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Research Output 1998 2019

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Article
2019
1 Citation (Scopus)
Amyotrophic Lateral Sclerosis
Motor Cortex
Upper Extremity
Pons
Disease Progression

Sensitivity of Volumetric Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy to Progression of Spinocerebellar Ataxia Type 1

Deelchand, D. K., Joers, J. M., Ravishankar, A., Lyu, T., Emir, U. E., Hutter, D., Gomez, C. M., Bushara, K. O., Lenglet, C., Eberly, L. E. & Oz, G., Jan 1 2019, In : Movement Disorders Clinical Practice.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Ataxia
Magnetic Resonance Spectroscopy
Magnetic Resonance Imaging
Disease Progression
2018
4 Citations (Scopus)

Antisense oligonucleotide-mediated ataxin-1 reduction prolongs survival in SCA1 mice and reveals disease-associated transcriptome profiles

Friedrich, J., Kordasiewicz, H. B., O'Callaghan, B., Handler, H. P., Wagener, C., Duvick, L., Swayze, E. E., Rainwater, O., Hofstra, B., Benneyworth, M., Nichols-Meade, T., Yang, P., Chen, Z., Ortiz, J. P., Clark, H. B., Oz, G., Larson, S., Zoghbi, H. Y., Henzler, C. & Orr, H. T., Nov 2 2018, In : JCI Insight. 3, 21

Research output: Contribution to journalArticle

Open Access
Spinocerebellar Ataxias
Antisense Oligonucleotides
Transcriptome
Neurological Models
RNA
2 Citations (Scopus)

AutoVOI: real-time automatic prescription of volume-of-interest for single voxel spectroscopy

Park, Y. W., Deelchand, D. K., Joers, J. M., Hanna, B., Berrington, A., Gillen, J. S., Kantarci, K., Soher, B. J., Barker, P. B., Park, H., Öz, G. & Lenglet, C., Nov 1 2018, In : Magnetic resonance in medicine. 80, 5, p. 1787-1798 12 p.

Research output: Contribution to journalArticle

Prescriptions
Spectrum Analysis
Atlases
Brain
Cerebrum
6 Citations (Scopus)

Improved localization, spectral quality, and repeatability with advanced MRS methodology in the clinical setting

Deelchand, D. K., Kantarci, K. & Oz, G., Mar 1 2018, In : Magnetic resonance in medicine. 79, 3, p. 1241-1250 10 p.

Research output: Contribution to journalArticle

Open Access
Magnetic Resonance Spectroscopy
Spectrum Analysis
Aminobutyrates
Water Quality
Central Nervous System Diseases
7 Citations (Scopus)

Neurochemical abnormalities in premanifest and early spinocerebellar ataxias

Joers, J. M., Deelchand, D. K., Lyu, T., Emir, U. E., Hutter, D., Gomez, C. M., Bushara, K. O., Eberly, L. E. & Oz, G., Apr 1 2018, In : Annals of Neurology. 83, 4, p. 816-829 14 p.

Research output: Contribution to journalArticle

Open Access
Spinocerebellar Ataxias
Ataxia
Magnetic Resonance Spectroscopy
Neurochemistry
Mutation
17 Citations (Scopus)
Open Access
Acetylcysteine
Glutathione
Parkinson Disease
Oxidative Stress
Pharmacokinetics
2017
9 Citations (Scopus)

Cerebral glycogen in humans following acute and recurrent hypoglycemia: Implications on a role in hypoglycemia unawareness

Oz, G., DiNuzzo, M., Kumar, A., Moheet, A., Khowaja, A., Kubisiak, K., Eberly, L. E. & Seaquist, E. R., Aug 1 2017, In : Journal of Cerebral Blood Flow and Metabolism. 37, 8, p. 2883-2893 11 p.

Research output: Contribution to journalArticle

Glycogen
Hypoglycemia
Hypoglycemic Agents
Brain
Occipital Lobe
4 Citations (Scopus)

Decreased Glutamate Levels in Patients with Amnestic Mild Cognitive Impairment: An sLASER Proton MR Spectroscopy and PiB-PET Study

Zeydan, B., Deelchand, D. K., Tosakulwong, N., Lesnick, T. G., Kantarci, O. H., Machulda, M. M., Knopman, D. S., Lowe, V. J., Jack, C. R., Petersen, R. C., Oz, G. & Kantarci, K., Nov 1 2017, In : Journal of Neuroimaging. 27, 6, p. 630-636 7 p.

