Hai-Bin Ruan

Accepting PhD Students

20032023
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Personal profile

Research interests

  • O-GlcNAcylation
  • Metabolism
  • Adipocyte Biology
  • Intestinal Homeostasis
  • Immunology

Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

Liver Medicine & Life Sciences
Homeostasis Medicine & Life Sciences
Acetylglucosamine Medicine & Life Sciences
Adipose Tissue Medicine & Life Sciences
Glucose Medicine & Life Sciences
Insulin Resistance Medicine & Life Sciences
Melanocortins Medicine & Life Sciences
Genes Medicine & Life Sciences

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Projects 2016 2023

Regulatory T-Lymphocytes
Proteins
Enteroendocrine Cells
Cell Differentiation
Proteins
Inflammation
Gastrointestinal Microbiome
Hunger
Adipose Tissue
Neurons

Research Output 2003 2019

1 Citation (Scopus)

Bone marrow adipose tissue-derived stem cell factor mediates metabolic regulation of hematopoiesis

Zhang, Z., Huang, Z., Ong, B., Sahu, C., Zeng, H. & Ruan, H-B., Aug 31 2019, In : Haematologica. 104, 9, p. 1731-1743 13 p.

Research output: Contribution to journalArticle

Open Access
Stem Cell Factor
Hematopoiesis
Adipose Tissue
Hematopoietic Stem Cells
Bone Marrow

Cell metabolism control through o-glcnacylation of stat5: A full or empty fuel tank makes a big difference for cancer cell growth and survival

Rauth, M., Freund, P., Orlova, A., Grünert, S., Tasic, N., Han, X., Ruan, H. B., Neubauer, H. A. & Moriggl, R., Mar 1 2019, In : International journal of molecular sciences. 20, 5, 1028.

Research output: Contribution to journalReview article

Open Access
fuel tanks
Fuel tanks
Phosphorylation
tyrosine
Cell growth

Constitutive STAT5 activation regulates Paneth and Paneth-like cells to control Clostridium difficile colitis

Liu, R., Moriggl, R., Zhang, D., Li, H., Karns, R., Ruan, H. B., Niu, H., Mayhew, C., Watson, C., Bangar, H., Cha, S. W., Haslam, D., Zhang, T., Gilbert, S., Li, N., Helmrath, M., Wells, J., Denson, L. & Han, X., Jan 1 2019, In : Life Science Alliance. 2, 2, e201900296.

Research output: Contribution to journalArticle

Open Access
Paneth Cells
Clostridium difficile
Clostridium
colitis
Colitis

NAMPT overexpression alleviates alcohol-induced hepatic steatosis in mice

Xiong, X., Yu, J., Fan, R., Zhang, C., Xu, L., Sun, X., Huang, Y., Wang, Q., Ruan, H-B. & Qian, X., Feb 1 2019, In : PloS one. 14, 2, e0212523.

Research output: Contribution to journalArticle

Open Access
nicotinamide phosphoribosyltransferase
Nicotinamide Phosphoribosyltransferase
fatty liver
alcohols
Alcohols

O-GlcNAcase targets pyruvate kinase M2 to regulate tumor growth

Singh, J. P., Qian, K., Lee, J. S., Zhou, J., Han, X., Zhang, B., Ong, Q., Ni, W., Jiang, M., Ruan, H. B., Li, M. D., Zhang, K., Ding, Z., Lee, P., Singh, K., Wu, J., Herzog, R. I., Kaech, S., Wendel, H. G., Yates, J. R. & 4 others, Han, W., Sherwin, R. S., Nie, Y. & Yang, X., Jan 1 2019, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

Pyruvate Kinase
Glycolysis
Growth
Neoplasms
Glucose