1993 …2022

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2020

Intrinsically disordered HAX-1 regulates Ca2+ cycling by interacting with lipid membranes and the phospholamban cytoplasmic region

Larsen, E. K., Weber, D. K., Wang, S., Gopinath, T., Blackwell, D. J., Dalton, M. P., Robia, S. L., Gao, J. & Veglia, G., Jan 1 2020, In : Biochimica et Biophysica Acta - Biomembranes. 1862, 1, 183034.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Multi-receiver solid-state NMR using polarization optimized experiments (POE) at ultrafast magic angle spinning

Gopinath, T., Weber, D. K. & Veglia, G., May 1 2020, In : Journal of biomolecular NMR. 74, 4-5, p. 267-285 19 p.

Research output: Contribution to journalArticle

Nanosecond-Timescale Dynamics and Conformational Heterogeneity in Human GCK Regulation and Disease

Sternisha, S. M., Whittington, A. C., Martinez Fiesco, J. A., Porter, C., McCray, M. M., Logan, T., Olivieri, C., Veglia, G., Steinbach, P. J. & Miller, B. G., Mar 10 2020, In : Biophysical journal. 118, 5, p. 1109-1118 10 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2019

An intramembrane sensory circuit monitors sortase A-mediated processing of streptococcal adhesins

Hall, J. W., Lima, B. P., Herbomel, G. G., Gopinath, T., McDonald, L. A., Shyne, M. T., Lee, J. K., Kreth, J., Ross, K. F., Veglia, G. & Herzberg, M. C., May 7 2019, In : Science signaling. 12, 580, eaas9941.

Research output: Contribution to journalArticle

1 Scopus citations

Cushing’s syndrome driver mutation disrupts protein kinase A allosteric network, altering both regulation and substrate specificity

Walker, C., Wang, Y., Olivieri, C., Karamafrooz, A., Casby, J., Bathon, K., Calebiro, D., Gao, J., Bernlohr, D. A., Taylor, S. S. & Veglia, G., Aug 28 2019, In : Science advances. 5, 8, eaaw9298.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Dynamic allostery-based molecular workings of kinase:peptide complexes

Ahuja, L. G., Aoto, P. C., Kornev, A. P., Veglia, G. & Taylor, S. S., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 30, p. 15052-15061 10 p.

Research output: Contribution to journalArticle

Open Access

Globally correlated conformational entropy underlies positive and negative cooperativity in a kinase’s enzymatic cycle

Wang, Y., V.S, M., Kim, J., Li, G., Ahuja, L. G., Aoto, P., Taylor, S. S. & Veglia, G., Dec 1 2019, In : Nature communications. 10, 1, 799.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
4 Scopus citations

Improving the quality of oriented membrane protein spectra using heat-compensated separated local field experiments

Wang, S., Gopinath, T. & Veglia, G., Nov 1 2019, In : Journal of biomolecular NMR. 73, 10-11, p. 617-624 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Structure and Function of Tryptophan-Tyrosine Dyads in Biomimetic β Hairpins

McCaslin, T. G., Pagba, C. V., Chi, S. H., Hwang, H. J., Gumbart, J. C., Perry, J. W., Olivieri, C., Porcelli, F., Veglia, G., Guo, Z., McDaniel, M. & Barry, B. A., Apr 4 2019, In : Journal of Physical Chemistry B. 123, 13, p. 2780-2791 12 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
Open Access
2 Scopus citations

Triply compensated RF pulses in high-resolution NMR spectroscopy

Subrahmanian, M. V., Olivieri, C. & Veglia, G., Jan 1 2019, In : eMagRes. 8, 4, p. 353-362 10 p.

Research output: Contribution to journalArticle

Zooming in on protons: Neutron structure of protein kinase A trapped in a product complex

Gerlits, O., Weiss, K. L., Blakeley, M. P., Veglia, G., Taylor, S. S. & Kovalevsky, A., Jan 1 2019, In : Science advances. 5, 3, eaav0482.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations
2018

ALARM NMR for HTS triage and chemical probe validation

Dahlin, J. L., Cuellar, M., Singh, G., Nelson, K. M., Strasser, J., Rappe, T., Xia, Y., Veglia, G. & Walters, M. A., Mar 1 2018, In : Current protocols in chemical biology. 10, 1, p. 91-117 27 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
Open Access
10 Scopus citations

