. R., Recherche Data Gouv, 2025
DOI: 10.57745/epxch4, https://entrepot.recherche.data.gouv.fr/file.xhtml?persistentId=doi:10.57745/EPXCH4
Dataset
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Condition_KO_NT_vs_WT_NT_GSEA_STAPP_REGENERATIVE_Score.pdf
JENA, K. K., MAMBU, J., BOEHMER, D., SPOSITO, B., MILLET, V., DE SOUSA CASAL, J., MUENDLEIN, H., SPREAFICO, R., FENOUIL, R., SPINELLI, L., WURBEL, S., RIQUIER, C., GALLAND, F., NAQUET, P., CHASSON, L., ELKINS, M., MITSIALIS, V., KETELUT-CARNEIRO, N., BUGDA GWILT, K., THIAGARAJAH, J., RUAN, H.-B., LIN, Z., LIEN, E., SHAO, F., CHOU, J., POLTORAK, A., ORDOVAS-MONTANES, J., FITZGERALD, K., SNAPPER, S., BROGGI, A., ZANONI, I., SPINELLI, L., Marseille-Luminy, C. D. D., Université, A.-M., Scientifique, C. N. D. R. & Médicale, I. N. D. L. S. E. D. L. R., Recherche Data Gouv, 2025
DOI: 10.57745/lmoxoa, https://entrepot.recherche.data.gouv.fr/file.xhtml?persistentId=doi:10.57745/LMOXOA
Dataset
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CIBERSORTx_Adjusted.txt
JENA, K. K., MAMBU, J., BOEHMER, D., SPOSITO, B., MILLET, V., DE SOUSA CASAL, J., MUENDLEIN, H., SPREAFICO, R., FENOUIL, R., SPINELLI, L., WURBEL, S., RIQUIER, C., GALLAND, F., NAQUET, P., CHASSON, L., ELKINS, M., MITSIALIS, V., KETELUT-CARNEIRO, N., BUGDA GWILT, K., THIAGARAJAH, J., RUAN, H.-B., LIN, Z., LIEN, E., SHAO, F., CHOU, J., POLTORAK, A., ORDOVAS-MONTANES, J., FITZGERALD, K., SNAPPER, S., BROGGI, A., ZANONI, I., SPINELLI, L., Marseille-Luminy, C. D. D., Université, A.-M., Scientifique, C. N. D. R. & Médicale, I. N. D. L. S. E. D. L. R., Recherche Data Gouv, 2025
DOI: 10.57745/6i9qr0, https://entrepot.recherche.data.gouv.fr/file.xhtml?persistentId=doi:10.57745/6I9QR0
Dataset
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CIBERSORTx_regional_cell_sampling_Log2TPM_fixed_nolog2_nocellid_AllTissues_inferred_refsample.txt
JENA, K. K., MAMBU, J., BOEHMER, D., SPOSITO, B., MILLET, V., DE SOUSA CASAL, J., MUENDLEIN, H., SPREAFICO, R., FENOUIL, R., SPINELLI, L., WURBEL, S., RIQUIER, C., GALLAND, F., NAQUET, P., CHASSON, L., ELKINS, M., MITSIALIS, V., KETELUT-CARNEIRO, N., BUGDA GWILT, K., THIAGARAJAH, J., RUAN, H.-B., LIN, Z., LIEN, E., SHAO, F., CHOU, J., POLTORAK, A., ORDOVAS-MONTANES, J., FITZGERALD, K., SNAPPER, S., BROGGI, A., ZANONI, I., SPINELLI, L., Marseille-Luminy, C. D. D., Université, A.-M., Scientifique, C. N. D. R. & Médicale, I. N. D. L. S. E. D. L. R., Recherche Data Gouv, 2025
DOI: 10.57745/xh3rof, https://entrepot.recherche.data.gouv.fr/file.xhtml?persistentId=doi:10.57745/XH3ROF
Dataset