Research output: Contribution to journalArticle

Open Access
Protons
Glutamic Acid
Magnetic Resonance Spectroscopy
Gyrus Cinguli
Inositol
3 Citations (Scopus)

Differential Effects of Intrauterine Growth Restriction on the Regional Neurochemical Profile of the Developing Rat Brain

Maliszewski Hall, A. M., Curtis, M. A., Tkac, I., Oz, G. & Rao, R., Jan 1 2017, In : Neurochemical Research. 42, 1, p. 133-140 8 p.

Research output: Contribution to journalArticle

Rats
Brain
Growth
Hippocampus
Taurine
4 Citations (Scopus)
Hypoglycemia
Glucose
Magnetic resonance spectroscopy
Hypothalamus
Medical problems
2 Citations (Scopus)

Measurement of Hypothalamic Glucose Under Euglycemia and Hyperglycemia by MRI at 3T

Joers, J. M., Deelchand, D. K., Kumar, A., Moheet, A., Seaquist, E., Henry, P. G. & Öz, G., Mar 1 2017, In : Journal of magnetic resonance imaging : JMRI. 45, 3, p. 681-691 11 p., doi: 10.1002/jmri.25383.

Research output: Contribution to journalArticle

Open Access
Hyperglycemia
Glucose
Hypothalamus
Magnetic Resonance Spectroscopy
Cerebrospinal Fluid
9 Citations (Scopus)

Ultra-High Field Proton MR Spectroscopy in Early-Stage Amyotrophic Lateral Sclerosis

Cheong, I., Marjanska, M., Deelchand, D. K., Eberly, L. E., Walk, D. & Oz, G., Jun 1 2017, In : Neurochemical Research. 42, 6, p. 1833-1844 12 p.

Research output: Contribution to journalArticle

Open Access
Amyotrophic Lateral Sclerosis
Inositol
Protons
Magnetic Resonance Spectroscopy
Spectroscopy
2016
12 Citations (Scopus)

Oxygen consumption deficit in Huntington disease mouse brain under metabolic stress

Lou, S., Lepak, V. C., Eberly, L. E., Roth, B., Cui, W., Zhu, X-H., Oz, G. & Dubinsky, J. M., Jan 1 2016, In : Human molecular genetics. 25, 13, p. 2813-2826 14 p.

Research output: Contribution to journalArticle

Physiological Stress
Huntington Disease
Oxygen Consumption
Brain
Dinitrophenols
42 Citations (Scopus)

Test-retest reproducibility of neurochemical profiles with short-echo, single-voxel MR spectroscopy at 3T and 7T

Terpstra, M., Cheong, I., Lyu, T., Deelchand, D. K., Emir, U. E., Bednarik, P., Eberly, L. E. & Oz, G., Oct 1 2016, In : Magnetic resonance in medicine. 76, 4, p. 1083-1091 9 p.

Research output: Contribution to journalArticle

Magnetic Resonance Spectroscopy
Gyrus Cinguli
Signal-To-Noise Ratio
Cerebellum
Protons
2015
7 Citations (Scopus)
Spinocerebellar Ataxias
Transgenes
Histology
Magnetic Resonance Spectroscopy
Gene Expression
7 Citations (Scopus)

Cerebrospinal fluid biomarkers in spinocerebellar ataxia: A pilot study

Brouillette, A. M., Oz, G. & Gomez, C. M., Jan 1 2015, In : Disease Markers. 2015, 413098.

Research output: Contribution to journalArticle

Cerebrospinal fluid
Spinocerebellar Ataxias
Biomarkers
Synucleins
Multiple System Atrophy
23 Citations (Scopus)

Feasibility and reproducibility of neurochemical profile quantification in the human hippocampus at 3T

Bednarik, P., Moheet, A., Deelchand, D. K., Emir, U. E., Eberly, L. E., Bareš, M., Seaquist, E. R. & Oz, G., Jun 1 2015, In : NMR in biomedicine. 28, 6, p. 685-693 9 p.

Research output: Contribution to journalArticle

Metabolites
Hippocampus
Neurochemistry
Creatine
Signal-To-Noise Ratio
8 Citations (Scopus)

In vivo Magnetic Resonance Spectroscopy of cerebral glycogen metabolism in animals and humans

Khowaja, A., Choi, I. Y., Seaquist, E. R. & Öz, G., Feb 1 2015, In : Metabolic Brain Disease. 30, 1, p. 255-261 7 p.