Clearance kinetics of the VGF-derived neuropeptide TLQP-21

Guo, Z. K., Sahu, B. S., He, R., Finan, B., Cero, C., Verardi, R., Razzoli, M., Veglia, G., Di Marchi, R. D., Miles, J. M. & Bartolomucci, A., Oct 2018, In : Neuropeptides. 71, p. 97-103 7 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Conformational Landscape of the PRKACA-DNAJB1 Chimeric Kinase, the Driver for Fibrolamellar Hepatocellular Carcinoma

Tomasini, M. D., Wang, Y., Karamafrooz, A., Li, G., Beuming, T., Gao, J., Taylor, S. S., Veglia, G. & Simon, S. M., Dec 1 2018, In : Scientific reports. 8, 1, 720.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Design and characterization of chionodracine-derived antimicrobial peptides with enhanced activity against drug-resistant human pathogens

Olivieri, C., Bugli, F., Menchinelli, G., Veglia, G., Buonocore, F., Scapigliati, G., Stocchi, V., Ceccacci, F., Papi, M., Sanguinetti, M. & Porcelli, F., Jan 1 2018, In : RSC Advances. 8, 72, p. 41331-41346 16 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Effects of the Arg9Cys and Arg25Cys mutations on phospholamban's conformational equilibrium in membrane bilayers

Nelson, S. E. D., Ha, K. N., Gopinath, T., Exline, M. H., Mascioni, A., Thomas, D. D. & Veglia, G., Jun 2018, In : Biochimica et Biophysica Acta - Biomembranes. 1860, 6, p. 1335-1341 7 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Simultaneous detection of intra-and inter-molecular paramagnetic relaxation enhancements in protein complexes

Olivieri, C., Subrahmanian, M. V., Xia, Y., Kim, J., Porcelli, F. & Veglia, G., Jan 1 2018, In : Journal of biomolecular NMR. 70, 3, p. 133-140 8 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2017
Open Access
7 Scopus citations

A dynamic hydrophobic core orchestrates allostery in protein kinases

Kim, J., Ahuja, L. G., Chao, F. A., Xia, Y., McClendon, C. L., Kornev, A. P., Taylor, S. S. & Veglia, G., Apr 2017, In : Science Advances. 3, 4, e1600663.

Research output: Contribution to journalArticle

Open Access
38 Scopus citations

Corrigendum: Structural basis of synaptic vesicle assembly promoted by α-synuclein

Fusco, G., Pape, T., Stephens, A. D., Mahou, P., Costa, A. R., Kaminski, C. F., Schierle, G. S. K., Vendruscolo, M., Veglia, G., Dobson, C. M. & De Simone, A., May 11 2017, In : Nature communications. 8, 1 p.

Research output: Contribution to journalArticle

Open Access

Enhancing the sensitivity of multidimensional NMR experiments by using triply-compensated π pulses

Xia, Y., Rossi, P., Subrahmanian, M. V., Huang, C., Saleh, T., Olivieri, C., Kalodimos, C. G. & Veglia, G., Dec 1 2017, In : Journal of biomolecular NMR. 69, 4, p. 237-243 7 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Mutation of a kinase allosteric node uncouples dynamics linked to phosphotransfer

Ahuja, L. G., Kornev, A. P., Mcclendon, C. L., Veglia, G. & Taylor, S. S., Feb 7 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 6, p. E931-E940

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

Optimization of 1H decoupling eliminates sideband artifacts in 3D TROSY-based triple resonance experiments

Xia, Y., Rossi, P., Tonelli, M., Huang, C., Kalodimos, C. G. & Veglia, G., Sep 1 2017, In : Journal of biomolecular NMR. 69, 1, p. 45-52 8 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
11 Scopus citations

Solution and Solid-State Nuclear Magnetic Resonance Structural Investigations of the Antimicrobial Designer Peptide GL13K in Membranes

Harmouche, N., Aisenbrey, C., Porcelli, F., Xia, Y., Nelson, S. E., Chen, X., Raya, J., Vermeer, L., Aparicio, C., Veglia, G., Gorr, S-U. & Bechinger, B., Aug 15 2017, In : Biochemistry. 56, 32, p. 4269-4278 10 p.

Research output: Contribution to journalArticle

10 Scopus citations
2016

15N and 13C- SOFAST-HMQC editing enhances 3D-NOESY sensitivity in highly deuterated, selectively [1H,13C]-labeled proteins

Rossi, P., Xia, Y., Khanra, N., Veglia, G. & Kalodimos, C. G., Dec 1 2016, In : Journal of biomolecular NMR. 66, 4, p. 259-271 13 p.