Research output: Contribution to journalArticle

Magnetic resonance spectroscopy
Glycogen
Metabolism
Animals
Magnetic Resonance Spectroscopy
22 Citations (Scopus)

In vivo neurometabolic profiling in patients with spinocerebellar ataxia types 1, 2, 3, and 7

Adanyeguh, I. M., Henry, P. G., Nguyen, T. M., Rinaldi, D., Jauffret, C., Valabregue, R., Emir, U. E., Deelchand, D. K., Brice, A., Eberly, L. E., Öz, G., Durr, A. & Mochel, F., Apr 15 2015, In : Movement Disorders. 30, 5, p. 662-670 9 p.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Pons
Creatine
Inositol
Neuroglia
32 Citations (Scopus)

Multi-center reproducibility of neurochemical profiles in the human brain at 7T

van de Bank, B. L., Emir, U. E., Boer, V. O., van Asten, J. J. A., Maas, M. C., Wijnen, J. P., Kan, H. E., Oz, G., Klomp, D. W. J. & Scheenen, T. W. J., Mar 1 2015, In : NMR in biomedicine. 28, 3, p. 306-316 11 p.

Research output: Contribution to journalArticle

Metabolites
Brain
Ethics Committees
Creatine
Gyrus Cinguli
13 Citations (Scopus)

Revisiting Glycogen Content in the Human Brain

Oz, G., DiNuzzo, M., Kumar, A., Moheet, A. & Seaquist, E. R., Dec 1 2015, In : Neurochemical Research. 40, 12, p. 2473-2481 9 p.

Research output: Contribution to journalArticle

Glycogen
Brain
Glucose
Magnetic resonance spectroscopy
Blood Glucose
37 Citations (Scopus)

Two-site reproducibility of cerebellar and brainstem neurochemical profiles with short-echo, single-voxel MRS at 3T

Deelchand, D. K., Adanyeguh, I. M., Emir, U. E., Nguyen, T. M., Valabregue, R., Henry, P-G., Mochel, F. & Oz, G., May 1 2015, In : Magnetic resonance in medicine. 73, 5, p. 1718-1725 8 p.

Research output: Contribution to journalArticle

Pons
Calibration
Brain Stem
Matrix Attachment Regions
Brain
2014
11 Citations (Scopus)
Type 1 Diabetes Mellitus
Hypoglycemia
Glutamic Acid
Brain
Control Groups
10 Citations (Scopus)
Hypoglycemia
gamma-Aminobutyric Acid
Magnetic Resonance Spectroscopy
Hypothalamus
Occipital Lobe
31 Citations (Scopus)

Mutant β-III spectrin causes mGluR1α mislocalization and functional deficits in a mouse model of spinocerebellar ataxia type 5

Armbrust, K. R., Wang, X., Hathorn, T. J., Cramer, S. W., Chen, G., Zu, T., Kangas, T., Zink, A. N., Öz, G., Ebner, T. J. & Ranum, L. P. W., Jan 1 2014, In : Journal of Neuroscience. 34, 30, p. 9891-9904 14 p.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Spectrin
Dendritic Spines
Purkinje Cells
Neurodegenerative Diseases
2013
12 Citations (Scopus)

Animal models and high field imaging and spectroscopy

Oz, G., Tkac, I. & Ugurbil, K., Sep 1 2013, In : Dialogues in Clinical Neuroscience. 15, 3, p. 263-278 16 p.

Research output: Contribution to journalArticle

Spectrum Analysis
Animal Models
Brain
Magnetic Resonance Spectroscopy
Magnetic Fields
14 Citations (Scopus)

Metabolomic analysis of cerebrospinal fluid indicates iron deficiency compromises cerebral energy metabolism in the infant monkey

Rao, R., Ennis, K., Oz, G., Lubach, G. R., Georgieff, M. K. & Coe, C. L., Mar 1 2013, In : Neurochemical Research. 38, 3, p. 573-580 8 p.

Research output: Contribution to journalArticle

Cerebrospinal fluid
Metabolomics
Energy Metabolism
Haplorhini
Cerebrospinal Fluid
75 Citations (Scopus)

N-acetylcysteine boosts brain and blood glutathione in gaucher and Parkinson diseases

Holmay, M. J., Terpstra, M., Coles, L. D., Mishra, U., Ahlskog, M., Oz, G., Cloyd, J. C. & Tuite, P. J., Jul 1 2013, In : Clinical Neuropharmacology. 36, 4, p. 103-106 4 p.

Research output: Contribution to journalArticle

Gaucher Disease
Acetylcysteine
Glutathione
Parkinson Disease
Brain
13 Citations (Scopus)

Non-invasive detection of neurochemical changes prior to overt pathology in a mouse model of spinocerebellar ataxia type 1

Emir, U. E., Clark, H. B., Vollmers, M. L., Eberly, L. E. & Oz, G., Dec 1 2013, In : Journal of Neurochemistry. 127, 5, p. 660-668 9 p.

Research output: Contribution to journalArticle

Magnetic resonance spectroscopy
Spinocerebellar Ataxias
Pathology
Magnetic Resonance Spectroscopy
Movement Disorders
17 Citations (Scopus)

Non-invasive measurement of cerebral oxygen metabolism in the mouse brain by ultra-high field 17O MR spectroscopy

Cui, W., Zhu, X-H., Vollmers, M. L., Colonna, E. T., Adriany, G., Tramm, B., Dubinsky, J. M. & Oz, G., Dec 1 2013, In : Journal of Cerebral Blood Flow and Metabolism. 33, 12, p. 1846-1849 4 p.

Research output: Contribution to journalArticle

Magnetic Resonance Spectroscopy
Oxygen
Brain
Nervous System Diseases
Intubation
2012
36 Citations (Scopus)
Glycogen
Type 1 Diabetes Mellitus
Hypoglycemia
Brain
Blood Glucose
91 Citations (Scopus)

Elevated pontine and putamenal gaba levels in mild-moderate parkinson disease detected by 7 tesla proton mrs

Emir, U. E., Tuite, P. J. & Oz, G., Jan 25 2012, In : PloS one. 7, 1, e30918.

Research output: Contribution to journalArticle

Parkinson disease
Pons
protons
Parkinson Disease
Protons
71 Citations (Scopus)
Brain
Aminobutyrates
Pons
Chemical shift
Substantia Nigra
2011
39 Citations (Scopus)

Distinct neurochemical profiles of spinocerebellar ataxias 1, 2, 6, and cerebellar multiple system atrophy

Oz, G., Iltis, I., Hutter, D., Thomas, W., Bushara, K. O. & Gomez, C. M., Jun 1 2011, In : Cerebellum. 10, 2, p. 208-217 10 p.

Research output: Contribution to journalArticle

Multiple System Atrophy
Spinocerebellar Ataxias
Ataxia
Inositol
Biomarkers
18 Citations (Scopus)

In vivo monitoring of recovery from neurodegeneration in conditional transgenic SCA1 mice

Oz, G., Vollmers, M. L., Nelson, C. D., Shanley, R. M., Eberly, L. E., Orr, H. T. & Clark, H. B., Dec 1 2011, In : Experimental Neurology. 232, 2, p. 290-298 9 p.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Inositol
Doxycycline
Taurine
Pathology
64 Citations (Scopus)
Cerebellum
Brain Stem
Brain
Artifacts
Protons
30 Citations (Scopus)

Simultaneous measurement of glucose transport and utilization in the human brain

Shestov, A. A., Emir, U. E., Kumar, A., Henry, P-G., Seaquist, E. R. & Oz, G., Nov 1 2011, In : American Journal of Physiology - Endocrinology and Metabolism. 301, 5

Research output: Contribution to journalArticle

Glucose
Brain
Radioactive Tracers
Blood-Brain Barrier
Energy Metabolism
2010
18 Citations (Scopus)

1H MR spectroscopy in Friedreich's ataxia and ataxia with oculomotor apraxia type 2

Iltis, I., Hutter, D., Bushara, K. O., Clark, H. B., Gross, M. D., Eberly, L. E., Gomez, C. M. & Oz, G., Oct 28 2010, In : Brain Research. 1358, p. 200-210 11 p.