Research output: Contribution to journalArticle

14 Scopus citations

Accurate Determination of Conformational Transitions in Oligomeric Membrane Proteins

Sanz-Hernández, M., Vostrikov, V. V., Veglia, G. & De Simone, A., Mar 15 2016, In : Scientific reports. 6, 23063.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Ca2+ ATPase Conformational Transitions in Lipid Bilayers Mapped by Site-directed Ethylation and Solid-State NMR

Vostrikov, V. V., Gustavsson, M., Tata, G., Mullen, D., Dicke, A. A., Truong, V. & Veglia, G., Feb 19 2016, In : ACS Chemical Biology. 11, 2, p. 329-334 6 p.

Research output: Contribution to journalArticle

4 Scopus citations
14 Scopus citations

NMR structure and conformational dynamics of AtPDFL2.1, a defensin-like peptide from Arabidopsis thaliana

Omidvar, R., Xia, Y., Porcelli, F., Bohlmann, H. & Veglia, G., Dec 1 2016, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1864, 12, p. 1739-1747 9 p.

Research output: Contribution to journalArticle

5 Scopus citations
6 Scopus citations

Probing Residue-Specific Water-Protein Interactions in Oriented Lipid Membranes via Solid-State NMR Spectroscopy

Dicke, A., Gopinath, T., Wang, Y. & Veglia, G., Oct 27 2016, In : Journal of Physical Chemistry B. 120, 42, p. 10959-10968 10 p.

Research output: Contribution to journalArticle

2 Scopus citations
Open Access
7 Scopus citations

Structural basis of synaptic vesicle assembly promoted by α-synuclein

Fusco, G., Pape, T., Stephens, A. D., Mahou, P., Costa, A. R., Kaminski, C. F., Kaminski Schierle, G. S., Vendruscolo, M., Veglia, G., Dobson, C. M. & De Simone, A., Sep 19 2016, In : Nature communications. 7, 12563.

Research output: Contribution to journalArticle

Open Access
69 Scopus citations

Structural Ensembles of Membrane-bound α-Synuclein Reveal the Molecular Determinants of Synaptic Vesicle Affinity

Fusco, G., De Simone, A., Arosio, P., Vendruscolo, M., Veglia, G. & Dobson, C. M., Jun 8 2016, In : Scientific reports. 6, 27125.

Research output: Contribution to journalArticle

Open Access
35 Scopus citations

Uncoupling Catalytic and Binding Functions in the Cyclic AMP-Dependent Protein Kinase A

Kim, J., Li, G., Walters, M. A., Taylor, S. S. & Veglia, G., Mar 1 2016, In : Structure. 24, 3, p. 353-363 11 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations
2015

A tyrosine-tryptophan dyad and radical-based charge transfer in a ribonucleotide reductase-inspired maquette

Pagba, C. V., McCaslin, T. G., Veglia, G., Porcelli, F., Yohannan, J., Guo, Z., McDaniel, M. & Barry, B. A., Dec 1 2015, In : Nature communications. 6, 10010.

Research output: Contribution to journalArticle

16 Scopus citations

Dysfunctional conformational dynamics of protein kinase a induced by a lethal mutant of phospholamban hinder phosphorylation

Kim, J., Masterson, L. R., Cembran, A., Verardi, R., Shi, L., Gao, J., Taylor, S. S. & Veglia, G., Mar 24 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 12, p. 3716-3721 6 p.

Research output: Contribution to journalArticle

29 Scopus citations

Effects of naturally occurring arginine 14 deletion on phospholamban conformational dynamics and membrane interactions

Vostrikov, V. V., Soller, K. J., Ha, K. N., Gopinath, T. & Veglia, G., Jan 2015, In : Biochimica et Biophysica Acta - Biomembranes. 1848, 1, p. 315-322 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Formalin evokes calcium transients from the endoplasmatic reticulum

Fischer, M. J. M., Soller, K. J., Sauer, S. K., Kalucka, J., Veglia, G. & Reeh, P. W., Apr 15 2015, In : PloS one. 10, 4, e0123762.

Research output: Contribution to journalArticle

6 Scopus citations

Genetic algorithm optimized triply compensated pulses in NMR spectroscopy

Manu, V. S. & Veglia, G., Nov 1 2015, In : Journal of Magnetic Resonance. 260, p. 136-143 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Mapping the Hydrogen Bond Networks in the Catalytic Subunit of Protein Kinase A Using H/D Fractionation Factors

Li, G. C., Srivastava, A. K., Kim, J., Taylor, S. S. & Veglia, G., Jul 7 2015, In : Biochemistry. 54, 26, p. 4042-4049 8 p.

Research output: Contribution to journalArticle

12 Scopus citations
13 Scopus citations