Research output: Contribution to journalArticle

Friedreich Ataxia
Magnetic Resonance Spectroscopy
Volunteers
Gliosis
Pons
63 Citations (Scopus)

Neurochemical alterations in spinocerebellar ataxia type 1 and their correlations with clinical status

Oz, G., Hutter, D., Tkac, I., Clark, H. B., Gross, M. D., Jiang, H., Eberly, L. E., Bushara, K. O. & Gomez, C. M., Jul 15 2010, In : Movement Disorders. 25, 9, p. 1253-1261 9 p.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Inositol
Pons
Glutamic Acid
Ataxia
54 Citations (Scopus)
Spinocerebellar Ataxias
Magnetic Resonance Spectroscopy
Inositol
Transgenic Mice
Disease Progression
2009
72 Citations (Scopus)

Human brain glycogen metabolism during and after hypoglycemia

Oz, G., Kumar, A., Rao, J. P., Kodl, C. T., Chow, L. S., Eberly, L. E. & Seaquist, E. R., Sep 1 2009, In : Diabetes. 58, 9, p. 1978-1985 8 p.

Research output: Contribution to journalArticle

Glycogen
Hypoglycemia
Brain
Glucose Clamp Technique
Glucose
211 Citations (Scopus)
Signal-To-Noise Ratio
Magnetic Fields
Magnetic Resonance Spectroscopy
Radio
Brain
2007
104 Citations (Scopus)

Assessment of brain iron and neuronal integrity in patients with Parkinson's disease using novel MRI contrasts

Michaeli, S., Oz, G., Sorce, D. J., Garwood, M., Ugurbil, K., Majestic, S. & Tuite, P. J., Feb 15 2007, In : Movement Disorders. 22, 3, p. 334-340 7 p.

Research output: Contribution to journalArticle

Parkinson Disease
Iron
Magnetic Resonance Imaging
Substantia Nigra
Brain
80 Citations (Scopus)

Human brain glycogen content and metabolism: Implications on its role in brain energy metabolism

Oz, G., Seaquist, E. R., Kumar, A., Criego, A. B., Benedict, L. E., Rao, J. P., Henry, P-G., Van de Moortele, P-F. & Gruetter, R., Mar 1 2007, In : American Journal of Physiology - Endocrinology and Metabolism. 292, 3

Research output: Contribution to journalArticle

Glycogen
Metabolism
Energy Metabolism
Brain
Glucose
2006
76 Citations (Scopus)

Proton MRS of the unilateral substantia nigra in the human brain at 4 tesla: Detection of high GABA concentrations

Oz, G., Terpstra, M., Tkac, I., Aia, P., Lowary, J., Tuite, P. J. & Gruetter, R., Feb 1 2006, In : Magnetic resonance in medicine. 55, 2, p. 296-301 6 p.

Research output: Contribution to journalArticle

Substantia Nigra
gamma-Aminobutyric Acid
Protons
Brain
Parkinson Disease
2005
9 Citations (Scopus)

A localization method for the measurement of fast relaxing 13C NMR signals in humans at high magnetic fields

Oz, G., Henry, P-G., Tkac, I. & Gruetter, R., Jan 1 2005, In : Applied Magnetic Resonance. 29, 1, p. 159-169 11 p.

Research output: Contribution to journalArticle

nuclear magnetic resonance
magnetic fields
glycogens
muscles
scanners
69 Citations (Scopus)

Assessment of adrenoleukodystrophy lesions by high field MRS in non-sedated pediatric patients

Öz, G., Tkáč, I., Charnas, L. R., Choi, I. Y., Bjoraker, K. J., Shapiro, E. G. & Gruetter, R., Feb 8 2005, In : Neurology. 64, 3, p. 434-441 8 p.

Research output: Contribution to journalArticle

Adrenoleukodystrophy
Magnetic Resonance Spectroscopy
Pediatrics
Cell Transplantation
Creatine
2004
165 Citations (Scopus)

Neuroglial metabolism in the awake rat brain: CO2 fixation increases with brain activity

Oz, G., Berkich, D. A., Henry, P-G., Xu, Y., LaNoue, K., Hutson, S. M. & Gruetter, R., Dec 15 2004, In : Journal of Neuroscience. 24, 50, p. 11273-11279 7 p.

Research output: Contribution to journalArticle

Neuroglia
Glutamine
Brain
Glutamic Acid
Activity Cycles
33 Citations (Scopus)

Whole-brain glutamate metabolism evaluated by steady-state kinetics using a double-isotope procedure: Effects of gabapentin

Xu, Y., Oz, G., LaNoue, K. F., Keiger, C. J., Berkich, D. A., Gruetter, R. & Hutson, S. H., Sep 1 2004, In : Journal of Neurochemistry. 90, 5, p. 1104-1116 13 p.

Research output: Contribution to journalArticle

Enzyme kinetics
Metabolism
Isotopes
Glutamine
Glutamic Acid